TSC22D3 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 130 results for "TSC22D3"
i
  1. Data from: Systematic study of the surface plasmon resonance signals generated by cells for sensors with different characteristic lengths Dryad

    DateIssued: 11-11-2014

    Description: stablish an in-depth understanding of the signals induced by mammalian cells in surface plasmon resonance (SPR) sensing. To this end, two plasmonic structures with different propagation and penetration distances were us...

  2. Offspring outcomes Dryad

    DateIssued: 05-13-2016

    Description: . Weight refers to weight at offspring infection. Family refers to family identity. Date mated refers to the date the mother was mated. Maternal egg refers to how many eggs the mother laid. Gender...

  3. Additional file 1: of An efficient method for protein function annotation based on multilayer protein networks Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3642095_D1

    Release Date: 12-16-2016

    Description: eins in the yeast PPI network. DIP141001.txt: The DIP dataset, updated to Oct.1, 2014, consists of 5017 proteins and 23115 interactions among the proteins. Domain.txt: The domain data derived from Pfam database, including 1107 different types of domains among 3056 proteins. FP-MPN.exe: The FP-MPN alg...

  4. Transcription profiling of S. cerevisiaeAir-liquid interfacial biofilm vs planktonic S. cerevisiae cells ArrayExpress

    ID: E-GEOD-19156

    Description: found to be depleted as measured by an enzymatic dip stick (Diastic, Bayer). Cells were pelleted and washed twice in sterile distilled water by centrifugation and then diluted 10-fold into 100 ml of Flor medium (YNB + 4% ethanol + leucine + histidine + uracil) in triplicate 250 ml beakers. Cultures were then grown statically in Flor medium at 27 C. Within a few hours following inoculation, the bulk liquid appeared to be clear, no biofilm was eviden...

  5. Detection of genes acting downsteram of ectopically expressed TCP/CYC2 transcription factors in Arabidopsis thaliana ArrayExpress

    ID: E-GEOD-62213

    Description: . Arabidopsis plants were transformed (via floral dip) with respective constructs and also with the empty vector (pBar). Transgenic plants (T1) with petal size deviation from the control (plants transformed with the empty vector and wild type) were selfed and resulting T2 lines with petal size deviations from control were selected. Inflorescence buds from secondary inflorescences were harvested from transgenic T2 plants that formed smaller (#0255 or #0569) or larger (#0577) petals in the main inflorescence. Total RNA was isolated and sent to the Integrated Functional Genomics Service at the University of Münster, Germany, which carried out probe preparation, hybridization and statistical analysis of the data. Differential gene expression was always determined from a comparison of gene expression from #0522, #0569 and #0577, respectively, against the control (#pBar; inflorescence gene expression in plants transformed with an empty vector)....

  6. Epigenetic and transcriptional landscapes of Dnmt3a-deficient olfactory sensory neurons OmicsDI

    ID: E-GEOD-52464

    Date Released: 12-23-2014

    Description: SN-expressed genes, and the alteration of odorant-induced transcriptional responses of immediate early genes. Together, these results demonstrate that Dnmt3a is necessary to define the neuronal transcriptional state and may be broadly involved in refining expression profiles within differentiated cells. To determine the contributions of Dnmt3a to the DNA modification and transcriptional landscapes of a post-mitotic neuronal population, we performed DNA immunoprecipitation (DIP-seq) using antibodies specific for 5mC and 5hmC and rRNA-depleted transcriptional profiling (RNA-seq) coupled to high-throughput sequencing using genomic DNA or RNA from FACS-isolated mature olfactory sensory neurons (mOSNs) from main olfactory epithelium (MOE) of Dnmt3a wildtype (WT), heterozygous-null (Het), or homozygous-null (KO) 3-week old mice. Similarly, to compare this information with other epigenetic features of the MOE, we performed H3K4me1 (WT), H3K27ac (WT), and H3K27me3 (WT and K...

  7. Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics OmicsDI

    ID: E-GEOD-56429

    Date Released: 01-27-2015

    Description: in various human pathologies. In mammals, the TET family of dioxygenases can oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) in a stepwise manner. 5fC and 5caC are selectively recognized and excised by mammalian thymine DNA glycosylase (TDG), and ...

  8. Complementary Expression of Immunoglobulin Superfamily Ligands and Receptors in Synaptic Pairs in the Drosophila Visual System OmicsDI

    ID: E-GEOD-68235

    Date Released: 12-18-2015

    Description: gging, we demonstrate that 21 paralogs of the Dpr family, a subclass of Immunoglobulin (Ig)-domain containing proteins, are expressed in unique combinations in homologous neurons with different layer-specific synaptic connections. Dpr interacting proteins (DIPs), comprising nine paralogs of another subclass of Ig superfamily proteins, are expressed in a complementary layer-specific fashion in a subset of synaptic partners. We propose that pairs of Dpr/DIP paralogs contribute to layer-specific patterns of synaptic connectivity. Conclusions: This complexity is mirrored by the complexity of the cell surface and secreted molecules expressed by each of the R cell and lamina neurons profiled in this study. How this complexity contributes to specificity remains elusive, but the ...

  9. Pacific salmon gill samples: fate tracking at spawning grounds OmicsDI

    ID: E-GEOD-22347

    Date Released: 05-02-2014

    Description: exit, situated 100 km from the ocan. Females were dip-netted out of the entrance of the spawning channel, and placed into a sampling trough with flowing ambient water for the gill biopsy procedure and tagged with Petersen discs and returned to the spawning channel. Moribund fish were recovered daily and their gonads examined to assess whether they had spawned or not. Gene expression was assayed on the GRASP salmonid 32K cDNA microarray....

  10. A library of yeast transcription factor motifs OmicsDI

    ID: E-GEOD-12349

    Date Released: 05-03-2014

    Description: s Protein binding microarray (PBM), ChIP-chip and DIP-chip experiments of yeast transcription factor DNA-binding domains were performed. Briefly, the PBMs involved binding GST-tagged DNA-binding proteins to custom-designed, double-stranded 44K Agilent microarrays in order to determine their sequence preferences. The method is described in Berger et al., Nature Biotechnology 2006. A key feature is that the microarrays are composed of de Bruijn sequences that contain each 10-base sequence once and only once, providing an evenly balanced sequence distribution. Individual de Bruijn sequences have different properties, including representation of gapped patterns. Here we provide the data transformed into median intensities for all 32,896 8-base sequences, Z-scores for these intensities, and E-scores. E-scores are a modified version of AUC, and describe how well each 8-mer ranks the intensities of the spots. In general the E-scores are slightly more reproducible than Z-scores, but contain less information about relative binding affinity. Additional experimental details are found in Berger et al., Nature Biotechnology 2006, Berger et al., Cell 2008, and the accompanying Supplementary information. Raw 35-mer array data is available on the web link provided...

  11. Role of Serine 134 phosphorylation of the glucocorticoid receptor (GR) in glucocorticoid signaling OmicsDI

    ID: E-GEOD-28912

    Date Released: 06-26-2012

    Description: come directly activated. Here we report the human glucocorticoid receptor (GR) Serine 134 as a novel target for p38 MAPK. Unlike most other phosphorylation events that occur on the GR, phosphorylation of Ser134 was found to be hormone-independent in several human and rat c...

  12. Diverse habitats of pseudotachylytes in the Alpine Fault Zone and relationships to current seismicity Figshare

    ID: doi:10.6084/M9.FIGSHARE.3452951

    Release Date: 06-21-2016

    Description: overprinted pseudotachylytes represent the down-dip termination of large fault ruptures in a zone that would usually fail by aseismic creep. Type (iv) pseudotachylytes were formed at shallower depths (4–7 km) in a damage zone around the fault principal slip surface. Rare amygdules indicate that the fault zone locally contained free fluids....

  13. Pacific salmon gill samples: fate tracking at spawning grounds ArrayExpress

    ID: E-GEOD-22347

    Description: exit, situated 100 km from the ocan. Females were dip-netted out of the entrance of the spawning channel, and placed into a sampling trough with flowing ambient water for the gill biopsy procedure and tagged with Petersen discs and returned to the spawning channel. Moribund fish were recovered daily and their gonads examined to assess whether they had spawned or not. Gene expression was assayed on the GRASP salmonid 32K cDNA microarray....

  14. Diverse habitats of pseudotachylytes in the Alpine Fault Zone and relationships to current seismicity Figshare

    ID: doi:10.6084/M9.FIGSHARE.3452951.V1

    Release Date: 06-21-2016

    Description: overprinted pseudotachylytes represent the down-dip termination of large fault ruptures in a zone that would usually fail by aseismic creep. Type (iv) pseudotachylytes were formed at shallower depths (4–7 km) in a damage zone around the fault principal slip surface. Rare amygdules indicate that the fault zone locally contained free fluids....

  15. Data from: Switching among natal and auxiliary hosts increases vulnerability of Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae) to insecticides Dryad

    DateIssued: 04-19-2017

    Description: erate applied insecticides was studied using leaf-dip bioassay methods. Host switching demonstrated a significant role in altering the vulnerability of S. exigua populations to tested insecticides. Spodoptera exigua sourced from castor, when switched host to okra and spinach, exhibited 50% higher mortality when treated with emamectin benzoate. This trend in mortality was consistent upon complete host switch cycle (natal—auxiliary—natal host). However, the highest increase (92%) in vulnerability was recorded when the larvae were shifted to spinach from cotton. In general, chlorpyrifos and lufenuron had highest efficacies in terms of larval mortality. The findings of present studies provide insights to a better understanding the behavior of polyphagous pests and the role of different host plants in altering the susceptibility of these pests against applied insecticides. Ultimately the results warrant that due consideration should be given to cropping p...

  16. Space use by mottled sculpin and prey patch dynamics in a southern Appalachian stream. Dryad

    DateIssued: 05-30-2016

    Description: found that patch abandonment by adult sculpin was induced by changes in the local abundance of invertebrate prey. In contrast to adults, patch use by juveniles appeared to be controlled primarilly by size-dependent competitive interactions. These results indicate that the dynamics of patch use by sculpin are controlled simultaneously by the dynamics of their patchily distributed prey and age/size dependent competitive interactions.1.We sampled sculpin population seasonally (Spring, Early and Late Summer, Autumn) in each of four years (1994, 1995, 1996, 1997). Within each season we made a series of four sampling passes. During each pass we snorkeled the study site and capture individual sculpin with dip nets. Individuals were weighed (nearest .01g) and measured (nearest 1mm) and given a unique mark using acrylic paints injected subcutaneously. We mapped the location of each individual using triangulation procedures. Individual movements were characterized as the distance between subsequent captures of the same individual over time. We measured microhabitat variables at each lo...

  17. Detection of genes acting downsteram of ectopically expressed TCP/CYC2 transcription factors in Arabidopsis thaliana OmicsDI

    ID: E-GEOD-62213

    Date Released: 10-19-2014

    Description: . Arabidopsis plants were transformed (via floral dip) with respective constructs and also with the empty vector (pBar). Transgenic plants (T1) with petal size deviation from the control (plants transformed with the empty vector and wild type) were selfed and resulting T2 lines with petal size deviations from control were selected. Inflorescence buds from secondary inflorescences were harvested from transgenic T2 plants that formed smaller (#0255 or #0569) or larger (#0577) petals in the main inflorescence. Total RNA was isolated and sent to the Integrated Functional Genomics Service at the University of Münster, Germany, which carried out probe preparation, hybridization and statistical analysis of the data. Differential gene expression was always determined from a comparison of gene expression from #0522, #0569 and #0577, respectively, against the control (#pBar; inflorescence gene expression in plants transformed with an empty vector)....

  18. Comparative transcriptional profiling of rice undergoing infection by X. oryzae pv. oryzae or by X. oryzae pv. oryzicola BioProject

    ID: PRJNA117499

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: inversion of the flats for inoculation (modified dip-inoculation method, Niño-Liu et al, 2005, Journal of Phytopathology) seeds were sown through 1-cm perforations in a fibreglass tray resting on top of the pots. Peters Professional Fertilizer and iron chelate micronutrient were applied with watering every two days at rates of 0.25 and 4.5 g/L, respectively, until the day before inoculation. - Bacterial Strains and preparation of inoculum: Xoo strain PXO99A and Xoc strain BLS256 were used. For each, a single colony from a glucose yeast extract (GYE) agar plate was transferred to 5 ml of GYE liquid medium and incubated for 24 h at 28ºC with constant shaking at 250 rpm. Subsequently, 2 ml of this culture was transferred to 300 ml of fresh GYE liquid medium and incubated as above for an additional 18 h. Cells were pelleted by centrifugation at 4000 rpm. for 10 min, washed twice and resuspended in sterile 10 mm MgCl2 to an OD600 of 0.05, yielding 7 liters of inoculum. Tween-20 was added to a final concentration of 0.5%. - Modified dip-inoculation method: Fourteen days after sowing, and 2 h after the beginning of the light period, seedlings were inverted into inoculum, one flat each for Xoo, Xoc and Mock inoculum consisting of sterile 10 mM MgCl2 with 0.5% Tween-20, and vaccuum infiltrated at 500mm Hg for two minutes, two consecutive times, i...
  19. Analysis of the 17β-estradiol (17βE2)-, and coumestrol-regulated transcriptomes in MCF-7 cells NURSA

    Keywords: epithelium MCF-7 cells

    Description: Human MCF-7 breast cancer cells were treated for 24 h with and without 30 pM 17βE2, or 1 µM or 2 µM Coum.

    ID: 10.1621/VaHNVdvd3n

    dataset.creators: Dip R
  20. Air-liquid interfacial biofilm vs planktonic S. cerevisiae cells BioProject

    ID: PRJNA120711

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: found to be depleted as measured by an enzymatic dip stick (Diastic, Bayer). Cells were pelleted and washed twice in sterile distilled water by centrifugation and then diluted 10-fold into 100 ml of Flor medium (YNB + 4% ethanol + leucine + histidine + uracil) in triplicate 250 ml beakers. Cultures were then grown statically in Flor medium at 27°C. Within a few hours following inoculation, the bulk liquid appeared to be clear, no biofilm...

Displaying 20 of 130 results for "TSC22D3"