THOC5 | bioCADDIE Data Discovery Index
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Displaying 39 of 39 results for "THOC5"
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  1. THO5B_XENLA UniProt:Swiss-Prot

    ID: Q7ZXA8

    Description: THO complex subunit 5 homolog B Nuclear localization signal

  2. THOC5 controls 3´end-processing of immediate early genes via interaction with CPSF100 BioProject

    ID: PRJNA255638

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Genome-wide gene expression analysis in Thoc5- and CFIm68-depleted HeLa cells BioProject

    ID: PRJNA181059

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. molecules of human hepatocellular carcinoma using THOC5, a member of the transcription/export (TREX) complex, depleted system... BioProject

    ID: PRJNA287802

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. THO5A_XENLA UniProt:Swiss-Prot

    ID: Q6DFL5

    Description: THO complex subunit 5 homolog A Nuclear localization signal

  6. molecules of human hepatocellular carcinoma using THOC5, a member of the transcription/export (TREX) complex, depleted system... OmicsDI

    ID: E-GEOD-70178

    Date Released: 12-02-2015

    Description: encing of HCC that 161 putative driver genes are associated with 11 recurrently altered pathways, suggesting that we need to inhibit these multiple pathways for HCC therapy. THOC5, a member of transcription/export (TREX) complex, that plays a role in less than 1% of mRNA processing in normal cells such as fibroblasts or macrophages, is not required for maintenance of mature hepatocytes. In this study, we have examined t...

  7. THOC5, a member of the mRNA export complex, is essential for hematopoiesis in vivo and is required for CSF-1 induced macrophage differentiation ArrayExpress

    ID: E-GEOD-41170

    Description: THOC5, a member of the mRNA export complex, is essential for hematopoiesis in vivo and is required for CSF-1 ind...

  8. THOC5 controls 3´end-processing of immediate early genes via interaction with CPSF100 OmicsDI

    ID: E-GEOD-59561

    Date Released: 11-08-2014

    Description: signals is tightly regulated at multiple stages. THOC5, a member of the TREX (transcription/export) complex plays a role in expression of only a subset of constitutively active genes. In this report, we show that THOC5 plays a...

  9. molecules of human hepatocellular carcinoma using THOC5, a member of the transcription/export (TREX) complex, depleted system... ArrayExpress

    ID: E-GEOD-70178

    Description: encing of HCC that 161 putative driver genes are associated with 11 recurrently altered pathways, suggesting that we need to inhibit these multiple pathways for HCC therapy. THOC5, a member of transcription/export (TREX) complex, that plays a role in less than 1% of mRNA processing in normal cells such as fibroblasts or macrophages, is not required for maintenance of mature hepatocytes. In this study, we have examined t...

  10. Genome-wide gene expression analysis in Thoc5- and CFIm68-depleted HeLa cells ArrayExpress

    ID: E-GEOD-42327

    Description: polyadenylation site choice, was co-purified with Thoc5, a component of human THO/TREX. Microarray analysis using human HeLa cells reveals knockdown of Thoc5 affects the expression of a subset of non-heat shock genes. Notably, depletio...

  11. THOC5, a member of the mRNA export complex, is essential for hematopoiesis in vivo and is required for CSF-1 induced macrophage differentiation BioProject

    ID: PRJNA176023

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. THOC5, a member of the mRNA export complex, is essential for hematopoiesis in vivo and is required for CSF-1 induced macrophage differentiation OmicsDI

    ID: E-GEOD-41170

    Date Released: 05-03-2014

    Description: THOC5, a member of the mRNA export complex, is essential for hematopoiesis in vivo and is required for CSF-1 ind...

  13. THOC5 controls 3´end-processing of immediate early genes via interaction with CPSF100 ArrayExpress

    ID: E-GEOD-59561

    Description: signals is tightly regulated at multiple stages. THOC5, a member of the TREX (transcription/export) complex plays a role in expression of only a subset of constitutively active genes. In this report, we show that THOC5 plays a...

  14. Genome-wide gene expression analysis in Thoc5- and CFIm68-depleted HeLa cells OmicsDI

    ID: E-GEOD-42327

    Date Released: 06-02-2014

    Description: polyadenylation site choice, was co-purified with Thoc5, a component of human THO/TREX. Microarray analysis using human HeLa cells reveals knockdown of Thoc5 affects the expression of a subset of non-heat shock genes. Notably, depletio...

  15. THOC5_SCHPO UniProt:Swiss-Prot

    ID: Q9USR5

    Description: Uncharacterized THOC5 family protein

  16. The THO complex regulates pluripotency gene mRNA export to control embryonic stem cell self-renewal and somatic cell reprogramming (microarray) ArrayExpress

    ID: E-GEOD-51496

    Description: derstood. Here we describe a critical role of the THO complex in ESC self-renewal and differentiation. We show that THO preferentially interacts with pluripotency gene transcripts through Thoc5, and is required for self-renewal at least in part by regulating their export and expression. During differentiation, THO loses its interaction with those transcripts d...

  17. Splicing-independent loading of TREX on nascent RNA is required for efficient transcription of dual-strand piRNA clusters in Drosophila BioProject

    ID: PRJNA315501

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: The conserved THO/TREX complex is critical for pre-mRNA processing and mRNA nuclear export. In Metazoa, TREX is loaded on nasc...
  18. The THO complex regulates pluripotency gene mRNA export to control embryonic stem cell self-renewal and somatic cell reprogramming (microarray) BioProject

    ID: PRJNA223316

    Keywords: Transcriptome or Gene expression

    Access Type: download

  19. The THO complex regulates pluripotency gene mRNA export to control embryonic stem cell self-renewal and somatic cell reprogramming (RNA-IP) ArrayExpress

    ID: E-GEOD-48436

    Description: derstood. Here we describe a critical role of the THO complex in ESC self-renewal and differentiation. We show that THO preferentially interacts with pluripotency gene transcripts through Thoc5, and is required for self-renewal by regulating their export and expression. During differentiation, THO loses its interaction with those transcripts due to reduced

  20. Homo sapiens : Illumina sequencing of CFIm68 binding regions in Hela cells BioProject

    ID: PRJDB2593

    Keywords: Other

    Access Type: download

    dataset.description: Genome-wide CFIm68 binding in Hela cells was examined under normal and Thoc5-depleted conditions
  21. The THO complex regulates pluripotency gene mRNA export to control embryonic stem cell self-renewal and somatic cell reprogramming (microarray) OmicsDI

    ID: E-GEOD-51496

    Date Released: 06-03-2014

    Description: derstood. Here we describe a critical role of the THO complex in ESC self-renewal and differentiation. We show that THO preferentially interacts with pluripotency gene transcripts through Thoc5, and is required for self-renewal at least in part by regulating their export and expression. During differentiation, THO loses its interaction with those transcripts d...

  22. THOC5_RAT UniProt:Swiss-Prot

    ID: Q68FX7

    Description: Removed THO complex subunit 5 homolog Interaction with THOC7 Interaction with CSF1R Nuclear localizat...

  23. THOC5_XENTR UniProt:Swiss-Prot

    ID: Q28DG8

    Description: THO complex subunit 5 homolog Nuclear localization signal

  24. Using tiling arrays to precisely detect DNA targets of THO in yeast BioProject

    ID: PRJNA146431

    Keywords: Epigenomics

    Access Type: download

  25. THOC6_MOUSE UniProt:Swiss-Prot

    ID: Q5U4D9

    Description: THO complex subunit 6 homolog WD 1 WD 2 WD 3 WD 4 WD 5 WD 6 WD 7 Phosphoserine

  26. THOC3_ARATH UniProt:Swiss-Prot

    ID: Q9FKT5

    Description: THO complex subunit 3 WD 1 WD 2 WD 3 WD 4 WD 5 WD 6 In attex1-2; reduced levels of endogenous...

  27. The THO complex regulates pluripotency gene mRNA export to control embryonic stem cell self-renewal and somatic cell reprogramming (RNA-IP) OmicsDI

    ID: E-GEOD-48436

    Date Released: 06-03-2014

    Description: derstood. Here we describe a critical role of the THO complex in ESC self-renewal and differentiation. We show that THO preferentially interacts with pluripotency gene transcripts through Thoc5, and is required for self-renewal by regulating their export and expression. During differentiation, THO loses its interaction with those transcripts due to reduced

  28. The THO complex regulates pluripotency gene mRNA export to control embryonic stem cell self-renewal and somatic cell reprogramming (RNA-IP) BioProject

    ID: PRJNA210136

    Keywords: Transcriptome or Gene expression

    Access Type: download

  29. Genome-wide binding of THO and Sub2 in Saccharomyces cerevisiae ArrayExpress

    ID: E-GEOD-24960

    Description: THO/TREX is a conserved nuclear complex that functions in mRNP biogenesis and prevents transcription-

  30. THOC6_RAT UniProt:Swiss-Prot

    ID: Q6AY87

    Description: THO complex subunit 6 homolog WD 1 WD 2 WD 3 WD 4 WD 5 WD 6 WD 7 Phosphoserine

  31. THOC6_DANRE UniProt:Swiss-Prot

    ID: Q5XJS5

    Description: THO complex subunit 6 homolog WD 1 WD 2 WD 3 WD 4 WD 5 WD 6

  32. THOC3_BOVIN UniProt:Swiss-Prot

    ID: Q29RH4

    Description: Removed THO complex subunit 3 WD 1 WD 2 WD 3 WD 4 WD 5 WD 6 N-acetylalanine

  33. Genome-wide binding of THO and Sub2 in Saccharomyces cerevisiae BioProject

    ID: PRJNA132001

    Keywords: Epigenomics

    Access Type: download

  34. THOC5_CHICK UniProt:Swiss-Prot

    ID: Q5ZJK1

    Description: THO complex subunit 5 homolog Nuclear localization signal

  35. THOC7_BOVIN UniProt:Swiss-Prot

    ID: Q3SZ60

    Description: Removed THO complex subunit 7 homolog Interaction with THOC5 Interaction with NIF3L1 N-acetylglycine ...

  36. Genome-wide binding of THO and Sub2 in Saccharomyces cerevisiae OmicsDI

    ID: E-GEOD-24960

    Date Released: 05-03-2014

    Description: THO/TREX is a conserved nuclear complex that functions in mRNP biogenesis and prevents transcription-

  37. Using tiling arrays to precisely detect DNA targets of THO in yeast ArrayExpress

    ID: E-GEOD-32980

    Description: ed DNA from wild type cells or from mutant of the THO complex was analyzed by tiling arrays to precisely detect DNA targets of THO in yeast. DNA coming ...

  38. Structure of mRNA export factors PDB

    ID: PDB:5SUP

    Description: ATP-dependent RNA helicase SUB2, YRA1/RNA Complex

  39. Genomic structure, evolution and molecular classification of acute myeloid leukemia BioProject

    ID: PRJNA287683

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: tation. Amongst these, mutations in chromatin and spliceosome genes demarcate a molecularly heterogeneous subgroup enriched for older AML patients currently classified as intermediate risk and results in adverse prognosis. Two- and three-way genetic interactions often implicating rare genes/mutation-hotspots, markedly redefined clinical response and long-term curability, with the NPM1:DNMT3A:FLT3ITD genotype (6% patients) identifying poor prognosis disease, whereas within the same class NPM1:DNMT3A:NRASG12/13 (3%) associated with favorable outlooks. Conclusions: 79% of AML is molecularly classified in 12 genomic subgroups. These represent distinct molecular phylogenies, implicating complex genotypes. Delineation of higher-order genomic relationships, guide the development of personally tailored classification, prognostication and clinical protocols. Similar studies across cancer types are warranted. Overall design: Gene expression was profiled in 46 AML samples [n=18 AML cases with MYC mutations and n=28 AML cases with MYC wild-type]....

Displaying 39 of 39 results for "THOC5"