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Displaying 20 of 408 results for "THBS1"
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  1. UNC5C_RAT UniProt:Swiss-Prot

    ID: Q761X5

    Description: lular Helical Cytoplasmic Ig-like Ig-like C2-type TSP type-1 1 TSP type-1 2 ZU5 Death Interaction with DCC Cleavage; by caspase-3 Phosp...

  2. Transcription profiling of mouse colon carcinomas over-expressing c-Myc OmicsDI

    ID: E-MEXP-757

    Date Released: 05-02-2014

    Description: orrelated with down-regulation of anti-angiogenic thrombospondin-1 (Tsp1) and related proteins, such as connective tissue growth factor (CTGF). Both Tsp1 and CTGF are predicted targets for repression by the miR-17-92 microRNA cluster, which was upregulated in RasMyc colonocytes. Indeed, miR-17-92 knock-down with antisense 2’-O-methyl oligoribonucleotides partly restored Tsp1 and CTGF expression, and conversely, transduction of Ras-only cells with a miR-17-92-encoding retrovirus reduced Tsp1 and CTGF levels. Importantly, miR-17-92-transduced cells formed larger, better perfused tumors. These findings establish a role for microRNAs i...

  3. Gene expression profiling of MT-2 cells treated with interferon-alpha and ascorbic acid (dose response) BioProject

    ID: PRJNA151017

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Background: Clear guidelines for therapy of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) are missing due to the lack of randomized double-...
  4. Cpicta_MixedSex_DailyNestTemps Dryad

    DateIssued: 04-23-2013

    Description: the thermosensitive period for sex determination (TSP, July) in 16 natural painted turtle (Chrysemys picta) nests. Each of these nests resulted in the production of both male and female offspring (i.e. mixed-sex nests). Temperature data were collected using thermal data loggers within...

  5. Microarray analysis of gene expression profiles in response to tomato leaves extract treatment in MCF-7 breast cancer cells BioProject

    ID: PRJNA148699

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: cells treated with tomato leaves extract (TLE) in 1 hr and 48 hrs of treatment. Several of genes with p < 0.05 and fold-change cut-off <2.00 from human genome had significantly changed after the treatments. Its showed the greatest roles in cancer cells growth and were found either to b...
  6. SOLUTION STRUCTURE OF AN RNA-DNA HYBRID DUPLEX CONTAINING A 3'-THIOFORMACETAL LINKER AND AN RNA A-TRACT, NMR, 8 STRUCTURES PDB

    ID: PDB:1AC3

    Description: 5'-D(*CP*GP*CP*GP*TP*TSP*TCPP*TP*GP*CP*GP*C)-3'

  7. Gene expression profiling of MT-2 cells treated with interferon-alpha and ascorbic acid (dose response) ArrayExpress

    ID: E-GEOD-34572

    Description: Background: Clear guidelines for therapy of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) are missing due to the lack of randomized double-...

  8. Rice Yields Enhanced through Integrated Management of Cover Crops and Phosphate Rock in Phosphorus-deficient Ultisols in West Africa Dataverse

    Description: e without P or with P from triple superphosphate (TSP) and Malian Tilemsi Rock P. The P response of 20 cover crops was field-evaluated using TSP and Rock P. In both experiments, the fertilized cover crops were followed by upland rice without mineral N or P application. Mean rice grain yield and agronomic residual P-use efficiency were similar for both P sources. In the field,

    Person: Oikeh, S.O. Somado, E. A. Sahrawat, K.L. Touré, A. Diatta, S.

    Release Date: 09-20-2012

  9. Gene expression signatures and molecular markers predict response to therapy in locally advanced head and neck squamous cell carcinoma ArrayExpress

    ID: E-GEOD-23036

    Description: l (LRFS) and overall survival (OS). Tumor subtype 1, associated with low LRFS and OS, showed features of epithelial-mesenchymal transition and undifferentiation. It also overexpressed genes related to cell adhesion, NF-κB and integrin signalling pathways. Tumor subtype 3, associated with a high LRFS and OS, showed a high degree of differentiation and overexpressed genes located in chromosome regions 19q13 and 1q21. Tumor subtype 2, with a LRFS that was similar to subtype 3 and an OS similar to subtype 1, overexpressed genes involved in branching morphogenesis. ROC analysis identified genes associated with local recurrence and survival. Using qRT-PCR we confirmed the association of RAB25, DUOX1 and THBS1 expression with LRFS a...

  10. Pregnancy-associated genes contribute to antiluteolytic mechanisms in ovine coprus luteum BioProject

    ID: PRJNA207799

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: l expression of 683 genes, including SERPINE1 and THBS1. Presence of a conceptus from Day 12 to 14 also induced expression of 743 genes, i.e., ISGs (ISG15, MX1), PTX3, and IL-6 and stabilized expression of VEGF and LHR genes. In conclusion, pregnancy circumvents luteolytic pathways, and activates or stabilizes genes associated with interferon, chemokine, cell adhesion, cytoskeletal, angiogenic and epithelial to mesynchymal transition pathways in the CL. Overall design: There are 12 samples that were analyzed for the microarray, no duplicates and we increased the sample size to 50 for the RTPCR. This Series contains the Affymetrix array data only (not RT-PCR data)....
  11. NHGRI Tumor Sequencing Project (Lung Adenocarcinoma) dbGaP

    ID: phs000144.v1.p1

    Description: The Tumor Sequencing Project (TSP) Consortium is a collaboration among participants at the Baylor College of Medicine Human Genome Sequencing Center, the Broad...

    Study Types: Tumor vs. Matched-Normal

  12. Pregnancy-associated genes contribute to antiluteolytic mechanisms in ovine coprus luteum ArrayExpress

    ID: E-GEOD-47776

    Description: l expression of 683 genes, including SERPINE1 and THBS1. Presence of a conceptus from Day 12 to 14 also induced expression of 743 genes, i.e., ISGs (ISG15, MX1), PTX3, and IL-6 and stabilized expression of VEGF and LHR genes. In conclusion, pregnancy circumvents luteolytic pathways, and activates or stabilizes genes associated with interferon, chemokine, cell adhesion, cytoskeletal, angiogenic and epithelial to mesynchymal transition pathways in the CL. There are 12 samples that were analyzed for the microarray, no duplicates and we increased the sample size to 50 for the RTPCR. This Series contains the Affymetrix array data only (not RT-PCR data)....

  13. Expression analysis of the glucose deprivation-induced human tumor cell responses BioProject

    ID: PRJNA168162

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: easing the expression of angiogenesis inhibitors (THBS1, CXCL14 and CXCL10). The markers of Unfolded Protein Response (UPR) (Grp78/Bip, CHOP, ATF4, etc.) were significantly increased. The above results suggest GD may regulate angiogenesis through activation of the UPR. Overall design: UM-SCC-81B cells (human oral squamous cell carcinoma cell line) were treated with glucose deprivation (GD) for 4 hours (UM-SCC-81B-GD-4) and 24 hours (UM-SCC-81B-GD24). Cells without treatment were used as a non-treatment control (UM-SCC-81B-NT). Each sample was analyzed once, i.e., without biological replicates. The expression of the genes of interest was confirmed with real-time PCR, ELISA and Western blot....
  14. CO8B_RABIT UniProt:Swiss-Prot

    ID: P98137

    Description: Complement component C8 beta chain TSP type-1 1 LDL-receptor class A MACPF EGF-like TSP type-1

  15. CO9_TAKRU UniProt:Swiss-Prot

    ID: P79755

    Description: Complement component C9 TSP type-1 1 LDL-receptor class A MACPF EGF-like TSP type-1

  16. CO8A_RABIT UniProt:Swiss-Prot

    ID: P98136

    Description: Complement component C8 alpha chain TSP type-1 1 LDL-receptor class A MACPF EGF-like TSP type-1

  17. Transcription profiling of mouse colon carcinomas over-expressing c-Myc ArrayExpress

    ID: E-MEXP-757

    Description: orrelated with down-regulation of anti-angiogenic thrombospondin-1 (Tsp1) and related proteins, such as connective tissue growth factor (CTGF). Both Tsp1 and CTGF are predicted targets for repression by the miR-17-92 microRNA cluster, which was upregulated in RasMyc colonocytes. Indeed, miR-17-92 knock-down with antisense 2’-O-methyl oligoribonucleotides partly restored Tsp1 and CTGF expression, and conversely, transduction of Ras-only cells with a miR-17-92-encoding retrovirus reduced Tsp1 and CTGF levels. Importantly, miR-17-92-transduced cells formed larger, better perfused tumors. These findings establish a role for microRNAs in no...

  18. CO7_PIG UniProt:Swiss-Prot

    ID: Q9TUQ3

    Description: Complement component C7 TSP type-1 1 LDL-receptor class A MACPF EGF-like TSP type-1

  19. UNC5D_RAT UniProt:Swiss-Prot

    ID: F1LW30

    Description: lular Helical Cytoplasmic Ig-like Ig-like C2-type TSP type-1 1 TSP type-1 2 ZU5 Death Important for interaction with FLRT2 Cleavage; by...

  20. CO7_BOVIN UniProt:Swiss-Prot

    ID: Q29RQ1

    Description: Complement component C7 TSP type-1 1 LDL-receptor class A MACPF EGF-like TSP type-1


Displaying 20 of 408 results for "THBS1"