TEC | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 50 of 281 results for "TEC"
i
  1. Solution NMR Structure of PH Domain of Tyrosine-protein kinase Tec from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR3504C PDB

    ID: PDB:2LUL

    Description: Tyrosine-protein kinase Tec (E.C.2.7.10.2)

  2. NMR STRUCTURE OF THE SH3 DOMAIN FROM THE TEC PROTEIN TYROSINE KINASE PDB

    ID: PDB:1GL5

    Description: TYROSINE-PROTEIN KINASE TEC (E.C.2.7.1.112)

  3. Structures of human Bruton's tyrosine kinase in active and inactive conformations suggests a mechanism of activation for TEC family kinases. PDB

    ID: PDB:3K54

    Description: Tyrosine-protein kinase BTK (E.C.2.7.10.2)

  4. The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound PDB

    ID: PDB:3GEN

    Description: Tyrosine-protein kinase BTK (E.C.2.7.10.2)

  5. Genome-wide analysis of the TEC-specific Hipk2 gene knockout in mouse medullary thymic epithelial cells (mTECs) BioProject

    ID: PRJNA267718

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Identification of a stable molecular signature in breast tumor endothelial cells that persists ex vivo OmicsDI

    ID: E-GEOD-50555

    Date Released: 05-02-2014

    Description: propagation of tumor-specific endothelial cells (TEC) allows for ex vivo functional studies and gene expression profiling of clonally-derived, well-characterized subpopulations. Using a genetically-e...

  7. TEC_BPP1 UniProt:Swiss-Prot

    ID: Q06261

    Description: Protein tec

  8. Transcription profiling by high throughput sequencing of primary cTEC, mTEClo, and mTEChi harvested from wild type and Aire-deficient mice ArrayExpress

    ID: E-GEOD-65617

    Description: umerous self-antigens in thymic epithelial cells (TEC) enables the elimination of self-reactive T cells. The autoimmune regulator (Aire) is the only known molecular determinant driving pGE in the thymus but the existenc...

  9. Genome-wide analysis of the TEC-specific Hipk2 gene knockout in mouse medullary thymic epithelial cells (mTECs) ArrayExpress

    ID: E-GEOD-63432

    Description: purified mTEC subsets (CD80 low, CD80 high) from TEC-specific Hipk2 knockout mice were compared to mating wildtype control mice (floxed, Cre-). Results provide the up- or down-regulated genes, affected by the Hipk2 gene knockout. Total RNA obtained from isolated CD80 low and CD80 high mTECs of TEC

  10. imageData: an R package that aids in processing and plotting data from a Lemna-Tec Scananalyzer Dryad

    DateIssued: 11-18-2016

    Description: s traits from imaging data produced using a Lemna-Tec Scananalyzer. Growth rates between successive imagings are obtained and those for a nominated set of intervals can also be calculated. Profile or longitudinal...

  11. Human thymic epithelial cell: untransfected control vs. scramble-siRNA transfected vs. CD49e-siRNA transfected BioProject

    ID: PRJNA119437

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: mic microenvironment the thymic epithelial cells (TEC) are crucial for the maturation of T-lymphocytes because the secretion of extracellular matrix compounds, thymic hormones and cytokines and also by cell-cell contacts which can be mediated by extracellular matrix compounds and its receptors, integrins. There is evidence that extracellular matrix molecules play a fundamental role in localizing the different thymocyte stag...
  12. Genome-wide analysis of the TEC-specific Hipk2 gene knockout in mouse medullary thymic epithelial cells (mTECs) OmicsDI

    ID: E-GEOD-63432

    Date Released: 01-10-2015

    Description: purified mTEC subsets (CD80 low, CD80 high) from TEC-specific Hipk2 knockout mice were compared to mating wildtype control mice (floxed, Cre-). Results provide the up- or down-regulated genes, affected by the Hipk2 gene knockout. Total RNA obtained from isolated CD80 low and CD80 high mTECs of TEC

  13. Transcription profiling by high throughput sequencing of primary cTEC, mTEClo, and mTEChi harvested from wild type and Aire-deficient mice OmicsDI

    ID: E-GEOD-65617

    Date Released: 06-27-2016

    Description: umerous self-antigens in thymic epithelial cells (TEC) enables the elimination of self-reactive T cells. The autoimmune regulator (Aire) is the only known molecular determinant driving pGE in the thymus but the existenc...

  14. Gene Expression Data from Adult and Embryo Thymic Epithelial Cells (TEC) BioProject

    ID: PRJNA321529

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. Identification of a stable molecular signature in breast tumor endothelial cells that persists ex vivo ArrayExpress

    ID: E-GEOD-50555

    Description: propagation of tumor-specific endothelial cells (TEC) allows for ex vivo functional studies and gene expression profiling of clonally-derived, well-characterized subpopulations. Using a genetically-e...

  16. Itk-sh3 PDB

    ID: PDB:2LMJ

    Description: Tyrosine-protein kinase ITK/TSK (E.C.2.7.10.2)

  17. Differential features of Aire-induced and Aire-independent promiscuous gene expression in thymic epithelial cells BioProject

    ID: PRJNA274486

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: umerous self-antigens in thymic epithelial cells (TEC) enables the elimination of self-reactive T cells. The autoimmune regulator (Aire) is the only known molecular determinant driving pGE in the thymus but the existenc...
  18. Activation of Inflammation and Metabolic Networks in Age-related Thymic Involution. BioProject

    ID: PRJNA320761

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: nvironment, particularly thymic epithelial cells (TEC). We studied the pathogenic processes in chronological aging of the murine thymus. We used microarrays to elucidate the global gene expression and to identify a leading edge subset of age-associated genes in TEC. Analyses of the
  19. Escherichia coli strain:tEC : Escherichia coli strain:tEC Genome sequencing and assembly BioProject

    ID: PRJNA308525

    Keywords: Genome sequencing and assembly

    Access Type: download

    dataset.description: E. coli strain tEC was isolated from fecal sample of mouse and has been sequenced for genome.
  20. Identification of a stable molecular signature in breast tumor endothelial cells that persists ex vivo BioProject

    ID: PRJNA218090

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: propagation of tumor-specific endothelial cells (TEC) allows for ex vivo functional studies and gene expression profiling of clonally-derived, well-characterized subpopulations. Using a genetically-e...
  21. Crystal structure of BMX non-receptor tyrosine kinase complexed with PP2 PDB

    ID: PDB:3SXS

    Description: Cytoplasmic tyrosine-protein kinase BMX (E.C.2.7.10.2)

  22. Crystal structure of BMX non-receptor tyrosine kinase complex with dasatinib PDB

    ID: PDB:3SXR

    Description: Cytoplasmic tyrosine-protein kinase BMX (E.C.2.7.10.2)

  23. INTRAMOLECULAR ITK-PROLINE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE PDB

    ID: PDB:1AWJ

    Description: ITK

    datasetDistributions.storedIn: Protein Data Bank
  24. Solution structure of the SH2 domain of human Tyrosine-protein kinase TXK PDB

    ID: PDB:2DM0

    Description: Tyrosine-protein kinase TXK (E.C.2.7.10.2)

  25. Gene expression in thymic epithelial cells [RNA-seq] ArrayExpress

    ID: E-GEOD-53110

    Description: ted populations of mouse thymic epithelial cells (TEC). Two biological replicates of each of seven murine TEC populations were FACS sorted and sequenced....

  26. Environment analysis of the Training in Employment Courses (TEC) in ICT sector in Morocco. Figshare

    ID: doi:10.6084/M9.FIGSHARE.1190711

    Release Date: 10-02-2014

    Description:

  27. microRNA expression in thymic epithelial cells BioProject

    ID: PRJNA283357

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: d. MicroRNAs (miRNAs) are important regulators of TEC genetic programs since miRNA-deficient TECs are severely defective. However, the individual miRNAs important for TEC maintenance and function and their mechanisms of action remain unknown. Here, we demonstrate that miR-205 is highly and preferentially expressed in mTECs during both thymic ontogeny and in the postnatal thymus. This distinct expression is suggestive of functional importance for TEC biology. Genetic ablation of miR-205 in TECs, however, neither revealed a role for miR-205 in TEC function during homeostatic...
  28. Gene expression in thymic epithelial cells [RNA-seq] BioProject

    ID: PRJNA230859

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ted populations of mouse thymic epithelial cells (TEC). Overall design: Two biological replicates of each of seven murine TEC populations were FACS sorted and sequenced....
  29. Gene expression in thymic epithelial cells [RNA-seq] OmicsDI

    ID: E-GEOD-53110

    Date Released: 12-10-2014

    Description: ted populations of mouse thymic epithelial cells (TEC). Two biological replicates of each of seven murine TEC populations were FACS sorted and sequenced....

  30. Expression data from tumor-associated endothelial cells of hepatocellular carcinoma ArrayExpress

    ID: E-GEOD-51401

    Description: ultured CD31+ and CD105+ tumor endothelial cells (TEC), non-tumor endothelial cells (NEC) ,remnant cells from tumor (TC) and non-tumor liver tissue (NTC)of HCC tissues from patientswere isolat...

  31. microRNA expression in thymic epithelial cells OmicsDI

    ID: E-GEOD-68674

    Date Released: 08-19-2015

    Description: d. MicroRNAs (miRNAs) are important regulators of TEC genetic programs since miRNA-deficient TECs are severely defective. However, the individual miRNAs important for TEC maintenance and function and their mechanisms of action remain unknown. Here, we demonstrate that miR-205 is highly and preferentially expressed in mTECs during both thymic ontogeny and in the postnatal thymus. This distinct expression is suggestive of functional importance for TEC biology. Genetic ablation of miR-205 in TECs, however, neither revealed a role for miR-205 in TEC function during homeostatic...

  32. Expression data from tumor-associated endothelial cells of hepatocellular carcinoma OmicsDI

    ID: E-GEOD-51401

    Date Released: 06-03-2014

    Description: ultured CD31+ and CD105+ tumor endothelial cells (TEC), non-tumor endothelial cells (NEC) ,remnant cells from tumor (TC) and non-tumor liver tissue (NTC)of HCC tissues from patientswere isolat...

  33. CRYSTAL STRUCTURE OF THE HUMAN DERIVED SINGLE CHAIN ANTIBODY FRAGMENT (SCFV) 9004G IN COMPLEX WITH CN2 TOXIN FROM THE SCORPION CENTRUROIDES NOXIUS HOF... PDB

    ID: PDB:2YC1

    Description: SINGLE CHAIN ANTIBODY FRAGMENT 9004G, BETA-MAMMAL TOXIN CN2

    dataset.creators: Canul-Tec, J.C.
  34. Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve inhibitor TFB-TBOA and the allosteric inhibitor UCPH101 PDB

    ID: PDB:5MJU

    Description: Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1

    dataset.creators: Canul-Tec, J.C.
  35. Crystallographic structure of 3mJL2 from the germinal line lambda 3 PDB

    ID: PDB:4AIZ

    Description: V2-17 PROTEIN

  36. Structure of the thermostabilized EAAT1 cryst mutant in complex with L-ASP and the allosteric inhibitor UCPH101 PDB

    ID: PDB:5LLM

    Description: Human glutamate transporter EAAT1

    dataset.creators: Canul-Tec, J.C.
  37. Structure of the thermostabilized EAAT1 cryst-II mutant in complex with L-ASP PDB

    ID: PDB:5LLU

    Description: Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1

    dataset.creators: Canul-Tec, J.C.
  38. Structure of the thermostalilized EAAT1 cryst-II mutant in complex with L-ASP and the allosteric inhibitor UCPH101 PDB

    ID: PDB:5LM4

    Description: Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1

    dataset.creators: Canul-Tec, J.C.
  39. Crystallographic structure of an amyloidogenic variant, 3rCW, of the germinal line lambda 3 PDB

    ID: PDB:4AJ0

    Description: GERMINAL LINE LAMBDA 3 3RCW VARIANT

    dataset.creators: Canul-Tec, J.C.
  40. AireKO vs Black6 BioProject

    ID: PRJNA92051

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: TEC (B6 vs Aire KO). Thymic epithelial cells from B6 strain and AIRE KO are compared. Keywords: repeat sample
  41. Crystallographic structure of an amyloidogenic variant, 3rC34Y, of the germinal line lambda 3 PDB

    ID: PDB:4AIX

    Description: IG LAMBDA CHAIN V-IV REGION BAU

    dataset.creators: Canul-Tec, J.C.
  42. CRYSTAL STRUCTURE OF THE HUMAN DERIVED SINGLE CHAIN ANTIBODY FRAGMENT (SCFV) 9004G IN COMPLEX WITH CN2 TOXIN FROM THE SCORPION CENTRUROIDES NOXIUS HOF... PDB

    ID: PDB:2YBR

    Description: SINGLE CHAIN ANTIBODY FRAGMENT 9004G, BETA-MAMMAL TOXIN CN2

    dataset.creators: Canul-Tec, J.C.
  43. microRNA expression in thymic epithelial cells ArrayExpress

    ID: E-GEOD-68674

    Description: d. MicroRNAs (miRNAs) are important regulators of TEC genetic programs since miRNA-deficient TECs are severely defective. However, the individual miRNAs important for TEC maintenance and function and their mechanisms of action remain unknown. Here, we demonstrate that miR-205 is highly and preferentially expressed in mTECs during both thymic ontogeny and in the postnatal thymus. This distinct expression is suggestive of functional importance for TEC biology. Genetic ablation of miR-205 in TECs, however, neither revealed a role for miR-205 in TEC function during homeostatic...

  44. Microvesicles derived from human mesenchymal stem cells protect against acute tubular injury BioProject

    ID: PRJNA113707

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: apoptosis resistance of tubular epithelial cells (TEC). In addition, MVs were found to accelerate in vivo the morphological and functional recovery of glycerol induced AKI in SCID mice by inducing TEC proliferation. The effect of MVs on the recovery of AKI was comparable to that of human MSC treatment. In vitro we found that the CD44 and beta1-integrin-dependent incorporation of MVs in TEC was required for their biological action. However, despite their internalization, RNase-treated MVs failed to induce in vitro apoptosis resistance and TEC proliferation, and in vivo recovery from AKI, suggesting an RNA-dependent biological effect. Microarray analysis and quantitati...
  45. FGF2_MOUSE UniProt:Swiss-Prot

    ID: P15655

    Description: tor 2 Heparin-binding Heparin Phosphotyrosine; by TEC Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)...

  46. FGF2_SHEEP UniProt:Swiss-Prot

    ID: P20003

    Description: chment site; atypical Heparin Phosphotyrosine; by TEC Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)...

  47. FGF2_RABIT UniProt:Swiss-Prot

    ID: P48799

    Description: tor 2 Heparin-binding Heparin Phosphotyrosine; by TEC Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)...

  48. FGF2_BOVIN UniProt:Swiss-Prot

    ID: P03969

    Description: chment site; atypical Heparin Phosphotyrosine; by TEC Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)...

  49. TEC fluctuation during magnetically disturbed events of April 2010 on high latitude station. Figshare

    ID: doi:10.6084/M9.FIGSHARE.1179773

    Release Date: 09-24-2014

    Description:

  50. Gene expression analysis of FOXN1+ thymic endoderm cells derived from the in vitro differentiation of human embryonic stem cells BioProject

    ID: PRJNA243062

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: g GFP were targeted to FOXN1, a gene required for TEC development. Using this FOXN1GFP/w line as a read out, we developed a reproducible protocol for generating FOXN1-GFP+ thymic endoderm cells. Transcriptional profiling and flow cytometry identified Integrin-β4 (ITGB4, CD104) and HLA-DR as markers that could be used in combination with EpCAM to selectively purify FOXN1+ TEC progenitors from differentiating cultures of unmanipulated PSCs. Human FOXN1+ TEC progenitors generated from PSCs will facilitate the study of thymus biology and are a valuable resource for future applications in regenerative medicine Overall design: Human embryonic stem cells were differentiated for 30 days using the protocol described by Soh et al, 2014. The hESCs used in this...

Displaying 50 of 281 results for "TEC"