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Displaying 10 of 45 results for "TCN2"
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  1. Structure of Cobalamin-complexed Bovine Transcobalamin in trigonal crystal form PDB

    ID: PDB:2BBC

    Description: Transcobalamin II

  2. Structure of Cobalamin-complexed Bovine Transcobalamin in Monoclinic Crystal Form PDB

    ID: PDB:2BB6

    Description: bovine transcobalamin II

  3. Structure of Human Transcobalamin in complex with Cobalamin PDB

    ID: PDB:2BB5

    Description: Transcobalamin II

  4. E88 deletion mutant of CD320 in complex with TC2 PDB

    ID: PDB:4ZRQ

    Description: Transcobalamin-2, CD320 antigen

  5. Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation BioProject

    ID: PRJNA339149

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Over 80% of patients with the refractory anemia with ring sideroblasts subtype of myelodysplastic syndrome (MDS) have mutations in Splicing Factor 3B, Subunit 1 (SF3B1). We...
  6. Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice ArrayExpress

    ID: E-GEOD-57761

    Description: ce. Genetic disruption of autophagy did not cause anemia in wild-type mice but accelerated the decline in mitochondrial respiration and development of macrocytic anemia in mtDNA-mutator mice. These findings highlight a pathological feedback loop that explains how dysfunctional mitochondria can escape autophagy-mediated degradation and propagate in cells predisposed to somatic mtDNA mutations, leading to disease. We used microarrays to identify expression profiles and pathways that are differentially activated or suppressed in Ter119+ bone marrow cells isolated from phlebotomized wildtype or Polg mutant mice...

  7. Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice BioProject

    ID: PRJNA248010

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ction of the mtDNA polymerase, PolgA, and develop macrocytic anemia similar to that of patients with MDS. We observed an unexpected defect in clearance of dysfunctional mitochondria at specific stages during erythroid maturation in hematopoietic cells from aged mtDNA-mutator mice. Mechanistically, aberrant activation of mechanistic target of rapamycin signaling and phosphorylation of uncoordinated 51-like kinase (ULK) 1 in mtDNA-mutator mice resulted in proteasome mediated degradation of ULK1 and inhibition of autophagy in erythroid cells. To directly evaluate...
  8. Prevotella sp. TC2-28 : Prevotella sp. TC2-28 genome sequencing BioProject

    ID: PRJNA303336

    Keywords: genome sequencing

    Access Type: download

  9. Prevotella sp. TC2-24 : Prevotella sp. TC2-24 genome sequencing BioProject

    ID: PRJNA303337

    Keywords: genome sequencing

    Access Type: download

  10. Mycoplasma ovipneumoniae strain:TC2 : Mycoplasma ovipneumoniae strain:TC2 Genome sequencing and assembly BioProject

    ID: PRJNA253502

    Keywords: Genome sequencing and assembly

    Access Type: download

    organism.strain: TC2

Displaying 10 of 45 results for "TCN2"