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Displaying 20 of 766 results for "SUMO1"
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  1. Chromatin modification by SUMO-1 stimulates the promoters of translation machinery genes ArrayExpress

    ID: E-GEOD-41264

    Description: We determined the occupancy of SUMO-1 on chromatin in HeLa cells by use of chromatin affinity purification coupled with next generation sequenc...

  2. Genome wide occupancy of SUMO machinery in proliferative and Ras-induced senescent human primary fibroblasts ArrayExpress

    ID: E-GEOD-42211

    Description: ne of the largest groups of proteins regulated by SUMO, and their modification has generally been correlated with transcriptional repression. However, as most of the studies focus on specific sumoylated transcripti...

  3. Structure of human Senp2 PDB

    ID: PDB:1TH0

    Description: Sentrin-specific protease 2 (E.C.3.4.22.-)/Ubiquitin-like protein

  4. SUMOHeratoPHASED Dryad

    DateIssued: 04-04-2012

    Description: DNA sequence data for the gene SUMO-1 activating enzyme (sae-1) for multiple individuals for multipl...

  5. Crystal Structure of the Monobody ySMB-1 bound to yeast SUMO PDB

    ID: PDB:3QHT

    Description: Ubiquitin-like protein SMT3, Monobody ySMB-1

  6. Expression Data from Ectopic expression of SUMO-1 in C. elegans ArrayExpress

    ID: E-GEOD-19972

    Description: Transgenic C. elegans strains that express human SUMO-1 under the control of pan-neuronal (aex-3) or pan muscular (myo-4) promoters were assayed for

  7. STRUCTURE OF SUMO MODIFIED UBC9 PDB

    ID: PDB:2VRR

    Description: SUMO-CONJUGATING ENZYME UBC9 (E.C.6.3.2.19), SMALL UBIQUITIN-RELATED MODIFIER

  8. Crystal structure of human Senp2 in complex with RanGAP1-SUMO-2 PDB

    ID: PDB:2IO3

    Description: Sentrin-specific protease 2 (E.C.3.4.22.-), Small ubiquitin-related modifier

  9. SUMOHmelpomenePHASED Dryad

    DateIssued: 04-04-2012

    Description: DNA sequence data for the gene SUMO-1 activating enzyme (sae-1) for multiple individuals for multipl...

  10. CRYSTAL STRUCTURE OF SUMO MODIFIED UBIQUITIN CONJUGATING ENZYME E2-25K PDB

    ID: PDB:2BF8

    Description: UBIQUITIN-CONJUGATING ENZYME E2-25 KDA (E.C.6.3.2.19), UBIQUITIN-LIKE PROTEIN

  11. Solution Structure of Human Small Ubiquitin-Like Modifier Protein Isoform 2 (SUMO-2) PDB

    ID: PDB:2AWT

    Description: Small ubiquitin-related modifier 2

  12. NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation ArrayExpress

    ID: E-GEOD-61727

    Description: OTCH1 signaling depletes the pool of unconjugated small ubiquitin-like modifier 1 (SUMO1) and SUMO2/3 leading to increased sensitivity to perturbation of the SUMOylation cascade. Depletion of unconjugated SUMO correlates with sensitivity to inhibition of SUMOylation also in patient-derived breast cancer cell lines with constitutive NOTCH pathway activation. Our investigation suggests that SUMOylation cascade inhibitors should be further explored as targeted treatment for NOTCH-driven breast cancer. We treated MCF10A and NOTCH1 cells with either DMSO or ginkgolic acid 30 uM for 3 days. Two replicates have been analysed for each condition....

  13. Structural Basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin conjugating enzyme Ubc9 and RanGAP1 PDB

    ID: PDB:1KPS

    Description: Ubiquitin-like protein SUMO-1 conjugating enzyme (E.C.6...

  14. Gene expression analysis in the hippocampus of SUMO1 and SUMO2 transgenic mice ArrayExpress

    ID: E-GEOD-47951

    Description: Transgenic mouse lines that express His6-SUMO1 and His6-SUMO2 under the control of the neuron specific Thy1.2 promoter were generated and characterized. The effect of incre...

  15. THE STRUCTURE OF SENP1 SUMO-2 CO-COMPLEX SUGGESTS A STRUCTURAL BASIS FOR DISCRIMINATION BETWEEN SUMO PARALOGUES DURING PROCESSING PDB

    ID: PDB:2CKG

    Description: SENTRIN-SPECIFIC PROTEASE 1 (E.C.3.4.22.-)

  16. Structure of Xanthomonas campestris effector protein XopD bound to tomato SUMO PDB

    ID: PDB:5JP1

    Description: Outer protein D, Small ubiquitin-related modifier

  17. n machinery to promote transcription of Ribosomal Protein genes... BioProject

    ID: PRJEB7579

    Keywords: Other

    Access Type: download

  18. NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation BioProject

    ID: PRJNA261961

    Keywords: Transcriptome or Gene expression

    Access Type: download

  19. Crystal structure of human Senp2 in complex with preSUMO-2 PDB

    ID: PDB:2IO0

    Description: Sentrin-specific protease 2 (E.C.3.4.22.-), Small ubiquitin-related modifier

  20. A SUMOylated C-terminus fragment of glutamate transporter EAAT2 linked to inherited ALS mediates motor axon impairment ArrayExpress

    ID: E-GEOD-26070

    Description: and generating a proteolytic fragment found to be SUMO1 conjugated (CTE-SUMO1). We show here that this fragment accumulates in the nucleus of spinal cord astrocytes in vivo throughout the disease stages of the SOD1-G93A mouse model of ALS. In vitro expression in spinal cord astrocytes of the C-terminus peptide of EAAT2 (CTE), which was artificially fused to SUMO1 (CTE-SUMO1fus) to mimic the endogenous SUMOylation reaction, recapitulates the nuclear accumulatio...


Displaying 20 of 766 results for "SUMO1"