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Displaying 50 of 54 results for "SPOP"
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  1. Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2 PDB

    ID: PDB:3HSV

    Description: Speckle-type POZ protein, Core histone macro-H2A.1

  2. Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-CiSBC2 PDB

    ID: PDB:3HQM

    Description: Speckle-type POZ protein, Protein cubitus interruptus

  3. Crystal Structure of the Human SPOP C-terminal Domain PDB

    ID: PDB:4HS2

    Description: Speckle-type POZ protein

  4. Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-PucSBC1_pep1 PDB

    ID: PDB:3IVV

    Description: Speckle-type POZ protein, PucSBC1

  5. Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases:SPOPMATHx-PucSBC1_pep2 PDB

    ID: PDB:3HQL

    Description: Speckle-type POZ protein, Puckered (E.C.3.1.3.-, 3.1.3.16, 3.1.3.48)

  6. Crystal Structure of the Human SPOP BTB Domain PDB

    ID: PDB:4J8Z

    Description: Speckle-type POZ protein

  7. Solution structure of N-terminal domain of speckle-type POZ protein PDB

    ID: PDB:2CR2

    Description: Speckle-type POZ protein

  8. SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer PDB

    ID: PDB:4O1V

    Description: Speckle-type POZ protein, Phosphatidylinositol 3,4,5-trisphosphate 3-phosp...

  9. Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep1 PDB

    ID: PDB:3HQH

    Description: Speckle-type POZ protein, MacroH2A

  10. Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1 PDB

    ID: PDB:3HQI

    Description: Speckle-type POZ protein, PucSBC1

  11. Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1 PDB

    ID: PDB:3HU6

    Description: Speckle-type POZ protein, Puckered (E.C.3.1.3.-, 3.1.3.16, 3.1.3.48)

  12. Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPBTB/3-box PDB

    ID: PDB:3HTM

    Description: Speckle-type POZ protein

  13. Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-MacroH2ASBCpep1 PDB

    ID: PDB:3IVB

    Description: Speckle-type POZ protein, Core histone macro-H2A.1

  14. Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-CiSBC2 PDB

    ID: PDB:3IVQ

    Description: Speckle-type POZ protein, CiSBC2

  15. Crystal structure of the SPOP BTB domain complexed with the Cul3 N-terminal domain PDB

    ID: PDB:4EOZ

    Description: Speckle-type POZ protein, Cullin-3

  16. SPOPA_XENLA UniProt:Swiss-Prot

    ID: Q7ZX06

    Description: Speckle-type POZ protein A MATH BTB Required for nuclear localization Homo...

  17. SPOPB_XENLA UniProt:Swiss-Prot

    ID: Q0IHH9

    Description: Speckle-type POZ protein B MATH BTB Required for nuclear localization Homo...

  18. Mus musculus : SPOP mutant mouse model BioProject

    ID: PRJNA312504

    Keywords: raw sequence reads

    Access Type: download

  19. Effects of SPOP on gene expression in prostate cancer BioProject

    ID: PRJNA255304

    Keywords: Transcriptome or Gene expression

    Access Type: download

  20. SPOP_XENTR UniProt:Swiss-Prot

    ID: Q6P8B3

    Description: Speckle-type POZ protein MATH BTB Required for nuclear localization Homodi...

  21. SPOP_BOVIN UniProt:Swiss-Prot

    ID: Q0VCW1

    Description: Speckle-type POZ protein MATH BTB Required for nuclear localization Import...

  22. Effects of SPOP on gene expression in prostate cancer ArrayExpress

    ID: E-GEOD-59432

    Description: SPOP is a ubiquitin ligase adaptor frequently mutated in prostate cancer. It is involved in ubiquitination and degradation of subst...

  23. Effects of SPOP on gene expression in prostate cancer OmicsDI

    ID: E-GEOD-59432

    Date Released: 10-19-2014

    Description: SPOP is a ubiquitin ligase adaptor frequently mutated in prostate cancer. It is involved in ubiquitination and degradation of subst...

  24. Danio rerio : SPOP mutation leads to genomic instability in prostate cancer BioProject

    ID: PRJNA296414

    Keywords: transcriptome

    Access Type: download

  25. The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing BioProject

    ID: PRJNA303041

    Keywords: Other

    Access Type: download

  26. Drosophila melanogaster developmental timecourse: wild type, eve, ftz ArrayExpress

    ID: E-GEOD-14086

    Description: staged D. mel. Embryos for three genotypes: wild type, eve3 and ftz11 For additional information, please see Liu et al., 2009. Abstract: We constructed a large-scale functional network model in Drosophila melanogaster built ...

  27. Drosophila melanogaster developmental timecourse: wild type, eve, ftz OmicsDI

    ID: E-GEOD-14086

    Date Released: 05-04-2014

    Description: staged D. mel. Embryos for three genotypes: wild type, eve3 and ftz11 For additional information, please see Liu et al., 2009. Abstract: We constructed a large-scale functional network model in Drosophila melanogaster built ...

  28. SPOP_DANRE UniProt:Swiss-Prot

    ID: Q7T330

    Description: Speckle-type POZ protein MATH BTB Required for nuclear localization Homodi...

  29. SPOPL_XENLA UniProt:Swiss-Prot

    ID: Q6GR09

    Description: Speckle-type POZ protein-like MATH BTB

  30. PRJNA381797 BioProject

    Keywords: raw sequence reads

    Access Type: download

    dataset.description: f a polymorphic regulatory region associated with SPOP mutated prostate cancer on the transcriptome of PC-3 cells....
  31. Differentially expressed genes between SPOPmut and control in mouse prostate organoids BioProject

    ID: PRJNA374556

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: insight to the signaling pathways deregulated by SPOP mutation and determine the relevance of these models to human prostate cancer, we performed RNA-seq on SPOP mutant organoids ...
  32. Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: GigaxoninBTB/3-box PDB

    ID: PDB:3HVE

    Description: Gigaxonin

  33. Drosophila melanogaster developmental timecourse: wild type, eve, ftz BioProject

    ID: PRJNA112513

    Keywords: Transcriptome or Gene expression

    Access Type: download

  34. SPOLB_DANRE UniProt:Swiss-Prot

    ID: A0JMG1

    Description: Speckle-type POZ protein-like B MATH BTB (in Ref. 2; AAI25866)

  35. SPOLA_DANRE UniProt:Swiss-Prot

    ID: Q5BL35

    Description: Speckle-type POZ protein-like A MATH BTB Poly-Pro

  36. SPOPL_HUMAN UniProt:Swiss-Prot

    ID: Q6IQ16

    Description: Speckle-type POZ protein-like MATH BTB In dbSNP:rs36099753.

  37. Genome-wide maps of HIF1a binding sites in ccRCC cell line under hypoxia condition ArrayExpress

    ID: E-GEOD-54327

    Description: ia conditions. Especially, we found HIF1a bind to SPOP under hypoxia condition, which was further validated. Examination of HIF1a binding sites in Caki-2 cell line under hypoxia condition...

  38. SPOP mutation ProteomeXchange

    ID: PXD005309

    Instrument: LTQ

    Date Released: 03-20-2017

  39. Homo sapiens : Homo sapiens Targeted Locus (Loci) BioProject

    ID: PRJNA357005

    Keywords: targeted loci

    Access Type: download

    dataset.description: nome alterations had been found, like mutation of SPOP, PIK3CA, and copy number variants of PTEN (10q23), NKX3.1 (8p21). For more comprehensive understand the molecular genetics of prostate cancer, we did target next generation gene sequence of 46 prostate cancer patients using a panel of 32 prost...
  40. Genome-wide maps of HIF1a binding sites in ccRCC cell line under hypoxia condition BioProject

    ID: PRJNA236347

    Keywords: Epigenomics

    Access Type: download

    dataset.description: ia conditions. Especially, we found HIF1a bind to SPOP under hypoxia condition, which was further validated. Overall design: Examination of HIF1a binding sites in Caki-2 cell line under hypoxia condition...
  41. Drosophila melanogaster developmental timecourse: wild type, eve, ftz GEMMA

    ID: 2515

    Keywords: functional genomics

    Description: staged D. mel. Embryos for three genotypes: wild type, eve3 and ftz11 For additional information, please see Liu et al., 2009. Abstract: We constructed a large-scale functional network model in Drosophila melanogaster built ...

  42. PRJEB11591 BioProject

    Keywords: Other

    Access Type: download

    dataset.description: n H/K/NRAS, DICER1, EIF1AX, IDH1, PTEN, SOS1, and SPOP were identified in miFTC or FA. We identified a low frequency of fusion genes in miFTC (only one, PAX8–PPARG), but a high frequency of that in PTC (17.60%). The frequencies of BRAFV600E and H/K/NRAS mutations were substantially different in miFTC and cPTC, and those of FVPTC were intermediate between miFTC and cPTC. Gene expression analysis demonstrated three molecular subtypes regardless of their histological features, including Non–BRAF–Non–RAS (NBNR), as well as BRAF–like and RAS–like. The novel molecular subtype, NBNR, was associated with DICER1, EIF1AX, IDH1, PTEN, SOS...
  43. Prostate Cancer Genome Sequencing Project BioProject

    ID: PRJNA81145

    Keywords: Phenotype or Genotype

    Access Type: download

    dataset.description: aracterize the full range of somatic mutations in protein-coding genes that may drive the growth of prostate cancer, we sequenced the exonic regions of genomic and tumor DNA from over 100 patients with high-risk primary prostate cancer. Using hybrid capture and paired end D...
  44. Probing the effect of promoters on noise in gene expression using thousands of designed sequences ArrayExpress

    ID: E-GEOD-55346

    Description: gos were ligated upstream to a yellow fluorescent protein (YFP) gene with a short (100 bp) core promoter sequence taken from HIS3 gene promoter and into a low copy plasmid which also contains a TEF2 promoter deriving red fluorescent protein (mCherry). The resulting plasmids were then transformation into yeast (S. cerevisiae). Next, the pool of cells was grown in amino acid starvation condition (SCD without amino acid except Histidine), and sorted according to their YFP expression level into 32 expression bins (mCherry was used for gating one plasmid copy cells and for normalization). The DNA of the promoters in each bin were then amplified and sent to multiplexed parallel sequencing. Each sequencing result was mapped to a specific promoter and expression bin, resulting in a distribution of cells that contain each promoter across all expression bins. The following differences were applied relative to the description in Sharon et. al.(Sharon et al. 2012). The medium used both for growing the cells and for their sorting was SC-Glu-URA (synthetic complete media with 2% glucose and without uracil) medium without amino acids, except for Histidine. In order to achieve expression distributions with high resolution that would allow good assessment of expression noise, the library cells were sorted into 32 bins according to their ratio of YFP and mCherry expression level, thereby normalizing for extrinsic noise effects. Each of the two extreme expression bins contained 2% of the library cells and each of the remaining 30 bins contained 3.2%. We collected a total of 10,000,000 cells. As previously described, the mapping of cells to bins involves parallel sequencing of the amplified promoter regions. For this purpose, Illumina Hi-Seq 2000 was used to obtain >30,000,000 mapped reads. The two replicates were separately generated from the ssDNA oligo library and separately measured as described above....

  45. Prostate Cancer Genome Sequencing Project BioProject

    ID: PRJNA81143

    Access Type: download

    dataset.description: aracterize the full range of somatic mutations in protein-coding genes that may drive the growth of prostate cancer, we sequenced the exonic regions of genomic and tumor DNA from over 100 patients with high-risk primary prostate cancer. Using hybrid capture and paired end D...
  46. Homo sapiens : Homo sapiens Exome BioProject

    ID: PRJNA238157

    Keywords: exome

    Access Type: download

    dataset.description: n to be involved in the ubiquitin ligase complex (SPOP, KLHL22, TRPC4AP and RNF169). Functionally, both the CTNNB1 (G512V) and CAPRIN2 (R968H/S969C) were observed to be gain-of-functional mutations in HB. These results extend the landscape of genetic alterations in HB and highlight the dysregulation of Wnt and ubiquitin pathways in HB tumorigenesis....
  47. DAXX_CANLF UniProt:Swiss-Prot

    ID: Q5TJE1

    Description: Death domain-associated protein 6 Necessary for interaction with USP7 and ATRX Interaction with histone H3.3 Necessary for interaction with USP7 Interactio...

  48. DAXX_RAT UniProt:Swiss-Prot

    ID: Q8VIB2

    Description: Death domain-associated protein 6 Necessary for interaction with USP7 and ATRX Interaction with histone H3.3 Necessary for interaction with USP7 Interactio...

  49. Genome-wide maps of HIF1a binding sites in ccRCC cell line under hypoxia condition OmicsDI

    ID: E-GEOD-54327

    Date Released: 04-15-2014

    Description: ia conditions. Especially, we found HIF1a bind to SPOP under hypoxia condition, which was further validated. Examination of HIF1a binding sites in Caki-2 cell line under hypoxia condition...

  50. DAXX_CHLAE UniProt:Swiss-Prot

    ID: O18805

    Description: Death domain-associated protein 6 Necessary for interaction with USP7 and ATRX Interaction with histone H3.3 Necessary for interaction with USP7 Interactio...


Displaying 50 of 54 results for "SPOP"