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Displaying 50 of 5,205 results for "SLC45A2"
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  1. Data from: A missense mutation in SLC45A2 is associated with albinism in several small long haired dog breeds Dryad

    DateIssued: 04-27-2015

    Description: Homozygosity for a large deletion in the solute carrier family 45, member 2 (...

  2. Supplemental Figure 1-A topology prediction comparison for SLC45A2 Dryad

    DateIssued: 03-20-2015

    Description: A topology prediction comparison for SLC45A2 was carried out using TMHMM (v. 2.0; http://www.cbs.dtu.dk/services/ TMHMM-2.0/). a) The topology prediction for a cream Po...

  3. SLC45A2 genotypes and phenotypes of albino and control drogs Dryad

    DateIssued: 03-20-2015

    Description: lbino dog: P250L in exon 3 and G493D in exon 7 of SLC45A2. The genotypes of all the tested albino and control dogs for these two mutations and their coat colours are included in the file....

  4. Supplemental Table 1:Primers, annealing temperatures and the fragment of the SLC45A2 gene amplified. Dryad

    DateIssued: 03-20-2015

  5. Dynamic changes in the functions of Klf5 in maturing mouse corneas revealed by the changes in its target genes at postnatal days 11 and 56 ArrayExpress

    ID: E-GEOD-36229

    Description: n WT corneas between PN11 and PN56, while that of solute carrier family members increased. Conclusions: Differences in PN11 and PN56 corneal Klf5-target genes reveal dynamic changes in Klf5 functions during corneal maturation. Klf4- and Klf5-target genes do not overlap, consistent with their non-redundant roles in the mouse cornea. Wild type and Klf5-conditional null mouse corneal gene expression at postnatal day-11 and -56 was compared by Affymetrix mouse whole genome 430 2 arrays. Four age-matched PN56 WT and Klf5CN mice, and 3 age-matched PN11 WT and Klf5CN mice each were used for comparison of corneal gene expression by microarrays. Two dissected corneas from each mouse were pooled for isolation of total RNA using the RNeasy Mini kit (Qiagen, Germantown, MD). The quality and integrity of the isolated total RNA was confirmed using an Agilent Bioanalyzer. Total RNAs were amplified and labeled using a 3' IVT Express Kit (Affymetrix Inc., Santa Clara, CA), and hybridized to Affymetrix MG 430 2 chips following the protocol suggested by the manufacturer....

  6. DNA microarray reveals novel genes induced by mechanical forces in fetal lung type II epithelial cells BioProject

    ID: PRJNA93603

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: by strain. Interestingly, several members of the solute carrier family of amino acid transporters, genes involved in amino acid synthesis and development, and amiloride-sensitive epithelial sodium channel gene were induced by strain. These results were confirmed by quantitative real-time polymerase chain reaction (qRT-PCR). Thus, this study identifies genes induced by strain that may be important for amino acid signaling pathways, protein synthesis and development in fetal type II cells. In addition, these data suggest that mechanical forces may contribute to facilitate lung fluid reabsorption in preparation for birth. Ta...
  7. Directed evolution of a B3 metallo-beta-lactamase AIM-1 PDB

    ID: PDB:4P62

    Description: AIM-1 mutant (L55Q F114L F230Y)

  8. Trans. Profiling of Immortalized Melanocyte Cell Lines Identifies GPNMB as a Melanoblast-Expressed, MITF-Dependent Gene ArrayExpress

    ID: E-GEOD-10163

    Description: set contains Tyr, Tyrp1, Dct, Si, Melna, Slc24a5, Slc45a2, Slc24a4, Mitf, and Sox10, in addition to genes not previously attributed to pigmentation and genes with unknown function. Further evaluation of one gene in this cohort, Gpnmb, demonstrated an expression pattern similar to Dct, Si and Mitf. This expression is vastly reduced in MitfMi mutants embryos, indicating that it is dependent on Mitf for in vivo expression. Consistent with this notion, a highly-conserved MITF binding site resides directly upstream of human GPNMB, and deletion of this sequence dramatically reduces in vitro enhancer activity. Keywords: NIH embryo fibroblast cell line, melanocyte cell line, Ink4a, Tyrp1b, Rab38 A 32k expression arrays were generated by printing Oligo nucleotides from Operon Mouse oligo set (MV3) onto epoxy slides. Total RNA from immortalized melanocyte cell lines derived from C57BL/6J Ink4a-/- (melan-Ink4a-1), C57BL/6J Ink4a-/-; T...

  9. al Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157... PDB

    ID: PDB:4AX0

    Description: METALLO-BETA-LACTAMASE AIM-1

  10. ATG11_ARATH UniProt:Swiss-Prot

    ID: Q9SUG7

    Description: Autophagy-related protein 11 AIM (Atg8-family-interacting motif) AIM (Atg8-family-interacting motif) Ph...

  11. al Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157... PDB

    ID: PDB:4AX1

    Description: METALLO-BETA-LACTAMASE AIM-1

  12. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157 PDB

    ID: PDB:4AWY

    Description: METALLO-BETA-LACTAMASE AIM-1

  13. Gene Expression profiles of colon from VhlF/F, VhlΔIE, VhlF/F/Apcmin/+, VhlΔIE/Apcmin/+ ArrayExpress

    ID: E-GEOD-36091

    Description: absorption transporter divalent metal transporter-1 (DMT-1) was a critical event in HIF-2α-mediated colon carcinogenesis. These data provide a mechanistic basis for the widely reported link between iron accumulation and colon cancer risk. Together, our findings demonstrate that a chronic increase in HIF-2α in the colon initiates pro-tumorigenic signaling which may have important implications in developing preventive and therapeutic strategies for colon cancer. Global gene expression profiling in colon RNAs isolated from 5-week-old VhlF/F (n=4, Shah 001), VhlF/F/Apcmin/+(n=3, Shah 003), VhlΔIE (n=3, Shah 002) and VhlΔIE/Apcmin/+ mice (n=5, Shah 004)....

  14. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157 PDB

    ID: PDB:4AWZ

    Description: METALLO-BETA-LACTAMASE AIM-1

  15. Data from: Detecting genomic signatures of natural selection with principal component analysis: application to the 1000 Genomes data Dryad

    DateIssued: 03-03-2016

    Description: pproach, we consider the 1000 Genomes data (phase 1) considering 850 individuals coming from Africa, Asia, and Europe. The number of genetic variants is of the order of 36 millions obtained with a low-coverage sequencing depth (3×). The correlations between genetic variation and each principal component provide well-known targets for positive selection (EDAR, SLC24A5, SLC45A2, DARC), and also new candidate genes (APPBPP2, TP1A1, RTTN, KCNMA, MYO5C) and noncoding RNAs. In addition to identifying genes involved in biological adaptation, we identify two biological pathways involved in polygenic adaptation that are related to the innate immune system (beta defensins) and to lipid metabolism (fatty acid omega oxidation). An additional analysis of European data shows that a genome scan bas...

  16. Data from: MC1R variants affect the expression of melanocortin and melanogenic genes and the association between melanocortin genes and coloration Dryad

    DateIssued: 01-27-2017

    Description: The melanocortin-1 receptor (MC1R) gene influences coloration by altering the expression of genes acting downstream in the melanin synthesis. MC1R b...

  17. Trans. Profiling of Immortalized Melanocyte Cell Lines Identifies GPNMB as a Melanoblast-Expressed, MITF-Dependent Gene BioProject

    ID: PRJNA108359

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: set contains Tyr, Tyrp1, Dct, Si, Melna, Slc24a5, Slc45a2, Slc24a4, Mitf, and Sox10, in addition to genes not previously attributed to pigmentation and genes with unknown function. Further evaluation of one gene in this cohort, Gpnmb, demonstrated an expression pattern similar to Dct, Si and Mitf. This expression is vastly reduced in MitfMi mutants embryos, indicating that it is dependent on Mitf for in vivo expression. Consistent with this notion, a highly-conserved MITF binding site resides directly upstream of human GPNMB, and deletion of this sequence dramatically reduces in vitro enhancer activity. Keywords: NIH embryo fibroblast cell line, melanocyte cell line, Ink4a, Tyrp1b, Rab38 Overall design: A 32k expression arrays were generated by printing Oligo nucleotides from Operon Mouse oligo set (MV3) onto epoxy slides. Total RNA from immortalized melanocyte cell lines derived from C57BL/6J Ink4a-/- (melan-Ink4a-1), C57B...
  18. Trans. Profiling of Immortalized Melanocyte Cell Lines Identifies GPNMB as a Melanoblast-Expressed, MITF-Dependent Gene OmicsDI

    ID: E-GEOD-10163

    Date Released: 05-01-2014

    Description: set contains Tyr, Tyrp1, Dct, Si, Melna, Slc24a5, Slc45a2, Slc24a4, Mitf, and Sox10, in addition to genes not previously attributed to pigmentation and genes with unknown function. Further evaluation of one gene in this cohort, Gpnmb, demonstrated an expression pattern similar to Dct, Si and Mitf. This expression is vastly reduced in MitfMi mutants embryos, indicating that it is dependent on Mitf for in vivo expression. Consistent with this notion, a highly-conserved MITF binding site resides directly upstream of human GPNMB, and deletion of this sequence dramatically reduces in vitro enhancer activity. Keywords: NIH embryo fibroblast cell line, melanocyte cell line, Ink4a, Tyrp1b, Rab38 A 32k expression arrays were generated by printing Oligo nucleotides from Operon Mouse oligo set (MV3) onto epoxy slides. Total RNA from immortalized melanocyte cell lines derived from C57BL/6J Ink4a-/- (melan-Ink4a-1), C57BL/6J Ink4a-/-; T...

  19. Crystal structure of Saccharomyces cerevisiae Atg8 complexed with Atg32 AIM PDB

    ID: PDB:3VXW

    Description: Autophagy-related protein 8, Peptide from Autophagy-related protein 32

  20. Affect Intensity Measure (CAPS-AIM module) Dataverse

    Description: ly experiences his or her emotions. Items for the AIM were based on a definition which emphasized the distinction between frequency and intensity of experienced emotion. It is assumed that individuals who experience strong positive affect will also experience strong negative affect. Rs respond to the items on a six-point s...

    Release Date: 12-07-2007

  21. Study of Melanoma Risk in Australia and the United Kingdom dbGaP

    ID: phs000519.v1.p1

    Description: noma GWAS have been completed, including a "Phase 2" study by the International Melanoma Genetics Consortium (GenoMEL), a full GWAS of the Australian sample resource previously used in a pooled-DNA GWAS, and study conducted through the MD Anderson Cancer Center and the Brigham and Women's Hospital. The groups who performed these studies have recently shared data and replicated a number of new melanoma susceptibility loci. Aside from the identification of novel loci, there are two additional notable outcomes of these studies. Firstly, an examination of the o...

    Study Types: Case Set

  22. root metagenome : Environment: 1) Root fungi; 2) Vincetoxicum rossicum plant Targeted loci environmental BioProject

    ID: PRJNA275328

    Keywords: targeted loci environmental

    Access Type: download

  23. Cupriavidus sp. HMR-1 : Cupriavidus sp. HMR-1 Genome sequencing and assembly BioProject

    ID: PRJNA178926

    Keywords: Genome sequencing and assembly

    Access Type: download

  24. Pseudomonas aeruginosa : Genome sequencing of NDM-1-producing P. aeruginosa PASGNDM strains isolated in Singapore BioProject

    ID: PRJNA381838

    Keywords: Genome sequencing

    Access Type: download

  25. PRJEB13940 BioProject

    Keywords: Other

    Access Type: download

    dataset.description: ter, ethanol, EDTA), freezing time points (day 0, 1, and 4), and methods of collection (scoops, swabs, and fecal occult blood cards), against the gold standard of fecal samples frozen immediately and without fixatives. Aim 1: To test each collection method for within group reproducibility Aim 2: To test each collection method for quantitative reproducibility agains...
  26. Aims and Objectives of Teaching English in India Figshare

    ID: doi:10.6084/M9.FIGSHARE.661563.V1

    Release Date: 01-11-2016

    Description:

  27. ATG3_YEAS7 UniProt:Swiss-Prot

    ID: A6ZS81

    Description: ible region Handle region ATG8 interaction motif (AIM) Glycyl thioester intermediate N6-acetyllysine; by ESA1 N6-acetyllysine; by ESA1...

  28. Aims and Objectives of Teaching English in India Figshare

    ID: doi:10.6084/M9.FIGSHARE.661563

    Release Date: 07-04-2014

    Description:

  29. Renal Proximal Tube Epithelial Cells at 24h and 1% oxygen BioProject

    ID: PRJNA112789

    Keywords: Transcriptome or Gene expression

    Access Type: download

  30. Human hematopoietic leukemic k562 cells: control Vs CXCR4 constitutively active mutant cells BioProject

    ID: PRJNA307693

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: s the clinical applications of HSC therapies. SDF-1/CXCR4 axis plays a principle role in the homing and engraftment of hematopoietic stem/progenitor cells. Activation of CXCR4 induces cell trafficking and homing to the marrow microenvironment, where it retains hematopoietic stem cells in close contact with marrow stro...
  31. Data from: Associations among elementary school children's actual motor competence, perceived motor competence, physical activity and BMI: a cross-sec... Dryad

    DateIssued: 11-10-2016

    Description: ) of actual and perceived motor competence exist (aim 1); and to examine differences in physical activity levels (aim 2) and weight status (aim 3) among children with different motor competence-based profiles. Methods: Children's (N=361; Boys=50%; Mage=9.50±1.24yrs) actual motor competence was measured with the Test of Gross Motor Development-2 and their perceived motor competenc...

  32. rhizosphere metagenome : A combination of 454 high throughput sequencing and RNA stable isotope probing (RNA-SIP) with 13CO2 was used to monitor incor... BioProject

    ID: PRJNA327737

    Keywords: random survey

    Access Type: download

    dataset.description: The aim of the present study was 1) to characterize and compare the structure and composition of the root and rhizos...
  33. soil metagenome cultivar:MAPs : Study of microbial (fungal) community of soil of CSIR-CIMAP, Lucknow, maintained under organic vs. conventional farmin... BioProject

    ID: PRJNA343404

    Keywords: metagenome

    Access Type: download

    dataset.description: Aim of study was to evaluate the effect of bioinoculant on the growthand essential oil yield of /Ocimum basilicum /(Sweet Basil) un...
  34. soil metagenome cultivar:Patchouli “Johore” : Study of fungal microbial community of Pogostemon cablin Benth. under organic vs. conventional farmi... BioProject

    ID: PRJNA343401

    Keywords: metagenome

    Access Type: download

    dataset.description: Aim of study was to evaluate the effect of bioinoculant on the growth and essential oil yield of /Pogostemon cablin/ (patchouli) un...
  35. Genome-scale analysis of DNA methylation in rheumatic heart disease BioProject

    ID: PRJNA327796

    Keywords: Epigenomics

    Access Type: download

    dataset.description: The aim of the current study is to identify DNA methylation markers associated with rheumatic heart disease with secondary pulmonary ar...
  36. Crystal structure of LGG-1 complexed with a UNC-51 peptide PDB

    ID: PDB:5AZG

    Description: LGG-1, UNC-51 AIM

  37. Crystal structure of human DNMT1(646-1600) in complex with DNA PDB

    ID: PDB:3PTA

    Description: DNA (cytosine-5)-methyltransferase 1 (E.C.2.1.1.37)/DNA complex

  38. The crystal structure of human DNMT1(351-1600) PDB

    ID: PDB:4WXX

    Description: DNMT1

    gene.name: DNMT1, AIM, CXXC9, DNMT
  39. Tolumonas sp. BRL6-1 BioProject

    ID: PRJNA186459

    Keywords: Genome sequencing and assembly

    Access Type: download

  40. Marchantia polymorpha : Sequencing Marchantia polymorpha Kit-2 BioProject

    ID: PRJDB2464

    Keywords: Other

    Access Type: download

  41. Data from: Plasma dipeptidyl peptidase IV activity and measures of body composition in apparently healthy people Dryad

    DateIssued: 04-19-2016

    Description: Aim: Based on its regulatory action on glucagon-like peptide 1, dipeptidyl peptidase IV (DPP-IV) has increasingl...

  42. The Role of Germline Mutation and Parental Age in Autism Spectrum Disorders BioProject

    ID: PRJNA327608

    Access Type: download

    dataset.description: als through the following specific aims: Specific Aim 1 will characterize germline de novo mutations (DNMs) by whole genome sequencing in families. These studies will identify and validate ~8,000 de novo point mutations and structural variants in trios and controls to determine the parent of origin of DNMs. Specific Aim 2 will investigate the role of ROHs in ASD. We will identify ROHs base...
  43. The Role of Germline Mutation and Parental Age in Autism Spectrum Disorders BioProject

    ID: PRJNA327609

    Keywords: Phenotype or Genotype

    Access Type: download

    dataset.description: als through the following specific aims: Specific Aim 1 will characterize germline de novo mutations (DNMs) by whole genome sequencing in families. These studies will identify and validate ~8,000 de novo point mutations and structural variants in trios and controls to determine the parent of origin of DNMs. Specific Aim 2 will investigate the role of ROHs in ASD. We will identify ROHs base...
  44. Identification of circadian transcripts that are co-regulated with [Ca2+]cyt BioProject

    ID: PRJNA120947

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Our aim is to identify circadian transcripts that are co-regulated with [Ca2+]cyt, with the eventual goal of identifying genetic regula...
  45. Genome-Wide Association Study of Celiac Disease OmicsDI

    ID: phs000274.v1.p1

    Date Released:

    Description: sease, with reports that the disease frequency is 1:133 in the United States, similar to European estimates. There is recent evidence to suggest that the incidence of the disease is rising. Occult disease is frequently present with minimal classic symptoms or signs. The ratio of symptomatic to asymptomatic celiac disease is estimated to be 1:7. Some complications of celiac disease include lymphoma, osteoporosis, anemia, miscarriages, seizures, vita...

  46. Study: The role of viral and host microRNAs in the Aujeszkys disease virus during the infection process BioProject

    ID: PRJEB5032

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: With the aim of understanding miRNA roles during the Aujeszkys disease virus [ADV] (also known as suid herpesvirus type 1...
  47. Murine lung tissue: Gremlin-1 transgenic vs. wild type BioProject

    ID: PRJNA318808

    Keywords: Transcriptome or Gene expression

    Access Type: download

  48. Examine differential expression of sulf-1 and sulf-2, enzymes involved in heparan sulfate biosynthesis BioProject

    ID: PRJNA139881

    Keywords: Transcriptome or Gene expression

    Access Type: download

  49. Phase_variable_epigenetic_control_in_firmicutes BioProject

    ID: PRJEB17888

    Keywords: Other

    Access Type: download

    dataset.description: ucher et al., Nat Commun. 2014. 5:5471). The main aim of the project is to translate this biological novelty and unicum into a general paradigm. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/...
  50. Gene expression profiling of gastric cells infected by Helicobacter pylori BioProject

    ID: PRJNA288509

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ical factor in gastric carcinoma development. The aim of this work was to evaluate changes in gene expression in gastric cells induced by H. pylori. Overall design: The human gastric carcinoma-derived cell line AGS was infected with H. pylori strain 60190 (ATCC 49503) for 24 hours. RN...

Displaying 50 of 5,205 results for "SLC45A2"