SIK2 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 100 of 190 results for "SIK2"
i
  1. Genome-wide analysis of SIK2 regulated genes and pathways BioProject

    ID: PRJNA195915

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. SIK2 phosphorylation in response to glucagon or insulin in murine hepatocytes OmicsDI

    ID: PXD001032

    Date Released: 08-08-2014

    Description: The phosphorylation state of human HA-tagged-SIK2, adenovirally introduced in murine hepatocytes (C57/BL/6 strain) was analysed in unstimulated and in response to glucagon- or ...

  3. Genome-wide analysis of SIK2 regulated genes and pathways ArrayExpress

    ID: E-GEOD-45711

    Description: Identification of SIK2 regulated genes and pathways after SIK2 knock-down and overexpression of a wild-type and kinase

  4. Genome-wide analysis of SIK2 regulated genes and pathways OmicsDI

    ID: E-GEOD-45711

    Date Released: 01-17-2015

    Description: Identification of SIK2 regulated genes and pathways after SIK2 knock-down and overexpression of a wild-type and kinase

  5. Transcription profiling by array of Drosophila mutant for TORC after fasting OmicsDI

    ID: E-GEOD-10546

    Date Released: 10-18-2011

    Description: RC activity in wild type flies by stimulating the Salt Inducible Kinase 2 (SIK2)-mediated phosphorylation and subsequent degradation of TORC. Depletion of neuronal SIK2 increased TORC activity and enhanced resistance to starvation and oxidative stress in adult flies. As disruption of insulin signaling, either by ablation of insulin-producing cells (IPCs) or by mutation of the insulin receptor adaptor gene chico, also increased TORC activity, our results illustrate the importance of an insulin-regulated pathway in brain that promotes energy balance in Drosophila. Experiment Overall Design: Male fly heads were collected after 24h fasting, and RNA was extracted using RNAeasy kit....

  6. dTORC gene profiling BioProject

    ID: PRJNA107909

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: RC activity in wild type flies by stimulating the Salt Inducible Kinase 2 (SIK2)-mediated phosphorylation and subsequent degradation of TORC. Depletion of neuronal SIK2 increased TORC activity and enhanced resistance to starvation and oxidative stress in adult flies. As disruption of insulin signaling, either by ablation of insulin-producing cells (IPCs) or by mutation of the insulin receptor adaptor gene chico, also increased TORC activity, our results illustrate the importance of an insulin-regulated pathway in brain that promotes energy balance in Drosophila. Keywords: Fasting-induced gene expression Overall design: Male fly heads were collected after 24h fasting, and RNA was extracted using RNAeasy kit....
  7. Transcription profiling by array of Drosophila mutant for TORC after fasting ArrayExpress

    ID: E-GEOD-10546

    Description: RC activity in wild type flies by stimulating the Salt Inducible Kinase 2 (SIK2)-mediated phosphorylation and subsequent degradation of TORC. Depletion of neuronal SIK2 increased TORC activity and enhanced resistance to starvation and oxidative stress in adult flies. As disruption of insulin signaling, either by ablation of insulin-producing cells (IPCs) or by mutation of the insulin receptor adaptor gene chico, also increased TORC activity, our results illustrate the importance of an insulin-regulated pathway in brain that promotes energy balance in Drosophila. Experiment Overall Design: Male fly heads were collected after 24h fasting, and RNA was extracted using RNAeasy kit....

  8. SIK2_CHICK UniProt:Swiss-Prot

    ID: Q9IA88

    Description: Serine/threonine-protein kinase SIK2 Protein kinase UBA ATP Proton acceptor ATP Phosphothreonine Phosphoserine Phospho...

  9. SIK2_MOUSE UniProt:Swiss-Prot

    ID: Q8CFH6

    Description: Serine/threonine-protein kinase SIK2 Protein kinase UBA ATP Proton acceptor ATP Phosphothreonine N6-acetyllysine; by E...

  10. CRTC3_MOUSE UniProt:Swiss-Prot

    ID: Q91X84

    Description: r 3 Phosphoserine Phosphoserine Phosphoserine; by SIK2 Phosphoserine Phosphoserine Phosphoserine Phosphoserine Phosphoserine Phosphoserine Phosphoserine In isoform 2....

  11. SIK2 phosphorylation in response to glucagon or insulin in murine hepatocytes ProteomeXchange

    ID: PXD001032

    Instrument: LTQ Orbitrap; Q TRAP

    Date Released: 08-08-2014

  12. CRTC3_XENTR UniProt:Swiss-Prot

    ID: Q0IHT3

    Description: Phosphoserine Phosphothreonine Phosphoserine; by SIK2 Phosphothreonine Phosphoserine Phosphoserine Phosphoserine Phosphoserine...

  13. CRTC3_XENLA UniProt:Swiss-Prot

    ID: Q52KS4

    Description: ich Phosphoserine Phosphoserine Phosphoserine; by SIK2 Phosphothreonine Phosphoserine Phosphoserine Phosphoserine Phosphoserine...

  14. CRTC1_RAT UniProt:Swiss-Prot

    ID: Q157S1

    Description: radation Phosphoserine Phosphoserine; by SIK1 and SIK2 Phosphothreonine...

  15. IRS1_HUMAN UniProt:Swiss-Prot

    ID: P35568

    Description: on with PHIP GRB2-binding YXXM motif 1 YXXM motif 2 YXXM motif 3 YXXM motif 4 YXXM motif 5 YXXM motif 6 YXXM motif 7 YXXM motif 8 YXXM motif 9 Poly-Gly Ser-rich Poly-Ser Poly-Ser Poly-Gln Pro-rich Phosphoserine Phosphoserine; by CK2 Phosphoseri...

  16. 10059576 RGD

    Description: CRISPR/Cas9 system was used to introduce a mutation in the Sik2 gene of WKY/NCrl rat embryos.

    Creators: MCW Gene Editing Rat Resource Center

  17. CRTC2_BOVIN UniProt:Swiss-Prot

    ID: Q08E26

    Description: Removed CREB-regulated transcription coactivator 2 Required for interaction with RFWD2/COP1 Nuclear export signal Poly-Ser Ser-rich Required for ubiquitination and degradation N-ac...

  18. IRS1_MOUSE UniProt:Swiss-Prot

    ID: P35569

    Description: on with PHIP GRB2-binding YXXM motif 1 YXXM motif 2 YXXM motif 3 YXXM motif 4 YXXM motif 5 YXXM motif 6 YXXM motif 7 YXXM motif 8 YXXM motif 9 Poly-Ser Poly-Gln Poly-Gly Poly-Pro Phosphoserine Phosphoserine; by CK2 Phosphoserine; by RPS6KB1 Pho...

  19. CRTC2_RAT UniProt:Swiss-Prot

    ID: Q3LRZ1

    Description: Removed CREB-regulated transcription coactivator 2 Nuclear export signal Poly-Ser Ser-rich Required for ubiquitination and degradation N-acetylalanine Asymmetric dimethylarginine; ...

  20. IRS1_RAT UniProt:Swiss-Prot

    ID: P35570

    Description: on with PHIP GRB2-binding YXXM motif 1 YXXM motif 2 YXXM motif 3 YXXM motif 4 YXXM motif 5 YXXM motif 6 YXXM motif 7 YXXM motif 8 YXXM motif 9 Poly-Gln Poly-Pro Phosphoserine Phosphoserine; by CK2 Phosphoserine; by RPS6KB1 Phosphoserine; by RPS...

  21. Transformants of wheat GSK3/Shaggy-like kinase TaSK5 vs wild-type Col-0 ArrayExpress

    ID: E-GEOD-59556

    Description: A novel cold-inducible GSK3/Shaggy-like kinase cDNA (TaSK5) was isolated from winter wheat by a macroarray-based differential...

  22. Transformants of wheat GSK3/Shaggy-like kinase TaSK5 vs wild-type Col-0 OmicsDI

    ID: E-GEOD-59556

    Date Released: 11-08-2014

    Description: A novel cold-inducible GSK3/Shaggy-like kinase cDNA (TaSK5) was isolated from winter wheat by a macroarray-based differential...

  23. IRS1_CHLAE UniProt:Swiss-Prot

    ID: Q28224

    Description: on with PHIP GRB2-binding YXXM motif 1 YXXM motif 2 YXXM motif 3 YXXM motif 4 YXXM motif 5 YXXM motif 6 YXXM motif 7 YXXM motif 8 YXXM motif 9 Poly-Gly Ser-rich Poly-Ser Poly-Ser Poly-Ser Gln-rich Pro-rich Phosphoserine Phosphoserine; by CK2 Ph...

  24. Transformants of wheat GSK3/Shaggy-like kinase TaSK5 vs wild-type Col-0 BioProject

    ID: PRJNA255564

    Keywords: Transcriptome or Gene expression

    Access Type: download

  25. Identification of Sik3-targeting compound, pterosin B, for treatment of osteoarthritis BioProject

    ID: PRJNA305918

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: We generated conditional knockout mice that lack salt-inducible kinase 3 (Sik3) specifically in chondrocytes after birth by tamoxifen administration. Deletion of Sik3 at 2 or 8 weeks after birth increased the thickness of articular cartilage by increasing the chondrocyte population. Additionally, Sik3 deletion protected cartilage...
  26. NVP-BHG712 KiNativ -- multiple dose experiment LINCS

    Data Type: Binding Protein binding profile

    Assay: KiNativ kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1090

    protein.name: SRPK1/2
  27. Molecular insights into mild exercise-induced enhancement of spatial memory and neurogenesis: a DNA microarray approach ArrayExpress

    ID: E-GEOD-45813

    Description: ambient conditions in groups housing conditions (2-3 rats/cage). After the preliminary rearing, the animals were randomized into three groups based on the LT of treadmill running: Sedentary control (CONT, rest on treadmill), Mild Exercise (ME, below LT, 15 m/min) or Intense Exercise (IE, above LT, 40 m/min). Exercise group was habituated to run on a treadmill (KN-73, Natsume Ltd., Tokyo, Japan) for 1 (for ME) or 4 (for IE) weeks. Within a given test period, rats were able to run on the above-mentioned running speeds. After this running habituation, rats were entered into the exercise training session for 6 weeks in total. The running duration was 60 min/day and frequency was 5 times/week. Exercise training was performed between 19:00 and 22:00 (during dark phase). Rat’s body weight and physical condition were monitored until the end of training. If rats could not perform well running on each determined speed and showed poor health, those were eliminated from the study. Based on the criteria, a total of 13 rats were eliminated (bad runner - 4 rats; poor health - 7 rats). Twenty-four or thirty-six hours after the last training, rats were processed to the next step. In the microarray group, the whole brain of each animal was rapidly removed, and hippocampus was separated on ice according to the method of Glowinski and Iversen (1966), with minor modifications. Hippocampi were immediately flash-frozen in liquid nitrogen. The deep-frozen hippocampi were transferred to a pre-chilled (in liquid nitrogen) mortar and pestle, and ground to a very fine powder with liquid nitrogen. The powdered samples were stored in aliquots at -80ºC till used for further analysis. Total RNA was extracted from each sample powder (~50 mg) using the QIAGEN RNeasy Mini Kit (QIAGEN, Maryland, USA). To verify the quality of this RNA, the yield and purity were determined spectrophotometrically (NanoPhotomaterTM, IMPLEN, Munich, Germany) and visually confirmed using formaldehyde gel electrophoresis. We used the sample with a ratio of spectrophotometric absorbance at 260 nm to that at 230 (A260/A230) or 280 nm (A260/A280) above 1.8. An equal amount of RNA (1000 ng) from the five rats, randomly picked up from each exercise group (n = 5), was pooled and used for microarray analysis. In this study, we performed three combinations of comparison analysis of gene expression change. First, we compared the difference between CONT and ME (combination 1) or IE (combination 2) to confirm the exercise-intensity-dependent gene expression change. Subsequently, we made a comparison of ME with IE (combination 3) to elucidate a ME-based difference of IE inducible gene. In all combinations, total RNA (1000 ng) was labeled with either Cy3 or Cy5 dye using an Agilent Low RNA Input Fluorescent Linear Amplification Kit (Agilent Technologies Inc., CA, USA). Fluorescently labeled targets of control as well as treated samples were hybridized to the same microarray slide with 60-mer probes (4 x 44K (41,090 gene probes), rat whole genome, Agilent). A flip labelling (dye-swap or r...

  28. BMS-536924 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1098

    protein.name: JAK1(Kin.Dom.2)
  29. ALW-II-49-7 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1036

    protein.name: JAK1(Kin.Dom.2)
  30. GDC-0941 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1046

    protein.name: GCN2(Kin.Dom.2,S808G)
  31. NVP-TAE684 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1095

    protein.name: JAK1(Kin.Dom.2)
  32. KIN001-127 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1044

    protein.name: JAK1(Kin.Dom.2)
  33. CGP60474 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1040

    protein.name: GCN2(Kin.Dom.2,S808G)
  34. CI-1033 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1104

    protein.name: GCN2(Kin.Dom.2,S808G)
  35. WZ4002 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1055

    protein.name: JAK1(Kin.Dom.2)
  36. LY-317615 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1140

    protein.name: GCN2(Kin.Dom.2,S808G)
  37. Gefitinib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1142

    protein.name: GCN2(Kin.Dom.2,S808G)
  38. HG-14-10-04 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1120

    protein.name: GCN2(Kin.Dom.2,S808G)
  39. ABT-869 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1163

    protein.name: GCN2(Kin.Dom.2,S808G)
  40. INCB018424 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1154

    protein.name: GCN2(Kin.Dom.2,S808G)
  41. VX-745 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1159

    protein.name: GCN2(Kin.Dom.2,S808G)
  42. AT-7519 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1172

    protein.name: GCN2(Kin.Dom.2,S808G)
  43. GW843682 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1018

    protein.name: GCN2(Kin.Dom.2,S808G)
  44. CEP-701 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1170

    protein.name: GCN2(Kin.Dom.2,S808G)
  45. Dabrafenib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1117

    protein.name: GCN2(Kin.Dom.2,S808G)
  46. ZM-447439 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1033

    protein.name: GCN2(Kin.Dom.2,S808G)
  47. TG-101348 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1155

    protein.name: GCN2(Kin.Dom.2,S808G)
  48. XMD11-50 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1056

    protein.name: GCN2(Kin.Dom.2,S808G)
  49. GW-5074 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1008

    protein.name: GCN2(Kin.Dom.2,S808G)
  50. CP724714 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1015

    protein.name: GCN2(Kin.Dom.2,S808G)
  51. JNK-IN-5A KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1067

    protein.name: GCN2(Kin.Dom.2,S808G)
  52. AZD-6244 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1137

    protein.name: GCN2(Kin.Dom.2,S808G)
  53. PI-103 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1148

    protein.name: GCN2(Kin.Dom.2,S808G)
  54. GSK429286A KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1016

    protein.name: GCN2(Kin.Dom.2,S808G)
  55. Sigma A6730 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1069

    protein.name: GCN2(Kin.Dom.2,S808G)
  56. Buparlisib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1346

    internal.projectName: LINCS phase 2
  57. JW-7-24-1 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1094

    protein.name: JAK1(Kin.Dom.2)
  58. XMD11-85h KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1057

    protein.name: GCN2(Kin.Dom.2,S808G)
  59. CGP082996 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1216

    internal.projectName: LINCS phase 2
  60. A770041 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1099

    protein.name: JAK1(Kin.Dom.2)
  61. XMD8-85 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1062

    protein.name: GCN2(Kin.Dom.2,S808G)
  62. WH-4-025 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1042

    protein.name: GCN2(Kin.Dom.2,S808G)
  63. SP600125 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1097

    protein.name: JAK1(Kin.Dom.2)
  64. BI-2536 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1043

    protein.name: JAK1(Kin.Dom.2)
  65. HG-5-113-01 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1037

    protein.name: JAK1(Kin.Dom.2)
  66. A443654 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1045

    protein.name: JAK1(Kin.Dom.2)
  67. WZ-7043 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1053

    internal.projectName: LINCS phase 2
  68. TGX221 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1214

    internal.projectName: LINCS phase 2
  69. VX-680 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1178

    protein.name: GCN2(Kin.Dom.2,S808G)
  70. PHA-793887 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1111

    protein.name: GCN2(Kin.Dom.2,S808G)
  71. CP-690550 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1169

    protein.name: GCN2(Kin.Dom.2,S808G)
  72. Baricitinib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1217

    internal.projectName: LINCS phase 2
  73. Taselisib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1348

    internal.projectName: LINCS phase 2
  74. MLN8054 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1028

    protein.name: GCN2(Kin.Dom.2,S808G)
  75. AG1478 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1072

    protein.name: GCN2(Kin.Dom.2,S808G)
  76. XMD15-27 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1060

    protein.name: GCN2(Kin.Dom.2,S808G)
  77. AZD7762 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1013

    protein.name: GCN2(Kin.Dom.2,S808G)
  78. Lapatinib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1093

    protein.name: GCN2(Kin.Dom.2,S808G)
  79. AMG-706 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1131

    protein.name: GCN2(Kin.Dom.2,S808G)
  80. NU7441 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1026

    protein.name: GCN2(Kin.Dom.2,S808G)
  81. BIBW-2992 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1153

    protein.name: GCN2(Kin.Dom.2,S808G)
  82. SGX-523 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1146

    protein.name: GCN2(Kin.Dom.2,S808G)
  83. PHA-665752 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1147

    protein.name: GCN2(Kin.Dom.2,S808G)
  84. SB-203580 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1158

    protein.name: GCN2(Kin.Dom.2,S808G)
  85. Sunitinib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1160

    protein.name: GCN2(Kin.Dom.2,S808G)
  86. GDC-0879 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1162

    protein.name: GCN2(Kin.Dom.2,S808G)
  87. HKI-272 KINOMEscan-2 LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1176

  88. HKI-272 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1039

    protein.name: GCN2(Kin.Dom.2,S808G)
  89. AC220 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1128

    protein.name: GCN2(Kin.Dom.2,S808G)
  90. Nilotinib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1143

    protein.name: GCN2(Kin.Dom.2,S808G)
  91. HG-9-91-01 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1118

    protein.name: GCN2(Kin.Dom.2,S808G)
  92. JNK-IN-8 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1350

    internal.projectName: LINCS phase 2
  93. PD0332991 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1030

    protein.name: GCN2(Kin.Dom.2,S808G)
  94. WZ3105 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1054

    protein.name: GCN2(Kin.Dom.2,S808G)
  95. WYE-125132 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1065

    protein.name: GCN2(Kin.Dom.2,S808G)
  96. HG-5-88-01 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1038

    protein.name: JAK1(Kin.Dom.2)
  97. WZ-1-84 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1105

    protein.name: GCN2(Kin.Dom.2,S808G)
  98. PD173074 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1041

    protein.name: GCN2(Kin.Dom.2,S808G)
  99. BEZ235 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1082

    protein.name: GCN2(Kin.Dom.2,S808G)
  100. ALW-II-38-3 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1035

    protein.name: GCN2(Kin.Dom.2,S808G)

Displaying 100 of 190 results for "SIK2"