POU3F1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 59 results for "POU3F1"
i
  1. PO2F3_MOUSE UniProt:Swiss-Prot

    ID: P31362

    Description: POU domain, class 2, transcription factor 3 POU-specific

  2. ETV5 Mediated Downstream Gene Activation in Spermatogonial Stem Cells BioProject

    ID: PRJNA144433

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: tv5), B-cell CLL/lymphoma 6, member B (Bcl6b) and POU domain, class-3 transcription factor-1 (Pou3f1). We reasoned that these three factors may function as a core-set of transcription factors, regulating genes responsible for maintaining the SSC population. Using transient short-interfering RNA oligonucleotides (siRNA) to individually target Etv5, Bcl6b and Pou3f1 within mouse SSC cultures, we examined changes to the global gene expression profiles associated with these transcrip...
  3. Role of Pou3f1 during mouse pluripotent stem cell neural fate commitment ArrayExpress

    ID: E-GEOD-69865

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  4. Genome-wide maps of five major transcription factors in epiblast stem cells BioProject

    ID: PRJNA301044

    Keywords: Epigenomics

    Access Type: download

    dataset.description: ChIP-seq data of ZIC2, OTX2, SOX2, POU5F1 and POU3F1 in EpiSCs Overall design: ChIP-seq using biotinylated transcription factors
  5. Genome-wide maps of five major transcription factors in epiblast stem cells ArrayExpress

    ID: E-GEOD-74636

    Description: ChIP-seq data of ZIC2, OTX2, SOX2, POU5F1 and POU3F1 in EpiSCs ChIP-seq using biotinylated transcription factors

  6. Phrenic neuronal determinants screen in M.Musculus [1] ArrayExpress

    ID: E-GEOD-45807

    Description: n FACS-sorted phrenic cells. Transcription factor Pou3f1 was identified as a major determinant of phrenic identity. Cells type individually compared to the overall expression to identify differentially expressed genes patterns...

  7. Phrenic neuronal determinants screen in M.Musculus [1] BioProject

    ID: PRJNA196414

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. sciP array data BioProject

    ID: PRJNA127479

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. Role of Pou3f1 during mouse pluripotent stem cell neural fate commitment OmicsDI

    ID: E-GEOD-69865

    Date Released: 06-21-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  10. Phrenic neuron determinant gain-of-function screen in M. musculus ES cell-derived motor neurons BioProject

    ID: PRJNA196415

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ssed in FACS-sorted primary. Transcription factor Pou3f1 was identified as a major determinant of phrenic identity. Overall design: Expression in induced cell lines were compared to YFP controls, and over-representation of phrenic genes was computed for the list of differentially expressed genes in each indiced cell lines....
  11. Phrenic neuron determinant gain-of-function screen in M. musculus ES cell-derived motor neurons ArrayExpress

    ID: E-GEOD-45808

    Description: ssed in FACS-sorted primary. Transcription factor Pou3f1 was identified as a major determinant of phrenic identity. Expression in induced cell lines were compared to YFP controls, and over-representation of phrenic genes was computed for the list of differentially expressed genes in each indiced cell lines....

  12. sciP array data ArrayExpress

    ID: E-GEOD-22062

    Description: ted to S-phase. We identify the conserved protein SciP (small CtrA inhibitory protein) and show that it accumulates during G1 where it inhibits CtrA from activating target genes. The depletion of SciP from G1 cells leads to the inappropriate induction of CtrA-activated genes and, consequently, a disruption of the cell cycle. Conversely, the ectopic synthesis of SciP is sufficient to inhibit CtrA-dependent transcription, also disrupting the cell cycle. SciP bi...

  13. Glis3 plays a crucial role in spermatogenesis [848_827] ArrayExpress

    ID: E-GEOD-70194

    Description: ermatogonial cells was significantly decreased in 1-week-old Glis3KO2 testis. These included a set of GDNF-dependent genes, such as Etv5, Bcl6b, Lhx1, Brachyury, Id4, and Pou3f1, and GDNF-independent genes, such as FoxO1, Oct4, and Zbtb16. Impairment of the nuclear localization of FoxO1 may be in part responsible for the reduced expression of Ret, Lhx1, and Sall4 in Glis3KO2 testis. Our study identifies Glis3 as a novel and critical regulator of early stages of spermatogenesis. Testis total RNAs were purified from 4 WT and 4 Glis3KO2 at 1 week old age, and 3WT and 3 Glis3KO2 at 3 week-old age. Then the samples were applied to Agilent mouse genome chip....

  14. Oct6 promotes neural commitment via activation of neural lineage genes and inhibition of BMP/Wnt signals OmicsDI

    ID: E-GEOD-54569

    Date Released: 05-30-2014

    Description: appropriate neural conversion. Here, we show that Oct6 functions as an essential positive factor for neural differentiation of mouse embryonic stem cells (ESCs), specifically during the transition from epiblast stem cells (EpiSCs) to neural progenitor cells (NPCs). Chimera analysis showed that Oct6 knockdown leads to markedly decreased incorporation of ESC in neuroectoderm. By contrast,

  15. Glis3 plays a crucial role in spermatogenesis [923] ArrayExpress

    ID: E-GEOD-70195

    Description: ermatogonial cells was significantly decreased in 1-week-old Glis3KO2 testis. These included a set of GDNF-dependent genes, such as Etv5, Bcl6b, Lhx1, Brachyury, Id4, and Pou3f1, and GDNF-independent genes, such as FoxO1, Oct4, and Zbtb16. Impairment of the nuclear localization of FoxO1 may be in part responsible for the reduced expression of Ret, Lhx1, and Sall4 in Glis3KO2 testis. Our study identifies Glis3 as a novel and critical regulator of early stages of spermatogenesis. Thy1+ cells were isolated from 3 WT and 3 Glis3KO2 testis at postnatal day 4, and total RNAs were purified from them. Then the samples were applied to Agilent mouse genome chip....

  16. Oct6 promotes neural commitment via activation of neural lineage genes and inhibition of BMP/Wnt signals ArrayExpress

    ID: E-GEOD-54569

    Description: appropriate neural conversion. Here, we show that Oct6 functions as an essential positive factor for neural differentiation of mouse embryonic stem cells (ESCs), specifically during the transition from epiblast stem cells (EpiSCs) to neural progenitor cells (NPCs). Chimera analysis showed that Oct6 knockdown leads to markedly decreased incorporation of ESC in neuroectoderm. By contrast,

  17. sciP array data OmicsDI

    ID: E-GEOD-22062

    Date Released: 05-02-2014

    Description: ted to S-phase. We identify the conserved protein SciP (small CtrA inhibitory protein) and show that it accumulates during G1 where it inhibits CtrA from activating target genes. The depletion of SciP from G1 cells leads to the inappropriate induction of CtrA-activated genes and, consequently, a disruption of the cell cycle. Conversely, the ectopic synthesis of SciP is sufficient to inhibit CtrA-dependent transcription, also disrupting the cell cycle. SciP bi...

  18. Phrenic neuronal determinants screen in M.Musculus [1] OmicsDI

    ID: E-GEOD-45807

    Date Released: 06-03-2014

    Description: n FACS-sorted phrenic cells. Transcription factor Pou3f1 was identified as a major determinant of phrenic identity. Cells type individually compared to the overall expression to identify differentially expressed genes patterns...

  19. Converting Oct6 into a pluripotency inducer by interrogating Oct4 residues BioProject

    ID: PRJNA323374

    Keywords: Transcriptome or Gene expression

    Access Type: download

  20. Glis3 plays a crucial role in spermatogenesis [848_827] BioProject

    ID: PRJNA287834

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ermatogonial cells was significantly decreased in 1-week-old Glis3KO2 testis. These included a set of GDNF-dependent genes, such as Etv5, Bcl6b, Lhx1, Brachyury, Id4, and Pou3f1, and GDNF-independent genes, such as FoxO1, Oct4, and Zbtb16. Impairment of the nuclear localization of FoxO1 may be in part responsible for the reduced expression of Ret, Lhx1, and Sall4 in Glis3KO2 testis. Our study identifies Glis3 as a novel and critical regulator of early stages of spermatogenesis. Overall design: Testis total RNAs were purified from 4 WT and 4 Glis3KO2 at 1 week old age, and 3WT and 3 Glis3KO2 at 3 week-old age. Then the samples were applied to Agilent mouse genome chip....

Displaying 20 of 59 results for "POU3F1"