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Displaying 10 of 59 results for "POU3F1"
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  1. The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways BioProject

    ID: PRJNA237042

    Keywords: Other

    Access Type: download

  2. CRYSTAL STRUCTURE OF THE DIMERIC OCT-6 (POU3F1) POU DOMAIN BOUND TO PALINDROMIC MORE DNA PDB

    ID: PDB:2XSD

    Description: POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 1/DNA Complex, 1,2-ETHANEDIOL

  3. Data from: The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways... Dryad

    DateIssued: 07-16-2014

    Description: conversion remains unclear. Here, we showed that Pou3f1 is essential for the neural differentiation of mouse embryonic stem cells (ESCs), specifically during the transition from epiblast stem cells (EpiSCs) to neural progenitor cells (NPCs). Chimeric analysis showed that Pou3f1 knockdown leads to a markedly decreased incorporation of ESCs in the neuroectoderm. By contrast, Pou3f1-overe...

  4. ETV5 Mediated Downstream Gene Activation in Spermatogonial Stem Cells ArrayExpress

    ID: E-GEOD-30683

    Description: tv5), B-cell CLL/lymphoma 6, member B (Bcl6b) and POU domain, class-3 transcription factor-1 (Pou3f1). We reasoned that these three factors may function as a core-set of transcription factors, regulating genes responsible for maintaining the SSC population. Using transient short-interfering RNA oligonucleotides (siRNA) to individually target Etv5, Bcl6b and Pou3f1 within mouse SSC cultures, we examined changes to the global gene expression profiles associated with these transcrip...

  5. Genome-wide ChIP-seq analysis of Pou3f1 during mouse pluripotent stem cell neural fate commitment BioProject

    ID: PRJNA286774

    Keywords: Epigenomics

    Access Type: download

  6. ETV5 Mediated Downstream Gene Activation in Spermatogonial Stem Cells OmicsDI

    ID: E-GEOD-30683

    Date Released: 08-02-2011

    Description: tv5), B-cell CLL/lymphoma 6, member B (Bcl6b) and POU domain, class-3 transcription factor-1 (Pou3f1). We reasoned that these three factors may function as a core-set of transcription factors, regulating genes responsible for maintaining the SSC population. Using transient short-interfering RNA oligonucleotides (siRNA) to individually target Etv5, Bcl6b and Pou3f1 within mouse SSC cultures, we examined changes to the global gene expression profiles associated with these transcrip...

  7. PO3F2_RAT UniProt:Swiss-Prot

    ID: P56222

    Description: POU domain, class 3, transcription factor 2 POU-specific

  8. Genome-wide ChIP-seq analysis of Pou3f1 during mouse pluripotent stem cell neural fate commitment ArrayExpress

    ID: E-GEOD-69778

    Description: s, we demonstrate that the transcriptional factor Pou3f1 is an upstream activator of neural-promoting genes, and it is able to repress neural-inhibitory signals as well. Further studies revealed that Pou3f1 could directly bind neural lineage genes like Sox2 and downstream targets of neural inhibition signaling such as BMP and Wnt. Our results thus identify Pou3f1 as a critical dual-regulator of the intrinsic transcription factors and the extrinsic cellular signals during neural fate commitment. ChIP-seq assay was ultilized to characterize the targets of Pou3f1

  9. PO3F3_MOUSE UniProt:Swiss-Prot

    ID: P31361

    Description: POU domain, class 3, transcription factor 3 POU-specifi...

  10. PO3F3_XENLA UniProt:Swiss-Prot

    ID: P20914

    Description: POU domain, class 3, transcription factor 3 POU-specifi...


Displaying 10 of 59 results for "POU3F1"