PCSK1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 609 results for "PCSK1"
i
  1. AGRP_BOVIN UniProt:Swiss-Prot

    ID: P56413

    Description: Agouti-related protein Agouti Interaction with melanocortin receptors Cleavage; by PCSK1

  2. AGRP_PIG UniProt:Swiss-Prot

    ID: Q9TU18

    Description: Agouti-related protein Agouti Interaction with melanocortin receptors Cleavage; by PCSK1

  3. SPXN_DANRE UniProt:Swiss-Prot

    ID: F1QQI2

    Description: Spexin Spexin-1 Cleavage; by prohormone convertase 2 Glutamine amide

  4. Gene expression profile of adipocytes treated with bisphenol A or 17beta-estradiol OmicsDI

    ID: E-GEOD-58516

    Date Released: 09-18-2015

    Description: n adipocytes culture medium, and insulin, in PANC-1 culture medium, were performed using ELISA assays. BPA was found to promote up-regulation of ERα and ERRγ, and down-regulation of GPR30 expression modulating estrogen signaling and following a non-linear dose-response. Microarray data analysis demonstrated that BPA increases the gene expression of pro-inflammatory cytokines and lipid metabolism-related FABP4 and CD36 in adipocytes. PCSK1 resulted the most interesting gene being down-regulated by BPA thus impairing insulin production in pancreas. BPA promotes inflammation and lipid metabolism dysregulation in adipocytes from lean children. Moreover, PCSK1 can be a key gene in BPA action modulating insulin production. Exposure to BPA in childhood may be an important risk factor in developing obesity and metabolic disorders. Three prototypic situations were analyzed (5 replication each): untreated cells (C), 10 nM BPA treated cells (BPA), 1 nM 17-beta Estradiol treated cells (ES)....

  5. Bacillus sp. Pc3 : Bacillus sp. Pc3 Genome sequencing BioProject

    ID: PRJNA271045

    Keywords: Genome sequencing

    Access Type: download

  6. ERG Overexpression in PC3 cells. BioProject

    ID: PRJNA140405

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. GLUC_CARAU UniProt:Swiss-Prot

    ID: P79695

    Description: Glicentin-related polypeptide Glucagon Glucagon-like peptide Cleavage; by PCSK2 Cleavage; by PCSK1

  8. Microarray analysis of PC3 prostate tumor-initiating cells (PC3 holoclones) BioProject

    ID: PRJNA227068

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. miR-145 transfected PC3 cells BioProject

    ID: PRJNA251942

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. Effects of bisphenol A on gene expression in adipocytes from lean children: association to metabolic disorders BioProject

    ID: PRJNA252814

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: n adipocytes culture medium, and insulin, in PANC-1 culture medium, were performed using ELISA assays. BPA was found to promote up-regulation of ERα and ERRγ, and down-regulation of GPR30 expression modulating estrogen signaling and following a non-linear dose-response. Microarray data analysis demonstrated that BPA increases the gene expression of pro-inflammatory cytokines and lipid metabolism-related FABP4 and CD36 in adipocytes. PCSK1 resulted the most interesting gene being down-regulated by BPA thus impairing insulin production in pancreas. BPA promotes inflammation and lipid metabolism dysregulation in adipocytes from lean children. Moreover, PCSK1 can be a key gene in BPA action modulating insulin production. Exposure to BPA in childhood may be an important risk factor in developing obesity and metabolic disorders. Overall design: Three prototypic situations were analyzed (5 replication each): untreated cells (C), 10 nM BPA treated cells (BPA), 1 nM 17-β Estradiol treat...
  11. ASNase treatment in PC3 cells BioProject

    ID: PRJNA300627

    Keywords: Other

    Access Type: download

  12. Effect of U94 in Gene Expression in PC3 Cells BioProject

    ID: PRJNA90537

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. PC3 cells transfected with androgen receptor treated with various concentration of androgens BioProject

    ID: PRJNA114795

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. The network of genes regulated by Ago1 in metastatic prostate cancer PC3 BioProject

    ID: PRJNA248343

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. PC3 vs LNCaP amplified and unamplified miRNA BioProject

    ID: PRJNA94407

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. Data from: Sexual selection and experimental evolution of chemical signals in Drosophila pseudoobscura Dryad

    DateIssued: 11-06-2012

    Description: ent analysis that explained 72% of the variation. PC1 described the amount of CHs produced, PC2 the trade-off between short- and long-chain CHs and PC3 the trade-off between apparently arbitrary CHs. In both sexes, the amount of CHs produced was greater in flies from the E treatment. PC3 was also higher, indicating that sexual selection also influenced the evolution of CH composition. The sexes differed in all three PCs indicating substantial sexual dimorphism in this species, although the magnitude of this dimorphism was not increased as a result of our experimental evolution. Collectively, our work provides direct evidence that sexual selection plays an important role in the evolution of ...

  17. Microarray analysis of PC3 prostate tumor-initiating cells (PC3 holoclones) OmicsDI

    ID: E-GEOD-52161

    Date Released: 06-03-2014

    Description: rogen-independent human prostate cancer cell line PC3. RESULTS: We demonstrate that, under standard culture conditions, ~10% of PC3 cells form holoclones with cancer stem cell characteristics. These holoclones display high self-renewal capability in spheroid formation assays under low attachment and serum-free culture conditions, retain their holoclone morphology when passaged at high cell density, exhibit moderate drug resistance, and show high tumorigenicity in scid immunodeficient mice. PC3 holoclones readily form spheres, and PC3-derived spheres yield a high p...

  18. Microarray analysis of PC3 prostate tumor-initiating cells (PC3 holoclones) ArrayExpress

    ID: E-GEOD-52161

    Description: rogen-independent human prostate cancer cell line PC3. RESULTS: We demonstrate that, under standard culture conditions, ~10% of PC3 cells form holoclones with cancer stem cell characteristics. These holoclones display high self-renewal capability in spheroid formation assays under low attachment and serum-free culture conditions, retain their holoclone morphology when passaged at high cell density, exhibit moderate drug resistance, and show high tumorigenicity in scid immunodeficient mice. PC3 holoclones readily form spheres, and PC3-derived spheres yield a high p...

  19. PRIDE PXD001075 - Identification of biomarkers for PKD1 using urinary exosomes OmicsDI

    ID: MSV000079547

    Date Released:

    Description: D1 or PKD2 gene, encoding the proteins polycystin?1 (PC1) or polycystin?2 (PC2) respectively. PC1 and PC2 are secreted on urinary exosome?like vesicles (ELVs) (100nm diameter vesicles), where PC1 is present in a cleaved form and may be complexed with PC2. Label free...

  20. Gene expression profiling of the prostate cancer cell line PC3. BioProject

    ID: PRJNA319927

    Keywords: Transcriptome or Gene expression

    Access Type: download


Displaying 20 of 609 results for "PCSK1"