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Displaying 20 of 140 results for "NRIP3"
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  1. Co-activator function of RIP140 for NFκB/p65-dependent cytokine gene ArrayExpress

    ID: E-GEOD-10386

    Description: e describe an unexpected co-activator function of receptor interacting protein (RIP) 140 for nuclear factor (NF) kB, a master transcriptional regulator of inflammation in multiple tissues. Genetic as well as acute deficiency of RIP140, which has been characterized as a co-repressor of various

  2. The role of RIP140 in retinoid mediated signaling BioProject

    ID: PRJNA100483

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Cell-and context-specific activities of nuclear receptors may in part be due to distinct coregulator complexes recruited to distinct subsets of target genes. RIP140 (als...
  3. Rictor Plays a Pivotal Role in Maintaining Quiescence as well as Stemness of Leukemia Stem Cells in MLL-Driven Leukemia OmicsDI

    ID: E-GEOD-84505

    Date Released: 07-23-2016

    Description: is on Affymetrix microarrays.Furthermore, the MLL-NRIP3-driven mice model was chosen for further examination.The K+G– mice BM cells were sorted from the 1st BMT of RictorΔ/Δ(MN3_R1,MN3_R2,MN3_R3) or control(MN3_C1,MN3_C2,MN3_C3), and subjected to microarray analysis on Affymetrix microarrays....

  4. Co-activator function of RIP140 for NF?B/p65-dependent cytokine gene BioProject

    ID: PRJNA108129

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: e describe an unexpected co-activator function of receptor interacting protein (RIP) 140 for nuclear factor (NF) kB, a master transcriptional regulator of inflammation in multiple tissues. Genetic as well as acute deficiency of RIP140, which has been characterized as a co-repressor of various
  5. Transcription profiling of mouse adipocytes to determine the role of RIP140 in adipocyte differentiation ArrayExpress

    ID: E-MIMR-42

    Description: Title: Gene Expression analysis of the role of RIP140 in adipocyte differentiation Description: RIPKO cells are mouse embryo fibroblasts (MEF) that we...

  6. Analysis of HER2 genomic binding in breast cancer cells identifies a global role in direct gene regulation [ChIP-exo] BioProject

    ID: PRJNA316983

    Keywords: Epigenomics

    Access Type: download

    dataset.description: HER2 is a transmembrane receptor tyrosine kinase, which plays a key role in breast cancer due to a common genomic amplification. It is used as a marker to ...
  7. Analysis of HER2 genomic binding in breast cancer cells identifies a global role in direct gene regulation [RNA-Seq] BioProject

    ID: PRJNA316984

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: HER2 is a transmembrane receptor tyrosine kinase, which plays a key role in breast cancer due to a common genomic amplification. It is used as a marker to ...
  8. Differential gene expression between human Cord blood transduced with HPIP-wt, mutant NRPID and control YFP BioProject

    ID: PRJNA121571

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: development. Previously, the ‘hematopoietic PBX interacting protein’ (HPIP) has been identified as a novel interacting partner of the TALE homeodomain protein PBX1, forming a microtubule signalling complex. Expression of HPIP has b...
  9. Nuclear receptor coactivator 1 (NCOA1) is involved in the regulation of PCa cell migration via PRKD1 BioProject

    ID: PRJNA304492

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. Brain transcriptomic response to social eavesdropping in zebrafish BioProject

    ID: PRJNA286322

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ing data from both approaches, we further drafted protein interaction networks. Our results suggest that attentiveness towards conspecifics, whether interacting or not, activates pathways linked to neuronal plasticity and memory formation. The network analyses suggested that fos and jun are key players on this response, and that npas4a, nr4a1 and egr4 may also play an important role. Furthermore, specifically observing fighting interactions further triggered pathways associated to a change in the alertness status (dnajb5) and to other genes related to memory formation (btg2, npas4b), which suggests that the acquisition of eavesdropped information about social relationships activates specific processes on top of those already activated just by observing conspecifics. Overall design: 39 fish were previously subjected to one of three treatments (13 individuals per group) for 30 minutes: bystander to an interacting male conspecific dyad; bystander to two non-interacting male conspecifics; and socially isolated fish. From these, 4 representati...
  11. siRNA knock down of RIP140 in the presence of retinoic acid vs controls to investigate the role of RIP140 in retinoid mediated signaling ArrayExpress

    ID: E-GEOD-7500

    Description: Cell-and context-specific activities of nuclear receptors may in part be due to distinct coregulator complexes recruited to distinct subsets of target genes. RIP140 (als...

  12. Nuclear receptor coactivator 1 (NCOA1) is involved in the regulation of PCa cell migration via PRKD1 ArrayExpress

    ID: E-GEOD-75531

    Description: rgent need of new targeting strategies in PCa, AR interacting proteins should be considered. In this study we aimed to test the effect of a long-term knockdown of NCOA1, an AR coactivator, in P...

  13. Rictor Plays a Pivotal Role in Maintaining Quiescence as well as Stemness of Leukemia Stem Cells in MLL-Driven Leukemia BioProject

    ID: PRJNA329510

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: is on Affymetrix microarrays.Furthermore, the MLL-NRIP3-driven mice model was chosen for further examination.The K+G– mice BM cells were sorted from the 1st BMT of RictorΔ/Δ(MN3_R1,MN3_R2,MN3_R3) or control(MN3_C1,MN3_C2,MN3_C3), and subjected to microarray analysis on Affymetrix microarrays....
  14. Differential gene expression between human Cord blood transduced with HPIP-wt, mutant NRPID and control YFP ArrayExpress

    ID: E-GEOD-18640

    Description: development. Previously, the ‘hematopoietic PBX interacting protein’ (HPIP) has been identified as a novel interacting partner of the TALE homeodomain protein PBX1, forming a microtubule signalling complex. Expression of HPIP has b...

  15. Nuclear receptor coactivator 1 (NCOA1) is involved in the regulation of PCa cell migration via PRKD1 OmicsDI

    ID: E-GEOD-75531

    Date Released: 06-26-2016

    Description: rgent need of new targeting strategies in PCa, AR interacting proteins should be considered. In this study we aimed to test the effect of a long-term knockdown of NCOA1, an AR coactivator, in P...

  16. Differential gene expression between human Cord blood transduced with HPIP-wt, mutant NRPID and control YFP OmicsDI

    ID: E-GEOD-18640

    Date Released: 06-10-2011

    Description: development. Previously, the ‘hematopoietic PBX interacting protein’ (HPIP) has been identified as a novel interacting partner of the TALE homeodomain protein PBX1, forming a microtubule signalling complex. Expression of HPIP has b...

  17. Analysis of the receptor-interacting protein-140 (RIP140/Nrip1)-dependent transcriptome in the mouse adipogenic program NURSA

    Keywords: WAT adipocytes MEF-derived

    Description: The RIPKO-L16 mouse embryonic fibroblast cell line was generated using lentiviral transduction of RIP140/Nrip1 KO MEFs with a RIP140/Nrip1 expression ...

    ID: 10.1621/WugGwn4VIV

  18. 292 Retina

    Biological Entity: Amacrine cell, Cells in ganglion cell layer

    Molecular Entity: Nrip3

  19. Transcriptional regulatory dynamics set the stage for a coordinated metabolic and neural response to social threat in mice. [ChIP-Seq data set] BioProject

    ID: PRJNA320640

    Keywords: Epigenomics

    Access Type: download

    dataset.description: regulatory network and motif analyses revealed an interacting network of TFs correlated with differential gene expression across the tissues and time points we assayed, including the early-acting and conserved regulator of energy metabolism and development, ESRRA. Cell-type deconvolution analysis attributed the early metabolic activity implicated by our transcriptomic analysis primarily to oligodendrocytes and the developmental signal to neurons, and we confirmed the presence of ESRRA in both oligodendrocytes and neurons throughout the brain. To assess the role of this nuclear receptor as an early trigger of this coordinated response, we used chromatin immunoprecipitation to map ESRRA binding sites to a set of genes involved in metabolic regulation and enriched in challenge-associated differentially expressed genes. Together, these data support a rich model linking metabolic and neural responses to social challenge, and identify regulatory drivers with unprecedented tissue and...
  20. Transcriptional regulatory dynamics set the stage for a coordinated metabolic and neural response to social threat in mice [RNA-Seq data set] BioProject

    ID: PRJNA318643

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: regulatory network and motif analyses revealed an interacting network of TFs correlated with differential gene expression across the tissues and time points we assayed, including the early-acting and conserved regulator of energy metabolism and development, ESRRA. Cell-type deconvolution analysis attributed the early metabolic activity implicated by our transcriptomic analysis primarily to oligodendrocytes and the developmental signal to neurons, and we confirmed the presence of ESRRA in both oligodendrocytes and neurons throughout the brain. To assess the role of this nuclear receptor as an early trigger of this coordinated response, we used chromatin immunoprecipitation to map ESRRA binding sites to a set of genes involved in metabolic regulation and enriched in challenge-associated differentially expressed genes. Together, these data support a rich model linking metabolic and neural responses to social challenge, and identify regulatory drivers with unprecedented tissue and...

Displaying 20 of 140 results for "NRIP3"