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Displaying 20 of 184 results for "NLK"
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  1. TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma OmicsDI

    ID: E-GEOD-15264

    Date Released: 03-27-2012

    Description: ation of multiple receptors activates the IkappaB kinase (IKK) complex that phosphorylates IkappaB at two specific serine residues, followed by its ubiquitination and proteasomal degradation, thereby releasing NF-kappaB proteins and allowing their nuclear translocation (3). Recently, two studies provided further insights into the molecular mechanisms of IKK activation upon TNF stimulation (4, 5). Activation of the IKK complex and subsequent NF-kappaB activation requires Lys63 polyubiquitination of RIP1, a kinase which is recruited to the receptor upon TNF stimulation. IKK-(NEMO), the regulatory subunit of the IKK complex, specifically recognizes these Lys63-linked polyubiquitins attached to RIP1 and thereby activates IKK and NF-kappaB (4, 5...

  2. BMS-536924 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1098

    protein.name: NLK
  3. ALW-II-49-7 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1036

    protein.name: NLK
  4. GDC-0941 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1046

    protein.name: NLK
  5. NVP-TAE684 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1095

    protein.name: NLK
  6. KIN001-127 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1044

    protein.name: NLK
  7. CGP60474 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1040

    protein.name: NLK
  8. CI-1033 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1104

    protein.name: NLK
  9. WZ4002 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1055

    protein.name: NLK
  10. LY-317615 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1140

    protein.name: NLK
  11. Gefitinib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1142

    protein.name: NLK
  12. HG-14-10-04 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1120

    protein.name: NLK
  13. ABT-869 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1163

    protein.name: NLK
  14. INCB018424 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1154

    protein.name: NLK
  15. VX-745 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1159

    protein.name: NLK
  16. AT-7519 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1172

    protein.name: NLK
  17. GW843682 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1018

    protein.name: NLK
  18. CEP-701 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1170

    protein.name: NLK
  19. Dabrafenib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1117

    protein.name: NLK
  20. ZM-447439 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1033

    protein.name: NLK

Displaying 20 of 184 results for "NLK"