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Displaying 50 of 184 results for "NLK"
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  1. NLK_BOVIN UniProt:Swiss-Prot

    ID: E1BMN8

    Description: Serine/threonine-protein kinase NLK Protein kinase ATP Required for interaction with TAB2 Sufficient for interaction w...

  2. Neuron-specific deletion of the miRNA-processing enzyme DICER induces severe but transient obesity in mice BioProject

    ID: PRJNA262716

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ated pathways including leptin, somatostatin, and nemo-like kinase signaling, as well as genes involved in feeding and appetite (e.g. Pmch, Neurotensin). A cluster of genes involved in synaptic plasticity was specifically enriched in post-obese mice that did not appear in obese mice. While other studies have identified a role for miRNAs in obesity our model is unique in that it allows for the study of processes involved in reversing obesity. Overall design: Tissues were collected 4 weeks and 8 weeks after induction of dicer gene knock-out. For each tissue (i.e., cortex, hypothalamus, hippocampus) a total of 3 animals per treatment and per time point was used. Genetic modification....
  3. LEF1_RAT UniProt:Swiss-Prot

    ID: Q9QXN1

    Description: -rich Poly-Lys Phosphoserine Phosphothreonine; by NLK Phosphoserine; by NLK Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)...

  4. LEF1_MOUSE UniProt:Swiss-Prot

    ID: P27782

    Description: -rich Poly-Lys Phosphoserine Phosphothreonine; by NLK Phosphoserine; by NLK Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) In isoform 2. Strongly diminishes CTNNB1 b...

  5. NLK_CAEBR UniProt:Swiss-Prot

    ID: A8XSC1

    Description: Serine/threonine kinase NLK Protein kinase ATP Gln-rich His-rich Proton acceptor ATP

  6. STAT3_RAT UniProt:Swiss-Prot

    ID: P52631

    Description: nd PTK6 Phosphothreonine Phosphoserine; by DYRK2, NLK, NEK6, IRAK1, RPS6KA5, ZIPK/DAPK3 and PKC/PRKCE...

  7. STA32_XENLA UniProt:Swiss-Prot

    ID: Q7ZXK3

    Description: Signal transducer and activator of transcription 3.2 SH2 Essential for nuclear import Phosphoserine; by NLK

  8. NLK2_XENTR UniProt:Swiss-Prot

    ID: B1H3E1

    Description: Serine/threonine-protein kinase NLK2 Protein kinase ATP Poly-Gly Proton acceptor ATP

  9. FOXO1_RAT UniProt:Swiss-Prot

    ID: G3V7R4

    Description: nding DNA binding Sufficient for interaction with NLK Required for interaction with RUNX2 Nuclear localization signal Required for interaction with SIRT1 Poly-Ala Pro-rich DNA binding DNA binding DNA binding Phosphothreon...

  10. FOXO1_PIG UniProt:Swiss-Prot

    ID: A4L7N3

    Description: nding DNA binding Sufficient for interaction with NLK Required for interaction with RUNX2 Nuclear localization signal Required for interaction with SIRT1 Ala-rich Pro-rich Poly-Ser DNA binding DNA binding DNA binding Phos...

  11. STA31_XENLA UniProt:Swiss-Prot

    ID: Q9PVX8

    Description: H2 Essential for nuclear import Phosphoserine; by NLK Does not induce t/bra expression; when associated A-728. Induces t/bra expression; when associated with E-728 Inhibits t/bra expression and mesoderm induction Inhibits t/bra express...

  12. MYB_BOVIN UniProt:Swiss-Prot

    ID: P46200

    Description: -T-H motif H-T-H motif Interaction with HIPK2 and NLK Transcriptional activation domain Negative regulatory domain Leucine-zipper N6-acetyllysine N6-acetyllysine Phosphoserine Phosphothreonine...

  13. FOXO1_ICTTR UniProt:Swiss-Prot

    ID: Q810W5

    Description: nding DNA-binding Sufficient for interaction with NLK Required for interaction with RUNX2 Nuclear localization signal Required for interaction with SIRT1 Poly-Ala DNA-binding DNA-binding DNA-binding Phosphothreonine; by P...

  14. STAT3_BOVIN UniProt:Swiss-Prot

    ID: P61635

    Description: nd PTK6 Phosphothreonine Phosphoserine; by DYRK2, NLK, NEK6, IRAK1, RPS6KA5, ZIPK/DAPK3 and PKC/PRKCE...

  15. STAT3_PIG UniProt:Swiss-Prot

    ID: Q19S50

    Description: nd PTK6 Phosphothreonine Phosphoserine; by DYRK2, NLK, NEK6, IRAK1, RPS6KA5, ZIPK/DAPK3 and PKC/PRKCE...

  16. FOXO1_BOVIN UniProt:Swiss-Prot

    ID: E1BPQ1

    Description: nding DNA binding Sufficient for interaction with NLK Required for interaction with RUNX2 Nuclear localization signal Required for interaction with SIRT1 Ala-rich Poly-Ser DNA binding DNA binding DNA binding Phosphothreon...

  17. TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma ArrayExpress

    ID: E-GEOD-15264

    Description: ation of multiple receptors activates the IkappaB kinase (IKK) complex that phosphorylates IkappaB at two specific serine residues, followed by its ubiquitination and proteasomal degradation, thereby releasing NF-kappaB proteins and allowing their nuclear translocation (3). Recently, two studies provided further insights into the molecular mechanisms of IKK activation upon TNF stimulation (4, 5). Activation of the IKK complex and subsequent NF-kappaB activation requires Lys63 polyubiquitination of RIP1, a kinase which is recruited to the receptor upon TNF stimulation. IKK-(NEMO), the regulatory subunit of the IKK complex, specifically recognizes these Lys63-linked polyubiquitins attached to RIP1 and thereby activates IKK and NF-kappaB (4, 5...

  18. NLK_RAT UniProt:Swiss-Prot

    ID: D3ZSZ3

    Description: Serine/threonine-protein kinase NLK Protein kinase ATP Required for interaction with TAB2 Sufficient for interaction w...

  19. NLK_CANLF UniProt:Swiss-Prot

    ID: E2QWQ2

    Description: Serine/threonine-protein kinase NLK Protein kinase ATP Required for interaction with TAB2 Sufficient for interaction w...

  20. TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma BioProject

    ID: PRJNA116491

    Keywords: Variation

    Access Type: download

    dataset.description: ation of multiple receptors activates the IkappaB kinase (IKK) complex that phosphorylates IkappaB at two specific serine residues, followed by its ubiquitination and proteasomal degradation, thereby releasing NF-kappaB proteins and allowing their nuclear translocation (3). Recently, two studies provided further insights into the molecular mechanisms of IKK activation upon TNF stimulation (4, 5). Activation of the IKK complex and subsequent NF-kappaB activation requires Lys63 polyubiquitination of RIP1, a kinase which is recruited to the receptor upon TNF stimulation. IKK-gamma (NEMO), the regulatory subunit of the IKK complex, specifically recognizes these Lys63-linked polyubiquitins attached to RIP1 and thereby activates IKK and NF-kappaB (4, 5...
  21. TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma OmicsDI

    ID: E-GEOD-15264

    Date Released: 03-27-2012

    Description: ation of multiple receptors activates the IkappaB kinase (IKK) complex that phosphorylates IkappaB at two specific serine residues, followed by its ubiquitination and proteasomal degradation, thereby releasing NF-kappaB proteins and allowing their nuclear translocation (3). Recently, two studies provided further insights into the molecular mechanisms of IKK activation upon TNF stimulation (4, 5). Activation of the IKK complex and subsequent NF-kappaB activation requires Lys63 polyubiquitination of RIP1, a kinase which is recruited to the receptor upon TNF stimulation. IKK-(NEMO), the regulatory subunit of the IKK complex, specifically recognizes these Lys63-linked polyubiquitins attached to RIP1 and thereby activates IKK and NF-kappaB (4, 5...

  22. BMS-536924 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1098

    protein.name: NLK
  23. ALW-II-49-7 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1036

    protein.name: NLK
  24. GDC-0941 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1046

    protein.name: NLK
  25. NVP-TAE684 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1095

    protein.name: NLK
  26. KIN001-127 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1044

    protein.name: NLK
  27. CGP60474 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1040

    protein.name: NLK
  28. CI-1033 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1104

    protein.name: NLK
  29. WZ4002 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1055

    protein.name: NLK
  30. LY-317615 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1140

    protein.name: NLK
  31. Gefitinib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1142

    protein.name: NLK
  32. HG-14-10-04 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1120

    protein.name: NLK
  33. ABT-869 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1163

    protein.name: NLK
  34. INCB018424 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1154

    protein.name: NLK
  35. VX-745 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1159

    protein.name: NLK
  36. AT-7519 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1172

    protein.name: NLK
  37. GW843682 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1018

    protein.name: NLK
  38. CEP-701 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1170

    protein.name: NLK
  39. Dabrafenib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1117

    protein.name: NLK
  40. ZM-447439 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1033

    protein.name: NLK
  41. TG-101348 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1155

    protein.name: NLK
  42. XMD11-50 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1056

    protein.name: NLK
  43. GW-5074 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1008

    protein.name: NLK
  44. CP724714 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1015

    protein.name: NLK
  45. JNK-IN-5A KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1067

    protein.name: NLK
  46. AZD-6244 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1137

    protein.name: NLK
  47. PI-103 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1148

    protein.name: NLK
  48. GSK429286A KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1016

    protein.name: NLK
  49. Sigma A6730 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1069

    protein.name: NLK
  50. Buparlisib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1346

    protein.name: NLK

Displaying 50 of 184 results for "NLK"