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Displaying 10 of 14 results for "NFKBIE"
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  1. Analysis of differential gene expression in NFKBIE-mutated and non-mutated primary mediastinal B-cell lymphoma (PMBL) ... BioProject

    ID: PRJNA342614

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. RNA-sequencing of human B cells to investigate chronic lymphocytic leukemia mutations observed in hematopoietic multipotent progenitor fractions ArrayExpress

    ID: E-MTAB-1776

    Description: ern countries, is a clonal accumulation of mature B-lymphocytes and its natural history is yet unclear. By using sequencing and cellular biology approaches on a cohort of CLL patient samples, we show here that acquired CLL mutations are observed in hematopo...

  3. y of mouse EML cell line transfected with EGR2 wt gene, 2 mutated forms (E356K and H384N) and controls with an empty vector... ArrayExpress

    ID: E-MTAB-1764

    Description: ern countries, is a clonal accumulation of mature B-lymphocytes and its natural history is yet unclear. By using sequencing and cellular biology approaches on a cohort of CLL patient samples, we show here that acquired CLL mutations are observed in hematopo...

  4. DNA-seq of exome sequences from tumor cells and T-lymphocytes in 24 chronic lymphocytic leukemia patients to predict somatic mutations in 24 CLL patients (17 IGHV-unmuta... ArrayExpress

    ID: E-MTAB-1775

    Description: ern countries, is a clonal accumulation of mature B-lymphocytes and its natural history is yet unclear. By using sequencing and cellular biology approaches on a cohort of CLL patient samples, we show here that acquired CLL mutations are observed in hematopo...

  5. IGR_U985_RNASeq BioProject

    ID: PRJEB4498

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Homo sapiens : Genetic analysis of desmoplastic melanoma BioProject

    ID: PRJNA293389

    Access Type: download

    dataset.description: tions included recurrent promoter mutations of NF-kappa B inhibitor epsilon, NFKBIE (IkB epsilon) in 14.5% of samples. Commonly mutated oncogenes in melanomas, in particular BRAF(V600E) and NRAS(Q61K/R), were absent. Instead, other genetic alterations known to activate the MAPK and PI3K signaling cascades were identified in 73% of samples, affecting NF1, CBL, ERBB2, MAP2K1, MAP3K1, BRAF, EGFR, PTPN11, MET... (for more see dbGaP study page.)...
  7. IGR_U985_CLL_Exome BioProject

    ID: PRJEB4358

    Keywords: Other

    Access Type: download

    dataset.description: ern countries, is a clonal accumulation of mature B-lymphocytes and its natural history is yet unclear. By using sequencing and cellular biology approaches on a cohort of CLL patient samples, we show here that acquired CLL mutations are observed in hematopo...
  8. WES Hodgkin Lymphoma cell lines : The mutational landscape of Hodgkin lymphoma cell lines determined by whole exome sequencing BioProject

    ID: PRJEB5699

    Keywords: Other

    Access Type: download

    dataset.description: n lymphoma (HL) is characterized by a minority of B cell derived tumor cells, named Hodgkin Reed-Sternberg (HRS) cells in classical (c)HL and lymphoc...
  9. Genetic analysis of desmoplastic melanoma BioProject

    ID: PRJNA293390

    Keywords: Phenotype or Genotype

    Access Type: download

    dataset.description: tions included recurrent promoter mutations of NF-kappa B inhibitor epsilon, NFKBIE (IkB epsilon) in 14.5% of samples. Commonly mutated oncogenes in melanomas, in particular BRAF(V600E) and NRAS(Q61K/R), were absent. Instead, other genetic alterations known to activate the MAPK and PI3K signaling cascades were identified in 73% of samples, affecting NF1, CBL, ERBB2, MAP2K1, MAP3K1, BRAF, EGFR, PTPN11, MET... (for more see dbGaP study page.)...
  10. Genetic Analysis of Desmoplastic Melanoma dbGaP

    ID: phs000977.v1.p1

    Description: tions included recurrent promoter mutations of NF-kappa B inhibitor epsilon, NFKBIE (IkBε) in 14.5% of samples. Commonly mutated oncogenes in melanomas, in particular BRAF(V600E) and NRAS(Q61K/R), were absent. Instead, other genetic alterations known to activate the MAPK and PI3K signaling cascades were identified in 73% of samples, affecting NF1, CBL, ERBB2, MAP2K1, MAP3K1, BRAF, EGFR, PTPN11, MET, RAC1, SOS2, NRAS, and PIK3CA, some of which being candidates for targeted therapies. Reprinted from: Shain, A. H. et al. Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in...

    Study Types: Tumor vs. Matched-Normal


Displaying 10 of 14 results for "NFKBIE"