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Displaying 32 of 32 results for "NDN"
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  1. Expression data from Mvt-1 clonal isolates over-expressing Ndn 50T or Ndn 50C BioProject

    ID: PRJNA275143

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome ArrayExpress

    ID: E-GEOD-56136

    Description: -of-origin differential gene expression. To study Prader-Willi syndrome (PWS), a developmental imprinting disorder, we generated patient-derived induced pluripotent stem cells (iPSCs) harboring distinct deletions in the ...

  3. The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome BioProject

    ID: PRJNA242529

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Expression data from Mvt-1 clonal isolates over-expressing Ndn 50T or Ndn 50C ArrayExpress

    ID: E-GEOD-65824

    Description: Ndn is a candidate metastasis suppressor gene that has been reported to regulate transcription. We examined the changes in gene exp...

  5. The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome OmicsDI

    ID: E-GEOD-56136

    Date Released: 04-09-2014

    Description: -of-origin differential gene expression. To study Prader-Willi syndrome (PWS), a developmental imprinting disorder, we generated patient-derived induced pluripotent stem cells (iPSCs) harboring distinct deletions in the ...

  6. Recurrent 15q13 microdeletions ArrayExpress

    ID: E-GEOD-10189

    Description: We report a recurrent microdeletion syndrome causing mental retardation, epilepsy and variable facial and digital dysmorphisms. We describe nine patients, including si...

  7. Expression data from Mvt-1 clonal isolates over-expressing Ndn 50T or Ndn 50C OmicsDI

    ID: E-GEOD-65824

    Date Released: 02-22-2016

    Description: Ndn is a candidate metastasis suppressor gene that has been reported to regulate transcription. We examined the changes in gene exp...

  8. Recurrent 15q13 microdeletions BioProject

    ID: PRJNA108297

    Keywords: Variation

    Access Type: download

    dataset.description: We report a recurrent microdeletion syndrome causing mental retardation, epilepsy and variable facial and digital dysmorphisms. We describe nine patients, including si...
  9. Homo sapiens : snoRD116HG transcript regulates the chromatin architecture of MAGEL2 and NDN locus over long distance BioProject

    ID: PRJNA304479

    Keywords: epigenomics

    Access Type: download

  10. PWS Natural History Protocol dbGaP

    ID: phs000575.v1.p1

    Description: ory and the clinical features of individuals with Prader-Willi syndrome and individuals with features of PWS-like/EMO. A blood sample will be obtained from the participants in order to create a DNA and RNA repository. In those PWS participants with a known ...

    Study Types: Case Set

  11. cells from mice reconstituted with wild type and necdin null fetal liver cells following a sublethal dose of irradiation (6,5 Gy)... ArrayExpress

    ID: E-GEOD-39153

    Description: ouse bone marrow reconstituted with wild type and necdin null fetal liver cells The Affymetrix oligonucleotide array was used for this analysis compare the gene expression profile betweenirradiated Lin-Sca-1+c-Kit+ (LSK) cells from mouse bone marrow reconstituted with wi...

  12. Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 GEMMA

    ID: 1613

    Keywords: functional genomics

    Description: alysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. Summary from subseries GSE12227: Gene expression profiling was performed on CNS tissue from neonatal mice carrying the T9H translocation and maternal or paternal duplication of proximal Chromosomes 7 and 15. Our analysis revealed the presence of two novel paternally expressed intergenic transcripts at th...

  13. Gene expression profile of primary cortical neurons from necdin-null mouse embryo ArrayExpress

    ID: E-GEOD-63498

    Description: Necdin, a pleiotropic protein expressed predominantly in postmitotic neurons of mammals, regulates neuronal development and surviva...

  14. cells from mice reconstituted with wild type and necdin null fetal liver cells following a sublethal dose of irradiation (6,5 Gy)... BioProject

    ID: PRJNA170112

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. Transcription profiling of mouse neonatal and embyronic CNS from animals with maternal or paternal duplication of proximal chromosomes 7 and 15 OmicsDI

    ID: E-GEOD-12231

    Date Released: 05-03-2014

    Description: alysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. This SuperSeries is composed of the following subset Series:; GSE12227: Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 (430A); GSE12230: Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 (430B) ...

  16. Transcription profiling of mouse neonates with T9H translocation and maternal or paternal duplication of proximal Chromosomes 7 and 15(430B) ArrayExpress

    ID: E-GEOD-12230

    Description: alysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. Experiment Overall Design: Eight samples were analyzed by microarray analysis using GeneChip 430B (no biological replicates). RNAs were from neonatal cortex and cerebellum, and from whole brain of 13.5 and 15.5 dpc embryos, purified from mice carrying either maternal or paternal duplication of proximal chro...

  17. Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 BioProject

    ID: PRJNA113685

    Access Type: download

    dataset.description: alysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series...
  18. Expression profiling of Ebf2- and Ebf2- stromal cells in mouse bone marrow ArrayExpress

    ID: E-GEOD-51608

    Description: ared to the Ebf2+ cells. These include Nov, Fmod, Ndn, Dcn, Ctgf, Angiopoietin like-1(Angptl1), Fn1 and Jag1, some of which has been reported to be expressed in culture-selected MSCs. Furthermore, consistent with antigen expression analysis by FACS, the Ebf2+ cells highly expressed transcripts of Pdgfra, Pdgfrb, Sca1/Ly6a, Thy1 and Itga7 and Itgav, that have been suggested to be linked to MSCs. Nestin was mainly expressed in the Ebf2+ cells whereas it was hardly detectable in the Ebf2- cells. Altogether, molecularly, the Ebf2...

  19. Necdin, a Negative Growth Regulator, is a Novel STAT3 Target Gene Down-Regulated in Human Cancer ArrayExpress

    ID: E-GEOD-22251

    Description: We took a broad approach to identify novel STAT3 regulated genes by examining changes in the genome-wide gene expression profile by microarray, using ...

  20. Transcription profiling of mouse neonates with T9H translocation and maternal or paternal duplication of proximal Chromosomes 7 and 15(430B) OmicsDI

    ID: E-GEOD-12230

    Date Released: 05-03-2014

    Description: alysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. Experiment Overall Design: Eight samples were analyzed by microarray analysis using GeneChip 430B (no biological replicates). RNAs were from neonatal cortex and cerebellum, and from whole brain of 13.5 and 15.5 dpc embryos, purified from mice carrying either maternal or paternal duplication of proximal chro...

  21. p53 Regulates Hematopoietic Stem Cell Quiescence BioProject

    ID: PRJNA110049

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: wild type and p53 null mice identified Gfi-1 and Necdin as p53 target genes and using lentiviral vectors to upregulate or knockdown the expression of these genes, we show their importance in regulating HSC quiescence. Establishing the role of p53 (and its target genes) in controlling the cell cycle entry of HSCs may lead to therapeutic strategies capable of eliminating quiescent cancer (stem) cells. Overall design: RNAs isolated from wild type, p53 -/- and p53 -/- Mef -/- LSK cells were used in oligonucleotide arrays (Affymetrix)...
  22. Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 (430B) BioProject

    ID: PRJNA113863

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: alysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. Keywords: genetic modification, developmental comparison Overall design: Eight samples were analyzed by microarray analysis using GeneChip 430B (no biological replicates). RNAs were from neonatal cortex and cerebellum, and from whole brain of 13.5 and 15.5 dpc embryos, purified from mice carrying either mat...
  23. Gene expression profile of primary cortical neurons from necdin-null mouse embryo BioProject

    ID: PRJNA268071

    Keywords: Transcriptome or Gene expression

    Access Type: download

  24. to reveal role of insulin receptor substrates and necdin... ArrayExpress

    ID: E-GEOD-2556

    Description: cordant changes in brown adipose tissue in vivo. Necdin was markedly increased in IRS-1 KO cells that could not differentiate, and knockdown of necdin restored brown adipogenesis with down-regulation of Pref-1 and Wnt10a expression. We demonstrated a necdin-E2F4 interaction repressing PPARg transcription. IRS proteins regulated necdin via a CREB dependent pathway, defining a signalling network involved in brown preadipocyte determination....

  25. Transcription profiling of mouse neonatal and embyronic CNS from animals with maternal or paternal duplication of proximal chromosomes 7 and 15 ArrayExpress

    ID: E-GEOD-12231

    Description: alysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. This SuperSeries is composed of the following subset Series:; GSE12227: Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 (430A); GSE12230: Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 (430B) ...

  26. Transcription profiling of mouse HSCs isolated from wild type and p53 null animals reveals p53 Regulates Hematopoietic Stem Cell Quiescence ArrayExpress

    ID: E-GEOD-13448

    Description: wild type and p53 null mice identified Gfi-1 and Necdin as p53 target genes and using lentiviral vectors to upregulate or knockdown the expression of these genes, we show their importance in regulating HSC quiescence. Establishing the role of p53 (and its target genes) in controlling the cell cycle entry of HSCs may lead to therapeutic strategies capable of eliminating quiescent cancer (stem) cells. Experiment Overall Design: RNAs isolated from wild type, p53 -/- and p53 -/- Mef -/- LSK cells were used in oligonucleotide arrays (Affymetrix)...

  27. Expression profiling of Ebf2- and Ebf2- stromal cells in mouse bone marrow OmicsDI

    ID: E-GEOD-51608

    Date Released: 06-03-2014

    Description: ared to the Ebf2+ cells. These include Nov, Fmod, Ndn, Dcn, Ctgf, Angiopoietin like-1(Angptl1), Fn1 and Jag1, some of which has been reported to be expressed in culture-selected MSCs. Furthermore, consistent with antigen expression analysis by FACS, the Ebf2+ cells highly expressed transcripts of Pdgfra, Pdgfrb, Sca1/Ly6a, Thy1 and Itga7 and Itgav, that have been suggested to be linked to MSCs. Nestin was mainly expressed in the Ebf2+ cells whereas it was hardly detectable in the Ebf2- cells. Altogether, molecularly, the Ebf2...

  28. Neonatal and embyronic CNS of mice with maternal or paternal duplication of proximal chromosomes 7 and 15 (430A) BioProject

    ID: PRJNA113857

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: alysis also revealed imprinting of Magel2, Mkrn3, Ndn,Ube3a and Usp29, as well as Pec2 and Pec3 in embryonic brain, 15.5 dpc, and provided a survery of biallelically expressed genes on proximal Chromosomes 7 and 15 in embryonic and neonatal CNS. Keywords: genetic modification, developmental comparison Overall design: Fourteen samples were analyzed by microarray analysis using GeneChip 430A: Six different biological samples were analyzed in duplicate: RNAs were from neonatal cortex and cerebellum, and from whole brain of 15.5 dpc embryos, purified ...
  29. Expression profiling of Ebf2- and Ebf2- stromal cells in mouse bone marrow BioProject

    ID: PRJNA223943

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ared to the Ebf2+ cells. These include Nov, Fmod, Ndn, Dcn, Ctgf, Angiopoietin like-1(Angptl1), Fn1 and Jag1, some of which has been reported to be expressed in culture-selected MSCs. Furthermore, consistent with antigen expression analysis by FACS, the Ebf2+ cells highly expressed transcripts of Pdgfra, Pdgfrb, Sca1/Ly6a, Thy1 and Itga7 and Itgav, that have been suggested to be linked to MSCs. Nestin was mainly expressed in the Ebf2+ cells whereas it was hardly detectable in the Ebf2- cells. Altogether, molecularly, the Ebf2...
  30. Gene-Expression Profiles in IRS Knockout Brown Preadipocytes BioProject

    ID: PRJNA92167

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: cordant changes in brown adipose tissue in vivo. Necdin was markedly increased in IRS-1 KO cells that could not differentiate, and knockdown of necdin restored brown adipogenesis with down-regulation of Pref-1 and Wnt10a expression. We demonstrated a necdin-E2F4 interaction repressing PPARg transcription. IRS proteins regulated necdin via a CREB dependent pathway, defining a signalling network involved in brown preadipocyte determination. Keywords = brown fat Keywords = preadipocyte Keywords = adipogenesis Keywords = mouse Keywords: parallel sample...
  31. Necdin, a Negative Growth Regulator, is a Novel STAT3 Target Gene Down-Regulated in Human Cancer BioProject

    ID: PRJNA128649

    Keywords: Transcriptome or Gene expression

    Access Type: download

  32. 670 Retina

    Biological Entity: Amacrine cell

    Molecular Entity: Ndn


Displaying 32 of 32 results for "NDN"