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Displaying 50 of 804 results for "MYB"
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  1. INK4A expression in leukemic cells transformed by the v-Myb oncoprotein depends on the integrity of the v-Myb leucine zipper region BioProject

    ID: PRJNA152569

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. INK4A expression in leukemic cells transformed by the v-Myb oncoprotein depends on the integrity of the v-Myb leucine zipper region ArrayExpress

    ID: E-GEOD-35413

    Description: The AMV v-Myb oncoprotein causes oncogenic transformation of myelomonocytic cells in vivo and in vitro. Its transforming...

  3. Gene expression analysis of 12 B-cell Chronic Lymphocytic Leukemia samples and 5 CD19+ control samples BioProject

    ID: PRJNA136137

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Gene expression analysis of 12 B-cell Chronic Lymphocytic Leukemia samples and 5 CD19+ control samples OmicsDI

    ID: E-GEOD-26725

    Date Released: 03-01-2011

    Description: (B-CLL). In this study, we present evidence that MYB (v-myb myeloblastosis viral oncogene homolog) is overexpressed in a subset of B-CLL patients. MYB physi...

  5. Gene expression analysis of 12 B-cell Chronic Lymphocytic Leukemia samples and 5 CD19+ control samples ArrayExpress

    ID: E-GEOD-26725

    Description: (B-CLL). In this study, we present evidence that MYB (v-myb myeloblastosis viral oncogene homolog) is overexpressed in a subset of B-CLL patients. MYB physi...

  6. Tumor Suppressor Role for the c-Myb Oncogene in Luminal Breast Cancer BioProject

    ID: PRJNA126079

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. INK4A expression in leukemic cells transformed by the v-Myb oncoprotein depends on the integrity of the v-Myb leucine zipper region OmicsDI

    ID: E-GEOD-35413

    Date Released: 04-23-2012

    Description: The AMV v-Myb oncoprotein causes oncogenic transformation of myelomonocytic cells in vivo and in vitro. Its transforming...

  8. The oncoprotein v-Myb activates transcription of Gremlin 2 during differentiation of the chicken neural crest to melanoblasts OmicsDI

    ID: E-GEOD-39346

    Date Released: 07-23-2012

    Description: ecification and development, we exploited the AMV v-Myb transcriptional regulator, which directs differentiation of in vitro chicken NC cells to the melanocyte lineage. This activity is strictly dependent on v-Myb specifically binding to the Myb recognition DNA element (MRE). The two tamoxifen-inducible v-myb alleles were constructed, one which recognizes the MRE and one which does not. These were activated in ex-ovo NC cells, and the expression profiles of resulting cells were analyzed using Affymetrix microarrays and RT-PCR. These approaches revealed u...

  9. Tumor Suppressor Role for the c-Myb Oncogene in Luminal Breast Cancer ArrayExpress

    ID: E-GEOD-21371

    Description: The transcription factor c-Myb has been well characterized as an oncogene in several human tumor types, and its expres...

  10. The oncoprotein v-Myb activates transcription of Gremlin 2 during differentiation of the chicken neural crest to melanoblasts BioProject

    ID: PRJNA170678

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes OmicsDI

    ID: E-GEOD-34224

    Date Released: 06-02-2014

    Description: The MYB oncogene is widely expressed in acute leukemias and is important for the continued proliferation of leukemia...

  12. Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes BioProject

    ID: PRJNA149777

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. The oncoprotein v-Myb activates transcription of Gremlin 2 during differentiation of the chicken neural crest to melanoblasts ArrayExpress

    ID: E-GEOD-39346

    Description: ecification and development, we exploited the AMV v-Myb transcriptional regulator, which directs differentiation of in vitro chicken NC cells to the melanocyte lineage. This activity is strictly dependent on v-Myb specifically binding to the Myb recognition DNA element (MRE). The two tamoxifen-inducible v-myb alleles were constructed, one which recognizes the MRE and one which does not. These were activated in ex-ovo NC cells, and the expression profiles of resulting cells were analyzed using Affymetrix microarrays and RT-PCR. These approaches revealed u...

  14. Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes ArrayExpress

    ID: E-GEOD-34224

    Description: The MYB oncogene is widely expressed in acute leukemias and is important for the continued proliferation of leukemia...

  15. CRYSTAL STRUCTURE OF C-MYB R2 V103L MUTANT PDB

    ID: PDB:1GVD

    Description: MYB PROTO-ONCOGENE PROTEIN

  16. CRYSTAL STRUCTURE OF C-MYB R2R3 PDB

    ID: PDB:1GV2

    Description: MYB PROTO-ONCOGENE PROTEIN

  17. CRYSTAL STRUCTURE OF C-MYB R1 PDB

    ID: PDB:1GUU

    Description: MYB PROTO-ONCOGENE PROTEIN

  18. CRYSTAL STRUCTURE OF C-MYB R2 PDB

    ID: PDB:1GV5

    Description: MYB PROTO-ONCOGENE PROTEIN

  19. Solution structure of the KIX domain of CBP bound to the transactivation domain of c-Myb PDB

    ID: PDB:1SB0

    Description: protein CBP/protein c-Myb complex

  20. Tumor Suppressor Role for the c-Myb Oncogene in Luminal Breast Cancer OmicsDI

    ID: E-GEOD-21371

    Date Released: 05-01-2014

    Description: The transcription factor c-Myb has been well characterized as an oncogene in several human tumor types, and its expres...

  21. An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma BioProject

    ID: PRJNA307509

    Keywords: Epigenomics

    Access Type: download

  22. Myb specificity determinants BioProject

    ID: PRJNA89889

    Keywords: Transcriptome or Gene expression

    Access Type: download

  23. MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 1 PDB

    ID: PDB:1MBE

    Description: MYB PROTO-ONCOGENE PROTEIN

  24. MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 1 PDB

    ID: PDB:1MBF

    Description: MYB PROTO-ONCOGENE PROTEIN

  25. CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX1 PDB

    ID: PDB:1H88

    Description: CCAAT/ENHANCER BINDING PROTEIN BETA, MYB PROTO-ONCOGENE PROTEIN

  26. Transcription profiling of human MCF7 cells infected with adenovirus expressing c-Myb, v-Myb or the hybrid construct, 3MutC ArrayExpress

    ID: E-GEOD-2815

    Description: The transcriptional activities of c-Myb and its oncogenic variant v-Myb were compared by expressing them in ...

  27. MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3 PDB

    ID: PDB:1MBK

    Description: MYB PROTO-ONCOGENE PROTEIN

  28. MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3 PDB

    ID: PDB:1MBJ

    Description: MYB PROTO-ONCOGENE PROTEIN

  29. MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 2 PDB

    ID: PDB:1MBG

    Description: MYB PROTO-ONCOGENE PROTEIN

  30. Defining the Myb Transcriptional Program Controlled by via Genome-wide Chromatin Occupancy and Expression Analyses ArrayExpress

    ID: E-GEOD-22486

    Description: We used the ERMYB cell line (Hogg et al., Oncogene 15, p2885-2898, 1997) as our model system to identify genes regulated by Myb using w...

  31. CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX2 PDB

    ID: PDB:1H89

    Description: CAAT/ENHANCER BINDING PROTEIN BETA, MYB PROTO-ONCOGENE PROTEIN

  32. MYB silencing in CD34+ progenitor cells BioProject

    ID: PRJNA109945

    Keywords: Transcriptome or Gene expression

    Access Type: download

  33. Transcription profiling of human monocytes infected with adenovirus expressing either c-Myb or v-Myb ArrayExpress

    ID: E-GEOD-2816

    Description: The transcriptional activities of c-Myb and its oncogenic variant v-Myb were compared by expressing them in ...

  34. Defining the Myb Transcriptional Program Controlled by via Genome-wide Chromatin Occupancy and Expression Analyses BioProject

    ID: PRJNA128699

    Keywords: Transcriptome or Gene expression

    Access Type: download

  35. cMyb and vMyb in MCF7 cells BioProject

    ID: PRJNA92417

    Keywords: Transcriptome or Gene expression

    Access Type: download

  36. An Oncogenic Super-Enhancer Formed through Somatic Mutation of a Noncoding Intergenic Element OmicsDI

    ID: E-GEOD-59657

    Date Released: 11-28-2014

    Description: In many cancers, critical oncogenes are driven from large regulatory elements, called super-enhancers, which recruit much of the cell’s transcriptional app...

  37. Expression data from murine acute myeloid leukemia (AML) cells following shRNA-mediated suppression of Myb ArrayExpress

    ID: E-GEOD-30745

    Description: ling following suppression of the driving MLL-AF9 oncogene, and a new Tet-on conditional shRNA expression system we have identified Myb as critical mediator of addiction to MLL-AF9. Suppression of Myb in established AML in vivo terminates aberra...

  38. Expression data from murine acute myeloid leukemia (AML) cells following shRNA-mediated suppression of Myb BioProject

    ID: PRJNA154721

    Keywords: Transcriptome or Gene expression

    Access Type: download

  39. MYB silencing in CD34+ progenitor cells ArrayExpress

    ID: E-GEOD-13110

    Description: The c-Myb transcription factor is highly expressed in immature hematopoietic cells and down-regulated during differe...

  40. An Oncogenic Super-Enhancer Formed through Somatic Mutation of a Noncoding Intergenic Element ArrayExpress

    ID: E-GEOD-59657

    Description: In many cancers, critical oncogenes are driven from large regulatory elements, called super-enhancers, which recruit much of the cell’s transcriptional app...

  41. Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells [EBF1] ArrayExpress

    ID: E-GEOD-35910

    Description: le regulators, is overcome by transformation with v-Abl. The survival defect of transformed Ebf1fl/fl pro-B cells can be rescued by the forced expression of the Ebf1 targets c-Myb or Bcl-xL. In mature B cells, Ebf1 deficiency interferes with the BAFF-R and BCR-dependent Akt signaling pathways, as well as with germinal center formation and class switch recombination. Genome-wide analyses of Ebf1 binding and Ebf1-mediated gene expression in mature B cells and comparison with reported data sets in pro-B cells provide insight into the basis for li...

  42. Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells [H3K4me2 and H3K4me3] ArrayExpress

    ID: E-GEOD-35914

    Description: le regulators, is overcome by transformation with v-Abl. The survival defect of transformed Ebf1fl/fl pro-B cells can be rescued by the forced expression of the Ebf1 targets c-Myb or Bcl-xL. In mature B cells, Ebf1 deficiency interferes with the BAFF-R and BCR-dependent Akt signaling pathways, as well as with germinal center formation and class switch recombination. Genome-wide analyses of Ebf1 binding and Ebf1-mediated gene expression in mature B cells and comparison with reported data sets in pro-B cells provide insight into the basis for li...

  43. An Oncogenic Super-Enhancer Formed through Somatic Mutation of a Noncoding Intergenic Element BioProject

    ID: PRJNA255872

    Keywords: Epigenomics

    Access Type: download

    dataset.description: In many cancers, critical oncogenes are driven from large regulatory elements, called super-enhancers, which recruit much of the cell’s transcriptional app...
  44. cMyb and vMyb in human monocytes BioProject

    ID: PRJNA92419

    Keywords: Transcriptome or Gene expression

    Access Type: download

  45. MYB_BOVIN UniProt:Swiss-Prot

    ID: P46200

    Description: Transcriptional activator Myb HTH myb-type 1 HTH myb-type 2 HTH myb-type 3 H-T-H motif H-T-H motif H...

  46. Structural basis for cooperative transcription factor binding to the CBP coactivator PDB

    ID: PDB:2AGH

    Description: Myb proto-oncogene protein, Crebbp protein, Zinc finger protein HRX

  47. NMR solution structure of a MYB-like DNA binding domain of KNL-2 from C. Elegans PDB

    ID: PDB:2M3A

    Description: Protein KNL-2

  48. Defining the Myb Transcriptional Program Controlled by via Genome-wide Chromatin Occupancy and Expression Analyses OmicsDI

    ID: E-GEOD-22486

    Date Released: 03-27-2012

    Description: We used the ERMYB cell line (Hogg et al., Oncogene 15, p2885-2898, 1997) as our model system to identify genes regulated by Myb using w...

  49. Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-Cell Acute Lymphoblastic Leukemia BioProject

    ID: PRJNA363039

    Keywords: Epigenomics

    Access Type: download

  50. Effect of c-Myb deficiency on pre-selection DP thymocytes BioProject

    ID: PRJNA122245

    Keywords: Transcriptome or Gene expression

    Access Type: download


Displaying 50 of 804 results for "MYB"