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Displaying 10 of 35 results for "MIR146B"
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  1. microRNA-146b improves intestinal injury in mouse colitis by activating NF-kB and improving epithelial barrier function OmicsDI

    ID: E-GEOD-40708

    Date Released: 09-26-2012

    Description: ear. The present study investigated the effect of microRNA (miR-146b) on improving intestinal inflammation. Methods: The microRNA profile in IL-10-deficient mice was examined using

  2. Modulation of mucosal immune responses to Clostridium difficile by peroxisome proliferator-activated receptor γ and microRNA-146b BioProject

    ID: PRJNA170259

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. microRNA-146b improves intestinal injury in mouse colitis by activating NF-kB and improving epithelial barrier function BioProject

    ID: PRJNA174740

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. MicroRNA profiling of bleomycin-induced pulmonary fibrosis in mice ArrayExpress

    ID: E-GEOD-45789

    Description: y and hyperplasia. To determine if alterations in microRNA expression contribute to these phenotypes, microRNA expression profiling of the lungs from bleomycin treated C57Bl/6J mice, relative to that of untreated controls, was undertaken. Mice were treated at 8 weeks old with 100 Units/kg of bleomycin delivered subcutaneou...

  5. microRNA-146b improves intestinal injury in mouse colitis by activating NF-kB and improving epithelial barrier function ArrayExpress

    ID: E-GEOD-40708

    Description: ear. The present study investigated the effect of microRNA (miR-146b) on improving intestinal inflammation. Methods: The microRNA profile in IL-10-deficient mice was examined using

  6. MicroRNA-146 function in the innate immune response of zebrafish embryos to Salmonella typhimurium infection [RNA-seq] OmicsDI

    ID: E-GEOD-45209

    Date Released: 10-03-2013

    Description: an in vivo system to investigate the role of the microRNA-146 family (consisting of 2 members miR-146a and miR-146b) in the innate immune response to S...

  7. MicroRNA-146 function in the innate immune response of zebrafish embryos to Salmonella typhimurium infection [RNA-seq] ArrayExpress

    ID: E-GEOD-45209

    Description: an in vivo system to investigate the role of the microRNA-146 family (consisting of 2 members miR-146a and miR-146b) in the innate immune response to S...

  8. MicroRNA-146 function in the innate immune response of zebrafish embryos to Salmonella typhimurium infection [RNA-seq] BioProject

    ID: PRJNA193208

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells During Carcinogenesis. OmicsDI

    ID: E-GEOD-63511

    Date Released: 08-29-2015

    Description: PTC. The integrated analyses identified a master microRNA regulatory network in PTC that is involved in essential biological processes such as thyroid differentiation. As both mature products of miR-146b (miR-146b-5p and -3p) were among the most abundant upregulated in tumors, we unveil their target genes and found that miR-146b-3p specifically binds to the 3`UTR of PAX8 and NIS, leading to an impaired translation of the proteins and subsequently decreasing the iodide uptake of the cells. Furthermore, we show that mir-146b and PAX8 regulate each other, describing a novel regulatory circuit that determines the differentiated phenotype of PTC. In conclusion, our integrative genomic analysis uncovers the target genes of two of the most upregulated miRNAs and highlights the importanc...

  10. The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells During Carcinogenesis ArrayExpress

    ID: E-GEOD-63511

    Description: PTC. The integrated analyses identified a master microRNA regulatory network in PTC that is involved in essential biological processes such as thyroid differentiation. As both mature products of miR-146b (miR-146b-5p and -3p) were among the most abundant upregulated in tumors, we unveil their target genes and found that miR-146b-3p specifically binds to the 3`UTR of PAX8 and NIS, leading to an impaired translation of the proteins and subsequently decreasing the iodide uptake of the cells. Furthermore, we show that mir-146b and PAX8 regulate each other, describing a novel regulatory circuit that determines the differentiated phenotype of PTC. In conclusion, our integrative genomic analysis uncovers the target genes of two of the most upregulated miRNAs and highlights the importanc...


Displaying 10 of 35 results for "MIR146B"