MCOLN1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 16 of 16 results for "MCOLN1"
i
  1. I-II linker of TRPML1 channel at pH 6 PDB

    ID: PDB:5TJA

    Description: Mucolipin-1

  2. I-II linker of TRPML1 channel at pH 7.5 PDB

    ID: PDB:5TJC

    Description: Mucolipin-1

  3. I-II linker of TRPML1 channel at pH 4.5 PDB

    ID: PDB:5TJB

    Description: Mucolipin-1

  4. The Natural History of Mucolipidosis Type IV - LDN 6704 BioProject

    ID: PRJNA378816

    Keywords: Phenotype or Genotype

    Access Type: download

    dataset.description: Mucolipidosis type IV (MLIV) is an autosomal recessive disorder typically characterized by severe psychomotor delay evident by the end of the first year o...
  5. The Natural History of Mucolipidosis Type IV - LDN 6704 BioProject

    ID: PRJNA378815

    Access Type: download

    dataset.description: Mucolipidosis type IV (MLIV) is an autosomal recessive disorder typically characterized by severe psychomotor delay evident by the end of the first year o...
  6. MCLN1_MOUSE UniProt:Swiss-Prot

    ID: Q99J21

    Description: Mucolipin-1 Helical Helical Helical Helical Helical Helical Phosphoserine Phosphoserine In isoform 2.

  7. Gene expression profile in individuals affected by Mucolipidosis type IV ArrayExpress

    ID: E-GEOD-5444

    Description: om individuals affected by Mucolipidosis type IV (MLIV) and healthy ones (AB). We directly compared MLIV indivisuals versus normal controls. A total of four technical replicate hybridizations were performed....

  8. Gene expression profile in individuals affected by Mucolipidosis type IV BioProject

    ID: PRJNA96115

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: om individuals affected by Mucolipidosis type IV (MLIV) and healthy ones (AB). Keywords: Disease state analysis Overall design: We directly compared MLIV indivisuals versus normal controls. A total of four technical r...
  9. Data from: Gene-wise association of variants in four lysosomal storage disorder genes in neuropathologically confirmed Lewy Body disease Dryad

    DateIssued: 05-14-2015

    Description: of four LSD genes including GBA, HEXA, SMPD1, and MCOLN1 in 231 brain autopsies. Brain autopsies included neuropathologically defined LBD without Alzheimer Disease (AD) changes (n = 59), AD without significant LB pathology (n = 71), Alzheimer disease and lewy body variant (ADLBV) (n = 68), and control brains without LB or AD neuropathology (n = 33). Sequencing of HEXA, SMPD1, MCOLN1 and GBA foll...

  10. Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection ArrayExpress

    ID: E-GEOD-79508

    Description: evented cleavage of the lysosomal calcium channel TRPML1. These events drove transcription of lysosomal and autophagy genes via the transcription factor TFEB, which increased lysosomal biogenesis and activation of autophagy-initiation kinase ULK1 for clearance of the bacteria. Our results identified a fundamental biological function of cathepsin B in providing a checkpoint for homeostatic maintenance of lysosome population and basic recycling functions in the cell. We used microarrays to explore the gene expression profiles differentially expressed in bone marrow-derived macrophages (BMDM) isolated from cathepsin B-/- and wild-type mice....

  11. Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection BioProject

    ID: PRJNA316012

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: evented cleavage of the lysosomal calcium channel TRPML1. These events drove transcription of lysosomal and autophagy genes via the transcription factor TFEB, which increased lysosomal biogenesis and activation of autophagy-initiation kinase ULK1 for clearance of the bacteria. Our results identified a fundamental biological function of cathepsin B in providing a checkpoint for homeostatic maintenance of lysosome population and basic recycling functions in the cell. Overall design: We used microarrays to explore the gene expression profiles differentially expressed in bone marrow-derived macrophages (BMDM) isolated from cathepsin B-/- and wild-type mice....
  12. MCLN1_MACFA UniProt:Swiss-Prot

    ID: Q60HE8

    Description: Mucolipin-1 Helical Helical Helical Helical Helical Helical Phosphoserine Phosphoserine

  13. Gene expression profile in individuals affected by Mucolipidosis type IV OmicsDI

    ID: E-GEOD-5444

    Date Released: 03-27-2012

    Description: om individuals affected by Mucolipidosis type IV (MLIV) and healthy ones (AB). We directly compared MLIV indivisuals versus normal controls. A total of four technical replicate hybridizations were performed....

  14. Census of retail trade, 1972 summary statistics file ML Dataverse

    Description: ted detail within these major lines classified by 1 13 kinds-of-business. ML4 has information on sales of establishments reporting merchandise lines as a percent of total sales in the kind-of-business specified. This data can be used as a guideline to evaluate the merchandise line tabulations. Each of the files has slightly different geography for which summaries are presented. ML1 has summaries for the total United States and States, ML2 has information for each State outside SMSAs, ML3 provides summaries for each SMSA, and ML4 presents data for the United States, States, SMSAs, an...

    Person: U.S. Bureau of the Census United States

    Release Date: 11-30-2007

  15. Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection OmicsDI

    ID: E-GEOD-79508

    Date Released: 08-14-2016

    Description: evented cleavage of the lysosomal calcium channel TRPML1. These events drove transcription of lysosomal and autophagy genes via the transcription factor TFEB, which increased lysosomal biogenesis and activation of autophagy-initiation kinase ULK1 for clearance of the bacteria. Our results identified a fundamental biological function of cathepsin B in providing a checkpoint for homeostatic maintenance of lysosome population and basic recycling functions in the cell. We used microarrays to explore the gene expression profiles differentially expressed in bone marrow-derived macrophages (BMDM) isolated from cathepsin B-/- and wild-type mice....

  16. Census of Retail Trade Summary Files Dataverse

    Description: Series (RA). There are four ML files (ML1 through ML4). ML1, ML2, and ML3 enumerate the number of establishments, sales, sales of specified merchandise line as a percent of total sales of establishments handling the line, and sales of specified merchandise lines as a percent of total sales of all establishments in this kind of business category. The data are given for 27 broad merchandise lines, and for selected detail within these major lines classified by 113 kinds of business. ML1 has data for the U.S. and for states. ML2 has data for each state outside Standard Metropolitan Statistical Areas (SMSAs). ML3 has data for each SMSA. ML4 has information on sales of establishments reporting mercha...

    Person: Department of Commerce. Bureau of the Census. Office of the Associate Director for Economic Programs. Business Division. (01/1987 - 1994)

    Release Date: 08-24-2007


Displaying 16 of 16 results for "MCOLN1"