MAP2K1 | bioCADDIE Data Discovery Index
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Displaying 20 of 834 results for "MAP2K1"
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  1. MEK1 IN COMPLEX WITH BI 847325 PDB

    ID: PDB:5EYM

    Description: Dual specificity mitogen-activated protein kinase kinase 1

  2. CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN MAP KINASE KINASE 1 (MEK1) IN COMPLEX WITH A SMALL MOLECULE INHIBITOR AND ADP PDB

    ID: PDB:4ARK

    Description: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1

  3. Mitogen-activated protein kinase kinase 1 (MEK1) in complex with CH4858061 and MgATP PDB

    ID: PDB:3OS3

    Description: Dual specificity mitogen-activated protein kinase kinase 1

  4. Crystal structure of MEK1 in complex with fragment 3 PDB

    ID: PDB:3ZLW

    Description: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1

  5. Crystal Structure of MEK1 kinase bound to GDC0973 PDB

    ID: PDB:4LMN

    Description: Dual specificity mitogen-activated protein kinase kinase 1

  6. Expression Data from 24 orthotopic tumors grown in the pancreas of mice +/- MEK inhibitor PD0325901 ArrayExpress

    ID: E-GEOD-45758

    Description: Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity. We used m...

  7. Crystal structure of the BRAF:MEK1 complex PDB

    ID: PDB:4MNE

    Description: Dual specificity mitogen-activated protein kinase kinase 1

  8. KSR2-MEK1 HETERODIMER PDB

    ID: PDB:2Y4I

    Description: KINASE SUPPRESSOR OF RAS 2, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN

  9. BTH treated mkk1, mkk2 and mkk1/2 knockout mutant BioProject

    ID: PRJNA107725

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. KSR2:MEK1 Complex Bound to the Small Molecule APS-2-79 PDB

    ID: PDB:5KKR

    Description: Kinase suppressor of Ras 2 (E.C.2.7.11.1), Dual specificity mitogen-activated

  11. Crystal structure of MEK1 in complex with fragment 6 PDB

    ID: PDB:3ZLS

    Description: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1

  12. Crystal structure of MEK1 in complex with fragment 18 PDB

    ID: PDB:3ZLX

    Description: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1

  13. Expression Data from 22 human pancreatic cancer cell lines grown in triplicates +/- MEK inhibitor CI-1040 ArrayExpress

    ID: E-GEOD-45757

    Description: Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity. We used m...

  14. Crystal structure of MEK1 in complex with fragment 8 PDB

    ID: PDB:3ZLY

    Description: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1

  15. Analysis of A375 and A375 clones that acquired resistance to GSK2118436 after treatment with GSK2118436 (GSK436), GSK1120212 (GSK212), or the combinat... BioProject

    ID: PRJNA152855

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: resistance clones acquired mutations in NRAS and MEK1. One clones, 16R6-4, acquired two mutations in NRAS – Q61K and A146T. Proliferation and western blot analyses demonstrated that these clones were insensitive to single agent GSK2118436 or GSK1120212 (an allosteric MEK inhibitor) but were sensitive to the combination of GSK2118436 and GSK1120212. To further characterize this combi...
  16. Crystal structure of MEK1 in complex with fragment 1 PDB

    ID: PDB:3ZM4

    Description: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1

  17. Transcription profiling by array of human MCF10A cells over-expressing HRas or MEK1 ArrayExpress

    ID: E-GEOD-12764

    Description: MCF10A cells were then transfected with MEK1(S217S221), HRAS(G12V), and null control vectors; Cells were lysed 24 hours post-transfection with collection of total RNA and ...

  18. Analysis of A375 and A375 clones that acquired resistance to GSK2118436 after treatment with GSK2118436 (GSK436), GSK1120212 (GSK212), or the combinat... ArrayExpress

    ID: E-GEOD-35230

    Description: resistance clones acquired mutations in NRAS and MEK1. One clones, 16R6-4, acquired two mutations in NRAS – Q61K and A146T. Proliferation and western blot analyses demonstrated that these clones were insensitive to single agent GSK2118436 or GSK1120212 (an allosteric MEK inhibitor) but were sensitive to the combination of GSK2118436 and GSK1120212. To further characterize this combi...

  19. Transcriptome of mkk1-mkk2 mutants ArrayExpress

    ID: E-GEOD-24516

    Description: au08-02_mkk1-mkk2 - mkk1-mkk2 - Functional redundancy of the two MAPKKs MKK1 and MKK2. - mkk1 and mkk2 k.o. plant...

  20. Microarray analysis of gene expression profiles in Map2k1+/-Map2k2+/- and Map2k1flox/-Map2k2+/-Tg+/Sox2Cre placentas ArrayExpress

    ID: E-GEOD-51644

    Description: The mammalian genome contains two ERK/MAP kinase kinase genes, Map2k1 and Map2k2, encoding dual-specificity kina...


Displaying 20 of 834 results for "MAP2K1"