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Displaying 20 of 273 results for "JAK3"
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  1. Crystal structure of Jak3 complexed to N-[3-(6-Phenylamino-pyrazin-2-yl)-3H-benzoimidazol-5-yl]-acrylamide PDB

    ID: PDB:4QPS

    Description: Tyrosine-protein kinase JAK3 (E.C.2.7.10.2)

  2. Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family PDB

    ID: PDB:3PJC

    Description: Tyrosine-protein kinase JAK3 (E.C.2.7.10.2)

  3. Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6 PDB

    ID: PDB:3LXN

    Description: Non-receptor tyrosine-protein kinase TYK2 (E.C.2.7.10.2)

  4. JAK3 kinase domain in complex with 1-[(3S)-1-isobutylsulfonyl-3-piperidyl]-3-(5H-pyrrolo[2,3-b]pyrazin-2-yl)urea PDB

    ID: PDB:4QT1

    Description: Tyrosine-protein kinase JAK3 (E.C.2.7.10.2)

  5. JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-2-hydroxy-1,2-dimethyl-propyl)-amide PDB

    ID: PDB:4HVG

    Description: Tyrosine-protein kinase JAK3 (E.C.2.7.10.2)

  6. JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((R)-2-hydroxy-1,2-dimethyl-propyl PDB

    ID: PDB:4HVH

    Description: Tyrosine-protein kinase JAK3 (E.C.2.7.10.2)

  7. Crystal Structure of JAK3 Kinase Domain in Complex with a Pyrrolopyrazine-2-phenyl Ether Inhibitor PDB

    ID: PDB:3ZEP

    Description: TYROSINE-PROTEIN KINASE JAK3 (E.C.2.7.10.2, 2.7.1.112)

  8. Genetic characterization of T-PLL reveals two major biologic subgroups and JAK3 mutations as prognostic marker BioProject

    ID: PRJNA274578

    Keywords: Variation

    Access Type: download

  9. Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6 PDB

    ID: PDB:3LXP

    Description: Non-receptor tyrosine-protein kinase TYK2 (E.C.2.7.10.2)

  10. Expression data from NKYS transfected with siRNAs or plasmids BioProject

    ID: PRJNA305040

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: The siRNA transfection includes JAK3 and EZH2 siRNAs. The plasmid transfection includes EZH2 WT and its mutants. We used gene expression data from JAK3
  11. Expression data from NKYS transfected with siRNAs or plasmids ArrayExpress

    ID: E-GEOD-75680

    Description: The siRNA transfection includes JAK3 and EZH2 siRNAs. The plasmid transfection includes EZH2 WT and its mutants. We used gene expression data from JAK3

  12. JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide PDB

    ID: PDB:4HVD

    Description: Tyrosine-protein kinase JAK3 (E.C.2.7.10.2)

  13. Homo sapiens : Modeling Human Severe Combined Immunodeficiency and Correction by CRISPR/Cas9 Enhanced Gene Replaceme BioProject

    ID: PRJNA278160

    Keywords: genome sequencing

    Access Type: download

    dataset.description: Mutations of the Janus family kinase JAK3 gene cause severe combined immunodeficiency (SCID). JAK3 deficiency in humans is characterized by the absen...
  14. Crystal Structure of the Jak3 Kinase Domain Covalently Bound to N-(3-(((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)m... PDB

    ID: PDB:4Z16

    Description: Tyrosine-protein kinase JAK3 (E.C.2.7.10.2)

  15. JAK3 in complex with a covalent EGFR inhibitor PDB

    ID: PDB:4V0G

    Description: TYROSINE-PROTEIN KINASE JAK3 (E.C.2.7.10.2)

  16. Gene expression of Kit225 cells upon NC1153 treatment BioProject

    ID: PRJNA117747

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: NC1153 was shown to inhibit JAK3 tyrosine kinase. Lymphocytes survival depends on the integrity of STAT5, the primary downstream target of JAK3
  17. Effect of JAK1/3 blockade on IL2 response in NK cells BioProject

    ID: PRJNA329657

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: IL2 signals are transmitted through JAK1 and JAK3, but the transcriptomic consequences of each to the overall response is unclear. Here we analyzed the relative contribution of...
  18. Expression data from NKYS transfected with siRNAs or plasmids OmicsDI

    ID: E-GEOD-75680

    Date Released: 07-30-2016

    Description: The siRNA transfection includes JAK3 and EZH2 siRNAs. The plasmid transfection includes EZH2 WT and its mutants. We used gene expression data from JAK3

  19. Effect of JAK1/3 blockade on IL2 response in NK cells ArrayExpress

    ID: E-GEOD-84562

    Description: IL2 signals are transmitted through JAK1 and JAK3, but the transcriptomic consequences of each to the overall response is unclear. Here we analyzed the relative contribution of...

  20. Gene expression of Kit225 cells upon NC1153 treatment ArrayExpress

    ID: E-GEOD-17007

    Description: NC1153 was shown to inhibit JAK3 tyrosine kinase. Lymphocytes survival depends on the integrity of STAT5, the primary downstream target of JAK3


Displaying 20 of 273 results for "JAK3"