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Displaying 10 of 195 results for "INPP5D"
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  1. Role and function of Inpp5d in BCR-ABL1 driven pre-B cells BioProject

    ID: PRJNA150229

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. DOK3_CHICK UniProt:Swiss-Prot

    ID: A3R064

    Description: y-Glu Phosphotyrosine Abolishes interaction with INPP5D/SHIP Strongly reduced tyrosine phosphorylation. Abolishes interaction with GRB2 and INPP5D/SHIP...

  3. DOK3_MOUSE UniProt:Swiss-Prot

    ID: Q9QZK7

    Description: uced IL2 secretion. No effect on interaction with INPP5D SH2 domain. Abolishes interaction with CSK SH2 domain. No effect on BCR-triggered tyrosine phosphorylation. Abolishes reduction of BCR-induced IL2 secretion, the interaction with INPP5D SH2 domain and BCR-triggered tyrosine phosphorylation; when associated with F-343 Some reduction of BCR-induced IL2 secretion. Some interaction with INPP5D SH2 domain. Some decrease in BCR-trig...

  4. Role and function of Inpp5d in BCR-ABL1 driven pre-B cells ArrayExpress

    ID: E-GEOD-34830

    Description: In order to investigate the function of Inpp5d in ALL, we isolated bone marrow cells from Inpp5d fl/fl mice and transformed them with BCR-ABL1. In a sec...

  5. Role and function of Inpp5d in BCR-ABL1 driven pre-B cells OmicsDI

    ID: E-GEOD-34830

    Date Released: 06-17-2013

    Description: In order to investigate the function of Inpp5d in ALL, we isolated bone marrow cells from Inpp5d fl/fl mice and transformed them with BCR-ABL1. In a sec...

  6. Solution structure of the human SHIP SH2 domain PDB

    ID: PDB:2YSX

    Description: Signaling inositol polyphosphate phosphatase SHIP II

  7. miRNA expression patterns in immature and CpG stimulated murine BMDCs ArrayExpress

    ID: E-GEOD-72716

    Description: s showed that miR-155 influenced the level of the phosphatase SHIP1 in DCs, and that the lack of SHIP1 in DCs was sufficient to break T cell tolerance in vivo, again in the absence of TLR induced DC maturation. Our study demonstrates that the overexpression of miR-155 in DCs is a critical event that is alone sufficient to break self tolerance and promote a CD8-mediated autoimmune response in vivo. This process is independent of the induction of conventional DC maturation markers, indicating that miR-155 regulation of SHIP represents a unique axis that regulates DC function in vivo. Dendritic cell culture: Bone marrow was flushed from tibias and femurs of mice with HBSS. Bone marrow cells were cultured at 2x106 cells/ml in 10 ml non-tissue culture treated dishes in RPMI 1640 containing 10% LPS-free FBS, Penicillin:streptomycin glutamine 2-mercaptoethanol (cRPMI), with 40ng/ml murine GM-CSF (Peprotech). On day 3 of cultures 10ml of fresh media was added also containing 40ng/ml GM-CSF. On days 6 and 8, 10ml of media was removed and centrifuged to collect cells, which were resuspended in 10ml f...

  8. Concerted action of Helios and Ikaros balances the strength of B cell receptor signaling and controls the expression of inositol 5-phosphatase SHIP BioProject

    ID: PRJNA124429

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. Concerted action of Helios and Ikaros balances the strength of B cell receptor signaling and controls the expression of inositol 5-phosphatase SHIP ArrayExpress

    ID: E-GEOD-20946

    Description: Inositol 5-phosphatase SHIP is differentially expressed in Ikaros and Heli...

  10. Data from: Is sex advantageous in adverse environments? A test of the abandon-ship hypothesis Dryad

    DateIssued: 05-31-2017

    Description: oth sexual and asexual reproduction). The abandon-ship hypothesis predicts higher allocation to sex under stress to allow low-fitness individuals to recombine their genotype, potentially increasing offspring fitness. However, effective tests of the abandon-ship hypothesis, particularly in multicellular organisms, are lacking. Here we test the abandon-ship hypothesis,...


Displaying 10 of 195 results for "INPP5D"