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Displaying 20 of 53 results for "HNRNPA2B1"
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  1. Analysis of pre-mRNA splicing trans-regulation in human lymphoblastoid cell lines BioProject

    ID: PRJNA230267

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Sumoylated hnrnpa2b1 controls the sorting of miRNAs into two exosomes through binding to specific motifs ProteomeXchange

    ID: PXD000350

    Instrument: LTQ Orbitrap

    Date Released: 04-16-2014

  3. Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins (RNA-Seq) BioProject

    ID: PRJNA156297

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: we present a comprehensive study to elucidate how heterogeneous nuclear ribonucleoparticle (hnRNP) proteins, among the most abundant RNA binding proteins, coordinate to regulate alternative pre-mRNA splicing (AS) in human cells. Using splicing-sensitive microarrays, cross-link...
  4. Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins (CLIP-Seq) BioProject

    ID: PRJNA156301

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: we present a comprehensive study to elucidate how heterogeneous nuclear ribonucleoparticle (hnRNP) proteins, among the most abundant RNA binding proteins, coordinate to regulate alternative pre-mRNA splicing (AS) in human cells. Using splicing-sensitive microarrays, cross-link...
  5. Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins (splicing arrays) BioProject

    ID: PRJNA156299

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: we present a comprehensive study to elucidate how heterogeneous nuclear ribonucleoparticle (hnRNP) proteins, among the most abundant RNA binding proteins, coordinate to regulate alternative pre-mRNA splicing (AS) in human cells. Using splicing-sensitive microarrays, cross-link...
  6. MK886 treatment of H720 non-small cell lung cancer cell line BioProject

    ID: PRJNA92869

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Systematic Discovery of Structural Elements Governing Mammalian mRNA Stability ArrayExpress

    ID: E-GEOD-35800

    Description: Decoding post-transcriptional regulatory programs underlying gene expression is a crucial step toward a predictive dynamical understanding of cellular...

  8. MK886 treatment of H720 non-small cell lung cancer cell line GEMMA

    ID: 2231

    Keywords: functional genomics

    Description: In this experiments different treatments were applied to lung cancer cell lines 1)H720 cell line suspension was treated by 1 micromole of 5-lipoxygen...

  9. Arabidopsis Messenger RNA N6-methyladenosine Demethylation Regulates Plant Development OmicsDI

    ID: E-GEOD-79523

    Date Released: 03-25-2016

    Description: proteins, such as YTH domain family proteins and HNRNPA2B1; m6A can also act as a structure switch to affect RNA-protein interactions for biological regulation. In Arabidopsis thaliana, the methyltransferase subunit MTA (the plant orthologue of human METTL3, encoded by At4g10760) was well characterized and FIP37 (the plant orthologue of human WTAP) was first identified as the interacting partner of MTA. Here we report the discovery and characterization of reversible m6A methylation mediated by AtALKBH10B (encoded by At4g02940) in A. thaliana, and noticeable roles of this RNA demethylase in affecting plant development and floral transition. Our findings reveal potential broad functions o...

  10. Arabidopsis Messenger RNA N6-methyladenosine Demethylation Regulates Plant Development ArrayExpress

    ID: E-GEOD-79523

    Description: proteins, such as YTH domain family proteins and HNRNPA2B1; m6A can also act as a structure switch to affect RNA-protein interactions for biological regulation. In Arabidopsis thaliana, the methyltransferase subunit MTA (the plant orthologue of human METTL3, encoded by At4g10760) was well characterized and FIP37 (the plant orthologue of human WTAP) was first identified as the interacting partner of MTA. Here we report the discovery and characterization of reversible m6A methylation mediated by AtALKBH10B (encoded by At4g02940) in A. thaliana, and noticeable roles of this RNA demethylase in affecting plant development and floral transition. Our findings reveal potential broad functions o...

  11. PRJNA152199 BioProject

    Access Type: download

  12. Analysis of the gene expression pattern of bovine blastocysts at three stages of development OmicsDI

    ID: E-GEOD-25606

    Date Released: 05-03-2014

    Description: ion. Gene candidates (IFNt, PLAC8, SSLP1, AKR1B1, HNRNPA2B1, ARGFX, NANOS, CCNB1) were selected and confirmed using Q-RT-PCR to validate the microarray data. Results: Our analysis show that hatched blastocysts are enriched in genes transcripts implicated in implantation, cell adhesion and extracellular matrix digestion. Early blastocysts expressed genes mainly involved in cell cycle control, transcription and translation. Q-RT-PCR validated most microarray results (87.5%). Some of the differentially expressed genes are interesting as potential markers of competence. Conclusions: Overall, our study provides new insights into the molecular regulation of blastocyst formation. In addition, it could help assess blastocyst staging and select better embryos based on the expression of quality markers. In the present study the Laval/Sirard_bovine_embryo_3K_V3.0 array was used to conduct a series of 18 hybridizations (for three Blastocysts stages (early, expended, hatched) with three biological replicates and dye swaps) in a loop design experiment....

  13. Dysregulated Expression of Lipid Storage and Membrane Dynamics Factors in Tia1 Knock-Out Mouse Nervous Tissue OmicsDI

    ID: E-GEOD-54418

    Date Released: 10-11-2014

    Description: components such as TDP-43, FUS, ATXN2, SMN, MAPT, HNRNPA2B1 and HNRNPA1 are crucial for the motor neuron diseases ALS / SMA and for the frontotemporal dementia FTD, here we studied mouse nervous tissue to identify mRNAs with selective dependence on Tia1 deletion. Transcriptome profiling with oligonucleotide microarrays in comparison of spinal cord and cerebellum, together with independent validation in quantitative reverse transcriptase PCR and immunoblots demonstrated several strong and consistent dysregulations. In...


Displaying 20 of 53 results for "HNRNPA2B1"