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Displaying 20 of 316 results for "GLI2"
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  1. Effect of simultaneous activation of TGFbeta and TLR4 pathway in human monocytes ArrayExpress

    ID: E-GEOD-17909

    Description: eous stimulation of TLR4 and TGFβ signaling. THP-1 cells, a human monocytic cell line, were stimulated for 24 hours with PBS as control, LPS (100ng/ml), TGFbeta1 (1ng/ml) or LPS (100ng/ml) + TGFbeta1 (1ng/ml). After 24 hours of stimulation, total RNA was isolated and prepared for genome wide analyses using Illumina HumanRef8 V3.0 Beadchips. In total 32 arrays were analyzed including 8 samples of PBS-stimulat...

  2. Transcription profiling of human leukemia cell lines KG-1, U937 and THP-1 vs. normal human blood monocytes ArrayExpress

    ID: E-GEOD-3280

    Description: sion profiles of the three leukemia cell lines KG-1, U937 and THP-1 was compared to normal human blood monocytes (reference). The set includes a single hybridization for each sample....

  3. Mesenchymal stromal cells from neonatal tracheal aspirates demonstrate a pattern of gene expression consistent with a lung origin OmicsDI

    ID: E-GEOD-24583

    Date Released: 06-10-2011

    Description: ranscription factors Tbx2, Tbx3, Wnt5a, FoxF1 and Gli2, each of which have been associated with lung development. Compared to lung fibroblasts, 710 gene probe transcripts were differentially expressed by the lung MSCs, including IL-6 and IL-8/CXCL8. Further, neonatal lung MSCs exhibited a pattern of Hox gene expression distinct from cord-blood MSCs but similar to human fetal lung fibroblasts, consistent with a lung origin. Together, these data suggest that MSCs isolated from neonatal tracheal aspirates originate in the lung and are distinct from lung fibroblasts....

  4. The sigma factor E of Mycobacterium tuberculosis modulates the inflammatory response of human THP1 cells OmicsDI

    ID: E-GEOD-7870

    Date Released: 05-02-2014

    Description: sponse. We compared the global gene expression of THP1 macrophages infected with H37Rv and SigE to the gene expression profile of uninfected macrophages....

  5. Genome-wide analysis of vitamin D receptor (VDR) target genes in THP-1 monocytic leucemia cells BioProject

    ID: PRJNA141809

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. THP-1 human monocytes Transcriptome following exposure to S-nitrosoglutathione (GSNO) BioProject

    ID: PRJNA284337

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Gene expression analysis of KLF4 expression in THP-1 cells with CRISPR knockout of miR-150 and p21 (CDKN1A) BioProject

    ID: PRJNA297123

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. NanoString miRNA profiling of THP1-differentiated macrophages treated with LPS derived from A. aggregatibacter, P. gingivalis and Pg LPS treated with cigrate smo... ArrayExpress

    ID: E-GEOD-43411

    Description: sion of ~200 (30%) miRNAs across all samples. THP-1 differentiated cells were treated in duplicates with Aa, Pg and Pg (CSE) LPS for 4h and the cells were harvested after washing twice with PBS. Total RNA was isolated using miRNeasy kit (Qiagen). Samples were then processed for Nanostring profiling....

  9. Gene expression analysis of TRIM5 KD in the THP1 cell line OmicsDI

    ID: E-GEOD-25041

    Date Released: 06-10-2011

    Description: IM5 we used the myelomonocytic leukemia cell line THP1. These cells were transduced with a lentiviral vector that delivers a miRNA engineered to knockdown TRIM5. The vector also encoded a puromycin-resistance cassette and transduced cells were selected in poold with puromycin. As a control, cells were transd...

  10. in vivo and in vitro study of asthma OmicsDI

    ID: E-GEOD-27876

    Date Released: 06-02-2014

    Description: ene expression patterns of the LPS or HDM-treated THP1 cells compared with those from non-treated THP1 cells. And we analyzed the microarray data through clustering analysis, signaling pathway analysis and others. Ten milliliters of peripheral blood of five mild asthma, five severe asthma and five normal subjects were centrifuged at 4000 rpm for 20 min to collect 0.4 mL of the buffy coat fraction for in vivo study. To induce an inflammatory response, for in vitro study, the THP1 cells were seeded in 12-well plates at a density of 1 × 106...

  11. Effects of PMA on exon usage of HL60, THP-1, and U937 cells BioProject

    ID: PRJNA125221

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Flagellin_Illumina_Microarray ArrayExpress

    ID: E-MTAB-2395

    Description: phi and host cells. A macrophage-like cell line (THP1) and an epithelial cell line (Hep2) were infected with S. Typhi expressing one of three flagellin variants: Hd, Hj or Hz66. A non-flagellated mutant (DfliC) and a non-invasive mutant (DinvA) were used as controls...

  13. TREX2 M-region PDB

    ID: PDB:5UBP

    Description: se transcriptional regulator, Nuclear mRNA export protein THP1, 26S proteasome complex subunit SEM1...

  14. Profiling the gene expression for aLTA and pLTA effect in THP1 BioProject

    ID: PRJNA115675

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. Expression data from Saccharomyces cerevisiae strains deleted for the THSC/TREX-2 subunits Thp1, Sac3 and Sus1 ArrayExpress

    ID: E-GEOD-56702

    Description: imal assembly of the nascent messenger ribonucleo-protein particle (mRNP), as THO/TREX and the NPC-associated THSC/TREX-2 complex. We used microarrays to analyze the global impact of THSC/TREX-2 in gene expression and found that Thp1 and Sac3 depletion has a functional impact ...

  16. Gene Expression Profiles of IL17RC+ and IL17RC- THP1 Cells OmicsDI

    ID: E-GEOD-37659

    Date Released: 05-11-2012

    Description: AMD patients led to an elevated expression of its protein and mRNA in peripheral blood as well as in the retina and choroid, suggesting that the DNA methylation pattern and expression of IL17RC may potentially serve as a biomarker for the diagnosis of AMD and likely plays a role in disease pathogenesis. Affymetrix U133 plus 2.0 GeneChip was used to detect gene expression patterns of IL17RC+ and IL17RC- THP1 cells....

  17. Macrophage Microvesicles Induce Macrophage Differentiation and miR-223 Transfer ArrayExpress

    ID: E-GEOD-41889

    Description: primary monocyte-derived macrophages (MDM) and in THP1 cells, and compare this to cells treated with GM-CSF and PMA, respectively. All experiments were done in triplicates. Primary monocytes were collected from buffy coats (BC). The freshly isolated monocytes from three donors (Mono1-3) were either treated with GM-CSF or subjected to RNA isolation. Following treatment, MVs were isolated from the GM-CSF-treated macrophage cultures. RNA was isolated from the remaining cells for profiling (GM1-3). The isolated MVs were then used to treat new BC monocytes for 24 h (BC-GMCSF-MV24). A fraction of the new BC monocytes was subjected to RNA extraction for profiling (BC1-3). For THP1 cells, they were treated with either DMSO or PMA to produce MVs. The MVs were collected and the remaining cells lyzed for RNA extraction and profiling (DMSO1-3 and PMA1-3). The collected MVs from the DMSO or PMA-treated THP1 cells were incubated with new THP1 for 24 h and designated DMSO-MV24 or PMA-MV24. We had a total of 24 samples....

  18. in vivo and in vitro study of asthma BioProject

    ID: PRJNA138225

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ene expression patterns of the LPS or HDM-treated THP1 cells compared with those from non-treated THP1 cells. And we analyzed the microarray data through clustering analysis, signaling pathway analysis and others. Overall design: Ten milliliters of peripheral blood of five mild asthma, five severe asthma and five normal subjects were centrifuged at 4000 rpm for 20 min to collect 0.4 mL of the buffy coat fraction for in vivo study. To induce an inflammatory response, for in vitro study, the THP1 cells were seeded in 12-well plates at a density of
  19. Uracil Repair - A Source of DNA Glycosylase Dependent Genome Instability BioProject

    ID: PRJNA271351

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: osaccharomyces pombe with only two UDGs, Ung1 and Thp1, as a simpler model to study functional interactions in uracil repair. We show that despite a predominance of Ung1 activity in cell extracts, both UDGs act redundantly against genomic uracil accumulation and mutations from cytosine deamination in cells. Notably, Thp1 but not Ung1-dependent repair is cytotoxic under genomic uracil stress induced by 5-fluorouracil exposure or AID expression. Also, Thp1- but not Ung1-mediated base excision is recombinogenic, accounting for mor...
  20. Detection of non-coding deletion CNVs upstream to FOXF1 [Agilent-030795] ArrayExpress

    ID: E-GEOD-39254

    Description: anscribed. Long non-coding RNAs (lncRNAs) are non-protein coding transcripts longer than 200 nucleotides and their functions remain enigmatic. We demonstrate that deletions of lncRNA genes cause a lethal lung developmental disorder, Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins (ACD/MPV), with parent of orig...


Displaying 20 of 316 results for "GLI2"