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Displaying 20 of 316 results for "GLI2"
  1. Effects of PMA on exon usage of HL60, THP-1, and U937 cells ArrayExpress

    ID: E-GEOD-20567

    Description: Myeloid leukemia cell lines HL60, THP-1, and U937 undergo macrophage-like differentiation after treatment with phorbol ester. To explore genes whose exon usage was alter...

  2. Transcription profiling of human monocytic leukemia cell line THP-1 treated with Ganoderma lucidum polysaccharides F3 ArrayExpress

    ID: E-GEOD-16014

    Description: ression associated with biological effects in THP-1 cells induced by F3, we performed a transcriptomic analysis on the THP-1 control and F3-treated THP-1 cells by oligonucleotide micro...

  3. HaCaT +GLI1/2 24/72h BioProject

    ID: PRJNA89971

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases [2007]... BioProject

    ID: PRJNA155971

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Inv(16)(p13.3;q24.3)-Encoded CBFA2T3-GLIS2 Fusion Protein As a Recurrent Lesion in 39% of Non-Infant Cases [2010]... BioProject

    ID: PRJNA155973

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. in vivo and in vitro study of asthma ArrayExpress

    ID: E-GEOD-27876

    Description: ene expression patterns of the LPS or HDM-treated THP1 cells compared with those from non-treated THP1 cells. And we analyzed the microarray data through clustering analysis, signaling pathway analysis and others. Ten milliliters of peripheral blood of five mild asthma, five severe asthma and five normal subjects were centrifuged at 4000 rpm for 20 min to collect 0.4 mL of the buffy coat fraction for in vivo study. To induce an inflammatory response, for in vitro study, the THP1 cells were seeded in 12-well plates at a density of 1 × 106...

  7. Gene Expression Profiles of IL17RC+ and IL17RC- THP1 Cells ArrayExpress

    ID: E-GEOD-37659

    Description: AMD patients led to an elevated expression of its protein and mRNA in peripheral blood as well as in the retina and choroid, suggesting that the DNA methylation pattern and expression of IL17RC may potentially serve as a biomarker for the diagnosis of AMD and likely plays a role in disease pathogenesis. Affymetrix U133 plus 2.0 GeneChip was used to detect gene expression patterns of IL17RC+ and IL17RC- THP1 cells....

  8. Comparison of gene expression changes in AML cells after SMARCA4, SMARCD2 or DPF2 knock-down ArrayExpress

    ID: E-GEOD-67923

    Description: lation. Human acute monocytic leukemia cells (THP-1, ACC 16) were lentivirally transduced with pLKO-puro vectors carrying shRNAs against SMARCA4, SMARCD2 or DPF2. As a negative control, THP-1 cells were transduced with pLKO-puro-shScr (Scrambled). All samples were prepared as biological triplicates....

  9. Genome-wide chromatin landscape of chemical-induced neural stem cell reprogramming from defined fibroblasts OmicsDI

    ID: E-GEOD-78977

    Date Released: 05-22-2016

    Description: g specific transcription factors such as Elk1 and Gli2 that are downstream of M9-induced signaling pathways bind and activate endogenous master neural genes to specify neural identity. Our study therefore provides an effective chemical approach for generating neural stem cells from mouse fibroblasts, and reveals mechanistic insights into underlying reprogramming process. Genome-wide epigenetic changes of H3K4me1, H3K4me3, H3K27me3, and H3K27ac were analyzed by CHIP-seq for tdMEFs from day 0 (ciNSLC), day 4 (D4), day 8 (D8) of M9-induced neural reprogramming, and ciNSLCs and pri-NPC....

  10. Genomic analysis of Smoothened inhibitor resistance in basal cell carcinoma OmicsDI

    ID: EGAS00001000845

    Date Released:

    Description: in the downstream Hh pathway components SUFU and GLI2, as well as novel SMO mutations that reduce sensitivity to vismodegib. The latter fall into two classes: those that activate SMO and those that directly affect the vismodegib-binding pocket. Additionally, we observe evidence of clonal selection of SMO mutations and intra-tumor heterogeneity of resistance mechanisms, which implies diverse and combinatorial strategies are required to overcome resistance....

  11. RNA-Seq analysis of Gtf2ird1 knockout epidermal tissue provides potential insights into molecular mechanisms underpinning Williams-Beuren syndrome OmicsDI

    ID: E-GEOD-81082

    Date Released: 08-05-2016

    Description: velopment including Hey1, Myf6, Myog, Dlx2, Gli1, Gli2, Lhx2, Pou3f3, Sox2, and Foxp3. We also found that the absence of GTF2IRD1 is associated with increased expression of genes involved in cellular proliferation, including growth factors consistent with the observed phenotype of extreme thickening of the epidermis. At the same time, there was a decrease in the expression of genes involved in other signalling mechanisms, including the Wnt pathway, indicating dysregulation in the complex networks necessary for epidermal differentiation an...

  12. Detection of non-coding deletion CNVs upstream to FOXF1 [Agilent-022084] OmicsDI

    ID: E-GEOD-38978

    Date Released: 05-02-2014

    Description: anscribed. Long non-coding RNAs (lncRNAs) are non-protein coding transcripts longer than 200 nucleotides and their functions remain enigmatic. We demonstrate that deletions of lncRNA genes cause a lethal lung developmental disorder, Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins (ACD/MPV), with parent of o...

  13. Expression data from Saccharomyces cerevisiae strains deleted for the THSC/TREX-2 subunits Thp1, Sac3 and Sus1 BioProject

    ID: PRJNA244325

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. THP1 derived macrophage and foam cell gene expression in presence and absence of T0901317 and RNAi analyses of LXRa/b OmicsDI

    ID: E-MTAB-1106

    Date Released: 05-03-2014

    Description: in macrophages and foam cells we treated our two, THP1 derived native and LXR-knockdown cell models either with T0901317 or vehicle control (DMSO)....

  15. NanoString miRNA profiling of THP1-differentiated macrophages treated with LPS derived from A. aggregatibacter, P. gingivalis and Pg LPS treated with cigrate smo... BioProject

    ID: PRJNA186007

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. Target miRNAs of MLL-AF9 as revealed by RNAi BioProject

    ID: PRJNA288978

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ific knockdown via siRNAs in the AML M5 cell line THP1 which harbors the corresponding t(9;11) translocation. MiRNA expression profile analyses revealed 21 differentially expressed miRNAs. Overall design: 4 samples were analyzed, each corresponding to a poo...
  17. Transcriptomics of THP-1 host cells infected with Mycobacterium tuberculosis (Mtb) BioProject

    ID: PRJNA219720

    Keywords: Transcriptome or Gene expression

    Access Type: download

  18. Structure of mRNA export factors PDB

    ID: PDB:5SUQ

    Description: ATP-dependent RNA helicase SUB2 (E.C., Tex1, Tho2, Hpr1, Mft1, and Thp2

  19. Transcriptome response after addition of individual agonists of TLR4 (MPLA) and NOD2 (MDP) receptors to THP-1 cells or its combination ArrayExpress

    ID: E-GEOD-79900

    Description: rization domain (NOD)-like receptor (NOD2) in THP-1 cells. Analysis was performed 3 hours post addition of TLR4 agonist MPLA and the NOD2 agonist MDP to THP-1 cells. The results provide the detailed molecular profile of the the genetic response to individual and combined stimulation of TLR4 and NOD2 receptors THP-1 cells...

  20. Hedgehog/GLI signalling and hormone independence in prostate cancer (PCa) cell lines ArrayExpress

    ID: E-GEOD-27231

    Description: High levels of GLI (GLI1 and GLI2) mRNA and GLI luciferase reporter activity were detected in the androgen i...

Displaying 20 of 316 results for "GLI2"