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Displaying 20 of 284 results for "FOXP1"
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  1. Med23-dependent gene expression programs in T cells ArrayExpress

    ID: E-GEOD-60779

    Description: n genes (Med23, IFNg, IL2, Egr2, c-Fos, c-Jun and Foxp1) was validated in the same RNA samples by real-time PCR. TCR induced Med23-dependent gene expression was measured after unstimulation or stimulation for 6 hr in wildtype and Med23 knockout CD4 T cells....

  2. The role of AR-associated factors in androgen signaling BioProject

    ID: PRJNA251976

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: n. We identified androgen-regulated genes, CTBP2, FOXP1 and RUNX1. These factors interact with AR ligand dependently. In order to investigate androgen-regulated gene functions in prostate cancer cells, we performed gene expression in AR-positive prostate cancer cell lines after siRNA treatment. We a...
  3. Muscleblind-like proteins regulate embryonic stem cell-specific alternative splicing and reprogramming II ArrayExpress

    ID: E-GEOD-45504

    Description: rly understood. Here, we identify the Muscleblind-like RNA binding proteins, MBNL1 and MBNL2, as conserved and direct negative regulators of a large program of AS events that are differentially regulated between ESCs and other cell types. Knockdown of MBNL proteins in differentiated cells causes switching to an ESC-like AS pattern for at least half of these AS events. Among the events is an ESC-specific AS switch in the forkhead family transcription factor FOXP1 th...

  4. Suppressio​n of MicroRNA-9 by Mutant EGFR Signaling Induces FOXP1 to Enhance Glioblasto​ma Tumorigeni​city BioProject

    ID: PRJNA232148

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Suppressio​n of MicroRNA-9 by Mutant EGFR Signaling Induces FOXP1 to Enhance Glioblasto​ma Tumorigeni​city ArrayExpress

    ID: E-GEOD-53504

    Description: The EGF-receptor (EGFR) is amplified and mutated in glioblastoma (GBM) where its common mutation, (∆EGFR, also called EGFRvIII) has a variety of act...

  6. FOXP1 inhibits cell growth and attenuates tumorigenicity of neuroblastoma OmicsDI

    ID: E-GEOD-62419

    Date Released: 10-25-2014

    Description: ights into the molecular processes occurring upon FOXP1 re-expression, we performed series of time-resolved gene expression measurements in FOXP1 and GFP transgenic neuroblastoma cell lines. Single-color gene expression profiles from 3 neuroblastoma cell lines were generated using 44K oligonucleo...

  7. of knockdowns using custom siRNA pools targeting FOXP1 exons 18 or 18b in human embryonic stem cells... OmicsDI

    ID: E-GEOD-30995

    Date Released: 04-14-2016

    Description: nt that changes the DNA binding preference of the forkhead family transcription factor FOXP1. We show that the ESC-specific isoform of FOXP1 stimulates the expression of transcription factor genes required for pluripotency including OCT4, NANOG, NR5A2 and GDF3, while concomitantly repressing genes required for ESC differentiation. Remarkably, this isoform also promotes the maintenance of ESC pluripotency and t...

  8. FOXP1 is a transcriptional Coactivator of Wnt/β-catenin signaling in Diffuse Large B-cell Lymphoma ProteomeXchange

    ID: PXD001485

    Instrument: LTQ Orbitrap Velos

    Date Released: 07-05-2016

  9. An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [AS microarray] BioProject

    ID: PRJNA155297

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: nt that changes the DNA binding preference of the forkhead family transcription factor FOXP1. We show that the ESC-specific isoform of FOXP1 stimulates the expression of transcription factor genes required for pluripotency including OCT4, NANOG, NR5A2 and GDF3, while concomitantly repressing genes required for ESC differentiation. Remarkably, this isoform also promotes the maintenance of ESC pluripotency and t...
  10. Muscleblind-like proteins regulate embryonic stem cell-specific alternative splicing and reprogramming I ArrayExpress

    ID: E-GEOD-45503

    Description: rly understood. Here, we identify the Muscleblind-like RNA binding proteins, MBNL1 and MBNL2, as conserved and direct negative regulators of a large program of AS events that are differentially regulated between ESCs and other cell types. Knockdown of MBNL proteins in differentiated cells causes switching to an ESC-like AS pattern for at least half of these AS events. Among the events is an ESC-specific AS switch in the forkhead family transcription factor FOXP1 th...

  11. Retroviral overexpression or siRNA mediated knockdown of FOXP1 in DLBCL cell lines and primary human B cells OmicsDI

    ID: E-GEOD-51382

    Date Released: 11-01-2014

    Description: the role of and target genes of the transcription factor FOXP1 in mature human B cells and in B cell non-Hodkgin lymhomas, we performed gene express...

  12. Gene expression profiling of FOXP1-silenced diffuse large B-cell lymphoma (DLBCL) cell lines OmicsDI

    ID: E-GEOD-71526

    Date Released: 12-08-2015

    Description: ntify differentially expressed genes regulated by FOXP1 in DLBCL cells via gene expression profiling of GCB-DLBCL (DB, K422) and ABC-DLBCL (OCI-Ly3, HBL-1) cell lines t...

  13. Foxp1 is a rate-limiting and essential negative regulator of Tfh cell differentiation OmicsDI

    ID: E-GEOD-50725

    Date Released: 06-03-2014

    Description: largely unknown. Here we find that transcription factor Foxp1, previously shown to be essential in maintaining T cell quiescence, is a rate-limiting and essential negative regulator of Tfh cell differentiation. Naïve CD4+ T cells constitutively express Foxp1A, and stimulation through the T cell receptor (TCR) transiently induces the expression of a sho...

  14. Elucidation of FOXP1 target genes in diffuse large B-cell lymphoma cells by ChIP-Seq OmicsDI

    ID: E-MTAB-3741

    Date Released: 11-30-2015

    Description: ChIP-Sequencing of 4 diffuse large B-cell lymphoma cell lines expressing different amounts of FOXP1 was performed in order to identify target genes...

  15. Recruitment of FOXP1 to target genes in diffuse large B-cell lymphoma (DLBCL) cells OmicsDI

    ID: E-GEOD-44243

    Date Released: 05-04-2014

    Description: Identification of FOXP1 target genes in the OCI-Ly1 DLBCL cell line by ChIP-on-chip Three replicates of the FOXP1 ChIP-on-chip wer...

  16. Transcription profiling by high throughput sequencing of Id-proteins (Id2 and Id3) gene knockout cells ArrayExpress

    ID: E-GEOD-64779

    Description: It is now well established that the E- and Id-protein axis regulates multiple steps in lymphocyte development. However, it remains unknown as to how E- and Id-proteins mechanist...

  17. Subtype Specific Addiction of the Activated B Cell Subset of Diffuse Large B Cell Lymphoma to FOXP1 OmicsDI

    ID: E-GEOD-63257

    Date Released: 01-09-2016

    Description: transcript and target gene profiling reveal that FOXP1 acts directly and indirectly by enforcing known ABC-DLBCL hallmarks, including Chronically Activated B cell receptor ...

  18. An epithelial paracrine pathway that induces an asthmatic phenotype through a neuropeptide-Y induced mechanism BioProject

    ID: PRJNA271848

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: e) and Scgb1a1-Cre:Foxp1flox/flox:Foxp4flox/flox (Foxp1/4DKO) mutants, and did larger proximal airway microarray analysis, respectively....
  19. Elucidation of FOXP1 target genes in diffuse large B-cell lymphoma cells by RNA-Seq OmicsDI

    ID: E-MTAB-3740

    Date Released: 11-30-2015

    Description: Elucidation of FOXP1 target genes by RNA-Seq of DLBCL cell lines transfected with siRNAs targeting FOXP1 expression...

  20. Posttransplant diffuse large B-cell lymphoma: new genetic findings BioProject

    ID: PRJNA285495

    Keywords: Variation

    Access Type: download


Displaying 20 of 284 results for "FOXP1"