FOXP1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 284 results for "FOXP1"
i
  1. An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [ChIP-Seq] ArrayExpress

    ID: E-GEOD-31006

    Description: nt that changes the DNA binding preference of the forkhead family transcription factor FOXP1. We show that the ESC-specific isoform of FOXP1 stimulates the expression of transcription factor genes required for pluripotency including OCT4, NANOG, NR5A2 and GDF3, while concomitantly repressing genes required for ESC differentiation. Remarkably, this isoform also promotes the maintenance of ESC pluripotency and t...

  2. MicroRNA-150 Contributes to the Proficiency of B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia by Regulating Expression of GAB1 and FOXP1 Genes... ArrayExpress

    ID: E-GEOD-49896

    Description: vel miR-150 expressed relatively higher levels of forkhead box P1 (FOXP1) and GRB2-associated binding protein 1 (GAB1), genes with 3’ UTRs having evolutionary-conserved binding sites for miR-150. High-level expression of miR-150 could repress expression of these genes, which encode proteins that may enhance B-cell receptor (BCR) signaling, a putative CLL-growth/survival signal. Also, high-level expression of miR-150 levels was a significant independent predictor of longer treatment-free-survival (TFS) or overall survival (OS), wherea...

  3. Foxp1 is a rate-limiting and essential negative regulator of Tfh cell differentiation ArrayExpress

    ID: E-GEOD-50725

    Description: largely unknown. Here we find that transcription factor Foxp1, previously shown to be essential in maintaining T cell quiescence, is a rate-limiting and essential negative regulator of Tfh cell differentiation. Naïve CD4+ T cells constitutively express Foxp1A, and stimulation through the T cell receptor (TCR) transiently induces the expression of a sho...

  4. FOXP1_CHICK UniProt:Swiss-Prot

    ID: Q58NQ4

    Description: Forkhead box protein P1 C2H2-type Fork-head

  5. An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [RNA-Seq] BioProject

    ID: PRJNA154623

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: nt that changes the DNA binding preference of the forkhead family transcription factor FOXP1. We show that the ESC-specific isoform of FOXP1 stimulates the expression of transcription factor genes required for pluripotency including OCT4, NANOG, NR5A2 and GDF3, while concomitantly repressing genes required for ESC differentiation. Remarkably, this isoform also promotes the maintenance of ESC pluripotency and t...
  6. Foxp1 is a rate-limiting and essential negative regulator of Tfh cell differentiation BioProject

    ID: PRJNA218582

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1 OmicsDI

    ID: E-GEOD-50514

    Date Released: 09-27-2013

    Description: The transcription factor FOXP1 is implicated in the pathogenesis of B-cell lymphomas through immunoglobulin hea...

  8. An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [ChIP-Seq] BioProject

    ID: PRJNA154619

    Keywords: Epigenomics

    Access Type: download

    dataset.description: nt that changes the DNA binding preference of the forkhead family transcription factor FOXP1. We show that the ESC-specific isoform of FOXP1 stimulates the expression of transcription factor genes required for pluripotency including OCT4, NANOG, NR5A2 and GDF3, while concomitantly repressing genes required for ESC differentiation. Remarkably, this isoform also promotes the maintenance of ESC pluripotency and t...
  9. Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization BioProject

    ID: PRJNA122255

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [protein binding microarray] ArrayExpress

    ID: E-GEOD-31007

    Description: nt that changes the DNA binding preference of the forkhead family transcription factor FOXP1. We show that the ESC-specific isoform of FOXP1 stimulates the expression of transcription factor genes required for pluripotency including OCT4, NANOG, NR5A2 and GDF3, while concomitantly repressing genes required for ESC differentiation. Remarkably, this isoform also promotes the maintenance of ESC pluripotency and t...

  11. The role of AR-associated factors in androgen signaling ArrayExpress

    ID: E-GEOD-58309

    Description: n. We identified androgen-regulated genes, CTBP2, FOXP1 and RUNX1. These factors interact with AR ligand dependently. In order to investigate androgen-regulated gene functions in prostate cancer cells, we performed gene expression in AR-positive prostate cancer cell lines after siRNA treatment. We a...

  12. An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [AS microarray] ArrayExpress

    ID: E-GEOD-31948

    Description: nt that changes the DNA binding preference of the forkhead family transcription factor FOXP1. We show that the ESC-specific isoform of FOXP1 stimulates the expression of transcription factor genes required for pluripotency including OCT4, NANOG, NR5A2 and GDF3, while concomitantly repressing genes required for ESC differentiation. Remarkably, this isoform also promotes the maintenance of ESC pluripotency and t...

  13. MicroRNA-150 Contributes to the Proficiency of B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia by Regulating Expression of GAB1 and FOXP1 Genes... BioProject

    ID: PRJNA215277

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. MicroRNA-150 Contributes to the Proficiency of B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia by Regulating Expression of GAB1 and FOXP1 Genes... OmicsDI

    ID: E-GEOD-49896

    Date Released: 08-08-2014

    Description: vel miR-150 expressed relatively higher levels of forkhead box P1 (FOXP1) and GRB2-associated binding protein 1 (GAB1), genes with 3’ UTRs having evolutionary-conserved binding sites for miR-150. High-level expression of miR-150 could repress expression of these genes, which encode proteins that may enhance B-cell receptor (BCR) signaling, a putative CLL-growth/survival signal. Also, high-level expression of miR-150 levels was a significant independent predictor of longer treatment-free-survival (TFS) or overall survival (OS), wherea...

  15. The forkhead transcription factor FOXP1 profile in B-cells and B-cell lymphoma cell lines OmicsDI

    ID: E-GEOD-69009

    Date Released: 08-19-2015

    Description: Expression of the forkhead transcription factor FOXP1 is essential for early B cell developm...

  16. Med23-dependent gene expression programs in T cells BioProject

    ID: PRJNA259533

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: n genes (Med23, IFNg, IL2, Egr2, c-Fos, c-Jun and Foxp1) was validated in the same RNA samples by real-time PCR. Overall design: TCR induced Med23-dependent gene expression was measured after unstimulation or stimulation for 6 hr in wildtype and Med23 knockout CD4 T cells....
  17. Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization GEMMA

    ID: 2618

    Keywords: functional genomics

    Description: Alpha-synuclein is an abundant protein implicated in synaptic function and plasticity, but the molecular mechanism of its action is not understood. Missense mutat...

  18. Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization OmicsDI

    ID: E-GEOD-19534

    Date Released: 09-08-2015

    Description: Alpha-synuclein is an abundant protein implicated in synaptic function and plasticity, but the molecular mechanism of its action is not understood. Missense mutat...

  19. The role of Foxp1/4 in lung development OmicsDI

    ID: E-GEOD-34584

    Date Released: 05-04-2014

    Description: Foxp1/4 transcription factors are conserved transcriptional repressors expressed in overlapping patterns during lung development as...

  20. An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [protein binding microarray] BioProject

    ID: PRJNA154621

    Keywords: Other

    Access Type: download


Displaying 20 of 284 results for "FOXP1"