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  1. Cannabinoid receptor double knockout mice (Cnr1 -/- /Cnr2 -/-) in CHS model GEMMA

    ID: 552

    Keywords: functional genomics

    Description: y exacerbated allergic inflammation. In contrast, fatty acid amide hydrolase deficient mice, which have increased levels of the endocannabinoid anandamide, displayed reduced allergic responses in the skin. Cannabinoid receptor antagonists exacerbated whereas receptor agonists attenuated allergic inflammation. These results demonstrate a protective role of the endocannabinoid system in contact allergy in the skin, and suggest a novel target for therapeutic intervention. Last Updated (by provider): Jun 11 2007 Contributers: Andreas Zimmer Evelyn Gaffal Thomas Tüting Lihua Wang-Eckhardt Meliha Karsak...


Displaying 1 of 1 results for "FA2H"