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Displaying 20 of 320 results for "EWSR1"
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  1. The human Ewing's Sarcoma oncoprotein EWS-FLI1 causes developmental defects in zebrafish embryos BioProject

    ID: PRJNA154077

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Ewing Sarcoma ArrayExpress

    ID: E-GEOD-36859

    Description: ysis: Ewing Sarcoma GSE36858: 5- AZA treatment of EWS cell lines Refer to individual Series...

  3. EWS/ATF1 activates Fos and induces soft tissue sarcomas [Affymetrix]. BioProject

    ID: PRJNA176040

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. A673 inducible-rescue experiment BioProject

    ID: PRJNA104529

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: A673 Ewing's sarcoma cells, with inducible EWS/FLI cDNA, harboring the EF-2-RNAi retrovirus, induced (or uninduced) for the indicated time period. Keywords: time course Overa...
  5. Targeting EWSR1-FLI1 oncogene induced protein kinase C beta abolishes Ewing sarcoma growth in vivo OmicsDI

    ID: E-GEOD-38392

    Date Released: 07-17-2012

    Description: st Ewing sarcoma. We report the identification of Protein Kinase C Beta (PRKCB) as a protein specifically and highly expressed in Ewing sarcoma as compared to other pediatric cancers. Its transcriptional activation is directly regulated by the

  6. Additional file 9: of EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3634613_D8

    Release Date: 12-15-2016

    Description: List of FUS and EWS ChIP-seq peaks assigned with a position downstream the poly(A)-signal of a target gene. (XLSX 14 kb)

  7. Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription ArrayExpress

    ID: E-GEOD-31838

    Description: Using EWS-FLI and its parental transcription factor, FLI1, we created a unique experimental system to address questions regarding the gen...

  8. Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) ArrayExpress

    ID: E-GEOD-61950

    Description: We show that EWS-FLI1, an aberrant transcription factor responsible for the pathogenesis of Ewing sarcoma, reprograms gene regulatory circuits b...

  9. EWS-WT1 Oncogene Activates a Neuronal Reprogramming Factor ASCL1 and Mediates Partial Neural Differentiation ArrayExpress

    ID: E-GEOD-53301

    Description: A chromosomal translocation fusion gene product EWS-WT1 is the defining genetic event in Desmoplastic Small Round Cell Tumor (DSRCT), a rare but aggressive tumor with a high rate ...

  10. Gene expression profiling of myxoid liposarcomas (validation set INT-B) ArrayExpress

    ID: E-GEOD-55465

    Description: FUS-CHOP and EWS-CHOP balanced translocations characterize myxoid liposarcoma which encompasses myxoid (ML) and round cell (RC) variants initial...

  11. The human Ewing's Sarcoma oncoprotein EWS-FLI1 causes developmental defects in zebrafish embryos ArrayExpress

    ID: E-GEOD-31185

    Description: The fusion oncoprotein EWS-FLI1 arises from a t(11;22)(q24;q12) chromosomal translocation and causes Ewing's Sarcoma, a malignant bone tumor. The mechani...

  12. Pharmacologic Inhibition of Epigenetic Modification Reveals Targets of Aberrant Promoter Methylation in Ewing Sarcoma ArrayExpress

    ID: E-GEOD-44934

    Description: by an 11;22 chromosomal translocation that fuses EWSR1 located at 22q12 with FLI1, coding for a member of the ETS family of transcription factors. Although genetic changes in Ewing sarcoma have been extensively researched, our understanding of the role of epigenetic modifications in this neop...

  13. Biological indicators of prognosis in Ewing's sarcoma: An emerging role for LGALS3BP BioProject

    ID: PRJNA106323

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: We create an experimental model of EWS cells that are chemoresistant and unable to give metastasis in mice and identify a molecular signature of potential prognostic ...
  14. EWS/WT1 co-operates with the loss of p53 to exert its oncogenic effects and up-regulates canonical Wnt pathway signaling ArrayExpress

    ID: E-GEOD-42649

    Description: ur (DSRCT). The translocation fuses exon 7 of the EWS gene to exon 8 of the WT1 gene (EWS/WT1). Two splice variants of EWS/WT1 exist, arising from the presence (+KTS) or absence (-KTS) of three amino acids: lysine, threonine and serine between zinc fingers...

  15. The PRC1 protein RING1B contributes to Ewing sarcoma tumorigenesis by repressing the NaV1.6 sodium channel and modulating the NF-kB pathway,... ArrayExpress

    ID: E-GEOD-71007

    Description: lecularly defined by reciprocal translocations of EWSR1 to an ETS transcription factor. The functions of EZH2 and BMI1, two proteins of the Polycomb group (PcG) of epigenetic repressors, have been previously shown to mediate ...

  16. ERG deregulation induces PIM-1 over-expression and aneuploidy in prostate epitheilial cells BioProject

    ID: PRJNA147785

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Genome-wide chromatin analysis of Ewing sarcoma (ChIP-seq) ArrayExpress

    ID: E-GEOD-61944

    Description: We show that EWS-FLI1, an aberrant transcription factor responsible for the pathogenesis of Ewing sarcoma, reprograms gene regulatory circuits b...

  18. Ewing samples and EWS-FLI-1 inhibited Ewing cell lines GEMMA

    ID: 2503

    Keywords: functional genomics

    Description: tissues characterized by specific fusions between EWS and ETS genes, is highly debated. Through gene expression analysis comparing ETs with a variety of normal tissues, we show that the profiles of different EWS-FLI1-silenced E...

  19. Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) BioProject

    ID: PRJNA262778

    Keywords: Transcriptome or Gene expression

    Access Type: download

  20. Kids First Pediatric Research Program in Susceptibility to Ewing Sarcoma Based on Germline Risk and Familial History of Cancer BioProject

    ID: PRJNA348787

    Keywords: Phenotype or Genotype

    Access Type: download

    dataset.description: Ewing sarcoma (EWS) is a deadly bone cancer that occurs in children and adolescents. Mounting evidence suggests that a genetic predisposition exis...

Displaying 20 of 320 results for "EWSR1"