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Displaying 20 of 320 results for "EWSR1"
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  1. EWS/ATF1 activates Fos and induces soft tissue sarcomas [Affymetrix] ArrayExpress

    ID: E-GEOD-41121

    Description: location, leading to the expression of a chimeric EWS/ATF1 fusion gene. However, little is known about the mechanisms underlying how EWS/ATF1 is involved in the development of CCSs. In addition, the cells of origin for CCSs remain to be determined. We generated

  2. EWS TC-71 cell lines: IGF-1R resistant ArrayExpress

    ID: E-GEOD-34027

    Description: hanisms and pathways modulated by the resistance. EWS TC-71 cell line was exposed to increasing concentration to three different anti-IGF-1R drugs (HAb AVE1642, TKI NVP-AEW541, HAb CP-751,871, cell lines named respectively as TC/AVE, TC/AEW or TC/CP) for at least six mon...

  3. EWS/ATF1 activates Fos and induces soft tissue sarcomas from neural crest-derived cells ArrayExpress

    ID: E-GEOD-41123

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  4. Transcription profiling of human Ewing sarcoma samples and EWS-FLI-1 inhibited Ewing sarcoma cell lines ArrayExpress

    ID: E-GEOD-7007

    Description: tissues characterized by specific fusions between EWS and ETS genes, is highly debated. Through gene expression analysis comparing ETs with a variety of normal tissues, we show that the profiles of different EWS-FLI1-silenced E...

  5. siRNA profiling of human GBS6 cells after EWS-POU5F1 knockdown II ArrayExpress

    ID: E-GEOD-18901

    Description: e translocation resulted in a gene fusion between EWS and POU5F1. Gene expression analysis of t(6;22) undifferentiated sarcoma cell line GBS6 transfected with POU5F1 specific siRNA to investigate the function of EWS-POU5F1. Experiment Overall Design: 6 samples are analy...

  6. A functional liaison between E2F and the aberrant ETS oncogene EWS/FLI1 in Ewing's sarcoma ArrayExpress

    ID: E-GEOD-27524

    Description: nvestigated the genomic network of the ETS fusion EWS/FLI1 in Ewing's sarcoma (ESFT) as a model of ETS-driven tumorigenesis. ChIP-Seq and transcriptional analysis identified E2F3 as a principle co-factor of EWSFLI1 defining functionally distinct gene sets. While

  7. Genome-wide chromatin analysis of Ewing sarcoma (ATAC-seq) ArrayExpress

    ID: E-GEOD-61951

    Description: We show that EWS-FLI1, an aberrant transcription factor responsible for the pathogenesis of Ewing sarcoma, reprograms gene regulatory circuits b...

  8. EWS/ATF1 activates Fos and induces soft tissue sarcomas from neural crest-derived cells [Agilent] ArrayExpress

    ID: E-GEOD-41122

    Description: location, leading to the expression of a chimeric EWS/ATF1 fusion gene. However, little is known about the mechanisms underlying how EWS/ATF1 is involved in the development of CCSs. In addition, the cells of origin for CCSs remain to be determined. We generated

  9. RNAi profiling of human Ewings sarcoma A673 Stable-Knockdown ArrayExpress

    ID: E-GEOD-4560

    Description: Ai retroviral constructs targeting the endogenous EWS/FLI fusion transcript (either EF-2-RNAi or EF-4-RNAi). Experiment Overall Design: Eight samples total. Four luc-RNAi, and four EWS/FLI knockdown constructs (two each of EF-2-RNAi or EF-4-RNAi)....

  10. Gene expression profiling of myxoid liposarcomas (training set INT-A) ArrayExpress

    ID: E-GEOD-55464

    Description: FUS-CHOP and EWS-CHOP balanced translocations characterize myxoid liposarcoma which encompasses myxoid (ML) and round cell (RC) variants initial...

  11. Correlation between gene expression responses to FUS, EWS, and TAF15 reduction and the stress granule sequestering capacity BioProject

    ID: PRJNA152231

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. pediatric sarcoma: rhabdomyosarcoma & Ewing's sarcoma BioProject

    ID: PRJNA88001

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Affymetrx U95Av2 GeneChip hybridizations, RNA extracted from primary human pediatric alveolar (aRMS) and embryonal (eRMS) rhabdomyosarcoma, plus primary pediatric Ewing's sa...
  13. hnRNPK knock down in Ewing cell line ArrayExpress

    ID: E-GEOD-60890

    Description: ranslocation between members of the FET family of RNA binding proteins and one of several ETS transcription factors, with the most common translocation being EWS-FLI1. EWS-FLI1 leads to c...

  14. Expression data from Ewing's sarcoma tumor samples ArrayExpress

    ID: E-GEOD-37371

    Description: g sarcoma a rare pediatric tumor characterized by EWSR1-ETS fusions. We performed expression profiling of both miRNA and mRNA from the same Ewing's sarcoma tumors. We propose a novel s...

  15. microRNA expression data from Ewing's sarcoma tumor samples ArrayExpress

    ID: E-GEOD-37370

    Description: g sarcoma a rare pediatric tumor characterized by EWSR1-ETS fusions. We performed expression profiling of both miRNA and mRNA from the same Ewing's sarcoma tumors. We propose a novel s...

  16. RNAi profiling by array of human Ewings carcinoma cells to down regulate EWS-FLI1 ArrayExpress

    ID: E-MEXP-2759

    Description: We report here the DNA-binding profiles for all human and mouse ETS factors, which we generated using two different methods: a high-throughput microwell-b...

  17. ERG deregulation induces PIM-1 over-expression and aneuploidy in prostate epitheilial cells ArrayExpress

    ID: E-GEOD-32481

    Description: e main ERG oncogenic fusions: TMPRSS2/ERG (tERG), EWS/ERG and FUS/ERG,. We found that all the three ERG fusions significantly up-regulate PIM-1 expression in the NIH-3T3 cell line. PIM-1 is a serine/threonine kinase frequently over-expressed in cancers of haematological and epithelial origin. We show here that tERG expression induces PIM-1 in the non-malignant prostate cell line RWPE-1, strengthening the relat...

  18. Ewing's sarcoma miRNA expression ArrayExpress

    ID: E-TABM-1100

    Description: MicroRNA profile of 34 EWS by microarray

  19. Gene expression in Ewing tumor cell lines after STEAP1 silencing ArrayExpress

    ID: E-GEOD-26422

    Description: Ewing tumors (ET) are characterized by oncogenic EWS/ETS translocations and early metastasis. STEAP1 is a membrane-bound channel protein of unkown function. While overexpressed in many cancers, STEAP1 expression is strongly restricted to m...

  20. SNP chip data of EWS ArrayExpress

    ID: E-GEOD-15696

    Description: Ewing sarcoma is one of the solid tumor that developed in children. We performed SNP-chip analysis against 27 specimens of Ewing sarcoma using Affymet...


Displaying 20 of 320 results for "EWSR1"