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Displaying 50 of 320 results for "EWSR1"
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  1. Solution structure of the RNA recognition motif of Ewing Sarcoma(EWS) protein PDB

    ID: PDB:2CPE

    Description: RNA-binding protein EWS

  2. An interaction with Ewing's sarcoma breakpoint protein EWS defines the subset of ETS factors rearranged in prostate cancer BioProject

    ID: PRJNA297431

    Keywords: Epigenomics

    Access Type: download

  3. Additional file 1: of EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3634613_D15

    Release Date: 12-15-2016

    Description: List of significant FUS binding peaks within or close (within 10 kb distance) to annotated genes. (XLSX 11 kb)

  4. RNA immunoprecipitation (RIP)-Chip analysis for EWS-bound mRNA BioProject

    ID: PRJNA138649

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Homo sapiens : EWSR1/FL1 and E2F3 regulatory targets in Ewings Sarcoma BioProject

    ID: PRJNA213583

    Keywords: genome sequencing

    Access Type: download

  6. Additional file 1: Table S1. of Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 fu... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3602915_D1

    Release Date: 12-14-2016

    Description: Top 400 DEGs analysis result. A) GO term result of DAVID analysis. B) KEGG pathway result list. (XLSX 19 kb)

  7. Regulation of exon definition and apoptosis by the Ewing's Sarcoma Protein ArrayExpress

    ID: E-GEOD-47790

    Description: The Ewing's Sarcoma Protein EWS belongs to the TET family (FUS/TLS, EWS, TAF15) of RNA and DNA...

  8. RNA immunoprecipitation (RIP)-Chip analysis for EWS-bound mRNA ArrayExpress

    ID: E-GEOD-29313

    Description: Although EWS/FLI-1 fusion protein is responsible for most Ewing’s sarcoma family tumors (ESFT), the ...

  9. Correlation between gene expression responses to FUS, EWS, and TAF15 reduction and the stress granule sequestering capacity ArrayExpress

    ID: E-GEOD-35578

    Description: nock-down of the FET-family of proteins; the FUS, EWS, and TAF15 proteins. The FET-proteins are thought to function as transcription factors, and this hypothesis is tested in the present study. Results provide important information of the genes w...

  10. Targeting EWSR1-FLI1 oncogene induced protein kinase C beta abolishes Ewing sarcoma growth in vivo BioProject

    ID: PRJNA167796

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Low-dose actinomycin D preferentially disrupts EWS-FLI1DNA binding ArrayExpress

    ID: E-GEOD-45414

    Description: Fusion of the EWS gene to FLI1 produces a fusion oncoprotein that drives an aberrant gene expression program responsible for the development of E...

  12. Regulation of FAS Exon Definition and Apoptosis by the Ewing Sarcoma Protein ArrayExpress

    ID: E-GEOD-48065

    Description: The Ewing’s sarcoma protein EWS belongs to the TET family (FUS/TLS, EWS, TAF15) of RNA and DNA...

  13. Targeting the EWS/ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma ArrayExpress

    ID: E-GEOD-72673

    Description: netically, ES are defined by balanced chromosomal EWS/ETS translocations, which give rise to chimeric proteins (EWS-ETS) that generate an oncogenic transcriptional program associated with altered epigenetic marks throughout the genome. By use of an inhibitor (JQ1) blocking BET bromodomain binding

  14. Oncogenic Fusion Protein EWS-FLI1 is a Network Hub that Regulates Alternative Splicing ArrayExpress

    ID: E-GEOD-65941

    Description: pon proteins that modulate splice site selection. EWS-FLI1 is an Ewing sarcoma (ES) oncogene with an interactome that we demonstrate to have multiple partners in spliceosomal complexes. We evaluate EWS-FLI1 upon post-transcriptional gene regulation using both exon array and RNA-seq. Genes that potentially regulate ...

  15. Gene expression profiling of human Ewing sarcoma cells after knockdown of EGR2 or EWSR1-FLI1 ArrayExpress

    ID: E-GEOD-62090

    Description: resulting transcriptional signature with that of EWSR1-FLI1-silenced Ewing sarcoma cells. In accordance with the strong EGR2-induction by EWSR1-FLI1, both genes highly significantly overlap in their transcriptional signatures. Gene-set enrichment analyses (GSEA) and DAVID (Database for Annotation, Visualisation and Integrated Di...

  16. RUNX3 Facilitates Growth of Ewing Sarcoma Cells ArrayExpress

    ID: E-GEOD-56900

    Description: . Approximately 85% of Ewing sarcomas harbor the EWS/FLI fusion protein, which arises from a chromosomal translocation, t(11:22)(q24:q12). EWS/FLI interacts with numerous lineage-essential transcription factors to maintain mesenchymal prog...

  17. EWS of Tipping Points Workshop Figshare

    ID: doi:10.6084/M9.FIGSHARE.658932.V1

    Release Date: 01-11-2016

    Description:

  18. EWS of Tipping Points Workshop Figshare

    ID: doi:10.6084/M9.FIGSHARE.658932

    Release Date: 07-04-2014

    Description:

  19. Targeting EWSR1-FLI1 oncogene induced protein kinase C beta abolishes Ewing sarcoma growth in vivo ArrayExpress

    ID: E-GEOD-38392

    Description: st Ewing sarcoma. We report the identification of Protein Kinase C Beta (PRKCB) as a protein specifically and highly expressed in Ewing sarcoma as compared to other pediatric cancers. Its transcriptional activation is directly regulated by the

  20. 5- AZA treatment of EWS cell lines BioProject

    ID: PRJNA156961

    Keywords: Transcriptome or Gene expression

    Access Type: download

  21. A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion ArrayExpress

    ID: E-GEOD-34800

    Description: nd provided new insight into oncogenesis. We used RNA-Seq to investigate samples diagnosed as small round cell tumors of bone, possibly Ewing sarcoma, but lacking the canonical EWSR1-ETS translocation. A new fusion was observed between the BCL6 co-repressor (...

  22. Expression profiling of Ewing sarcoma samples ArrayExpress

    ID: E-GEOD-34620

    Description: g sarcoma a rare pediatric tumor characterized by EWSR1-ETS fusions, is predominantly observed in populations of European ancestry. A genome-wide association study of at least 401 French ES patients compared to either 684 French or 3668 US self-described Caucasian controls consistently revealed candidate loci at ch...

  23. Homo sapiens strain:A673 cell line : EWS function in Ewing sarcoma BioProject

    ID: PRJNA174537

    Keywords: transcriptome

    Access Type: download

  24. EWS and FUS Bind a Subset of Transcribed Genes Encoding Proteins Enriched in RNA Regulatory Functions BioProject

    ID: PRJNA297201

    Keywords: Epigenomics

    Access Type: download

  25. Expression profiles of Ewing family of tumors authenticate distinct molecular entities ArrayExpress

    ID: E-GEOD-60740

    Description: differences of FET-ETS, BCOR-CCNB3, CIC-DUX4 and EWSR1-NFATc2 tumors samples with a number of other sarcomas. Unsupervised clustering of gene expression profiles fully discriminates these four molecular entities. Specific gene signatures and pathways were further validated in model cell lines. While a clear inflammatory signature characterizes EWSR1-NFATc2 tumors, BCOR-CCNB3 ...

  26. EWS siRNA knock-down in HeLa cell line ArrayExpress

    ID: E-GEOD-22929

    Description: HeLa cell line was trasfected by a EWS siRNA oligo causing knock-down of EWS or a siRNA scrambled oligo Three biological replicates were labeled in...

  27. RNA immunoprecipitation (RIP)-Chip analysis for EWS-bound mRNA OmicsDI

    ID: E-GEOD-29313

    Date Released: 06-26-2012

    Description: Although EWS/FLI-1 fusion protein is responsible for most Ewing’s sarcoma family tumors (ESFT), the ...

  28. Cotranscriptional exon skipping in the genotoxic stress response ArrayExpress

    ID: E-GEOD-21840

    Description: lternative exon inclusion by affecting elongating RNA polymerase II. We report here that various genotoxic stress inducers, including camptothecin, inhibit the interaction between EWS, an RNA polymerase II-associated factor, and YB-

  29. EWS siRNA knock-down in HeLa cell line BioProject

    ID: PRJNA127931

    Keywords: Transcriptome or Gene expression

    Access Type: download

  30. Homo sapiens strain:TTC-466 cell line : EWS/ERG function in Ewing sarcoma BioProject

    ID: PRJNA213798

    Keywords: transcriptome

    Access Type: download

  31. Differences between NOR1 and EWS/NOR1 BioProject

    ID: PRJNA106887

    Keywords: Transcriptome or Gene expression

    Access Type: download

  32. Expression profiling of Ewing sarcoma samples BioProject

    ID: PRJNA151293

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: g sarcoma a rare pediatric tumor characterized by EWSR1-ETS fusions, is predominantly observed in populations of European ancestry. A genome-wide association study of at least 401 French ES patients compared to either 684 French or 3668 US self-described Caucasian controls consistently revealed candidate loci at chromosomes 1
  33. Transcription profiling of human NOR1- and EWS/NOR1-overexpressing 293 cells ArrayExpress

    ID: E-GEOD-11185

    Description: ferences between NOR1 and its fusion gene product EWS/NOR1, we compared the gene expression profiles of NOR1- and EWS/NOR1-overexpressing 293 cells. Experiment Overall Design: We e...

  34. Gene expression profiling of human Ewing sarcoma cells after knockdown of EGR2 or EWSR1-FLI1. BioProject

    ID: PRJNA263177

    Keywords: Transcriptome or Gene expression

    Access Type: download

  35. Homo sapiens strain:A673 cell line : EWS/FLI function in Ewing sarcoma BioProject

    ID: PRJNA176544

    Keywords: transcriptome

    Access Type: download

  36. An interaction with Ewing's sarcoma breakpoint protein EWS defines the specific oncogenic mechanism of ETS factors rearranged in prostate cancer BioProject

    ID: PRJNA321758

    Keywords: Transcriptome or Gene expression

    Access Type: download

  37. EWS-Fli and LNC regulated genes in comparison to GFP samples BioProject

    ID: PRJNA259885

    Keywords: Transcriptome or Gene expression

    Access Type: download

  38. Transcription profiling of human pediatric alveolar (aRMS) and embryonal (eRMS) rhabdomyosarcoma, plus primary pediatric Ewings sarcoma (EWS) ArrayExpress

    ID: E-GEOD-967

    Description: Affymetrx U95Av2 GeneChip hybridizations, RNA extracted from primary human pediatric alveolar (aRMS) and embryonal (eRMS) rhabdomyosarcoma, plus primary pediatric Ewing's sa...

  39. EWS TC-71 cell lines: IGF-1R resistant BioProject

    ID: PRJNA148069

    Keywords: Transcriptome or Gene expression

    Access Type: download

  40. The effects of chimeric EWS/ETS protein in human mesenchymal progenitor cells (MPCs). BioProject

    ID: PRJNA101871

    Keywords: Transcriptome or Gene expression

    Access Type: download

  41. Transcription profiling of human mesenchymal progenitor stem cells overexpressing EWS/ETS protein ArrayExpress

    ID: E-GEOD-8665

    Description: We have examined the biological effect of EWS/ETS in human MPCs using UET-13 cells that are obtained by prolonging the lifespan of human bone marrow stromal cells using the ...

  42. EWS/ATF1 activates Fos and induces soft tissue sarcomas from neural crest-derived cells [Agilent]. BioProject

    ID: PRJNA176041

    Keywords: Transcriptome or Gene expression

    Access Type: download

  43. Homo sapiens : LSD1 inhibitor HCI-2509 and gene expression in Ewing sarcoma (A673) BioProject

    ID: PRJNA213645

    Keywords: transcriptome

    Access Type: download

    dataset.description: EWS/ERG function in Ewing sarcoma
  44. Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency Figshare

    ID: doi:10.6084/M9.FIGSHARE.1486425

    Release Date: 03-11-2016

    Description:

  45. Differential gene expression in GBS6 cells after EWS-POU5F1 knockdown BioProject

    ID: PRJNA113551

    Keywords: Transcriptome or Gene expression

    Access Type: download

  46. Gene expression profiling of human Ewing sarcoma cells after knockdown of EGR2 or EWSR1-FLI1. OmicsDI

    ID: E-GEOD-62090

    Date Released: 08-19-2015

    Description: resulting transcriptional signature with that of EWSR1-FLI1-silenced Ewing sarcoma cells. In accordance with the strong EGR2-induction by EWSR1-FLI1, both genes highly significantly overlap in their transcriptional signatures. Gene-set enrichment analyses (GSEA) and DAVID (Database for Annotation, Visualisation and Integrated Di...

  47. Additional file 2: of EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3634613_D12

    Release Date: 12-15-2016

    Description: List of significant EWS binding peaks within or close (within 10 kb distance) to annotated genes. (XLSX 15 kb)...

  48. Additional file 7: of EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3634613_D4

    Release Date: 12-15-2016

    Description: d on microarray data of genes presented with FUS, EWS, FUS and EWS, and Ac-H3K9 ChIP-seq peaks. (XLS 70 kb)...

  49. A673 Stable-Knockdown BioProject

    ID: PRJNA104527

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Ai retroviral constructs targeting the endogenous EWS/FLI fusion transcript (either EF-2-RNAi or EF-4-RNAi). Keywords: Expression analysis of RNAi knockdown of endogenous EWS/FLI Overall design: Eight samples total. Four luc-RNAi, and four EWS
  50. SNP chip data of EWS BioProject

    ID: PRJNA116647

    Keywords: Variation

    Access Type: download


Displaying 50 of 320 results for "EWSR1"