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Displaying 20 of 692 results for "DNM2"
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  1. Do Airway Epithelium Air-liquid Cultures Represent the In Vivo Airway Epithelium Transcriptome? ArrayExpress

    ID: E-GEOD-18637

    Description: , while brushed cells had increased expression of cytoskeletal organization and humoral immune response genes. Overall, ALI cells are a good representation of the in vivo airway epithelial transcriptome, but for some biologic questions, the differences in the in vitro vs in vivo environments need to be considered. Affymetrix arrays were used to assess the gene expression of large airway cells cultured in vitro at air-liquid interface (12 samples) and large airway epithelial cells obtained by fiberoptic bronchoscopy of 20 healthy nonsmokers. *** Air-liquid interface Samples not provided in this Series. ***...

  2. Gene expression profiling in bone-marrow-derived neutrophils of lcn2 deficient mouse BioProject

    ID: PRJNA188072

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: lin 24p3 (24p3) is a neutrophil secondary granule protein. 24p3 is also a siderocalin, which binds several bacterial siderophores. It was therefore proposed that synthesis and secretion o...
  3. The Atoh1 targetome in murine postnatal cerebellum ArrayExpress

    ID: E-GEOD-22111

    Description: iation, migration, cell adhesion, metabolism, and cytoskeletal organization by recognizing a novel 10 nucleotide Atoh1 E-Box associated motif (AtEAM). This Atoh1 “targetome” is not only a resource for studies aimed at understanding the molecular mechanisms involved in cerebellar development, but our integrated approach provides a framework for future in vivo studies of transcription factors and their targetomes. Examination of RNA-seq WT and null expression data (2 reps each), 2 different histone modifications (2 rep each) and IgG control, and Atoh1 DNA-binding (2 reps each) and control in the developing cerebellum...

  4. MiRNA expression profiling in bone-marrow-derived neutrophils of lcn2 deficient mouse BioProject

    ID: PRJNA188073

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: lin 24p3 (24p3) is a neutrophil secondary granule protein. 24p3 is also a siderocalin, which binds several bacterial siderophores. It was therefore proposed that synthesis and secretion o...
  5. Immunopurification results of cytoskeletal motor proteins in S. cerevisiae ArrayExpress

    ID: E-GEOD-35343

    Description: y to identify the RNA cargoes associated with the cytoskeletal motor proteins of Saccharomyces cerevisiae. We immunopurified, via the use of integrated, C-terminal GFP and 9Myc tags, the five actomyosin motors, Myo1, Myo2, Myo3, Myo4, and M...

  6. Effect of ectotopic expression of K13 on global gene expression in HUVEC BioProject

    ID: PRJNA114995

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ma Asssociated Herpesvirus viral FLICE Inhibitory Protein K13 affected genes and cytokines in human blood vascular endothelial cells. The KSHV-encoded K13 protein is one of the few proteins to be expressed in latently-infected spindl...
  7. Supplemental tables from From cytoskeletal dynamics to organ asymmetry: a nonlinear, regulative pathway underlies left–right patterning Figshare

    ID: doi:10.6084/M9.FIGSHARE.4028877.V1

    Release Date: 10-14-2016

    Description: Supplementary Table 1: Effects of mRNA and protein injection on Nodal laterality and organ situs and the degree of repair of incorrect laterality; Supplementary Table

  8. The effect of dietary CLA on mammary tumorigenesis OmicsDI

    ID: E-GEOD-13553

    Date Released: 03-27-2012

    Description: e performed for the detection of AKT, c-Src, ERK1/2, and Cdc24. CLA significantly increased tumor burden (p<0.1) independent of an increase in oncogenic signaling. Mammary gland whole mounts indicated a loss of mammary adipose and extensive epithelial expansion in CLA-treated animals. Microarray analysis indicated a significant reduction in cytoskeletal related genes with at least a two-fold decrease in five out of six CLA-fed animals compared to untreated controls. Reduction of Cdc42, a key regulator of cell adhesion and cytoskeletal arrange...

  9. Dog tear film proteome in-depth analysis OmicsDI

    ID: PXD003124

    Date Released: 11-23-2015

    Description: pectrometry (MALDI-TOF-MS/MS) to characterize the protein components in each fraction. In total, 125 tear proteins were identified, with MCA (Major Canine Allergen), Serum albumin, UPF0557 protein C10orf119 homolog, Collagen alpha-2(I) chain, Tyrosine -protein kinase Fer, Keratine type II cytoskeletal, Beta-crystallin B2, Interleukin-6 and Desmin occuring as the most confident ones with the highest scores. The results showed that the proteomic strategy used in this study was successful in the analys...

  10. Myocardin-related Transcription Factors Are Required for Skeletal Muscle Development OmicsDI

    ID: E-GEOD-84063

    Date Released: 08-06-2016

    Description: al role in the regulation of actin expression and cytoskeletal dynamics. Stimuli that promote actin polymerization allow for shuttling of MRTFs to the nucleus where they activate serum response factor (SRF), a regulator of actin and other

  11. MiRNA expression profiling in bone-marrow-derived neutrophils of lcn2 deficient mouse OmicsDI

    ID: E-GEOD-43890

    Date Released: 06-02-2014

    Description: lin 24p3 (24p3) is a neutrophil secondary granule protein. 24p3 is also a siderocalin, which binds several bacterial siderophores. It was therefore proposed that synthesis and secretion o...

  12. The role of sepsis in the development of limb muscle weakness in a porcine ICU model ArrayExpress

    ID: E-GEOD-33037

    Description: pression in genes regulating heat shock proteins, cytoskeletal & sarcomeric and oxidative stress response were also apparent. Therefore, it appears that sepsis has an additive deleterious role in acute quadriplegic myopathy. Sepsis-induced molecular mechanisms involving chemokine/innate immunity and heat shock proteins are forwarded as probable mechanisms underlying the decreased force generating capacity. Conclusions : This sepsis had significant effect on biceps femoris muscle force-generation capacity but not on fiber size. However, significant differences were observed between the MV and MV+SEP in the transcriptional regulation of an increased expression of genes involved in...

  13. Determination of Phosphorylation Sites in the DivIVA Protein of Streptomyces coelicolor by Targeted LC-MS/MS OmicsDI

    ID: PXD000095

    Date Released: 08-05-2013

    Description: polar growth and branching by phosphorylating the cytoskeletal protein DivIVA. Previous MALDI-TOF analysis of DivIVA showed that a large 7.2 kDa tryptic peptide was multiply phosphorylated. To aid localization of the phosp...

  14. Complex of InlC of Listeria monocytogenes and human Tuba C-terminal SH3 domain PDB

    ID: PDB:4CC4

    Description: INLC PROTEIN, DYNAMIN-BINDING PROTEIN

  15. Stem cell factor programs the mast cell activation phenotype BioProject

    ID: PRJNA152645

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: nce of altered signals regulating calcium flux or protein kinase C, but of ineffective cytoskeletal reorganization, with evidence implicating a down-regulation of expression of the Src kinase Hck. Collectively, these findings demonstrate a major role for SCF in the homeostatic control of mast cell activation with potential relevance to mast cell-driven disease and the development of novel approaches for the treatment of allergic disorders. Overall design: Mouse bone marrow-derived mast cells were treated with IL3 or IL3+SCF. Six replicates each....
  16. Quantitative real-time RT-PCR analysis of HEK293 cells stably transfected with PRL-1 (PTP4A1) or empty pcDNA4 vector control ArrayExpress

    ID: E-GEOD-42587

    Description: The protein tyrosine phosphatase PRL-1 (Gene Symbol: PTP4A1) has been identified as an important oncogene with roles in promoting cell...

  17. Analysis of the Candida albicans phosphoproteome OmicsDI

    ID: PXD001844

    Date Released: 03-25-2015

    Description: tants lacking different kinases, it is clear that protein phosphorylation plays an important role in the regulation of these pathways. Here, we present a qualitative analysis of the phosphoproteome of C. albicans hyphae. We identified 19,590 unique peptides that corresponded to 15,906 unique phosphosites on 2,896 proteins. The ratios of serine, threonine and tyrosine phosphosites were 80.01%, 18.11%, and 1.81%, respectively. The majority of proteins (2,111) contained at least two detected phosphorylation sites. Consistent with findings in other fungi, cytoskeletal proteins were amon...

  18. SAGE libraries from cell bodies and axons of NGF-differentiated sympathetic neurons ArrayExpress

    ID: E-GEOD-13788

    Description: unctions. In neurons, mRNA trafficking and local protein translation in dendrites provides an important mechanism that mediates synaptic development and plasticity. The significance of mRNA targeting and protein synthesis in axons, however, is still unclear. Only a small number of transcripts have been identified in axo...

  19. Global microarray analysis of changes of gene expression in the epidermis of K14-caSmad1 mice OmicsDI

    ID: E-GEOD-50578

    Date Released: 06-03-2014

    Description: Bone morphogenetic protein (BMP) signalling plays a key role in the control of skin development and postnatal remodelling by regulating keratinocyte p...

  20. Gene expression profiling in bone-marrow-derived neutrophils of lcn2 deficient mouse OmicsDI

    ID: E-GEOD-43889

    Date Released: 04-03-2014

    Description: lin 24p3 (24p3) is a neutrophil secondary granule protein. 24p3 is also a siderocalin, which binds several bacterial siderophores. It was therefore proposed that synthesis and secretion o...


Displaying 20 of 692 results for "DNM2"