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Displaying 20 of 1,893 results for "COTL1"
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  1. Crystal Structure of M. tuberculosis ClpP1P2 bound to ADEP and agonist PDB

    ID: PDB:4U0G

    Description: ATP-dependent Clp protease proteolytic subunit 2 (E.C.3.4.21.92), ATP-dependent Clp protease proteolytic subunit 1

  2. ClpNS with fragments PDB

    ID: PDB:1R6Q

    Description: ATP-dependent Clp protease ATP-binding subunit clpA, ATP-dependent Clp protease adaptor protein

  3. Transcription profiling of rat liver samples from individuals subjected to burn injury or cecal ligation and puncture ArrayExpress

    ID: E-GEOD-1781

    Description: for each of the three conditions: Sham-Sham, Sham-CLP and burn-CLP. Liver samples were collected from the rats and the total RNA was analyzed on a Affymetrix RAE230A chip. No technical replicates were included in the study...

  4. crystal structure of the active form of the proteolytic complex clpP1 and clpP2 PDB

    ID: PDB:5E0S

    Description: ATP-dependent Clp protease proteolytic subunit 2 (E.C.3.4.21.92), ATP-dependent Clp protease proteolytic subunit 1

  5. Differential Expression of microRNAs following activated protein C treatment in a rat model of septic shock OmicsDI

    ID: E-GEOD-34790

    Date Released: 01-02-2015

    Description: on and end organ failure, events modulated by the Protein C pathway. MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional regulation of gene transcription yet their role in sepsis remains poorly defined. We hypothesized that aPC selectively alters the expression of specific miR...

  6. Expression profiling of early lymphoid progenitors deficient for Ebf1 and Foxo1 BioProject

    ID: PRJNA178539

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: t at the level of the common lymphoid progenitor (CLP). Both mouse strains display the existance of LY6D+ CLPs but a marked/complete lack of proB cells. To investigate similarities of the developmental defects observed we generated gene expression profiles from bo...
  7. Profiling circulating microRNA expression in experimental sepsis by cecal ligation and puncture ArrayExpress

    ID: E-GEOD-47094

    Description: perimental sepsis by cecal ligation and puncture (CLP), the whole blood samples were obtained from C57BL/6 mice at 4, 8, and 24 h following CLP for miRNA expression analysis using a miRNA array (The Mouse & Rat miRNA OneArray® v3). Br...

  8. Transcription profiling of mouse hematopoietic cells (GMP, CMP, CLP and HSC), FACS sorted from wild type and Mll-AF9 knock-ins OmicsDI

    ID: E-GEOD-10627

    Date Released: 06-10-2011

    Description: mong four types of hematopoietic cells (GMP, CMP, CLP and HSC), FACS sorted from wild type and Mll-AF9 knock-in mice. The goal was to identify genes differentially expressed in each Mll-AF9 cell type compared to the corresponding wild type cells....

  9. The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor BioProject

    ID: PRJNA263871

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: 3 was required in the common lymphoid progenitor (CLP), and was essential for the differentiation of CLP, a bone marrow cell population that gives rise to all known ILC lineages. Clonal differentiation studies revealed that CXCR6+ cells within the CLP population differentiate into all ILC lineages but not T- and B-cells. We further show that NFIL3 governs ILC development by directly regulating expression of the transcription factor TOX. These findings establish that NFIL3 directs the differentiation...
  10. Transcription profiling of mouse models of sepsis cecal ligation and puncture and tracheal instillation of P. aeruginosa reveals bcl-2 overexpression ... OmicsDI

    ID: E-GEOD-5811

    Date Released: 03-27-2012

    Description: ding bcl2L11 (bim), bcl-2L2 (bcl-w), bmf, and mcl-1. Sepsis in bcl-2 transgenic animals resulted in alteration of RNA abundance for only a single gene, ceacam1. Conclusion: These findings are consistent with sepsis-induced alterations in the balance of pro- and anti-apoptotic transcriptional networks. In addition, our data suggest that the ability of bcl-2 overexpression to improve survival in sepsis in this model is related in part to prevention of sepsis-induced alterations in spleen transcriptional responses. Experiment Overall Design: To determine the splenic response in these lethal models of CLP and Pseudomonas pneumonia, microarray analysis was performed on each spleen harvested from wild-type animals 6 hours after CLP or tracheal instillation of bacteria. The responses of the CLP or Pseudomonas spleens were compared concurrently to those of the wild-type controls, sham laparotomy and tracheal instillation of saline, respectively. This study was repeated in animals overexpressing bcl-2. Thus, the splenocyte effect of sepsis secondary to CLP (n=6) or Pseudomonas pneumonia (n=5) could be determined compared to their controls (n=6 and 5, respectively), and the effect of bcl-2 overexpression in turn also could be determined in both CLP (n=5) and pneumonia models (n=5) compared to controls (n=5 and...

  11. Transcription profiling of mouse hematopoietic cells (GMP, CMP, CLP and HSC), FACS sorted from wild type and Mll-AF9 knock-ins ArrayExpress

    ID: E-GEOD-10627

    Description: mong four types of hematopoietic cells (GMP, CMP, CLP and HSC), FACS sorted from wild type and Mll-AF9 knock-in mice. The goal was to identify genes differentially expressed in each Mll-AF9 cell type compared to the corresponding wild type cells....

  12. The 8q24 cleft lip susceptibility locus is a remote Myc enhancer required for normal face morphology OmicsDI

    ID: E-GEOD-52974

    Date Released: 05-30-2014

    Description: eased risk of non-syndromic cleft lip and palate (CLP) in humans, but the genes and pathways involved in this genetic susceptibility have remained elusive. With a large series of rearrangements engineered over the syntenic mouse region, we showed th...

  13. ILC progenitor CEL-seq BioProject

    ID: PRJNA305531

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: uding NK cells, and the CD25- ILC2-restricted Sca-1+ CILP. We mapped the transcriptional changes that occur in ILC progenitor commitment identifying new regulatory factors and provide a map for early ILC differentiation. Finally, we mapped the subsequent transc...
  14. CD34+DNAMbrightCXCR4+ CLP mobilized in chronic inflammation BioProject

    ID: PRJNA285952

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. Comprensión lectora y rendimiento académico en estudiantes del primer grado de secundaria de la isntitución educativa "Emma Dettman" - Callao Zenodo

    ID: doi:10.5281/ZENODO.20832

    Release Date: 07-20-2015

    Description: riables: Sexo, Edad, Grado, Sección, Rendimiento CLP, Total CLP, Comprensión lectora, Rendimiento académico, y 124 casos....

  16. Differential protein expression by Porphyromonas gingivalis in response to secreted epithelial cell components BioProject

    ID: PRJNA93359

    Keywords: Other

    Access Type: download

  17. The Mycobacterium tuberculosis Rv2745c Plays an Important Role in Responding to Redox Stress BioProject

    ID: PRJNA242600

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: The Rv2745c (clgR) gene encodes a Clp protease gene regulator that is induced in response to a variety of stress conditions and potentially plays a role in Mtb patho...
  18. Single cell analysis of the Common Lymphoid Progenitor compartment reveals functional and molecular heterogeneity ArrayExpress

    ID: E-GEOD-19142

    Description: ells also expressed a higher level of the surface protein LY6D providing an additional tool for the analysis of early lymphoid development. These data suggest that the classical CLP compartment composes a mixture of cells with more or less restricted lineage potentials opening new possibilities to investigate early hematopoiesis. Two newly identified subpopulations of common lymphoid progenitors (CLP), hereafter called CLP_RAGhigh and CLP_RAGlow, have been sorted in 2 replicates. RNA was extracted from 2,000 purified adult BM cells using the RNAeasy microkit. RNA was labeled and amplified by dual amplification and hybridized to Affymetrix microarray MOE430_2, according to AffymetrixTM GeneChip Expression Analysis Technical Manual. Probe level expression values were calculated using the RMA algorithm....

  19. Surviving Sepsis: bcl-2 Overexpression Modulates Splenocyte Transcriptional Responses in vivo BioProject

    ID: PRJNA97191

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ding bcl2L11 (bim), bcl-2L2 (bcl-w), bmf, and mcl-1. Sepsis in bcl-2 transgenic animals resulted in alteration of RNA abundance for only a single gene, ceacam1. Conclusion: These findings are consistent with sepsis-induced alterations in the balance of pro- and anti-apoptotic transcriptional networks. In addition, our data suggest that the ability of bcl-2 overexpression to improve survival in sepsis in this model is related in part to prevention of sepsis-induced alterations in spleen transcriptional responses. Keywords: Sepsis, bcl-2, wildtype, spleen, RNA expression, microarray Overall design: To determine the splenic response in these lethal models of CLP and Pseudomonas pneumonia, microarray analysis was performed on each spleen harvested from wild-type animals 6 hours after CLP or tracheal instillation of bacteria. The responses of the CLP or Pseudomonas spleens were compared concurrently to those of the wild-type controls, sham laparotomy and tracheal instillation of saline, respectively. This study was repeated in animals overexpressing bcl-2. Thus, the splenocyte effect of sepsis secondary to CLP (n=6) or Pseudomonas pneumonia (n=5) could be determined compared to their controls (n=6 and 5, respectively), and the effect of bcl-2 overexpression in turn also could be determined in both CLP (n=...
  20. Host Responses to Sepsis Vary in Different Low-Lethality Murine Models OmicsDI

    ID: E-GEOD-55238

    Date Released: 06-03-2014

    Description: The CS and CLP murine models of intra-abdominal sepsis have unique transcriptomic respones 2 hrs, 1 and 3 days after sepsis...


Displaying 20 of 1,893 results for "COTL1"