COTL1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 1,893 results for "COTL1"
i
  1. Expression data from WT, HEB-KO and E2A-KO LY6D- CLP cells OmicsDI

    ID: E-GEOD-27402

    Date Released: 12-06-2011

    Description: The E-protein transcription factors E2A and HEB play important roles at several stages of hematopoiesis. However, the exact mechanism for...

  2. Transcription profiling by array of Mycobacterium tuberculosis clp gene regulator (ClgR) mutants ArrayExpress

    ID: E-BUGS-96

    Description: omics and targeted mutagenesis to reveal that the clp gene regulator (ClgR) of Mycobacterium tuberculosis activates the transcription of at least ten genes, including four that encode protease systems (ClpP1/C, ClpP2/C, PtrB and HtrA-like protease Rv1043c) and three that encode chaperones (Acr2, ClpB and the chaperonin Rv3269). Thus, M. tuberculosis ClgR controls a larger network of protein homeostatic and regulatory systems than ClgR in any other bacterium studied to date. We demonstrate that ClgR-regulated transcriptional activation of these systems is essential for M. tuberculo...

  3. Transcription profiling of rat liver samples from individuals subjected to burn injury or cecal ligation and puncture OmicsDI

    ID: E-GEOD-1781

    Date Released: 03-27-2012

    Description: for each of the three conditions: Sham-Sham, Sham-CLP and burn-CLP. Liver samples were collected from the rats and the total RNA was analyzed on a Affymetrix RAE230A chip. No technical replicates were included in the study...

  4. Crystal structure of the ClpP protease catalytic domain from Plasmodium falciparum PDB

    ID: PDB:2F6I

    Description: ATP-dependent CLP protease, putative (E.C.3.4.21.92)

  5. CRYSTAL STRUCTURE ANALYSIS OF ClpSN HETERODIMER TETRAGONAL FORM PDB

    ID: PDB:1MBV

    Description: ATP-Dependent clp Protease ATP-Binding Subunit clp A/Protein yljA

  6. Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. BioProject

    ID: PRJNA173022

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: in C57Bl/6J mice by cecal ligation and puncture (CLP), followed 6 hours later by an intravenous injection of Mesenchymal Stem Cell (MSC) or saline. Twenty-eight hours after CLP, plasma, bronchoalveolar lavage (BAL) fluid and tissues were collected for analyses. Total RNA ...
  7. Expression data from WT, HEB-KO and E2A-KO LY6D- CLP cells ArrayExpress

    ID: E-GEOD-27402

    Description: The E-protein transcription factors E2A and HEB play important roles at several stages of hematopoiesis. However, the exact mechanism for...

  8. etic stem cells (HSC) early B lineage stages(MLP, CLP, Fr.A, Fr.B) to identify coordinately regulated gene as cells progress down the B cell development pathway... ArrayExpress

    ID: E-MEXP-559

    Description: re prepared from four early B lineage stages(MLP, CLP, Fr.A, Fr.B) from mouse bone marrow, and microarrays were done to identify sets of genes that were coordinately regulated as cells progressed down the B cell development pathway....

  9. CRYSTAL STRUCTURE ANALYSIS OF ClpSN WITH TRANSITION METAL ION BOUND PDB

    ID: PDB:1MBX

    Description: ATP-Dependent clp Protease ATP-Binding Subunit clp A/Protein yljA

  10. The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor ArrayExpress

    ID: E-GEOD-62337

    Description: 3 was required in the common lymphoid progenitor (CLP), and was essential for the differentiation of CLP, a bone marrow cell population that gives rise to all known ILC lineages. Clonal differentiation studies revealed that CXCR6+ cells within the CLP population differentiate into all ILC lineages but not T- and B-cells. We further show that NFIL3 governs ILC development by directly regulating expression of the transcription factor TOX. These findings establish that NFIL3 directs the differentiation...

  11. Crystal structure of the mutant of ClpP E137A from Staphylococcus aureus PDB

    ID: PDB:4EMP

    Description: ATP-dependent Clp protease proteolytic subunit (E.C.3.4.21.92)

  12. The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor OmicsDI

    ID: E-GEOD-62337

    Date Released: 10-20-2014

    Description: 3 was required in the common lymphoid progenitor (CLP), and was essential for the differentiation of CLP, a bone marrow cell population that gives rise to all known ILC lineages. Clonal differentiation studies revealed that CXCR6+ cells within the CLP population differentiate into all ILC lineages but not T- and B-cells. We further show that NFIL3 governs ILC development by directly regulating expression of the transcription factor TOX. These findings establish that NFIL3 directs the differentiation...

  13. Crystal Structure of the clp gene regulator ClgR from Corynebacterium glutamicum PDB

    ID: PDB:3F51

    Description: clp gene regulator (ClgR)

  14. Streptococcus mutans UA159 vs. clp mutant strains ArrayExpress

    ID: E-GEOD-29871

    Description: Transcriptional profiling to investigate the roles of ClpP and ClpX of S. mutans RNA was extracted from four replicate samples of each strain of inter...

  15. Expression profiling of early lymphoid progenitors deficient for Ebf1 and Foxo1 OmicsDI

    ID: E-GEOD-41931

    Date Released: 11-09-2012

    Description: t at the level of the common lymphoid progenitor (CLP). Both mouse strains display the existance of LY6D+ CLPs but a marked/complete lack of proB cells. To investigate similarities of the developmental defects observed we generated gene expression profiles from bo...

  16. Arabidopsis thaliana comparative leaf proteomics of Clp protease mutant OmicsDI

    ID: PRD000393

    Date Released: 04-24-2013

    Description: Arabidopsis total leaf proteomics p3mutant biol replicate1 SDS-PAGE Band10, in-gel trypsin digestion LTQ Orbitrap

  17. Mesenchymal Stem Cells Reduce Inflammation while Enhancing Bacterial Clearance and Improving Survival in Sepsis BioProject

    ID: PRJNA132813

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: in C57Bl/6J mice by cecal ligation and puncture (CLP), followed 6 hours later by an intravenous injection of Mesenchymal Stem Cell (MSC) or saline. Twenty-eight hours after CLP, plasma, bronchoalveolar lavage (BAL) fluid and tissues were c...
  18. Transcription profiling by array of Mycobacterium tuberculosis clp gene regulator (ClgR) mutants OmicsDI

    ID: E-BUGS-96

    Date Released: 05-01-2014

    Description: omics and targeted mutagenesis to reveal that the clp gene regulator (ClgR) of Mycobacterium tuberculosis activates the transcription of at least ten genes, including four that encode protease systems (ClpP1/C, ClpP2/C, PtrB and HtrA-like protease Rv1043c) and three that encode chaperones (Acr2, ClpB and the chaperonin Rv3269). Thus, M. tuberculosis ClgR controls a larger network of protein homeostatic and regulatory systems than ClgR in any other bacterium studied to date. We demonstrate that ClgR-regulated transcriptional activation of these systems is essential for M. tuberculo...

  19. Host Responses to Sepsis Vary in Different Low-Lethality Murine Models ArrayExpress

    ID: E-GEOD-55238

    Description: The CS and CLP murine models of intra-abdominal sepsis have unique transcriptomic respones 2 hrs, 1 and 3 days after sepsis...

  20. Expression data from early B cell progenitors including CLP,ProB and PreB of Pax5 knockout and wild type C57Bl6 mice BioProject

    ID: PRJNA171116

    Keywords: Transcriptome or Gene expression

    Access Type: download


Displaying 20 of 1,893 results for "COTL1"