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Displaying 50 of 1,893 results for "COTL1"
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  1. COTL1_RAT UniProt:Swiss-Prot

    ID: B0BNA5

    Description: Removed Coactosin-like protein ADF-H Flexible and important for F-actin

  2. Solution structure of Human Coactosin Like Protein D123N PDB

    ID: PDB:1TMW

    Description: Coactosin-like protein

  3. Burn-CLP BioProject

    ID: PRJNA90575

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. COTL1_BOVIN UniProt:Swiss-Prot

    ID: Q2HJ57

    Description: Removed Coactosin-like protein ADF-H Flexible and important for F-actin

  5. Expression data from bone marrow CLP and B-cell progenitor subfractions. BioProject

    ID: PRJNA106999

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Serum-Mediated Responses in Normal and Transformed Oral Keratinocyte Lines ArrayExpress

    ID: E-GEOD-39376

    Description: luding in the Human Gene Expression Map and Human Protein Atlas databases, confirmed novel association to HNSCC for genes COTL1 and INSIG1 and novel poor outcome prediction for the genes CUL4B and PDGFRL. The definition of normal and aberrant serum responses in keratinocyte models therefore coupled new genes to HNSCC including with relevance to prognosis. Analysis of gene expression changes in serum-exposed normal and transformed cells relative the respective un-exposed states. Significantly differentially expressed genes were next assessed by bioinformatics processing using Gene Ontology categories and network analyses. Findings were also validated relative independent HNSCC data sets as well as transcriptomics and proteomics databases....

  7. LOX5_MESAU UniProt:Swiss-Prot

    ID: P51399

    Description: hidonate 5-lipoxygenase PLAT Lipoxygenase Calcium 1; via carbonyl oxygen; structural Calcium 2; via carbonyl oxygen; structural Calcium 2; structural Calcium 2; structural Calcium 2; vi...

  8. LOX5_RAT UniProt:Swiss-Prot

    ID: P12527

    Description: hidonate 5-lipoxygenase PLAT Lipoxygenase Calcium 1; via carbonyl oxygen; structural Calcium 2; via carbonyl oxygen; structural Calcium 2; structural Calcium 2; structural Calcium 2; vi...

  9. Genes affected by Satb1 deficiency in HSC, LMPP and CLP BioProject

    ID: PRJNA193433

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. Genes affected by SFRP5 overexpression in LSK cells and CLP BioProject

    ID: PRJNA240285

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. The Mycobacterium tuberculosis Clp Gene Regulator is Required for in vitro Reactivation from Hypoxia-induced Dormancy BioProject

    ID: PRJNA270020

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS PDB

    ID: PDB:1R6O

    Description: ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein

  13. Streptococcus mutans UA159 vs. clp mutant strains BioProject

    ID: PRJNA140985

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. The Mycobacterium tuberculosis Clp Gene Regulator is Required for in vitro Reactivation from Hypoxia-induced Dormancy ArrayExpress

    ID: E-GEOD-64065

    Description: b:ΔRv2745c. Induction of clgR in Mtb did lead to Clp protease induction, indicating that clgR plays a role in differntially activating downstream genes in a condition dependent manner. Disruption of genes involved in the dosR regulon, the Enduring Hypoxia Response, lipid synthesis, and mycolic acid synthesis also occurred in the knock out, implicating clgR as a possible regulator of downstream signaling cascades that facilitate Mtb survival. There was also a differnetial response of ge...

  15. Crystal Structure of the ATP-dependent Clp Protease ClpC from Clostridium difficile PDB

    ID: PDB:3FES

    Description: ATP-dependent Clp endopeptidase

  16. The Mycobacterium tuberculosis Clp Gene Regulator is Required for in vitro Reactivation from Hypoxia-induced Dormancy OmicsDI

    ID: E-GEOD-64065

    Date Released: 01-02-2015

    Description: b:ΔRv2745c. Induction of clgR in Mtb did lead to Clp protease induction, indicating that clgR plays a role in differntially activating downstream genes in a condition dependent manner. Disruption of genes involved in the dosR regulon, the Enduring Hypoxia Response, lipid synthesis, and mycolic acid synthesis also occurred in the knock out, implicating clgR as a possible regulator of downstream signaling cascades that facilitate Mtb survival. There was also a differnetial response of ge...

  17. Genes affected by SFRP5 overexpression in LSK cells and CLP OmicsDI

    ID: E-GEOD-55646

    Date Released: 06-03-2014

    Description: microarrays were conducted with Lin- c-kitHi Sca-1+ cells and Lin- c-kitLo Sca-1Lo IL7Rα+ CLP-enriched cells derived from adult bone marrow of SFRP5-transgenic mice or their WT littermates....

  18. CRYSTAL STRUCTURE OF THE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 (CLPP1) FROM MYCOBACTERIUM TUBERCULOSIS PDB

    ID: PDB:2CE3

    Description: ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 (E.C.3.4.21.92)

  19. CRYSTAL STRUCTURE OF THE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 (CLPP1) FROM MYCOBACTERIUM TUBERCULOSIS PDB

    ID: PDB:2CBY

    Description: ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 (E.C.3.4.21.92)

  20. Structure of the ClpP subunit of the ATP-dependent Clp Protease from Coxiella burnetii PDB

    ID: PDB:3Q7H

    Description: ATP-dependent Clp protease proteolytic subunit (E.C.3.4.21.92)

  21. Crystal Structure of ATP-dependent Clp protease subunit P from Francisella tularensis PDB

    ID: PDB:3P2L

    Description: ATP-dependent Clp protease proteolytic subunit (E.C.3.4.21.92)

  22. Expression data from WT, HEB-KO and E2A-KO LY6D- CLP cells BioProject

    ID: PRJNA137263

    Keywords: Transcriptome or Gene expression

    Access Type: download

  23. Genes affected by SFRP5 overexpression in LSK cells and CLP ArrayExpress

    ID: E-GEOD-55646

    Description: microarrays were conducted with Lin- c-kitHi Sca-1+ cells and Lin- c-kitLo Sca-1Lo IL7Rα+ CLP-enriched cells derived from adult bone marrow of SFRP5-transgenic mice or their WT littermates....

  24. Serum-Mediated Responses in Normal and Transformed Oral Keratinocyte Lines BioProject

    ID: PRJNA170821

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: luding in the Human Gene Expression Map and Human Protein Atlas databases, confirmed novel association to HNSCC for genes COTL1 and INSIG1 and novel poor outcome prediction for the genes CUL4B and PDGFRL. The definition of normal and aberrant serum responses in keratinocyte models therefore coupled new genes to HNSCC including with relevance to prognosis. Overall design: Analysis of gene expression changes in serum-exposed normal and transformed cells relative the respective un-exposed states. Significantly differentially expressed genes were next assessed by bioinformatics processing using Gene Ontology categories and network analyses. Findings were also validated relative independent HNSCC data sets as well as transcriptomics and proteomics databases....
  25. IL7R: WT vs mutant in vitro and in vivo ArrayExpress

    ID: E-GEOD-51211

    Description: ndidate genes downstream of IL7R-INS in vitro KSL/CLP and in vivo (depicted as B-neoplasm, Notch-T-ALL, or myeloid disorder) in comparison to WT. Five-condition experiment: WT-KSL vs. INS-KSL cells; WT-

  26. Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. OmicsDI

    ID: E-GEOD-40180

    Date Released: 06-02-2014

    Description: in C57Bl/6J mice by cecal ligation and puncture (CLP), followed 6 hours later by an intravenous injection of Mesenchymal Stem Cell (MSC) or saline. Twenty-eight hours after CLP, plasma, bronchoalveolar lavage (BAL) fluid and tissues were collected for analyses. Total RNA ...

  27. Mesenchymal Stem Cells Reduce Inflammation while Enhancing Bacterial Clearance and Improving Survival in Sepsis OmicsDI

    ID: E-GEOD-24357

    Date Released: 06-26-2012

    Description: in C57Bl/6J mice by cecal ligation and puncture (CLP), followed 6 hours later by an intravenous injection of Mesenchymal Stem Cell (MSC) or saline. Twenty-eight hours after CLP, plasma, bronchoalveolar lavage (BAL) fluid and tissues were c...

  28. Genes affected by Satb1 deficiency in HSC, LMPP and CLP ArrayExpress

    ID: E-GEOD-45299

    Description: microarrays were conducted with Lin- c-kitHi Sca-1+ Flt3- HSC-enriched cells, Lin- c-kitHi Sca-1+ Flt3+LMPP-enriched cells, and Lin- c-kitLo Sca-1Lo IL7Rα+ CLP-enriched cells derived from E18.5 FL of Satb1-null mice or their WT littermates....

  29. THE 3.0 A RESOLUTION STRUCTURE OF CASEINOLYTIC CLP PROTEASE 1 FROM MYCOBACTERIUM TUBERCULOSIS PDB

    ID: PDB:2C8T

    Description: ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 (E.C.3.4.21.92)

  30. Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1 PDB

    ID: PDB:2PKT

    Description: PDZ and LIM domain protein 1

  31. Crystal Structure of Stabilin-1 Interacting Chitinase-Like Protein, SI-CLP PDB

    ID: PDB:3BXW

    Description: Chitinase domain-containing protein 1

  32. IL7R: WT vs mutant in vitro and in vivo. OmicsDI

    ID: E-GEOD-51211

    Date Released: 06-03-2014

    Description: ndidate genes downstream of IL7R-INS in vitro KSL/CLP and in vivo (depicted as B-neoplasm, Notch-T-ALL, or myeloid disorder) in comparison to WT. Five-condition experiment: WT-KSL vs. INS-KSL cells; WT-

  33. Mesenchymal Stem Cells Reduce Inflammation while Enhancing Bacterial Clearance and Improving Survival in Sepsis ArrayExpress

    ID: E-GEOD-24357

    Description: in C57Bl/6J mice by cecal ligation and puncture (CLP), followed 6 hours later by an intravenous injection of Mesenchymal Stem Cell (MSC) or saline. Twenty-eight hours after CLP, plasma, bronchoalveolar lavage (BAL) fluid and tissues were c...

  34. The c-di-GMP Responsive Global Regulator CLP Links Cell-Cell Signaling to Virulence Gene Expression in Xanthomonas campestris PDB

    ID: PDB:3IWZ

    Description: Catabolite activation-like protein

  35. IL7R: WT vs mutant in vitro and in vivo. BioProject

    ID: PRJNA221627

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ndidate genes downstream of IL7R-INS in vitro KSL/CLP and in vivo (depicted as B-neoplasm, Notch-T-ALL, or myeloid disorder) in comparison to WT. Overall design: Five-condition experiment: WT-KSL vs. INS-KSL c...
  36. Expression profiling of early lymphoid progenitors deficient for Ebf1 and Foxo1 ArrayExpress

    ID: E-GEOD-41931

    Description: t at the level of the common lymphoid progenitor (CLP). Both mouse strains display the existance of LY6D+ CLPs but a marked/complete lack of proB cells. To investigate similarities of the developmental defects observed we generated gene expression profiles from bo...

  37. Genes affected by Satb1 deficiency in HSC, LMPP and CLP OmicsDI

    ID: E-GEOD-45299

    Date Released: 06-02-2014

    Description: microarrays were conducted with Lin- c-kitHi Sca-1+ Flt3- HSC-enriched cells, Lin- c-kitHi Sca-1+ Flt3+LMPP-enriched cells, and Lin- c-kitLo Sca-1Lo IL7Rα+ CLP-enriched cells derived from E18.5 FL of Satb1-null mice or their WT littermates....

  38. Serum-Mediated Responses in Normal and Transformed Oral Keratinocyte Lines OmicsDI

    ID: E-GEOD-39376

    Date Released: 06-02-2014

    Description: luding in the Human Gene Expression Map and Human Protein Atlas databases, confirmed novel association to HNSCC for genes COTL1 and INSIG1 and novel poor outcome prediction for the genes CUL4B and PDGFRL. The definition of normal and aberrant serum responses in keratinocyte models therefore coupled new genes to HNSCC including with relevance to prognosis. Analysis of gene expression changes in serum-exposed normal and transformed cells relative the respective un-exposed states. Significantly differentially expressed genes were next assessed by bioinformatics processing using Gene Ontology categories and network analyses. Findings were also validated relative independent HNSCC data sets as well as transcriptomics and proteomics databases....

  39. Crystal structure of ClpP in tetradecameric form from Staphylococcus aureus PDB

    ID: PDB:3STA

    Description: ATP-dependent Clp protease proteolytic subunit (E.C.3.4.21.92)

  40. Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis ArrayExpress

    ID: E-GEOD-40180

    Description: in C57Bl/6J mice by cecal ligation and puncture (CLP), followed 6 hours later by an intravenous injection of Mesenchymal Stem Cell (MSC) or saline. Twenty-eight hours after CLP, plasma, bronchoalveolar lavage (BAL) fluid and tissues were collected for analyses. Total RNA ...

  41. Expression data from WT, HEB-KO and E2A-KO LY6D- CLP cells OmicsDI

    ID: E-GEOD-27402

    Date Released: 12-06-2011

    Description: The E-protein transcription factors E2A and HEB play important roles at several stages of hematopoiesis. However, the exact mechanism for...

  42. Transcription profiling by array of Mycobacterium tuberculosis clp gene regulator (ClgR) mutants ArrayExpress

    ID: E-BUGS-96

    Description: omics and targeted mutagenesis to reveal that the clp gene regulator (ClgR) of Mycobacterium tuberculosis activates the transcription of at least ten genes, including four that encode protease systems (ClpP1/C, ClpP2/C, PtrB and HtrA-like protease Rv1043c) and three that encode chaperones (Acr2, ClpB and the chaperonin Rv3269). Thus, M. tuberculosis ClgR controls a larger network of protein homeostatic and regulatory systems than ClgR in any other bacterium studied to date. We demonstrate that ClgR-regulated transcriptional activation of these systems is essential for M. tuberculo...

  43. Transcription profiling of rat liver samples from individuals subjected to burn injury or cecal ligation and puncture OmicsDI

    ID: E-GEOD-1781

    Date Released: 03-27-2012

    Description: for each of the three conditions: Sham-Sham, Sham-CLP and burn-CLP. Liver samples were collected from the rats and the total RNA was analyzed on a Affymetrix RAE230A chip. No technical replicates were included in the study...

  44. Crystal structure of the ClpP protease catalytic domain from Plasmodium falciparum PDB

    ID: PDB:2F6I

    Description: ATP-dependent CLP protease, putative (E.C.3.4.21.92)

  45. CRYSTAL STRUCTURE ANALYSIS OF ClpSN HETERODIMER TETRAGONAL FORM PDB

    ID: PDB:1MBV

    Description: ATP-Dependent clp Protease ATP-Binding Subunit clp A/Protein yljA

  46. Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. BioProject

    ID: PRJNA173022

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: in C57Bl/6J mice by cecal ligation and puncture (CLP), followed 6 hours later by an intravenous injection of Mesenchymal Stem Cell (MSC) or saline. Twenty-eight hours after CLP, plasma, bronchoalveolar lavage (BAL) fluid and tissues were collected for analyses. Total RNA ...
  47. Expression data from WT, HEB-KO and E2A-KO LY6D- CLP cells ArrayExpress

    ID: E-GEOD-27402

    Description: The E-protein transcription factors E2A and HEB play important roles at several stages of hematopoiesis. However, the exact mechanism for...

  48. etic stem cells (HSC) early B lineage stages(MLP, CLP, Fr.A, Fr.B) to identify coordinately regulated gene as cells progress down the B cell development pathway... ArrayExpress

    ID: E-MEXP-559

    Description: re prepared from four early B lineage stages(MLP, CLP, Fr.A, Fr.B) from mouse bone marrow, and microarrays were done to identify sets of genes that were coordinately regulated as cells progressed down the B cell development pathway....

  49. CRYSTAL STRUCTURE ANALYSIS OF ClpSN WITH TRANSITION METAL ION BOUND PDB

    ID: PDB:1MBX

    Description: ATP-Dependent clp Protease ATP-Binding Subunit clp A/Protein yljA

  50. The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor ArrayExpress

    ID: E-GEOD-62337

    Description: 3 was required in the common lymphoid progenitor (CLP), and was essential for the differentiation of CLP, a bone marrow cell population that gives rise to all known ILC lineages. Clonal differentiation studies revealed that CXCR6+ cells within the CLP population differentiate into all ILC lineages but not T- and B-cells. We further show that NFIL3 governs ILC development by directly regulating expression of the transcription factor TOX. These findings establish that NFIL3 directs the differentiation...


Displaying 50 of 1,893 results for "COTL1"