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Displaying 13 of 13 results for "CD8B"
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  1. Transcription profiling of mouse small intestine intraepithelial lymphocytes (IEL) vs. TCR ab+ CD8b+ and TCR gd+ cells OmicsDI

    ID: E-GEOD-5355

    Date Released: 03-27-2012

    Description: TCR ab+ CD8aa IEL were compared to their TCR ab+ CD8b+ and TCR gd+ counterparts. Experiment Overall Design: In this study, the three IEL populations were isolated by cell sorting from a pool of IELs from 20 mice. RNA from each IEL subset was used to probe one microarray. A replicate experiment was performed on a seperate occasion using a new pool of 20 mice and three additional microarrays were used....

  2. Transcription profiling of mouse small intestine intraepithelial lymphocytes (IEL) vs. TCR ab+ CD8b+ and TCR gd+ cells ArrayExpress

    ID: E-GEOD-5355

    Description: TCR ab+ CD8aa IEL were compared to their TCR ab+ CD8b+ and TCR gd+ counterparts. Experiment Overall Design: In this study, the three IEL populations were isolated by cell sorting from a pool of IELs from 20 mice. RNA from each IEL subset was used to probe one microarray. A replicate experiment was performed on a seperate occasion using a new pool of 20 mice and three additional microarrays were used....

  3. Transcription profiling by array of mouse peripheral wild-type and HDAC1/2-null CD4+ T cells to investigate redundant and non-redundant functions of H... ArrayExpress

    ID: E-MTAB-2184

    Description: Dynamic changes in histone acetylation patterns are mediated by the activity of histone acetyltransfereases (HATs) and histone deacetylases (HDACs) an...

  4. Crystal structure of the CD8 alpha beta/H-2Dd complex PDB

    ID: PDB:3DMM

    Description: H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2 microglobulin, Synthetic peptide, T-cell surface glycoprotein CD8 alpha chain, T-cell ...

    gene.name: Cd8b, Cd8b1, Ly-3, Lyt-3, Lyt3

  5. Crystal structure of a CD8ab heterodimer PDB

    ID: PDB:2ATP

    Description: T-cell surface glycoprotein CD8 alpha chain, artifact linker, T-cell surface glycoprotein CD8 beta chain

    gene.name: Cd8b, Lyt-3, Lyt3

  6. Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB PDB

    ID: PDB:3B9K

    Description: Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB

    gene.name: Cd8b, Cd8b1, Ly-3, Lyt-3, Lyt3

  7. The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissi... ArrayExpress

    ID: E-GEOD-61195

    Description: and DNMT3B. DNA methylation was increased in CD8A/CD8B and CD4 consistent with epigenetic repression of both the CD8 and CD4 genetic loci in double negative T cells. Curiously, we show consistent increase in non-CG methylation in double negative T cells, a finding suggestive of pluripotency and previously only known to occur in embryonic stem cells and developing brain tissue. Network analyses of genes hypomethylated in double negative compared to CD4+ and CD8+ T cells indicate a strong relationship between double negative T cells and functions related to cell-cell interaction, cell adhesion, and cell activation pathways. Our data also suggest a robust pro-inflammatory epigenetic signature in double negative T cells, consistent with a transcriptional permissiveness to produce key inflammatory cytokine...

  8. Total RNA: naïve ex vivo mouse OT-1 T lymphocytes, WT vs Lck-/- (OFF) BioProject

    ID: PRJNA335378

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ective signal transduction (Lck-/-, OFF). Naïve (CD8b+, CD44low) ex vivo T cells were isolated from the superficial cervicals, axillary, brachial, mesenteric, and inguinal lymph nodes. Total RNA was extracted from the cells, labelled with Cy3, and hybridised onto an Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray. Overall design: 3 biological replicates of WT + 4 biological replicates of Lck-/- (OFF)....

  9. Microarray Analysis of Murine IEL Subsets BioProject

    ID: PRJNA96247

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: TCR ab+ CD8aa IEL were compared to their TCR ab+ CD8b+ and TCR gd+ counterparts. Keywords: Cell type comparison Overall design: In this study, the three IEL populations were isolated by cell sorting from a pool of IELs from 20 mice. RNA from each IEL subset was used to probe one microarray. A replicate experiment was performed on a seperate occasion using a new pool of 20 mice and three additional microarrays were used....

  10. The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissi... BioProject

    ID: PRJNA260497

    Keywords: Epigenomics

    Access Type: download

    dataset.description: and DNMT3B. DNA methylation was increased in CD8A/CD8B and CD4 consistent with epigenetic repression of both the CD8 and CD4 genetic loci in double negative T cells. Curiously, we show consistent increase in non-CG methylation in double negative T cells, a finding suggestive of pluripotency and previously only known to occur in embryonic stem cells and developing brain tissue. Network analyses of genes hypomethylated in double negative compared to CD4+ and CD8+ T cells indicate a strong relationship between double negative T cells and functions related to cell-cell interaction, cell adhesion, and cell activation pathways. Our data also suggest a robust pro-inflammatory epigenetic signature in double negative T cells, consistent with a transcriptional permissiveness to produce key inflammatory cytokine...

  11. The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissi... OmicsDI

    ID: E-GEOD-61195

    Date Released: 09-05-2015

    Description: and DNMT3B. DNA methylation was increased in CD8A/CD8B and CD4 consistent with epigenetic repression of both the CD8 and CD4 genetic loci in double negative T cells. Curiously, we show consistent increase in non-CG methylation in double negative T cells, a finding suggestive of pluripotency and previously only known to occur in embryonic stem cells and developing brain tissue. Network analyses of genes hypomethylated in double negative compared to CD4+ and CD8+ T cells indicate a strong relationship between double negative T cells and functions related to cell-cell interaction, cell adhesion, and cell activation pathways. Our data also suggest a robust pro-inflammatory epigenetic signature in double negative T cells, consistent with a transcriptional permissiveness to produce key inflammatory cytokine...

  12. Histology post influenza ImmPort

    ID: SDY756

    Description: Lung immunohistology post influenza infection

    molecularEntity.name: Alexa Fluor 647 anti-mouse CD8b

  13. Human Aging and CMV ImmPort

    ID: SDY736

    Description: Delineate the effect of aging from that of cytomegalovirus (CMV) infection upon relative and absolute changes in blood T cell subsets.

    molecularEntity.name: anti-human CD8b-ECD
Displaying 13 of 13 results for "CD8B"

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