Expression data from brains of BCAS1 knockout or wildtype mice BioProject

ID: PRJNA356894

Keywords: Transcriptome or Gene expression

Access Type: download

BCAS3_DROME UniProt:Swiss-Prot

ID: Q8SY41

Description: Breast carcinoma-amplified sequence 3 homolog WD 1 WD 2...

Genomic Interaction Profiles in Breast Cancer Reveal Altered Chromatin Architecture BioProject

ID: PRJNA214104

Keywords: Other

Access Type: download

CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (aCGH) BioProject

ID: PRJNA114177

Keywords: Variation

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Genomic Interaction Profiles in Breast Cancer Reveal Altered Chromatin Architecture OmicsDI

ID: E-GEOD-49521

Date Released: 09-05-2013

Description: In this study, we used IGFBP3, a gene involved in breast cancer pathogenesis, as bait in a 4C-seq experiment comparing normal breast cells (HMEC) with two breast cancer cell lines (MCF7, an ER positive cell line, and MDA-MB-231, a triple negative cell line). The IGFBP3 long-range interaction profile was substantially altered in breast cancer. Many interactions seen in normal breast cells are lost and novel interaction...

Genomic Interaction Profiles in Breast Cancer Reveal Altered Chromatin Architecture ArrayExpress

ID: E-GEOD-49521

Description: In this study, we used IGFBP3, a gene involved in breast cancer pathogenesis, as bait in a 4C-seq experiment comparing normal breast cells (HMEC) with two breast cancer cell lines (MCF7, an ER positive cell line, and MDA-MB-231, a triple negative cell line). The IGFBP3 long-range interaction profile was substantially altered in breast cancer. Many interactions seen in normal breast cells are lost and novel interaction...

CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (aCGH) ArrayExpress

ID: E-GEOD-12813

Description: n epithelial-mesenchymal transition in basal-like breast cancer Summary: Breast cancer exhibits clinical and molecular heterogeneity, where expression-profiling studies have identified five major molec...

Deep Sequence Analysis of the Relationship between Gene Expression, CpG Island Methylation, and Gene Copy Number in Breast Cancer Cells ArrayExpress

ID: E-GEOD-27003

Description: tion status simultaneously in eight commonly used breast cell lines to develop a model for how these genomic features are integrated in estrogen receptor positive (ER+) and negative breast cancer. Total mRNA sequence, gene copy number, and genomic C...

Positioning of Necrotic Lobular Intraepithelial Neoplasias within the sequence of breast carcinoma progression ArrayExpress

ID: E-GEOD-14803

Description: riant of intraepithelial lobular neoplasia of the breast composed of either uniform, generally small, cells (classic) with massive lobular distension, pleomorphic cells, signet-ring cells, or any cell type with necrosis. In contrast to classic forms of LI...

Chromosome as oncogenic organizer: functional consequences of structural mutations in breast cancer (RNA-Seq) ArrayExpress

ID: E-GEOD-57914

Description: etermining the transcriptional landscape of human breast cancers. To assess the nature of these structural mutations, we analyzed a representative sampling of the major types of breast tumor samples for detailed structural...

Synergistic activation by p38MAPK and glucocorticoid signaling mediates induction of M2-like tumor-associated macrophages expressing the novel CD20 ho... ArrayExpress

ID: E-GEOD-38171

Description: wth. Previously, we have described a special LYVE-1(+) M2 TAM subset in vitro and in vivo; gene profiling of this TAM subset identified MS4A8A as a novel TAM molecule expressed in vivo by TAM in mammary carcinoma and malignant melanoma. In vitro, Ms4a8a mRNA and MS4A8A p...

Transcription profiling by high throughput sequencing of ZNF217 chromatin occupancy in the breast cancer cell genome ArrayExpress

ID: E-GEOD-58326

Description: inc finger protein, is located at 20q13 and found amplified and overexpressed in greater than 20% of breast tumors. Current studies indicate ZNF217 drives tumorigenesis, yet the regulatory mechanisms of ZNF21...

Gene expression analysis of breast cancer cell-lines ArrayExpress

ID: E-GEOD-45732

Description: D1B histone H3 lysine 4 demethylase is frequently amplified and overexpressed in luminal breast tumors and a somatic point mutation of JARID1B leads to the gain of luminal-specific gene expression programs. Downregulation of JARID1B in luminal breast cancer cells induces the expression of basal cell-specific genes and growth arrest, which is par...

Precursor and mature microRNA expression in MCF7 cells in hypoxia ArrayExpress

ID: E-GEOD-49999

Description: ffects on microRNA biogenesis proteins. Methods: Breast cancer cell lines were exposed to hypoxia and manipulations of hypoxia inducible factor (HIF) and HIF hydroxylase activity. The effects of hypoxia on the mRNA and protein levels of enzymes involved in microRNA biogenesis (Dicer, Drosha, TARPB2, DCGR8, XPO5) was determined by RT PCR and immunoblotting. The effect of hypoxia on microRNAs was...

Transcription profiling by array time series of human MCF7 breast cancer cells treated with estradiol ArrayExpress

ID: E-GEOD-11352

Description: n receptor alpha (ERalpha) binding sites in MCF-7 breast cancer cells. We identified 1,234 high confidence binding clusters of which 94% are projected to be bona fide ERalpha binding regions. Only 5% of the mapped estrogen receptor binding sites are located within 5 kb upstream of the ...

Synergistic activation by p38MAPK and glucocorticoid signaling mediates induction of M2-like tumor-associated macrophages expressing the novel CD20 ho... BioProject

ID: PRJNA167359

Keywords: Transcriptome or Gene expression

Access Type: download

BET Bromodomain Protein BRD4 Regulates MEK Inhibitor-induced Kinome Reprogramming in Triple Negative Breast Cancer BioProject

ID: PRJNA218091

Keywords: Transcriptome or Gene expression

Access Type: download

Precursor and mature microRNA expression in MCF7 cells in hypoxia BioProject

ID: PRJNA215772

Keywords: Transcriptome or Gene expression

Access Type: download

Gene profile of breast cancers with immunohistochemical phenotypes of ER+/- and/or HER2+/- BioProject

ID: PRJNA99585

Keywords: Transcriptome or Gene expression

Access Type: download

Gene profile of breast cancers with immunohistochemical phenotypes of ER+/- and/or HER2+/- GEMMA

ID: 2649

Keywords: functional genomics

Description: d growth factors accelerate cell proliferation of breast cancer cells, and these molecules are well investigated targets for drug development and application. The mechanisms of cell prolifera...