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Displaying 20 of 607 results for "ATF1"
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  1. ChIP-chip from ex-vivo differentiated erythroblasts derived from human primary CD34+ cells BioProject

    ID: PRJNA144909

    Keywords: Epigenomics

    Access Type: download

    dataset.description: g sites for GATA, NF-E2/maf and CACCC interacting transcription factors play functionally important roles in globin and other erythroid-specific gene expression. We and others recently identified the CACCC-binding transcription factor ZBP-89 as a novel GATA-
  2. RNA-Seq experiment to identify genes regulated by ATF4 OmicsDI

    ID: E-GEOD-69308

    Date Released: 09-06-2015

    Description: Activating Transcription Factor 4 (ATF4) is a transcription

  3. Loss of Activating Transcription Factor 3 reveals a distinct gene expression program modulating cell organization during pancreatitis ArrayExpress

    ID: E-GEOD-60250

    Description: his phenomenon. Here, we define a novel role for Activating Transcription Factor 3 (ATF3) during pancreatic injury. ATF3, a key mediator in the unfolded protein response, is robustly expressed in acinar cells during pancreatitis. Targeted deletion of Atf3 altered the molecular response to injury, with Atf3-/- acinar cells maintaining cell organization in response to cerulein, a well-established inducer of pancreatitis. Characterizati...

  4. ATF3 is a novel regulator of mouse neutrophil migration. BioProject

    ID: PRJNA234095

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Expression of the activating transcription factor 3 (ATF3) gene is induced by Toll-like receptor (TLR) signalin...
  5. Genomic expression profiling of TNFalpha treated BDC2.5 diabetogenic CD4+ T Cells BioProject

    ID: PRJNA108179

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Tumor necrosis factor alpha (TNFalpha) plays an important role in immune regulation, inflammation, and autoimmunity. Chronic TNFalpha exposure ha...
  6. Environmental factors transmitted by aryl hydrocarbon receptor influence severity of psoriatic skin inflammation [Affymetrix] BioProject

    ID: PRJNA206508

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: show that the aryl hydrocarbon receptor (AhR), a transcription factor that senses environmental stimuli, modulates pathology in psoriasis. AhR-activating ligands reduced inflammation in the lesional skin of psoriasis patients, whereas AhR antagonists upregulated inflammation. Similarly, Ah...
  7. Environmental factors transmitted by aryl hydrocarbon receptor influence severity of psoriatic skin inflammation [RNA-Seq] BioProject

    ID: PRJNA208430

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: show that the aryl hydrocarbon receptor (AhR), a transcription factor that senses environmental stimuli, modulates pathology in psoriasis. AhR-activating ligands reduced inflammation in the lesional skin of psoriasis patients, whereas AhR antagonists upregulated inflammation. Similarly, Ah...
  8. Characterization of transcriptome changes induced in 3T3L1 adipocytes by expression of Adenovirus subtype 5 protein E4-ORF1 BioProject

    ID: PRJNA352729

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: rter to plasma membrane and inactivation of FoxO1 transcription factor. Adenoviral protein E4-ORF1 stimulates cellular glucose metabolism by mimicking growth factor activation of PI3 kinase. We have used E4-ORF1 to dissect PI3 kinase-mediated signaling in adipocytes. E4-ORF1 activ...
  9. PEA15 regulates the DNA damage induced cell cycle checkpoint and oncogene-directed transformation BioProject

    ID: PRJNA170510

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ss of PEA15 accelerates cell cycle progression by activating CDK6 expression via the c-JUN transcription factor. Cells lacking PEA15 exhibit a DNA damage-induced G2/M checkpoint defect due to increased CDC25C activity and consequentially higher CDK1/Cyclin B activity and accordingly have an increased rate of spontaneous mutagenesis. We find that oncogenic RAS inhibits PEA15 expression and ectopic PEA15 expression blocks RAS-mediated transfo...
  10. Genome-wide localization of the RNA polymerase III transcription machinery in human cells BioProject

    ID: PRJNA119545

    Keywords: Epigenomics

    Access Type: download

  11. Gene expression profiling of pancreatic cancer cell line BxPC-3 induced by PAR-2 AP BioProject

    ID: PRJNA192255

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: cancer development. In this study, we used PAR-2 activating peptide to mimic the action of trypsin to trigger PAR-2 signaling pathway and effects of PAR-2 activation on gene expression in human pancreatic cancer cell line BxPC-3 investigated by microarray analysis. Through DAVID bioinformatic resources, we observed that activated PAR-2-mediated genes are summarize...
  12. Co-addiction to IRF4 and SPIB in ABC-DLBCL BioProject

    ID: PRJNA147741

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: RNA interference screens identified the transcription factor IRF4 as essential for the survival of the activated B-cell-like subtype of diffuse large B-...
  13. MYBPH, a novel transcriptional target of NKX2-1/TTF-1, inhibits ROCK1 and actomyosin assembly, and reduces cell motility and tumor metastasis BioProject

    ID: PRJNA136129

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. Genome-wide analysis of the SNAPc complex [Illumina array] ArrayExpress

    ID: E-GEOD-41528

    Description: The small nuclear RNA (snRNA)-activating protein complex (SNAPc) is a basal transcription factor that mediates the transcri...

  15. Genome-wide analysis of the SNAPc complex [ChIP-Seq] ArrayExpress

    ID: E-GEOD-37403

    Description: The small nuclear RNA (snRNA)-activating protein complex (SNAPc) is a basal transcription factor that mediates the transcri...

  16. Genome-wide analysis of ATF4 binding in histidinol-treated cells ArrayExpress

    ID: E-GEOD-69304

    Description: Activating Transcription Factor 4 (ATF4) is a transcription

  17. Gene expression profiles of PNT1a prostate cells expressing FGFR-4 Arg388 or Gly388. BioProject

    ID: PRJNA124407

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: hown that serum contains abundant FGFs capable of activating FGFR-4 so these initial experiments were carried out in serum to mimic physiological conditions. In such conditions the Arg388 expressing PNT1a cells display increased invasiveness and motility compared to Gly388 expressing cells. FGFR-4 Arg388 allele shows increased receptor stability and sustained receptor activation following ligand binding when compared to the Gly388 allele. However, the impact of this sustain...
  18. Transciptome profiling of small intestinal epithelial crypt and villi in germfree versus conventional neonatal piglets BioProject

    ID: PRJNA97945

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: cascade using signal transducer and activator of transcription-1 (STAT1), STAT2 and IFN regulatory factor-7 transcription factors to activate IFN-inducible genes. In addition, excessive inflammatory responses were prevented by activating RNA expression of inhibitory-kappa-B and Toll-interacting protein, along with downregulating the expression of a gene encoding GATA binding protein-1 consistent with the maintenance of intestinal homeostasis. This study supports the concept that the intestinal epithelium has evolved to maintain a physiological state of inflammation with respect to continuous microbial exposure, which serves to maintain tight intestinal barrier but prevent overt inflammatory responses that would compromise barrier function. Keywords: oligonucleotide array Overall design: Four piglets from one isolator were maintained germfree and four piglets in other isolator were conventionalized by fecal slurry. Laser capture microdissection was used to recover epithelial villus and crypt cells from frozen ileal sections. Porcine oligonucleotide set represents 13,297 porcine cDNAs and ESTs. A reference design was used in which each of the experimental samples was cohybridized with the reference sample ...
  19. H3K27ac ChIP-Seq in ALL-SIL BioProject

    ID: PRJNA289457

    Keywords: Epigenomics

    Access Type: download

    dataset.description: The T-cell leukemia homeobox 1 (TLX1, HOX11) transcription factor is critically involved in the multistep pathogenesis of ...
  20. Adipocyte XBP1s regulates systemic insulin sensitivity by modulating adiponectin multimerization BioProject

    ID: PRJNA151747

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: role of the spliced form of X-box-binding protein 1 (XBP1s), a key transcription factor of the endoplasmic reticulum (ER) stress response, in adipose tissue rema...

Displaying 20 of 607 results for "ATF1"