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Displaying 20 of 607 results for "ATF1"
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  1. Genome-wide expression profile analysis of the Candida glabrata Pdr1 regulon ArrayExpress

    ID: E-GEOD-24168

    Description: stance in the pathogenic fungus Candida glabrata. Activating mutations in CgPDR1, a zinc cluster transcription factor, result in constitutive up-regulation of these ABC-transporter genes but to varying degrees. We examined...

  2. Mineralocorticoid receptor ligand-binding domain with compuond 37a PDB

    ID: PDB:4PF3

    Description: Mineralocorticoid receptor

    dataset.keywords: TRANSCRIPTION/TRANSCRIPTION INHIBITOR
  3. Gene expression data from MGHU3 bladder cancer cells (FGFR3-Y375C) treated with TAK1 siRNA and/or PD173074 BioProject

    ID: PRJNA228972

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: The NFκB transcription factor is constitutively active in a number of hematologic and solid tumors, and many signaling pa...
  4. Identification of WUSCHEL direct targets. BioProject

    ID: PRJNA140197

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ipheral zone (PZ). WUSCHEL (WUS) is a homeodomain transcription factor produced in a few cells of the organizing center (OC), located beneath the CZ. It has been shown to specify stem cell fate and also activate CLAVATA3 (CLV3) expression in cells of the CZ. CLV3 is a secreted peptide that activates a membrane bound receptor kinase-CLAVATA1 to restrict WUS
  5. GC-rich Sequence Elements Recruit Polycomb Repressive Complex 2 (PRC2) in ES cells ArrayExpress

    ID: E-GEOD-25197

    Description: othesized that large GC-rich elements depleted of activating transcription factor motifs mediate PRC2 recruitment in mammals. We validated this model in two ways. First, we showed that a constitutively active CpG island is able to recruit PRC2 after excision of a cluster of activating motifs. Second, we showed that two 1 kb sequence intervals from the E. coli genome with GC-contents comparable to a mammalian CpG island are both capable of recruiting PRC2 when integrated into the ES cell genome. Our findings demonstrate a causal role for GC-rich sequences in PRC2 recruitment and implicate a specific subset of CpG islands depleted of activating motifs as instrumental for the initial localization of this key regulator in mammalian genomes. Analysis of YY1 binding in two cell types...

  6. Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation BioProject

    ID: PRJNA247384

    Keywords: Other

    Access Type: download

  7. Crosstalk between androgen and proinflammatory signaling activates a distinct transcription program in prostate cancer cells BioProject

    ID: PRJNA327218

    Keywords: Other

    Access Type: download

  8. Gene expression during early Arabidopsis flower development BioProject

    ID: PRJNA94451

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: e synchronized flower development by specifically activating the AP1-GR fusion protein in ap1 cal inflorescence-like meristems through dexamethasone treatment. Tissue samples were collected immediately after the treatment, as well as at one-day intervals for the following five days. The expression profiles of...
  9. The effect of Crem absence on gene expression in mouse testis. BioProject

    ID: PRJNA153837

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ive element modulator) together with CREB and ATF-1 belong to the CREB family of transcriptional factors, that respond to cyclic AMP signaling and bind to cAMP responsive element (CRE) sites in promo...
  10. Intrinsic transcriptional heterogeneity in B cells controls early class switching to IgE BioProject

    ID: PRJEB14546

    Keywords: Other

    Access Type: download

    dataset.description: B cells. Differential regulation of Iε and Iγ1 transcription in response to interleukin-4 (IL-4), hence class switching to IgE and IgG1, is not fully understood. Here we combine novel mouse reporters and single-cell RNA-seq to reveal the heterogeneity in IL-4 induced I-transcription. Transgenic mice were generated with one allele label...
  11. The effect of Crem absence on gene expression in mouse adrenal glands. BioProject

    ID: PRJNA153835

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ive element modulator) together with CREB and ATF-1 belong to the CREB family of transcriptional factors, that respond to cyclic AMP signaling and bind to cAMP responsive element (CRE) sites in promo...
  12. The effect of Crem absence on gene expression in mouse liver. BioProject

    ID: PRJNA153839

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ive element modulator) together with CREB and ATF-1 belong to the CREB family of transcriptional factors, that respond to cyclic AMP signaling and bind to cAMP responsive element (CRE) sites in promo...
  13. Epigenomic plasticity enables human pancreatic alpha to beta cell reprogramming BioProject

    ID: PRJNA217397

    Keywords: Other

    Access Type: download

    dataset.description: xhibited many more genes bivalently marked by the activating H3K4me3 and repressing H3K27me3 histone modifications. This was particularly true for β cell signature genes involved in transcriptional regulation. Remarkably, thousands of these genes were in a monovalent state in β cells, carrying only the activating or repressing mark. Our epigenomic findings suggested that α to β cell reprogramming could be promoted by manipulating the histone methylation signature of human pancreatic islets. Indeed, we show that treatment of cultured pancreati...
  14. Downstream targets of ID1 transcription factor in Non-Small Cell Lung Carcinoma (NSCLC) OmicsDI

    ID: E-GEOD-38944

    Date Released: 06-02-2014

    Description: ID-1, known as inhibitor of differentiation or a helix loop helix transcription factor which lac...

  15. Acute Genome-Wide Effects of Rosiglitazone on PPARγ Transcriptional Networks in Adipocytes BioProject

    ID: PRJNA213884

    Keywords: Epigenomics

    Access Type: download

    dataset.description: in adipocytes. Treatment with Rosiglitazone for 1 hour leads to acute transcriptional activation as well as repression of a number of genes as determined by genome-wide RNA polymerase II occupancy. Unlike what has been shown for many other nuclear receptors, agonist treatment does not lead to major changes in the occ...
  16. In vitro response of fibroblasts isolated from patients with immunodeficiencies BioProject

    ID: PRJNA113783

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ed distinct patterns or responsiveness to stimuli activating the Toll-like/IL1 Receptor pathway in either an MYD88-dependent (IL1B) or independent (poly(I:C)) fashion, or activating the TNF pathway. The prototypic signatures in cell lines derived from patients were as follows: NEMO-deficient cells were unresponsive to all three stimuli, UNC-93B-deficient cells did not respond to poly(I:C), and STAT1-deficient cells responded only weakly to poly(I:C) after eight hours (not shown). MyD88- and IRAK-4-defi...
  17. Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis BioProject

    ID: PRJNA302814

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ional integrity of Treg cells is maintained under activating environments is unclear. Here we show that autophagy is active in Treg cells and supports their lineage stability and survival fitness. Treg cell–specific deletion of Atg7 or Atg5, both essential genes in autophagy, leads to loss of T...
  18. Transcription profiling of human peripheral blood mononuclear cells WITH a germline NRAS mutation vs controls reveals NRAScauses ... OmicsDI

    ID: E-GEOD-7345

    Date Released: 06-10-2011

    Description: ling networks, and is the most frequent target of activating mutations in cancer. Activating germline mutations of KRAS and HRAS cause severe developmental abnormalities leading to Noonan, cardio-facial-cutaneous and Costello syndrome, but activating germline mutations of NRAS have no...

  19. Transcription profiling of mouse adult primary neural stem cells when stimulated with the proliferative agent PACAP (pituitary aden... ArrayExpress

    ID: E-MEXP-322

    Description: ferative agent PACAP (pituitary adenylate cyclase-activating polypeptide). In addition the data was compared to results obtained from a proliferation control (stimulation with a transmembrane receptor agonist) and a differentiation control (primary neural stem cells induced to differentiate by ...

  20. Alterations in Gene Expression in Human Mesothelial Cells Correlate with Mineral Pathogenicity BioProject

    ID: PRJNA112389

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Human mesothelial cells (LP9/TERT-1) were exposed to low and high (15 and 75 μm2/cm2 dish) equal surface area concentrations of crocidolite asbestos, nonfibrous tal...

Displaying 20 of 607 results for "ATF1"