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Displaying 60 of 60 results for "ATAD2"
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  1. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with thymine PDB

    ID: PDB:4QSU

    Description: ATPase family AAA domain-containing protein

  2. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with N-Methyl-2-pyrrolidone (NMP) PDB

    ID: PDB:4QSS

    Description: ATPase family AAA domain-containing protein

  3. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 3'-deoxy thymidine PDB

    ID: PDB:4QSX

    Description: ATPase family AAA domain-containing protein

  4. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 5-methyl uridine PDB

    ID: PDB:4QSW

    Description: ATPase family AAA domain-containing protein

  5. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) with bound DMSO PDB

    ID: PDB:4QSQ

    Description: ATPase family AAA domain-containing protein

  6. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with 1-methylquinolin 2-one PDB

    ID: PDB:4QST

    Description: ATPase family AAA domain-containing protein

  7. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) with bound MPD PDB

    ID: PDB:4QSR

    Description: ATPase family AAA domain-containing protein

  8. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with acetyl-lysine PDB

    ID: PDB:4QSP

    Description: ATPase family AAA domain-containing protein

  9. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) in complex with thymidine PDB

    ID: PDB:4QSV

    Description: ATPase family AAA domain-containing protein

  10. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)12 PDB

    ID: PDB:4QUT

    Description: ATPase family AAA domain-containing protein

  11. Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)5 PDB

    ID: PDB:4QUU

    Description: ATPase family AAA domain-containing protein

  12. Crystal structure of the bromodomain of the human ATAD2 PDB

    ID: PDB:3DAI

    Description: ATPase family AAA domain-containing protein

  13. ATAD2_PONAB UniProt:Swiss-Prot

    ID: Q5RDX4

    Description: ATPase family AAA domain-containing protein

  14. Fragment-Based Screening of the Bromodomain of ATAD2 PDB

    ID: PDB:4TZ2

    Description: ATPase family AAA domain-containing protein

  15. Crystal structure of human ATAD2 bromodomain in complex with 8-(((3R,4R,5S)-3-((4,4-difluorocyclohexyl)methoxy)-5-methoxypiperidin-4-yl)amino)-3-methyl-5-(5-m... PDB

    ID: PDB:5LJ0

    Description: ATPase family AAA domain-containing protein

  16. Fragment-Based Screening of the Bromodomain of ATAD2 PDB

    ID: PDB:4TYL

    Description: ATPase family AAA domain-containing protein

  17. Structure of human ATAD2 bromodomain bound to fragment inhibitor PDB

    ID: PDB:4TZ8

    Description: ATPase family AAA domain-containing protein

  18. Crystal structure of human ATAD2 bromodomain in complex with 8-(3R,4R) -3-(cyclohexylmethoxy)piperidin-4-yl-amino-3-methyl-1,2-dihydro-1,7- naphthyridin- PDB

    ID: PDB:5A81

    Description: ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN

  19. Crystal structure of human ATAD2 bromodomain in complex with 8-2-(dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one PDB

    ID: PDB:5A5P

    Description: ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN

  20. Crystal structure of human ATAD2 bromodomain in complex with 3-methyl- 8-piperidin-4-ylamino-1,2-dihydro-1,7-naphthyridin-2-one hydrochloride PDB

    ID: PDB:5A5Q

    Description: ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN

  21. Crystal structure of human ATAD2 bromodomain in complex with 5-5- methoxypyridin-3-yl-3-methyl-8-piperidin-4-ylamino-1,2-dihydro-1,7- naphthyridin- PDB

    ID: PDB:5A5R

    Description: ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN

  22. Crystal structure of human ATAD2 bromodomain in complex with 4-(3R,4R) -4-(3-methyl-2-oxo-1,2-dihydro-1,7-naphthyridin-8-yl)aminopiperidin-... PDB

    ID: PDB:5A82

    Description: ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN

  23. Crystal structure of human ATAD2 bromodomain in complex with 4-((3R, 4R)-4-3-methyl-5-(5-methylpyridin-3-yl)-2-oxo-1,2-dihydroquinolin-8- y... PDB

    ID: PDB:5A83

    Description: ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN

  24. Crystal structure of human ATAD2 bromodomain in complex with (2S)-2,6- diacetamido-N-methylhexanamide PDB

    ID: PDB:5A5N

    Description: ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN

  25. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells [Atad2_ES_Chipseq1_BI] BioProject

    ID: PRJNA288303

    Keywords: Epigenomics

    Access Type: download

  26. Crystal structure of human ATAD2 bromodomain in complex with 3-methyl- 1,2-dihydroquinolin-2-one PDB

    ID: PDB:5A5O

    Description: ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN

  27. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells [Microarray transcriptomic analysis] BioProject

    ID: PRJNA287043

    Keywords: Transcriptome or Gene expression

    Access Type: download

  28. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells [Atad2_ES_ChIPseq2_MG2] BioProject

    ID: PRJNA288302

    Keywords: Epigenomics

    Access Type: download

  29. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells [Atad2_ES_RNAseq_BI] BioProject

    ID: PRJNA288301

    Keywords: Transcriptome or Gene expression

    Access Type: download

  30. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells [Microarray transcriptomic analysis] OmicsDI

    ID: E-GEOD-69899

    Date Released: 04-05-2016

    Description: Although the conserved AAA ATPase – bromodomain factor, ATAD2, has been described as a transcriptional co-activato...

  31. GSK8814: a chemical probe fort he ATAD2 bromodomain BioProject

    ID: PRJNA314233

    Keywords: Transcriptome or Gene expression

    Access Type: download

  32. ATAD3_CAEEL UniProt:Swiss-Prot

    ID: Q20748

    Description: ATPase family AAA domain-containing protein 3 Mitochond...

  33. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells [Microarray transcriptomic analysis] ArrayExpress

    ID: E-GEOD-69899

    Description: Although the conserved AAA ATPase – bromodomain factor, ATAD2, has been described as a transcriptional co-activato...

  34. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells BioProject

    ID: PRJNA288300

    Access Type: download

  35. Crystal structure of the bromodomain of human ATAD2 in complex with Compound A14 PDB

    ID: PDB:5F3A

    Description: EPH receptor A3 (E.C.2.7.10.1)

  36. Crystal structure of the bromodomain of human ATAD2 in complex with Compound 49 PDB

    ID: PDB:5EPB

    Description: EPH receptor A3 (E.C.2.7.10.1)

  37. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells ArrayExpress

    ID: E-GEOD-70315

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  38. RNA-seq analysis generated a comprehensive landscape of transcriptomes and revealed complex patterns of transcripts in Chinese HBV-related hepatocellu... ArrayExpress

    ID: E-GEOD-25599

    Description: a novel highly up-regulated exon-exon junction in ATAD2 (ATPase family, AAA domain containing 2) gene in HCC tissues. Overall, to our best knowledge, our study represents the most comprehensive characterization of the HBV-related HCC transcriptome including exon level expression changes and novel splicing variants, which illustrated the power of RNA-seq and provided important clues for understanding the molecular mechanisms of HCC pathogenesis at system-wide levels. A comprehensive analysis of transcriptome for 10 match-paired HBV-related Chinese HCC and non-cancerous adjacent tissues. Processed data files: Exon-level results, gene-level results, differentially expressed exons, and differently expressed genes (DEGs)....

  39. GSK8814: a chemical probe fort he ATAD2 bromodomain ArrayExpress

    ID: E-GEOD-78868

    Description: Differential gene expression analysis of LNCaP cells treated with GSK8814 and GSK8815 Total RNA obtained from cells treated with GSK8814 and GSK8815 f...

  40. Functional cooperation between AAA-ATPase domain and a bromodomain. BioProject

    ID: PRJNA113667

    Keywords: Transcriptome or Gene expression

    Access Type: download

  41. Crystal structure of the bromodomain of human ATAD2 in complex with Compound A12 PDB

    ID: PDB:5F36

    Description: EPH receptor A3 (E.C.2.7.10.1)

  42. Crystal structure of ATAD2A bromodomain complexed with methyl 3-amino-5-(3,5-dimethyl-1,2-oxazol-4-yl)benzoate PDB

    ID: PDB:4TTE

    Description: ATPase familly AAA domain-containing protein 2 (E.C.3.6...

  43. Crystal structure of ATAD2A bromodomain complexed with H3(1-21)K14Ac peptide PDB

    ID: PDB:4TT4

    Description: ATPase familly AAA domain-containing protein 2 (E.C.3.6...

  44. RNA-seq analysis generated a comprehensive landscape of transcriptomes and revealed complex patterns of transcripts in Chinese HBV-related hepatocellu... OmicsDI

    ID: E-GEOD-25599

    Date Released: 05-03-2014

    Description: a novel highly up-regulated exon-exon junction in ATAD2 (ATPase family, AAA domain containing 2) gene in HCC tissues. Overall, to our best knowledge, our study represents the most comprehensive characterization of the HBV-related HCC transcriptome including exon level expression changes and novel splicing variants, which illustrated the power of RNA-seq and provided important clues for understanding the molecular mechanisms of HCC pathogenesis at system-wide levels. A comprehensive analysis of transcriptome for 10 match-paired HBV-related Chinese HCC and non-cancerous adjacent tissues. Processed data files: Exon-level results, gene-level results, differentially expressed exons, and differently expressed genes (DEGs)....

  45. Crystal structure of ATAD2A bromodomain complexed with H4(1-20)K5Ac peptide PDB

    ID: PDB:4TT2

    Description: ATPase familly AAA domain-containing protein 2 (E.C.3.6...

  46. Crystal Structure of the Bromodomain of Human AAA domain containing 2B (ATAD2B) PDB

    ID: PDB:3LXJ

    Description: ATPase family AAA domain-containing protein 2B

  47. Crystal structure of ATAD2A bromodomain double mutant N1063A-Y1064A in apo form PDB

    ID: PDB:4TT6

    Description: ATPase familly AAA domain-containing protein 2 (E.C.3.6...

  48. Crystal structure of apo ATAD2A bromodomain with N1064 alternate conformation PDB

    ID: PDB:4TU6

    Description: ATPase familly AAA domain-containing protein 2 (E.C.3.6...

  49. Crystal structure of ATAD2A bromodomain complexed with 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-[(phenylsulfonyl)amino]benzoicacid PDB

    ID: PDB:4TU4

    Description: ATPase familly AAA domain-containing protein 2 (E.C.3.6...

  50. RNA-seq analysis generated a comprehensive landscape of transcriptomes and revealed complex patterns of transcripts in Chinese HBV-related hepatocellu... BioProject

    ID: PRJNA134241

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: a novel highly up-regulated exon-exon junction in ATAD2 (ATPase family, AAA domain containing 2) gene in HCC tissues. Overall, to our best knowledge, our study represents the most comprehensive characterization of the HBV-related HCC transcriptome including exon level expression changes and novel splicing variants, which illustrated the power of RNA-seq and provided important clues for understanding the molecular mechanisms of HCC pathogenesis at system-wide levels. Overall design: A comprehensive analysis of transcriptome for 10 match-paired HBV-related Chinese HCC and non-cancerous adjacent tissues. Processed data files: Exon-level results, gene-level results, differentially expressed exons, and differently expressed genes (DEGs)....
  51. GSK8814: a chemical probe fort he ATAD2 bromodomain OmicsDI

    ID: E-GEOD-78868

    Date Released: 09-01-2016

    Description: Differential gene expression analysis of LNCaP cells treated with GSK8814 and GSK8815 Total RNA obtained from cells treated with GSK8814 and GSK8815 f...

  52. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells OmicsDI

    ID: E-GEOD-70315

    Date Released: 03-25-2016

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  53. Characterization of CT26 colon carcinoma : Extensive characterization of the CT26 colorectal carcinoma genome, transcriptome and immunome BioProject

    ID: PRJEB5321

    Keywords: Other

    Access Type: download

    dataset.description: n cancer-testis antigens are expressed, including Atad2, Cep55, and Pbk. The highest expressed gene is a mutated form of the mouse tumor antigen gp70. Of the 1,688 non-synonymous point variations, 154 are both in expressed genes and in peptides predicted to bind MHC and thus potential targets for immunotherapy development. Based on its molecular signature, we predicted that CT26 is refractory to anti-EGFR mAbs and sensitive to MEK and MET inhibitors, as have been previously reported. CONCLUSIONS: CT26 cells share molecular features with aggressive, undifferentiated, refractory human colorectal carcinoma cells. As CT26 is one of the most extensively used syngeneic mouse tumor models, our data provide a map for the rationale design of mode-of-action studies for pre-clinical evaluation of targeted- and immunotherapies....
  54. Breast Brain Metastasis, Non-Neoplastic Brain, and Non-Neoplastic Breast Gene Expression ArrayExpress

    ID: E-GEOD-52604

    Description: uently amplified and overexpressed genes included ATAD2, BRAF, DERL1, DNMTRB and NEK2A. The ATM, CRYAB and HSPB2 genes were commonly deleted and underexpressed. Knowledge mining revealed enrichment in cell cycle and G2/M transition pathways, which contained AURKA, AURKB and FOXM1. Using the PAM50 breast cancer intrinsic classifier, Luminal B, Her2+/ER negative, and basal-like tumors were identified as the most commonly represented breast cancer subtypes in our CNS metastasis cohort. While overall methylation levels were increased in breast cancer CNS metastasis, basal-like CNS metastases were associated with significantly lower levels of methylation. Integrating DNA methylation data with gene expression revealed defects in cell migration and ad...

  55. -methyl-5-(5-methylpyridin-3-yl)-1,7-naphthyridin-2(1H)-one... PDB

    ID: PDB:5LJ1

    Description: Bromodomain-containing protein 4

  56. NN-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 5-5-methoxypyridin-3-yl-3- methyl-8-piperidin-4-ylamino-1,2-dihydro-1,7-naphthyridin-2-one PDB

    ID: PDB:5A5S

    Description: BROMODOMAIN-CONTAINING PROTEIN 4

  57. N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 8-(3R,4R)-3-(cyclohexylmethoxy)piperidin-4-ylamino-3-methyl-1,2-dihydro-1,7- naphthyridin-2-one PDB

    ID: PDB:5A85

    Description: BROMODOMAIN-CONTAINING PROTEIN 4

  58. y)piperidin-4-yl)amino)-3-methyl-1,7-naphthyridin-2(1H)-one... PDB

    ID: PDB:5LJ2

    Description: Bromodomain-containing protein 4

  59. Breast Brain Metastasis, Non-Neoplastic Brain, and Non-Neoplastic Breast Gene Expression BioProject

    ID: PRJNA229461

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: uently amplified and overexpressed genes included ATAD2, BRAF, DERL1, DNMTRB and NEK2A. The ATM, CRYAB and HSPB2 genes were commonly deleted and underexpressed. Knowledge mining revealed enrichment in cell cycle and G2/M transition pathways, which contained AURKA, AURKB and FOXM1. Using the PAM50 breast cancer intrinsic classifier, Luminal B, Her2+/ER negative, and basal-like tumors were identified as the most commonly represented breast cancer subtypes in our CNS metastasis cohort. While overall methylation levels were increased in breast cancer CNS metastasis, basal-like CNS metastases were associated with significantly lower levels of methylation. Integrating DNA methylation data with gene expression revealed defects in cell migration and ad...
  60. Breast Brain Metastasis, Non-Neoplastic Brain, and Non-Neoplastic Breast Gene Expression OmicsDI

    ID: E-GEOD-52604

    Date Released: 06-03-2014

    Description: uently amplified and overexpressed genes included ATAD2, BRAF, DERL1, DNMTRB and NEK2A. The ATM, CRYAB and HSPB2 genes were commonly deleted and underexpressed. Knowledge mining revealed enrichment in cell cycle and G2/M transition pathways, which contained AURKA, AURKB and FOXM1. Using the PAM50 breast cancer intrinsic classifier, Luminal B, Her2+/ER negative, and basal-like tumors were identified as the most commonly represented breast cancer subtypes in our CNS metastasis cohort. While overall methylation levels were increased in breast cancer CNS metastasis, basal-like CNS metastases were associated with significantly lower levels of methylation. Integrating DNA methylation data with gene expression revealed defects in cell migration and ad...


Displaying 60 of 60 results for "ATAD2"