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Displaying 100 of 179 results for "AIG1"
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  1. AIG1_ARATH UniProt:Swiss-Prot

    ID: P54120

    Description: Protein AIG1 AIG1-type G GTP GTP GTP

  2. GIMA8_HUMAN UniProt:Swiss-Prot

    ID: Q8ND71

    Description: GTPase IMAP family member 8 AIG1-type G 1 AIG1-type G 2 AIG1-type G 3 GTP GTP Poly-Leu Poly-Val GTP GT...

  3. the Arabidopsis Abscisic Acid Insensitive Growth 1 (AIG1) Transcription Factor cDNA... ArrayExpress

    ID: E-GEOD-70100

    Description: NA encoding the Abscisic Acid Insensitive Growth (AIG1) gene under the control of an estrogen inducible promoter were treated with estrogen for 0, 60 and 120 minutes at which point seedlings were flash frozen and mRNA was extracted. Wild-type and ESTAIG1 Col samples w...

  4. BH032_ARATH UniProt:Swiss-Prot

    ID: Q9LS08

    Description: Transcription factor AIG1 bHLH

  5. the Arabidopsis Abscisic Acid Insensitive Growth 1 (AIG1) Transcription Factor cDNA... OmicsDI

    ID: E-GEOD-70100

    Date Released: 06-26-2016

    Description: NA encoding the Abscisic Acid Insensitive Growth (AIG1) gene under the control of an estrogen inducible promoter were treated with estrogen for 0, 60 and 120 minutes at which point seedlings were flash frozen and mRNA was extracted. Wild-type and ESTAIG1 Col samples w...

  6. Transcriptional profiling by array of Entamoeba histolytica Mutant Derived from Virulent Strain ArrayExpress

    ID: E-MTAB-3525

    Description: ulent UG10 mutant derived from E. histolytica HM-1:IMSS. Comparing the transcriptome of both strains, no differences in gene expression of the classical virulence factors were observed. RAB family GTPase and AIG1 family members showed higher transcriptional levels in the virulent strain than in the non-virulent mutant. Our study suggests a number of novel gene products in E. histolytica with a role yet to determine in cell physiology and involvement in the pathogenesis process....

  7. P2A03_ARATH UniProt:Swiss-Prot

    ID: O81025

    Description: Putative protein PHLOEM PROTEIN 2-LIKE A3 AIG1-type G

  8. GIMA6_RAT UniProt:Swiss-Prot

    ID: Q5FVN6

    Description: GTPase IMAP family member 6 AIG1-type G GTP GTP GTP GTP

  9. GIMD1_HUMAN UniProt:Swiss-Prot

    ID: P0DJR0

    Description: GTPase IMAP family member GIMD1 AIG1-type G GTP GTP GTP

  10. TC120_ARATH UniProt:Swiss-Prot

    ID: Q9LUS2

    Description: slocase of chloroplast 120, chloroplastic Helical AIG1-type G GTP GTP GTP Homodimerization Homodimerization Magnesium GTP; via amide nitrogen N-acetylglycine Phosphoserine Phosphoserine Phospho...

  11. GIMD1_MOUSE UniProt:Swiss-Prot

    ID: E9PW74

    Description: GTPase IMAP family member GIMD1 AIG1-type G GTP GTP GTP

  12. GIMA7_HUMAN UniProt:Swiss-Prot

    ID: Q8NHV1

    Description: GTPase IMAP family member 7 AIG1-type G GTP GTP GTP GTP Important for catalytic activity In dbSNP:rs3735080. Abolishes GTPase activity. No effect on GTP bindin...

  13. GIMA4_HUMAN UniProt:Swiss-Prot

    ID: Q9NUV9

    Description: GTPase IMAP family member 4 AIG1-type G GTP GTP GTP GTP In dbSNP:rs2293172.

  14. GIMA6_BOVIN UniProt:Swiss-Prot

    ID: A5PKB7

    Description: GTPase IMAP family member 6 AIG1-type G GTP GTP GTP GTP

  15. GIMA4_MOUSE UniProt:Swiss-Prot

    ID: Q99JY3

    Description: GTPase IMAP family member 4 AIG1-type G GTP GTP GTP GTP

  16. GIMA4_RAT UniProt:Swiss-Prot

    ID: Q8K3K9

    Description: GTPase IMAP family member 4 AIG1-type G GTP GTP GTP GTP

  17. GIMA1_MOUSE UniProt:Swiss-Prot

    ID: P70224

    Description: GTPase IMAP family member 1 Cytoplasmic Helical; Anchor for type IV membrane protein Lumenal AIG1-type G GTP GTP GTP GTP...

  18. GIMD1_RAT UniProt:Swiss-Prot

    ID: B0BMZ3

    Description: GTPase IMAP family member GIMD1 AIG1-type G GTP GTP GTP

  19. Gallup News Service Poll: AIG Bonuses Dataverse

    Description: is survey covers the following issues and topics: AIG bonus payments to executives (2); Barack Obama job performance (1); economic conditions (2); direction of coun...

    Person: Gallup Organization

    Release Date: 10-19-2010

  20. USA Today/Gallup Poll # 2009-TR0321: AIG Bonuses Dataverse

    Description: the following issues and topics: Groups handling AIG bailout (4); blame for bonuses (1); returning bonus money (1); recovering bonus money (1...

    Person: USA Today

    Release Date: 10-19-2010

  21. Androgen arrays for Resveratrol-Induced Gene Expression Profiles in Human Prostate Cancer BioProject

    ID: PRJNA104663

    Keywords: Transcriptome or Gene expression

    Access Type: download

  22. Crystal structure of the human androgen receptor T877A mutant ligand-binding domain with cyproterone acetate PDB

    ID: PDB:2OZ7

    Description: Androgen receptor

  23. GIMD1_BOVIN UniProt:Swiss-Prot

    ID: G3MZQ6

    Description: GTPase IMAP family member GIMD1 AIG1-type G GTP GTP GTP

  24. Transcription profiling of mouse bFGF-treated JB6 cells and fully tumorigenic JB6 cells from the RT101 cell line - reversible and irreversible anchor... ArrayExpress

    ID: E-GEOD-13979

    Description: d the regulation of anchorage-independent growth (AIG) by basic fibroblast growth factor (bFGF) and 12-O-tetradecanoyl phorbol-13-acetate (TPA) in JB6 mouse epidermal cells in the context of wound rep...

  25. CBS News Poll: Financial Crisis/AIG Dataverse

    Description: gressional job performance (2); Timothy Geithner (1); federal aid to financial institutions (2); company bonuses (15)....

    Person: CBS News

    Release Date: 10-19-2010

  26. Transcriptional profiling by array of Entamoeba histolytica Mutant Derived from Virulent Strain OmicsDI

    ID: E-MTAB-3525

    Date Released: 04-23-2015

    Description: ulent UG10 mutant derived from E. histolytica HM-1:IMSS. Comparing the transcriptome of both strains, no differences in gene expression of the classical virulence factors were observed. RAB family GTPase and AIG1 family members showed higher transcriptional levels in the virulent strain than in the non-virulent mutant. Our study suggests a number of novel gene products in E. histolytica with a role yet to determine in cell physiology and involvement in the pathogenesis process....

  27. TALEN-Engineered AR Gene Rearrangements Reveal Endocrine Uncoupling of Androgen Receptor in Prostate Cancer BioProject

    ID: PRJNA213269

    Keywords: Transcriptome or Gene expression

    Access Type: download

  28. Crosstalk between androgen and proinflammatory signaling activates a distinct transcription program in prostate cancer cells BioProject

    ID: PRJNA327218

    Keywords: Other

    Access Type: download

  29. Androgen-Induced Rhox Homeobox Genes Modulate the Expression of AR-Regulated Genes BioProject

    ID: PRJNA121257

    Keywords: Transcriptome or Gene expression

    Access Type: download

  30. Transcriptional profiles induced by either androgen depletion or androgen receptor knockdown ArrayExpress

    ID: E-GEOD-7585

    Description: Although the vital role of the androgen receptor (AR) has been well demonstrated in primary prostate cancers, its role in the androgen-insensit...

  31. ivation of the Arabidopsis ABA INSENSITIVE GROWTH 1 (ABIG1) Transcription Factor cDNA... BioProject

    ID: PRJNA287644

    Keywords: Transcriptome or Gene expression

    Access Type: download

  32. Transcription profiling of human prostate cancer cell lines after androgen depletion and AR knock-down ArrayExpress

    ID: E-SMDB-4028

    Description: Although the vital role of the androgen receptor (AR) has been well demonstrated in primary prostate cancers, its role in the androgen-insensit...

  33. Suppression of androgen receptor mediated gene expression by a sequence-specific DNA binding polyamide BioProject

    ID: PRJNA99843

    Keywords: Transcriptome or Gene expression

    Access Type: download

  34. Genome-wide expression profiling of Hic-5 knockdown in PshTert-AR human myofibroblasts BioProject

    ID: PRJNA205085

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ect of the co-regulator Hic-5 (TGFB1I1) on global androgen receptor transcriptional activity in PShTert-AR prostate fibroblast cells with view to further elucidating the broader biological role of Hic...
  35. Transcriptional programs activated by exposure of human prostate cancer cells to androgen ArrayExpress

    ID: E-GEOD-3451

    Description: prostate cancer cell line LNCaP with a synthetic androgen. We observed statistically significant changes in levels of transcripts of more than 500 genes. Many of these genes were previously reported androgen targets, but most were not previously known to be regulated by androgens. The androgen-induced expression programs in 3 additional androgen

  36. Transcription profiling by array of human LNCaP prostate cancer cells after growth with dihydrotestosterone and treatment with polyamide OmicsDI

    ID: E-GEOD-7708

    Date Released: 05-02-2014

    Description: Androgen Receptor (AR) is essential for the growth and progression of prostate cancer in both hormone-sensitive and hormone-refract...

  37. LNCaP LSD1 knockdown and SP-2509 treatment ChIP-seq data BioProject

    ID: PRJNA311373

    Keywords: Epigenomics

    Access Type: download

    dataset.description: tive histone H3 marks (di-methyl lysine 4 [2MK4]).1 In prostate cancer, specifically, LSD1 also co-localizes with the AR and demethylates repressive 2MK9 histone marks from androgen-responsive AR target genes, facilitating androgen-mediated induction of AR-regulated gene expression and androgen-induced proliferation in <...
  38. Therapy-Induced Developmental Reprogramming of Prostate Cancer Cells and Acquired Resistance [Dataset 1] BioProject

    ID: PRJNA278089

    Keywords: Transcriptome or Gene expression

    Access Type: download

  39. Induced Pluripotency of Human Prostatic Epithelial Cells BioProject

    ID: PRJNA194105

    Keywords: Epigenomics

    Access Type: download

  40. Kinase activity profiling shows osteoblast-induced EGFR/ERBB2 signaling in human androgen-sensitive prostate carcinoma cells ArrayExpress

    ID: E-TABM-626

    Description: Osteoblast-induced EGFR/ERBB2 signaling in androgen-sensitive prostate carcinoma cells characterized by multiplex kinase ac...

  41. Androgen arrays for Resveratrol-Induced Gene Expression Profiles in Human Prostate Cancer ArrayExpress

    ID: E-GEOD-4300

    Description: Arrays for Expression levels of androgen-responsive genes in LNCaP cells exposed to dihydrotestosterone, R1881. Gene-expression changes in LNCaP treated with

  42. Additional file 1: Table S1. of Cyproterone acetate enhances TRAIL-induced androgen-independent prostate canc... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3711697_D1

    Release Date: 03-10-2017

    Description: Primer pairs for RT-PCR or construction of plasmids. (XLSX 11 kb)

  43. LNCaP and C42B LSD1 knockdown microarray gene expression data and C42B androgen (DHT) stimulation microarray gene expression data BioProject

    ID: PRJNA261710

    Keywords: Transcriptome or Gene expression

    Access Type: download

  44. LNCaP and C42B LSD1 knockdown microarray gene expression data and C42B androgen (DHT) stimulation microarray gene expression data OmicsDI

    ID: E-GEOD-61630

    Date Released: 06-30-2016

    Description: tive histone H3 marks (di-methyl lysine 4 [2MK4]).1 In prostate cancer, specifically, LSD1 also co-localizes with the AR and demethylates repressive 2MK9 histone marks from androgen-responsive AR target genes, facilitating androgen-mediated induction of AR-regulated gene expression and androgen-induced proliferation in <...

  45. USA Today/Gallup Poll # 2008-TR0917: Wall Street Crisis II Dataverse

    Description: topics: Candidate to handle Wall Street problems (1); Wall Street effecting vote (1); federal government regulating Wall Street (1); federal bailout of American International Group (

    Person: USA Today

    Release Date: 10-19-2010

  46. LNCaP LSD1 knockdown and SP-2509 treatment ChIP-seq data OmicsDI

    ID: E-GEOD-77762

    Date Released: 07-02-2016

    Description: tive histone H3 marks (di-methyl lysine 4 [2MK4]).1 In prostate cancer, specifically, LSD1 also co-localizes with the AR and demethylates repressive 2MK9 histone marks from androgen-responsive AR target genes, facilitating androgen-mediated induction of AR-regulated gene expression and androgen-induced proliferation in <...

  47. Long-term androgen withdrawal and treatment (R1881) of LNCaP-FGC prostate cancer cells ArrayExpress

    ID: E-GEOD-51460

    Description: medium for 5 days before treatment with synthetic androgen (R1881, 10nM) for 16h. Transcriptomics analysis was performed to compare gene expression changes induced by androgen withdrawal or...

  48. Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions ArrayExpress

    ID: E-GEOD-40050

    Description: The androgen receptor (AR) is a ligand-inducible transcription factor that mediates androgen action in target tissue...

  49. Androgen arrays for Resveratrol-Induced Gene Expression Profiles in Human Prostate Cancer OmicsDI

    ID: E-GEOD-4300

    Date Released: 10-18-2011

    Description: Arrays for Expression levels of androgen-responsive genes in LNCaP cells exposed to dihydrotestosterone, R1881. Gene-expression changes in LNCaP treated with

  50. Leptin dependent control of testosterone regulated hepatic lipid metabolism BioProject

    ID: PRJNA130321

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Population based studies have established that androgen deficiency in males correlates with type 2 diabetes, visceral adiposity, and metabolic syndrome. Androgen
  51. Leptin dependent control of testosterone regulated hepatic lipid metabolism OmicsDI

    ID: E-GEOD-23941

    Date Released: 05-01-2014

    Description: Population based studies have established that androgen deficiency in males correlates with type 2 diabetes, visceral adiposity, and metabolic syndrome. Androgen

  52. Tumor-Specific Retrogene NANOGP8 Reprograms Prostate Cancer Cells to Castration Resistance by Engaging the FOXA1/AR Signaling Axis and MYC [RNA-seq] BioProject

    ID: PRJNA301565

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ed oncogenesis and prostate cancer progression to androgen independence. ChIP-Seq analysis of LNCaP prostate cancer cells overexpressing doxycycline-inducible NANOG (either NANOG1 or NANOGP8 vs pLVX control) reveal that NANOG coordinately occupies regions of chromatin regulated by AR signaling steroid-receptor complex proteins AR, FOXA1 and NKX3.1. Taken together with the NANOG-induced changes in the prostate cancer transcriptome (RNA-Seq), NANOG appears to reprogram prostate cancer cells to castration resistance by converging on steroid-...
  53. RUNX2 selectively attenuates or augments androgen-driven transcription in prostate cancer BioProject

    ID: PRJNA229499

    Keywords: Transcriptome or Gene expression

    Access Type: download

  54. A computational systems approach for identification of synergistic specification genes facilitates lineage conversion to prostate tissue BioProject

    ID: PRJNA325519

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: three such master regulators (FOXA1, NKX3.1, and androgen receptor, AR) in a primed conversion strategy to generate prostate tissue from mouse fibroblasts, involving expression of pluripotency factors, tissue recombination with embryonic urogenital mesenchyme, and renal grafting. Overall design: RNA-sequencing profiles of prostate tissues and fibroblasts were generated and compared to RNA-sequen...
  55. Resveratrol-induced gene expression profiles in human prostate cancer cells ArrayExpress

    ID: E-GEOD-4399

    Description: the following subset Series: GSE4299: Resveratrol-Induced Gene Expression Profiles in Human Prostate Cancer Cells GSE4300: Androgen arrays for Resveratrol-Induced Gene Express...

  56. RUNX2 selectively attenuates or augments androgen-driven transcription in prostate cancer OmicsDI

    ID: E-GEOD-52627

    Date Released: 06-03-2014

    Description: tate carcinogenesis is associated with changes in androgen signaling from driving cellular differentiation to promoting oncogenic behaviors. RUNX2 binds the androgen...

  57. Therapy-Induced Developmental Reprogramming of Prostate Cancer Cells and Acquired Resistance [Dataset 2] ArrayExpress

    ID: E-GEOD-66851

    Description: Treatment-induced neuroendocrine transdifferentiation (NEtD) complicates therapies for metastatic prostate cancer (PCa). We propose that NEtD...

  58. Therapy-Induced Developmental Reprogramming of Prostate Cancer Cells and Acquired Resistance [Dataset 1] ArrayExpress

    ID: E-GEOD-66850

    Description: Treatment-induced neuroendocrine transdifferentiation (NEtD) complicates therapies for metastatic prostate cancer (PCa). We propose that NEtD...

  59. Effect of mutating androgen receptor phosphorylation site Tyr-267 ArrayExpress

    ID: E-GEOD-69712

    Description: Reactivation of androgen receptor (AR) may drive recurrent prostate cancer in castrate patients. Ack1 tyrosine kinase is overexpressed in prostate...

  60. Transcription profiling by array of human LNCaP and abl cells after treatment with dihydrotestosterone or androgen receptor siRNA ArrayExpress

    ID: E-GEOD-11428

    Description: Androgen receptor (AR) is a ligand-dependent transcription factor that plays a key role in the onset and progression of prostate ca...

  61. LNCaP LSD1 knockdown and SP-2509 treatment ChIP-seq data ArrayExpress

    ID: E-GEOD-77762

    Description: tive histone H3 marks (di-methyl lysine 4 [2MK4]).1 In prostate cancer, specifically, LSD1 also co-localizes with the AR and demethylates repressive 2MK9 histone marks from androgen-responsive AR target genes, facilitating androgen-mediated induction of AR-regulated gene expression and androgen-induced proliferation in <...

  62. Androgen-induced lncRNA SOCS2-AS1 Promotes Cell Growth and Inhibits Apoptosis in Prostate Cancer Cells ArrayExpress

    ID: E-GEOD-82225

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  63. MCF-7 and ZR-75-1 cell lines hypoxia BioProject

    ID: PRJNA154297

    Keywords: Transcriptome or Gene expression

    Access Type: download

  64. "Drug-seq": An Approach to Identify the Genomic Targets of Chemicals Identified by Functional Phenotypic Screens [GRO-seq] BioProject

    ID: PRJNA241279

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ing for inhibitors of ligand and genotoxic stress-induced translocations in prostate cancer cells. Based on synthesis of a derivatized form of SD70 that permits its application for a ChIP-seq-like approach, referred to as Drug-seq, we were next able to efficiently map the genome-wide binding locations of this small molecule, revealing that it larg...
  65. Therapy-Induced Developmental Reprogramming of Prostate Cancer Cells and Acquired Resistance [Dataset 1] OmicsDI

    ID: E-GEOD-66850

    Date Released: 03-19-2016

    Description: Treatment-induced neuroendocrine transdifferentiation (NEtD) complicates therapies for metastatic prostate cancer (PCa). We propose that NEtD...

  66. RUNX2 selectively attenuates or augments androgen-driven transcription in prostate cancer ArrayExpress

    ID: E-GEOD-52627

    Description: tate carcinogenesis is associated with changes in androgen signaling from driving cellular differentiation to promoting oncogenic behaviors. RUNX2 binds the androgen...

  67. LNCaP and C42B LSD1 knockdown microarray gene expression data and C42B androgen (DHT) stimulation microarray gene expression data ArrayExpress

    ID: E-GEOD-61630

    Description: tive histone H3 marks (di-methyl lysine 4 [2MK4]).1 In prostate cancer, specifically, LSD1 also co-localizes with the AR and demethylates repressive 2MK9 histone marks from androgen-responsive AR target genes, facilitating androgen-mediated induction of AR-regulated gene expression and androgen-induced proliferation in <...

  68. Analysis of active enhancers and direct androgen receptor target genes in VCaP prostate cancer cells BioProject

    ID: PRJNA329137

    Keywords: Other

    Access Type: download

  69. Suppression of androgen receptor mediated gene expression by a sequence-specific DNA binding polyamide GEMMA

    ID: 489

    Keywords: functional genomics

    Description: Androgen Receptor (AR) is essential for the growth and progression of prostate cancer in both hormone-sensitive and hormone-refract...

  70. Transcription profiling by array of human LNCaP prostate cancer cells after growth with dihydrotestosterone and treatment with polyamide ArrayExpress

    ID: E-GEOD-7708

    Description: Androgen Receptor (AR) is essential for the growth and progression of prostate cancer in both hormone-sensitive and hormone-refract...

  71. TALEN-Engineered AR Gene Rearrangements Reveal Endocrine Uncoupling of Androgen Receptor in Prostate Cancer OmicsDI

    ID: E-GEOD-49196

    Date Released: 09-26-2013

    Description: ent addressed the question of whether full length Androgen receptor and Androgen Receptor variant ARv567es have similar transciptional activities. The transcriptomes of R1-A...

  72. TALEN-Engineered AR Gene Rearrangements Reveal Endocrine Uncoupling of Androgen Receptor in Prostate Cancer ArrayExpress

    ID: E-GEOD-49196

    Description: ent addressed the question of whether full length Androgen receptor and Androgen Receptor variant ARv567es have similar transciptional activities. The transcriptomes of R1-A...

  73. Dihydrotestosterone induced changes in gene expression in immortalized human meibomian gland epithelial cells ArrayExpress

    ID: E-GEOD-18091

    Description: Genome-wide analysis of dihydrotestosterone (DHT) induced changes in gene expression in immortalized human meibomian gland epithelial cells. Analysis of regulation of immortalized ...

  74. A molecular and phenotypic integrative approach to identify a no effect dose level for anti-androgen induced testicular toxicity BioProject

    ID: PRJNA139641

    Keywords: Transcriptome or Gene expression

    Access Type: download

  75. LNCaP cells in response to DHT stimulation and inhibition/knockdown of TOPO2B ArrayExpress

    ID: E-GEOD-19445

    Description: t to ascertain whether TOP2β is required for DHT induced androgen receptor target gene expression. We investigated the effect of pharmacological inhibition or RNA interference-mediated depletion of T...

  76. LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs [GRO-seq I] BioProject

    ID: PRJNA207829

    Keywords: Transcriptome or Gene expression

    Access Type: download

  77. Genome-wide expression profiling of Hic-5 knockdown in PshTert-AR human myofibroblasts ArrayExpress

    ID: E-GEOD-47203

    Description: ect of the co-regulator Hic-5 (TGFB1I1) on global androgen receptor transcriptional activity in PShTert-AR prostate fibroblast cells with view to further elucidating the broader biological role of Hic...

  78. Leptin dependent control of testosterone regulated hepatic lipid metabolism ArrayExpress

    ID: E-GEOD-23941

    Description: Population based studies have established that androgen deficiency in males correlates with type 2 diabetes, visceral adiposity, and metabolic syndrome. Androgen

  79. Expression correlates of the full-length androgen receptor and its splicing variants ArrayExpress

    ID: E-GEOD-36549

    Description: Continued androgen receptor (AR) signaling is an established mechanism underlying castration-resistant prostate cancer (CRPC), and suppressio...

  80. LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs [ChIRP-seq] BioProject

    ID: PRJNA207830

    Keywords: Other

    Access Type: download

  81. NDRG1 siRNA and overexpression in breast cell lines BioProject

    ID: PRJNA154295

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: N-myc downstream-regulated gene 1 (*NDRG1*) is induced by cellular stress such as hypoxia and DNA damage, and in humans, germ line mutations cau...
  82. LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs [GRO-seq II] BioProject

    ID: PRJNA207828

    Keywords: Transcriptome or Gene expression

    Access Type: download

  83. Transcription profiling of mouse 15P-1 Sertoli cell clones stably transfected with mouse Rhox5-expression vector reveals androgen-Induced OmicsDI

    ID: E-GEOD-18785

    Date Released: 05-02-2014

    Description: identify Rhox5-regulated genes, we generated 15P-1 Sertoli cell clones expressing physiological levels of Rhox5 from a stably transfected expression vector. Microarray analysis identified many genes altered in expression in response to Rhox5, including those encoding proteins controlling cell cycle regulation, apoptosis, metabolism, and cell-cell interactions. Fifteen of these Rhox5-regulated genes were chosen for further analy...

  84. Transcription profiling of mouse 15P-1 Sertoli cell clones stably transfected with mouse Rhox5-expression vector reveals androgen-Induced ArrayExpress

    ID: E-GEOD-18785

    Description: identify Rhox5-regulated genes, we generated 15P-1 Sertoli cell clones expressing physiological levels of Rhox5 from a stably transfected expression vector. Microarray analysis identified many genes altered in expression in response to Rhox5, including those encoding proteins controlling cell cycle regulation, apoptosis, metabolism, and cell-cell interactions. Fifteen of these Rhox5-regulated genes were chosen for further analy...

  85. An Integrated Network of Androgen Receptor and TMPRSS2-ERG Gene Fusion in Prostate Cancer Progression (II) ArrayExpress

    ID: E-GEOD-14092

    Description: Androgen receptor (AR) is a transcription factor that plays a central role in the growth and development of the normal prostate and...

  86. Induced Pluripotency of Human Prostatic Epithelial Cells ArrayExpress

    ID: E-GEOD-45469

    Description: Induced pluripotent stem (iPS) cells are a valuable resource for discovery of epigenetic changes critical to cell type-specific dif...

  87. Dryad Dryad

    DateIssued: 01-25-2017

    Description: eus, of the western Mediterranean: Aigues-Mortes (AIG), southern France (N 43° 33’, E 4° 11’); Fuente de Piedra (FDP), southern Spain (37° 06’N, 04° 45’W) and the heavily polluted Odiel marshes (ODI), southern Spain (37º 17′ N, 06º 55′ W)....

  88. Transcription profiling of human LNCaP prostate cancer cells to investigate the effect of HDAC inhibitors on expression of androgen induced genes ArrayExpress

    ID: E-GEOD-9000

    Description: Elevated levels of androgen receptor (AR) in prostate cancer confer resistance to current antiandrogens and play a causal role in disease progression ...

  89. Transcription profiling of human prostate cancer cell line PC3 cells (low in PURa expression) stably over-expressing PUR reveals aPUR alpha protein in... ArrayExpress

    ID: E-GEOD-14464

    Description: Following androgen ablation treatment for advanced prostate cancer, almost all men relapse after a period of initial response to therapy, whi...

  90. Identification of EP4 as a Potential Target for the Treatment of Castration-Resistant Prostate Cancer Using a Novel Xenograft Model BioProject

    ID: PRJNA126897

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: te cancer, KUCaP-2, which expresses the wild-type androgen receptor (AR) and which produces the prostate-specific antigen (PSA). In this model, tumors regress soon after castration, but then reproducibly restore their ability to proliferate after 1 to 2 months without AR mutation, mimicking the clinical behavior of CRPC. In the present study, we used this model to identify novel therapeutic targets for CRPC. Evaluating ...
  91. "Drug-seq": An Approach to Identify the Genomic Targets of Chemicals Identified by Functional Phenotypic Screens [GRO-seq] ArrayExpress

    ID: E-GEOD-55903

    Description: ing for inhibitors of ligand and genotoxic stress-induced translocations in prostate cancer cells. Based on synthesis of a derivatized form of SD70 that permits its application for a ChIP-seq-like approach, referred to as Drug-seq, we were next able to efficiently map the genome-wide binding locations of this small molecule, revealing that it larg...

  92. Transcription profiling by array of human prostate cancer xenograft tissue at different stages of growth OmicsDI

    ID: E-GEOD-21887

    Date Released: 05-02-2014

    Description: te cancer, KUCaP-2, which expresses the wild-type androgen receptor (AR) and which produces the prostate-specific antigen (PSA). In this model, tumors regress soon after castration, but then reproducibly restore their ability to proliferate after 1 to 2 months without AR mutation, mimicking the clinical behavior of CRPC. In the present study, we used this model to identify novel therapeutic targets for CRPC. Evaluating ...

  93. "Drug-seq": An Approach to Identify the Genomic Targets of Chemicals Identified by Functional Phenotypic Screens [Drug-seq] ArrayExpress

    ID: E-GEOD-55901

    Description: ing for inhibitors of ligand and genotoxic stress-induced translocations in prostate cancer cells. Based on synthesis of a derivatized form of SD70 that permits its application for a ChIP-seq-like approach, referred to as Drug-seq, we were next able to efficiently map the genome-wide binding locations of this small molecule, revealing that it larg...

  94. Gene Expression in Castration-Resistant C4-2 Cells after AR Knockdown ArrayExpress

    ID: E-GEOD-13332

    Description: e most common, lethal malignancy in men. Although androgen withdrawal therapies are used to treat advanced disease, progression to a castration-resistant, end-stage is the usual outcome. In this study, ...

  95. CBS News/New York Times Poll: Recession/Economy Dataverse

    Description: issues and topics: Barack Obama job performance (1); direction of country (1); Barack Obama handling issues (4); Congress job performance (1); economic conditions (3); most i...

    Person: CBS News and The New York Times

    Release Date: 12-21-2010

  96. Testosterone-induced persistent dysregulations and transdifferentiation to exocrine pancreas in the female liver BioProject

    ID: PRJNA109813

    Keywords: Transcriptome or Gene expression

    Access Type: download

  97. mRNA profiling by androgen-induced tumor suppressor U19/EAF2 in the mouse prostate U19/EAF2 knockout ArrayExpress

    ID: E-GEOD-34511

    Description: To elucidate potential mechanisms of U19/EAF2 action, we performed cDNA microarray analysis and identified 202 mRNA transcripts regulated by U19/EAF2 ...

  98. Selenomethionine induced transcriptional programs in human prostate cancer cells ArrayExpress

    ID: E-GEOD-8769

    Description: w cytometry analysis showed that selenomethionine induced G2/M arrest in LNCaP at low concentrations. Selenomethionine also affected expression levels of 35 known androgen responsive genes and 18 of these transcripts showed changes that were the inverse of those seen after androgen stimulation. At high concentrations selenomethionine decreased prostate specific antigen promoter driven luciferase expression. CONCLUSIONS: Selenomethionine modulates transcript levels of genes involved in a number of biological processes, including cell cycle/apoptosis androgen signaling, signal transduction and transcriptional regulation. Although the pathways affected paralleled in many ways those that are modulated by methylselenic acid, distinct differences in transcript patterns and effects on cell cycle regulation suggest that different selenium compounds could exert unique effects in prostate cells. Groups of assays that are related as part of a time series. Computed...

  99. LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs [GRO-seq I] ArrayExpress

    ID: E-GEOD-47805

    Description: ncer, PRNCR1 and PCGEM1, bind successively to the androgen receptor (AR) and strongly enhance both ligand-dependent and ligand-independent AR-mediated gene activation programs and proliferation in prostate cancer cells. Binding of PRNCR1 to the C-terminally acetylated AR on enhancers and its association with DOT1L appear to be required for recruitment of the second lncRNA, PCGEM, to the N-terminally methylated AR. Unexpectedly, recognition of the H3K4me3 pro...

  100. Genome-wide expression profiling of Hic-5 and TGFB in WPMY fibroblasts ArrayExpress

    ID: E-GEOD-47354

    Description: urs in PShTert-AR cells significantly altered the androgen regulation of approximately 1347 genes. The effect of Hic-5 knockdown was to suppress androgen regulation of approximately 85% of those transcripts, by either reducing androgen mediated repression or activition of gene expression. Isogenic WPMY-1 fibroblasts stably transfected with short-hairpin RNA against Hic-5 or transfe...


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