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  1. Oct4 binding and Histone modification profiling during OSKM-mediated 2nd reprogramming OmicsDI

    ID: E-GEOD-67520

    Date Released: 01-03-2016

    Description: Forced expression of four transcription factors Oct4,Sox2, Klf4 and Myc (OSKM) induces somatic cell reprogramming towards pluripotency. Major efforts ...

  2. Streptococcus suis 05ZY: control vs contact with hBMEC 1 h OmicsDI

    ID: E-GEOD-46961

    Date Released: 01-02-2016

    Description: The interactions of Streptocococcus suis (S.suis) with human microvascular endothelial cells (hBMEC) are important process for S.suis passage across h...

  3. Expression data from OSKM-mediated 2nd reprogramming cells and the corresponding iPS cell line OmicsDI

    ID: E-GEOD-67462

    Date Released: 01-03-2016

    Description: Forced expression of four transcription factors Oct4,Sox2, Klf4 and Myc (OSKM) induces somatic cell reprogramming towards pluripotency. Major efforts ...

  4. Cryptochromes interact directly with PIFs to control plant growth in limiting blue light OmicsDI

    ID: E-GEOD-68193

    Date Released: 01-01-2016

    Description: Sun-loving plants have the ability to detect and avoid shading through sensing of both blue and red light wavelengths. Higher plant cryptochromes (CRY...

  5. BCOR controls maintenance of haematopoietic stem cell quiescence and regulates myeloid cell proliferation and differentiation [Illumina] OmicsDI

    ID: E-GEOD-69620

    Date Released: 01-01-2016

    Description: BCOR is a component of a variant Polycomb group repressive complex 1 (PRC1) complex. Recently, we and others reported recurrent somatic BCOR loss-of-f...

  6. Vascular niche induction of hematopoietic progenitors from pluripotent stem cells OmicsDI

    ID: E-GEOD-64644

    Date Released: 01-01-2016

    Description: Pluripotent stem cells (PSC) represent an alternative source of hematopoietic stem cells (HSCs). Clinical translation is impeded by limited engraftmen...

  7. Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (II) OmicsDI

    ID: E-GEOD-70613

    Date Released: 01-02-2016

    Description: In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for t...

  8. Mdm2 enhances stemness-promoting chromatin modifications through the Polycomb Repressor Complex 2 in a p53-Independent Manner [hMSC microarray] OmicsDI

    ID: E-GEOD-73601

    Date Released: 01-02-2016

    Description: The Mdm2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functions. Here we report that Mdm2 is required for the ...

  9. Models of Human Core Transcriptional Regulatory Circuitries OmicsDI

    ID: E-GEOD-76181

    Date Released: 12-27-2015

    Description: A small set of core transcription factors (TFs) dominates control of the gene expression program in embryonic stem cells and other well-studied cellul...

  10. G72 overexpression in U87 cells OmicsDI

    ID: E-GEOD-67704

    Date Released: 01-01-2016

    Description: G72 is a susceptible gene for schizophrenia. No matter genetic variation or serum levels, G72 has been recognized as a biomarker for schizophrenia. In...

  11. The effects of aging on circadian patterns of gene expression in the human prefrontal cortex OmicsDI

    ID: E-GEOD-71620

    Date Released: 01-02-2016

    Description: With aging, significant changes in circadian rhythms occur, including a shift in phase toward a “morning” chronotype and a loss of rhythmicity in ...

  12. ERK activation, gene dysregulations and cell transformation at submicromolar doses of Cr6+ in C3H10T1/2 and BALB/c 3T3 cells: interaction with Lipoic ... OmicsDI

    ID: E-GEOD-43156

    Date Released: 01-02-2016

    Description: The molecular mechanism of Cr6+ carcinogenicity is not well understood. Studies advocate a key involvement of the altered cytogenomics and dysregulate...

  13. The homeobox transcription factor Nkx2-1 regulates microRNAs controlling downstream gene silencing in lung epithelial cells (mRNA) OmicsDI

    ID: E-GEOD-47054

    Date Released: 12-26-2015

    Description: Cell-specific gene expression is achieved by a combination of mechanisms including transcriptional and post-transcriptional regulation. The transcript...

  14. Synergistic activity of BET protein antagonist-based combinations in Mantle Cell Lymphoma cells sensitive or resistant to ibrutinib OmicsDI

    ID: E-GEOD-70651

    Date Released: 01-02-2016

    Description: To determine the global transcriptome changes in mantle cell lymphoma cells following treatment with the BET bromodomain antagonist, JQ1 Mantle Cell L...

  15. Hormetic shifting of redox environment by the ROS-producing polyphenol resveratrol protects cells from oxidative stress OmicsDI

    ID: E-GEOD-72119

    Date Released: 01-02-2016

    Description: Resveratrol is a natural product that has gained tremendous interest due to multiple reported health-beneficial effects. However, the underlying mecha...

  16. CodeLink Mouse Whole Genome Bioarray data from hematopoietic stem cells (HSCs) of miR-125a (+/+) wild-type and miR-125a knockout mice with myeloprolif... OmicsDI

    ID: E-GEOD-69621

    Date Released: 01-01-2016

    Description: miR-125a knockout mice develop myeloproliferative disorder (MPD). To investigate the molecular mechanisms of MPD induced by the loss of miR-125a, gene...

  17. Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells OmicsDI

    ID: E-GEOD-66796

    Date Released: 12-26-2015

    Description: The human liver contains multiple cell types whose epigenetic patterns are undetermined. We examined the promoter methylome of purified and uncultured...

  18. Gene expression of 7 day combinatorial yohimbine and imipramine treated rat hippocampi OmicsDI

    ID: E-GEOD-61301

    Date Released: 01-03-2016

    Description: Rats treated on 7 consecutive days with either 2 injections of vehicle (Ctl) (DMSO for yohimbine, saline for imipramine) or Y+I (2mg/kg Yohimbine + 20...

  19. Cumulative low doses of the organic pesticide rotenone in the adult rat substantia nigra pars compacta OmicsDI

    ID: E-GEOD-22364

    Date Released: 01-02-2016

    Description: Adult male Sprague Dawley rats (5 month-old at the beginning of the study) were subcutaneously exposed to 0.5 mg.kg/d rotenone or the corresponding so...

  20. Global Analysis of the Transcriptional Response of Chinese cabbage (Brassica rapa ssp. pekinensis) to Methyl Jasmonate Reveals JA Signaling on Enhance... OmicsDI

    ID: E-GEOD-51363

    Date Released: 01-03-2016

    Description: We conducted a RNA-Seq analysis of MeJA-treated Chinese cabbage leaf transcriptome. Total 14,619,469 sequence reads were generated to produce 27,461 d...

  21. Gene expression changes in Apc-mutant mouse intestinal organoids 7 and 20 days after the induction of the Apc deletion OmicsDI

    ID: E-GEOD-47569

    Date Released: 01-02-2016

    Description: We isolated and selected intestinal adenoma organoids from Lgr5-EGFP-IRES-CreER; Apcflox/flox mice and added tamoxifen to induce the deletion of the A...

  22. 5-Day Gavage Study of Propylene glycol phenyl ether (PPH; CASRN 770-35-4) in Male Harlan Sprague Dawley Rats OmicsDI

    ID: E-GEOD-75656

    Date Released: 01-02-2016

    Description: The goal of this study was to characterize the potential toxicity and genomic benchmark dose of propylene glycol phenyl etherl in liver and kidney of...

  23. Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (I) OmicsDI

    ID: E-GEOD-70611

    Date Released: 01-02-2016

    Description: In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for t...

  24. Genome-wide mapping of TEL-AML1 targets in acute leukemia OmicsDI

    ID: E-GEOD-67519

    Date Released: 01-03-2016

    Description: Around 20-25% of childhood acute lymphoblastic leukemias carry the TEL-AML1 (TA) fusion gene. It is a fusion of two central hematopoietic transcriptio...

  25. Transcription profiling by high throughput sequencing of Arabidopsis estradiol-inducible tor-es mutant OmicsDI

    ID: E-MTAB-4132

    Date Released: 01-04-2016

    Description: To validate that the transcriptional program rapidly activated by PP242, WYE354, KU63794 and Torin2 was specifically associated with the complete inhi...

  26. Relative spatial homogeneity revealed by transcriptional profiling of multi-region medulloblastoma samples OmicsDI

    ID: E-GEOD-62803

    Date Released: 01-03-2016

    Description: Affymetrix Human Gene 1.1 ST Array profiling of 52 primary, multi-region medulloblastoma samples. Total RNA was extracted from primary medulloblastoma...

  27. Pharmacodynamic effects of GLP-1 agonist liraglutide in adolescent, prediabetic pigs OmicsDI

    ID: E-GEOD-56427

    Date Released: 01-02-2016

    Description: GLP-1 agonists are potent glucose-lowering agents, however, their effect on adolescent organisms needs to be clarified Transgenic pigs expressing a do...

  28. Assessment of ability of hTSLP to maintain primary CRLF2 B-ALL cells in a xenograft model in a state more similar to the parent leukemia OmicsDI

    ID: E-GEOD-74339

    Date Released: 01-02-2016

    Description: Xenograft models represent an excellent method for expanding primary leukemias, but their ability to preserve the gene expression profile of the paren...

  29. Transcriptome analysis of annotated coding genes and sORF under elevated CO2 OmicsDI

    ID: E-GEOD-49960

    Date Released: 01-02-2016

    Description: There are seedling samples (high CO2 exposure of 0h, 2h, 6h, 12h, 1d, 3d, 7d, 14d) with duplicates in two chambers. Arabidopsis WT (Col-0) seeds were ...

  30. Small RNAs in stress-related rice cultivars OmicsDI

    ID: E-GEOD-64651

    Date Released: 01-01-2016

    Description: In this study, we sequenced small RNA content from three different rice cultivars employing Illumina technology. More than 15 million reads were gener...

  31. Gene expression data from SW1990 cells stably expressing Fbw7 OmicsDI

    ID: E-GEOD-76443

    Date Released: 01-01-2016

    Description: Fbw7 plays a negative role in pancreatic cancer tumorigenesis and progression. To further clarify the function and mechanism that Fbw7 plays in pancre...

  32. circulating microRNA expression profiles of Kashin-Beck disease, osteoarthritis and rheumatoid arthritis OmicsDI

    ID: E-MTAB-3514

    Date Released: 12-30-2015

    Description: We compared the circulating microRNA expression profiles of KBD, osteoarthritis (OA), rheumatoid arthritis (RA) and healthy controls. Blood specimens ...

  33. Next generation sequencing of miRNAs in folic acid-induced kidney damage OmicsDI

    ID: E-GEOD-61328

    Date Released: 12-26-2015

    Description: We have used small RNA sequencing to measure the expression of all miRNAs present in the kidneys during the development of folic acid-induced kidney i...

  34. Cryptochromes interact directly with PIFs to control plant growth in limiting blue light OmicsDI

    ID: E-GEOD-59699

    Date Released: 01-02-2016

    Description: Sun-loving plants have the ability to detect and avoid shading through sensing of both blue and red light wavelengths. Higher plant cryptochromes (CRY...

  35. Expression data from S. cerevisiae OmicsDI

    ID: E-GEOD-33077

    Date Released: 01-02-2016

    Description: Low level of H3 Lys4 tri-methylation is a signature feature of silenced chromatin regions. We used microarray to analyze the contribution of S. cerev...

  36. Muscle expression of SOD1G93A modulates microRNA and mRNA expression pattern associated with the myelination process in the spinal cord of transgenic ... OmicsDI

    ID: E-GEOD-71194

    Date Released: 01-02-2016

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  37. Expression data of caerulein-treated wild-type mice and KrasG12D-mutated mice at different stages of pancreatic regeneration after inflammatory injury OmicsDI

    ID: E-GEOD-65146

    Date Released: 01-10-2016

    Description: Consecutive caerulein injections induce an acute pancreatitis in mice. Here, we recorded gene expression levels at different stages of pancreatic reg...

  38. Gene expression profiling of L-540, SUP-HD1, KM-H2 and L-428 Hodgkin lymphoma cell lines after in vitro and in vivo treatment with the dual PI3K/ERK i... OmicsDI

    ID: E-GEOD-58899

    Date Released: 01-10-2016

    Description: Disease relapse and resistance to chemotherapy represent challenging issues in a subset of Hodgkin Lymphoma (HL) patients. Activity and mechanism(s) o...

  39. Haploinsufficiency of interstitial genes between TMPRSS2 and ERG contributes to prostate tumorigenesis OmicsDI

    ID: E-GEOD-63070

    Date Released: 01-11-2016

    Description: TMPRSS2-ERG gene fusions that are frequently identified in prostate cancer can be generated either through chromosomal translocation or via interstiti...

  40. Transcription profiling by high throughput sequencing of maize seedlings segregating for gl3, a recessive mutant involved in the accumulation of epicu... OmicsDI

    ID: E-MTAB-4234

    Date Released: 01-11-2016

    Description: Bulked segregant analysis (BSA) is an efficient method to rapidly and efficiently map genes responsible for mutant phenotypes. This procedure, however...

  41. Expression data of SHSY5Y cells after cocaine exposure OmicsDI

    ID: E-GEOD-71939

    Date Released: 01-10-2016

    Description: The aim of the study was to evaluate cocaine-induced changes in gene expression in a dopaminergic model. Cocaine reward and reinforcing effects are me...

  42. Transcriptional analysis of quorum sensing null strain in Yersinia pestis CO92 at 30°C OmicsDI

    ID: E-GEOD-20217

    Date Released: 01-10-2016

    Description: Yersinia pestis is the etiology of plague that is able to sense cell density by quorum sensing. The function of quorum sensing in Y.pestis is not clea...

  43. Genome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and ... OmicsDI

    ID: E-GEOD-72099

    Date Released: 01-10-2016

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  44. Gene expression data from mouse tracheal cells before and 48hrs after SO2 injury OmicsDI

    ID: E-GEOD-69058

    Date Released: 01-10-2016

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  45. QS wild type and Aldh1a1-/- preadipocytes 2015 OmicsDI

    ID: E-GEOD-69573

    Date Released: 01-10-2016

    Description: The goal of this study was to identify preadipocyte signature genes that are dependent in aldehyde dehydrogenase 1a1 (Aldh1a1) by comparison genomes o...

  46. A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproli... OmicsDI

    ID: E-GEOD-74729

    Date Released: 01-10-2016

    Description: Purpose: Seek for differential gene expression in vemurafenib-resistant A375 tumors vs. untreated controls to provide a rationale for resistance mecha...

  47. Contact inhibition controls miR-223 stabilization via p27kip1 expression OmicsDI

    ID: E-GEOD-45538

    Date Released: 01-11-2016

    Description: The control of cell cycle progression mostly relays on the concerted activity of cyclins, CDKs and CDKs inhibitor. Recent data demonstrated that micro...

  48. Expression data from 9-day-old and 21-day-old rat Sertoli cell. OmicsDI

    ID: E-GEOD-76448

    Date Released: 01-10-2016

    Description: 9-day-old Sertoli cells have a stronger proliferative activity compared with 21-day-old Sertoli cells. We used microarrays to detail the global progra...

  49. FissionNet OmicsDI

    ID: E-GEOD-74354

    Date Released: 01-11-2016

    Description: Splicing profiling of deletion strains compared to wild-type control 1 replicate for each WT/deletion comparison Splicing sensitive S. pombe microarra...

  50. Expression profile of HCT116 cells treated with TNF-α/IFN-ɣ, both TNF-α/IFN-ɣ and silibinin, and without treatment. OmicsDI

    ID: E-GEOD-64131

    Date Released: 01-11-2016

    Description: Expression profiling of HCT116 colon cancer cells with different treatments. Illumina HumanHT-12 V4.0 expression beadchip was used to obtain expressio...


Displaying 50 of 79,180 results for " "