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  1. Acute time course and dose-dependence analysis of the dexamethasone (Dex)-regulated transcriptome in human primary hepatocytes NURSA

    Keywords: hepatocytes 1° cells

    Description: Primary human hepatocytes were treated for 8 or 24 h with or without 12 - 300 µM Dex.

    ID: 10.1621/vRVgrWJQdg

  2. Time course analysis of the 17β-estradiol (17βE2)-dependent transcriptome in rat vagina NURSA

    Keywords: whole vagina

    Description: Vaginas were removed from ovariectomized 9 week old Sprague Dawley rats treated with or without 20 µg/kg body weight 17βE2 for 6 h, 3 d or 5 d.

    ID: 10.1621/XEkvPCKRIr

  3. Analysis of the Cav1-regulated transcriptome in mouse heart NURSA

    Keywords: whole heart

    Description: Hearts were collected from 5-6 month old Caveolin 1 (Cav1) knockout or wild-type C57BL/J6 mice.

    ID: 10.1621/SFqc79nNa9

  4. Transcriptomic analysis of TNFα- and 17β-estradiol (17βE2)-treated MCF-7 cells NURSA

    Keywords: epithelium MCF-7 cells

    Description: Human MCF-7 breast cancer cells were treated with or without a combination of 10 nM 17βE2 and 10 ng/ml TNF for 2 h.

    ID: 10.1621/dErIbHBCBE

  5. Analysis of the rosiglitazone (Rosi)-regulated transcriptome in mouse aorta NURSA

    Keywords: other aorta whole

    Description: C57BL/6J male mice were treated with or without 25 mg/kg body weight/day Rosi via oral gavage for 21 d. Mice were sacrificed and the aorta removed.

    ID: 10.1621/dEYWKlZ72H

  6. Analysis of the dexamethasone (Dex) and 13 cis retinoic acid (13cRA)-dependent transcriptomes in immortalized mouse oligodendroglial cells NURSA

    Keywords: other neuroglia oligodendrocytes Oli-neu cells

    Description: Oli-neu immortalized mouse oligodendroglial cells were differentiated in the presence or absence of 1 µM 13cRA or 1 µM Dex for 10, 24, or 72 h..

    ID: 10.1621/ydpYtHGZLe

  7. Analysis of the androgen receptor (AR/Ar) and Utp14b-regulated transcriptomes in mouse testis NURSA

    Keywords: other whole testis

    Description: Testes were removed from 12 week old Sertoli cell-selective AR knockout mice on the jsd background with jsd mice serving as controls. Juvenile spermat...

    ID: 10.1621/TobZsNzPJU

  8. Analysis of the effect of low dose arsenic on the dexamethasone (Dex)-regulated hepatic transcriptome in mice NURSA

    Keywords: whole liver

    Description: Liver was isolated from C57BL/6J male mice fed the purified AIN-76A lab diet and injected for 8 h with or without 1 mg/kg Dex alone or in combination ...

    ID: 10.1621/xUvgILfCdT

  9. Analysis of the Tailless (TLX/NR2E1)-regulated transcriptome in human U251 astrocytoma cells NURSA

    Keywords: other neuroglia astrocytoma U251 cells

    Description: Human U251 astrocytoma cells were transiently transfected for 72 h with TLX/NR2E1 siRNA or negative control siRNA. Cells were subsequently treated for...

    ID: 10.1621/THQSasTa8U

  10. Strain-dependent analysis of the hepatic transcriptome in 2,3,7,8-tetrachlorodibenzodioxin (TCDD)-treated mice NURSA

    Keywords: whole liver

    Description: Liver was isolated from female 7 week old BALB/cAnN, C3H/HeN, CBA/JN mice treated with 40 UKBW TCDD or vehicle for 24 h.

    ID: 10.1621/RSlwUmE8QS

  11. Analysis of the fexaramine-dependent transcriptome in human HepG2 cells stably expressing mouse farnesoid X receptor (FXRα/Nr1h4) NURSA

    Keywords: epithelium HepG2 cells

    Description: Human HepG2 liver cancer cells stably expressing mouse FXRα/Nr1h4 were treated for 12 h with 1 µM fexaramine or vehicle.

    ID: 10.1621/Y5uY9kSu0E

  12. Analysis of selective estrogen receptor modulator (SERM)-regulated transcriptomes in MCF-7 cells NURSA

    Keywords: epithelium MCF-7 cells

    Description: Human MCF-7 breast cancer cells grown with charcoal-stipped FBS media were treated for 24 h with vehicle or different combinations of 17β-estradiol (...

    ID: 10.1621/c3DcUv6RKX

  13. Analysis of the Bromo Adjacent Homology Domain Containing 1 (Bahd1)-dependent transcriptome in mouse embryonic fibroblasts NURSA

    Keywords: embryonic

    Description: Mouse embryonic fibroblasts (MEFs) were isolated from Bahd1 knockout and wild-type embryos.

    ID: 10.1621/No31vwqB3O

  14. Transcriptomic profiling of bisphenol A (BPA)-treated human mammosphere-derived epithelial cells NURSA

    Keywords: epithelium mammospheres

    Description: Human mammosphere-derived epithelial cells were pre-exposed with and without 4 nM BPA for 3 weeks.

    ID: 10.1621/7YAeiRdIMq

  15. Transcriptomic profiling of the dexamethasone (Dex)-regulated transcriptome in mouse jejunum NURSA

    Keywords: whole jejunum

    Description: Jejunum was isolated from C57BL/6J mice treated for 2 h with 0.4 µg/g Dex or vehicle on postnatal day 8.

    ID: 10.1621/r2MylO4tC8

  16. Transcriptomic profiling of all-trans retinoic acid (ATRA)-treated JW0111 cells NURSA

    Keywords: chondrocytes JW0111 cells

    Description: Human chondrocyte JW0111 cells were treated with and without 1 µM ATRA for 48 h.

    ID: 10.1621/NsJpXgWzO6

  17. Acute time course and dose-dependence analysis of the 17α-ethinylestradiol (17αEE2)-regulated transcriptome in rat primary hepatocytes NURSA

    Keywords: hepatocytes 1° cells

    Description: Primary rat hepatocytes were treated for 2 - 24 h with or without 12 - 300 µM 17αEE2.

    ID: 10.1621/7G5gdOVcC2

  18. Analysis of the in utero 17β-estradiol (17βE2)-regulated transcriptome in wild type and estrogen receptor-α (ERα/Esr1) null mouse testes NURSA

    Keywords: other whole testis

    Description: Pregnant wild type or ERα/Esr1 knockout mice were injected with or without 6 mg/kg body weight 17βE2 between 13 dpc and 18 dpc. Females were killed ...

    ID: 10.1621/G5aD7mLagy

  19. Analysis of the aldehyde dehydrogenase 1A2 (Aldh1a2)-regulated embryonic transcriptome NURSA

    Keywords: whole embryo

    Description: The anterior part of the head (including the anterior forebrain, optic vesicles, and overlying tissues) at the 14 somite stage and the posterior tissu...

    ID: 10.1621/KuoCZwZU7S

  20. Anaysis of the Ppargc1a-dependent renal transcriptome in a mouse model of diet-induced obesity NURSA

    Keywords: whole kidney

    Description: Kidney was isolated from nephron-specific inducible Ppargc1a KO and WT male C57BL/6 mice fed a normal or high fat diet (HFD; 60% calories as fat) for ...

    ID: 10.1621/XxJjPandlz

  21. Acute time course and dose-dependence analysis of the clofibrate (Clofib)-regulated transcriptome in rat kidney NURSA

    Keywords: whole kidney

    Description: Kidneys were isolated from rats treated for 3 - 24 h with or without 30 mg - 300 mg/kg bw/d Clofib.

    ID: 10.1621/n3PkpDzRsv

  22. Analysis of the hepatocyte nuclear factor 4-α variant 2 (HNF4α/Hnf4a-2) and HNF4α-8-dependent transcriptomes in rat pancreatic beta cells NURSA

    Keywords: islets beta cells INS1 cells

    Description: Rat INS-1 pancreatic beta-cells were stably transfected with tetracycline-inducible vectors encoding (1) HNF4α/Hnfa-2; or (2) HNF4α/Hnfa-8 and cultu...

    ID: 10.1621/g419TFD45e

  23. Time course analysis of the Tamoxifen (Tam)-regulated transcriptome in rat uterus NURSA

    Keywords: whole uterus

    Description: Immature ovariectomized female Sprague Dawley rats were treated with and without a single dose of 100 µg/kg body weight Tam for prior to removal of u...

    ID: 10.1621/gRraG8VHXv

  24. Time course transcriptomic analysis of thyroid hormone (T3) and 9-cis retinoic acid (9cRA)-treated human erythroid progenitor cells NURSA

    Keywords: erythrocytes

    Description: Erythroid progenitor cells obtained from human cord blood were left undifferentiated or differentiated into red blood cells in the presence of 100 nM ...

    ID: 10.1621/s13GtMg42i

  25. Analysis of the arylhydrocarbon receptor (Ahr)-regulated hepatic transcriptome in 2,3,7,8-tetrachlorodibenzodioxin (TCDD)-treated mice NURSA

    Keywords: whole liver

    Description: Liver was isolated from male C57BL/6J 15 week old Ahr knockout and wild-type mice treated with and without 1000 UKBW TCDD for 19 h.

    ID: 10.1621/P9XIQWjG4I

  26. Time course transcriptomic analysis of progesterone (P4)-treated mouse mammary gland NURSA

    Keywords: other whole mammary gland

    Description: Ovariectomized nuliparous Balb/c mice 8-weeks of age were treated with a single subcutaneous injection of 1 mg P4 or vehicle. Mice were sacrificed an...

    ID: 10.1621/4rM9Zl427P

  27. Analysis of the steroid receptor coactivator-2 (GRIP1/NCOA2)-dependent targeted metabolome in decidualizing primary human endometrial stromal cells un... NURSA

    Keywords: endometrium stroma 1° cells

    Description: Decidualizing primary human endometrial stromal cells were transfected with GRIP1/NCOA2 siRNA or a negative control siRNA and subjected to a glycolyti...

    ID: 10.1621/xOQ2pzR39G

  28. Transcriptomic profiling of dexamethasone (Dex)-treated human female synovial fibroblasts NURSA

    Keywords: fibroblasts synovial

    Description: Cultured primary synovial fibroblasts from females with rheumatoid arthritis were treated with 100 nM Dex for 16 h.

    ID: 10.1621/E6nnvDcx1D

  29. Analysis of the Fulvestrant (Fulv)-dependent transcriptomes in two long-term estrogen-deprived breast cancer cell lines, MCF-7 and HCC1428 NURSA

    Keywords: epithelium MCF-7 LTED cells

    Description: Human long-term estrogen-deprived breast cancer cells (MCF-7 and HCC1428) were treated with or with 1 µM Fulv for 48 h.

    ID: 10.1621/Hxz5Xa79WN

  30. Time course analysis of the methylprednisolone (MePred)-regulated transcriptomine in rat skeletal muscle NURSA

    Keywords: gastrocnemius whole

    Description: Adrenalectomized male Wistar rats weighing 225-250 g were treated with or without 50 mg/kg MePred via jugular-vein cannulation for a range of time per...

    ID: 10.1621/VT4ypwgof6

  31. Analysis of the synthetic selective thyroid hormone receptor modulator, GC1, in HepG2 hepatocellular carcinoma cells NURSA

    Keywords: epithelium HepG2 cells

    Description: Human HepG2 hepatocellular carcinoma cells were treated with 10 nM T3 or 10 nM GC1 for 24 h.

    ID: 10.1621/lb4zaYEkrT

  32. Analysis of the medroxyprogesterone acetate (MPA)-regulated transcriptome in pregnant mouse cervix NURSA

    Keywords: other cervix whole

    Description: E15 timed pregnant CD-1 mice were treated with or without 1 mg MPA for 48 h after which cervical tissue was collected.

    ID: 10.1621/8hYPylhna7

  33. Analysis of the dexamethasone (Dex) and all-trans retinoic acid (ATRA)-dependent transcriptomes in mouse lung NURSA

    Keywords: whole lung

    Description: Postnatal day 3 or 4 C57BL/6 mice were injected subcutaneously with 0.7 µg Dex, 1 mg/kg/body weight ATRA or vehicle, and lungs were removed 6 h later...

    ID: 10.1621/ipCKYp9Rxv

  34. Analysis of the peroxisome proliferator-activated receptor-γ (PPARγ/Pparg)-regulated transcriptome during adipogenesis in mouse 3T3-L1 adipocytes NURSA

    Keywords: WAT adipocytes 3T3-L1-derived

    Description: 3T3-L1 preadipocytes were treated with or without a standard differentiation coctail for 14 days to induce adipocyte differentiation, then transfected...

    ID: 10.1621/nWjv1UhrEE

  35. Time course transcriptomic analysis of all-trans retinoic acid (ATRA)-treated mouse dorsal neural tube explants NURSA

    Keywords: other neural crest 1° cells

    Description: Dorsal neural tube explants isolated from 8.5 dpc mouse embryos were treated with or without 1 µM ATRA for 6, 12, 24 or 48 h.

    ID: 10.1621/7OwbSiA6OW

  36. Analysis of the hepatocyte nuclear factor 4-α (HNF4α/Hnf4a)-regulated female mouse hepatic transcriptome NURSA

    Keywords: whole liver

    Description: Liver tissue was isolated from female 5-6 month old liver specific HNF4α/Hnf4a null mutant and wild-type C57BL/6 mice.

    ID: 10.1621/Dhhr3ZAvzL

  37. Analysis of the 17β-estradiol (17βE2) dependent transcriptome in MDA-MB-134VI human invasive lobular carcinoma breast cancer cells NURSA

    Keywords: epithelium MDA-MB-134VI cells

    Description: MDA-MB-134VI invasive lobular carcinoma breast cancer cell lines were treated with 1 nM 17βE2 or vehicle for 3 h and 24 h.

    ID: 10.1621/zEw5AnZuqQ

  38. Analysis of the receptor interacting protein-140 (RIP140/NRIP1)-dependent transcriptome in all-trans retinoic acid (ATRA)-treated NT2/D1 cells NURSA

    Keywords: pluripotent NT2-D1 cells

    Description: Human NT2/D1 embryonal carcinoma cells were transfected with control siRNA or anti-RIP140 siRNA and treated with or without 10 µM ATRA for 24 h.

    ID: 10.1621/2rZg95Zitd

  39. Comparison of the 17β-estradiol (17βE2)-regulated, time-dependent transcriptome between MDA-MB-231 cells stably expressing wild type estrogen recept... NURSA

    Keywords: epithelium MDA-MB-321 cells

    Description: 10 nM 17βE2 was administered for 2 h - 8 h to ERα/ESR1-negative breast cancer cells stably expressing wild-type ERα/ESR1 or the ERα/ESR1 (E203G/G2...

    ID: 10.1621/uA3Ei5ZNdj

  40. Analysis of the dexamethasone (Dex)-dependent transcriptome in A549 lung adenocarcinoma cells NURSA

    Keywords: epithelium A549 cells

    Description: Human A549 lung adenocarcinoma cells were treated with 3 µM RU486 for 48 h followed by 100 nM Dex for 6 h or Dex alone for 6 h.

    ID: 10.1621/xigKzGn1se

  41. Mutational analysis of the androgen receptor (AR/Ar)-regulated transcriptome in mouse skeletal muscle models of Kennedy disease/spinal bulbar muscular... NURSA

    Keywords: limb whole

    Description: Limb muscle was harvested from wild type mice and three models of Kennedy disease/spinal bulbar muscular atrophy: (1) AR113Q mice, a knockin line in w...

    ID: 10.1621/BuE2FppUS9

  42. Analysis of the peroxisome proliferator activated receptor-α (PPARα/Ppara)-dependent, Wy 14,643-regulated transcriptomes in mouse liver NURSA

    Keywords: whole liver

    Description: Liver was isolated from 3-5 month old wild type or PPARα/Ppara knockout male 129S1/SvImJ mice treated with or without 4 mg WY14643 for 6 h.

    ID: 10.1621/oMVF4xu9yU

  43. Analysis of the short heterodimeric partner (SHP/Nr0b2)-regulated, western or chow diet-specific transcriptomes in mouse liver NURSA

    Keywords: whole liver

    Description: Liver was isolated from SHP/Nr0b2 null mutant and wild-type male C57Bl/6 hsd mice fed a normal chow or western diet for 6 months.

    ID: 10.1621/HNoISovaG2

  44. Timecourse analysis of the 17β-estradiol (17βE2)-, genistein (Gen)-, and Fulvestrant (Fulv)-regulated, estrogen receptor-β (ERβ/ESR2)-dependent tr... NURSA

    Keywords: epithelium MCF-7 cells

    Description: Human MCF-7 breast cancer cells were transfected with an adenovirus expressing ERβ/ESR2 at a MOI of 20 for 48 h and then treated with a combination o...

    ID: 10.1621/JTNKFMkDSu

  45. Transcriptomic analysis of all-trans retinoic acid (ATRA)-, 16keto-estradiol (16KE2)- and 1,25-dihydroxyvitamin D3 (125DVD3)-treated HL-60 cells NURSA

    Keywords: myeloid lineage promyelocytes APL HL-60 cells

    Description: Human HL-60 promyelocytic cells were treated for 5 d with or without: (1) 1 µM ATRA; (2) 70 µM 16KE2; or (3) 100 nM 125DVD3.

    ID: 10.1621/P4lJ7avrZ8

  46. Analysis of the progesterone (P4) dependent transcriptome in mouse uterus NURSA

    Keywords: whole uterus

    Description: Uterus was isolated from ovariectomized mice treated with 1 mg P4 for 6 h.

    ID: 10.1621/2zH4dg8TfB

  47. Analysis of the estrogen receptor-α (ERα/ESR1) DNA-binding domain-independent transcriptome in 17β-estradiol (17βE2)-treated MDA-MB-231 cells NURSA

    Keywords: epithelium MDA-MB-321 cells

    Description: Human MDA-MB-231 breast cancer cells stably expressing a DNA-binding-deficient ERα/ESR1 mutant or empty vector were treated with 1 nM 17βE2 for 6 h....

    ID: 10.1621/bDZEEBPCde

  48. Analysis of the hepatocyte nuclear factor 4 receptor α (HNF4α/HNF4A)-regulated transcriptome in inflammatory human HepG2 cells NURSA

    Keywords: epithelium HepG2 cells

    Description: Human HepG2 liver cancer cells were treated for 18 h with or without a cytokine mixture to induce an inflammatory response, followed by transfection w...

    ID: 10.1621/CWhdLJd86i

  49. Analysis of the obese transcriptomic signature in subcutaneous white adipose tissue (WAT) in Pima Indians NURSA

    Keywords: WAT subcutaneous

    Description: Subcutaneous adipose tissue was obtained from female non-diabetic obese and lean Pima Indian subjects.

    ID: 10.1621/8Uyh5IBaft

  50. Analysis of the silent mating type information regulation 1 (Sirt1) and peroxisome proliferator-activated receptor α (PPARα/Ppara)-regulated transcr... NURSA

    Keywords: whole heart

    Description: Hearts were dissected from from male wild-type, and cardiac-specific Sirt1 or Sirt1-PPARα transgenic mice.

    ID: 10.1621/ZYLtb2Vvan


Displaying 50 of 931 results for " "