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  1. Parallel single-cell bisulfite- and RNA-sequencing link transcriptional and epigenetic heterogeneity OmicsDI

    ID: E-GEOD-74535

    Date Released: 12-26-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  2. Identification of drugs that enhance skin repair using dermal stem cell-based screens [Rat] OmicsDI

    ID: E-GEOD-73328

    Date Released: 12-26-2015

    Description: Here, we asked whether we could identify pharmacological agents that enhance endogenous stem cell function to promote skin repair, focusing on SKPs (s...

  3. Histone deacetylase inhibitors antagonize distinct pathways to suppress tumorigenesis of embryonal rhabdomyosarcoma. OmicsDI

    ID: E-GEOD-74970

    Date Released: 12-26-2015

    Description: Embryonal rhabdomyosarcoma (ERMS) is the most common soft tissue cancer in children and is characterized by myogenic differentiation arrest. The progn...

  4. Comparison of gene expression by sheep and human blood stimulated with the TLR4 agonists lipopolysaccharide and monophosphoryl lipid A [sheep] OmicsDI

    ID: E-GEOD-72558

    Date Released: 12-19-2015

    Description: 11,431 and 4,992 genes were determined in whole blood of healthy human volunteers and normal sheep, respectively following MPLA and LPS exposure Follo...

  5. Identifying transcription start sites and active enhancer elements using BruUV-seq OmicsDI

    ID: E-GEOD-75398

    Date Released: 12-26-2015

    Description: BruUV-seq utilizes UV light to introduce transcription-blocking DNA lesions randomly in the genome prior to bromouridine-labeling and deep sequencing ...

  6. Identification and characterization of MCF01A circular RNAs [RNA-seq] OmicsDI

    ID: E-GEOD-71195

    Date Released: 12-27-2015

    Description: Circular RNAs (circRNAs) are widespread circular forms of non-coding RNAs with largely unknown function. Because stimulation of mammary cells with the...

  7. Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease OmicsDI

    ID: E-GEOD-76105

    Date Released: 12-27-2015

    Description: Recent work has identified roles for environmental, genetic and epigenetic factors in AD risk. Motivated by suspected roles for epigenetic modificatio...

  8. Response to different types of stress converge in mitochondrial metabolism OmicsDI

    ID: E-MTAB-4044

    Date Released: 12-27-2015

    Description: The budding yeast Saccharomyces cerevisiae was used to study 9 different stress conditions in chemostat conditions at constant specific growth rate.

  9. TRANSCRIPTIONAL CHANGES IN HARD CLAM (MERCENARIA MERCENARIA) IN RESPONSE TO QPX DISEASE AND TEMPERATURE OmicsDI

    ID: E-GEOD-76182

    Date Released: 12-27-2015

    Description: Transcriptional profiling of different clam tissues (hemolymph and mantle) in response to QPX disease and temperautre Quahog Parasite Unknown (QPX) is...

  10. Gene expression profiling of tumor cells and M2 macrophages from WT mice and mice with deletion of integrin beta3 in macrophage lineage cells (b3KOM) OmicsDI

    ID: E-GEOD-75882

    Date Released: 12-27-2015

    Description: To better understand the impact of integrin beta3 signaling in myeloid cells on the tumor microenvironment, we compared the gene expression profiles o...

  11. A Systems Approach to Understanding Human Rhinovirus and Influenza Virus Infection OmicsDI

    ID: E-GEOD-71766

    Date Released: 12-26-2015

    Description: Human rhinovirus and influenza virus infections of the upper airway lead to colds and the flu and can trigger exacerbations of lower airway diseases i...

  12. A serum microRNA panel as potential biomarkers for hepatocellular carcinoma related with hepatitis B virus OmicsDI

    ID: E-GEOD-59418

    Date Released: 12-27-2015

    Description: Background: The identification of new high sensitivity and specificity markers for HCC are essential. We aimed to identify serum microRNAs for diagnos...

  13. Quantitative BrdU immunoprecipitation method demonstrates that Fkh1 and Fkh2 are rate-limiting activators of replication origins that reprogram replic... OmicsDI

    ID: E-GEOD-71050

    Date Released: 12-27-2015

    Description: The S. cerevisiae Forkhead Box (FOX) proteins, Fkh1 and Fkh2, regulate diverse cellular processes including transcription, long-range DNA interactions...

  14. RNA-seq for monitoring expression changes in absence of chromatin anchoring OmicsDI

    ID: E-GEOD-74067

    Date Released: 12-20-2015

    Description: RNA-seq for monitoring expression levels in mutants that do not anchor chromatin at the nuclear periphery. RNA-seq of depleted rRNA samples of early e...

  15. RNA Seq in wild type and zfs1 deficient C. albicans OmicsDI

    ID: E-GEOD-53073

    Date Released: 12-20-2015

    Description: Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins bind to AU-rich regions in the 3'-untranslated regions (UTR) of target...

  16. RNA Polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA Polymerase II OmicsDI

    ID: E-GEOD-62171

    Date Released: 12-20-2015

    Description: Release of promoter-proximal paused RNA polymerase II (Pol II) during early elongation is a critical step in transcriptional regulation in metazoan ce...

  17. Microarray-based transposon mapping analysis for identification of chlorhexidine resistance genes in Enterococcus faecium E1161 OmicsDI

    ID: E-MTAB-4173

    Date Released: 12-23-2015

    Description: Microarray-based Transposon Mapping (M-TraM) of E. faecium E1162 to identify conditionally essential genes, required for growth in the presence of chl...

  18. A microfluidic platform enabling single cell RNA-seq of multigenerational lineages OmicsDI

    ID: E-GEOD-74923

    Date Released: 12-26-2015

    Description: We introduce a microfluidic platform that enables off-chip single-cell RNA-seq after multigenerationa lineage tracking under controlled culture condit...

  19. LOXL2 dependent genes in RA induced mES differentiation OmicsDI

    ID: E-GEOD-65675

    Date Released: 12-26-2015

    Description: Our results indicate that oxidation of TAF10 by LOXL2 induces its release from its promoters, leading to a block in TFIID-dependent gene transcription...

  20. HITS-CLIP of cytoplasmic SLBP RNP OmicsDI

    ID: E-GEOD-61958

    Date Released: 12-19-2015

    Description: UV cross-linking and immunoprecipiatation with high throughput sequencing of cytoplasmic SLBP RNP Polyclonal α-SLBP antibody was used to immunoprecip...

  21. Functional characterization of hGRβ Isoform in mouse liver OmicsDI

    ID: E-GEOD-75740

    Date Released: 12-27-2015

    Description: We used AAV as a vector to deliver hGRβ to C57BL/6 mouse liver. We collected liver samples for microarray analysis to investigate any phenotype as we...

  22. The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells OmicsDI

    ID: E-GEOD-70106

    Date Released: 12-26-2015

    Description: BACKGROUND: Combination antiretroviral therapy (cART) is able to control HIV-1 viral replication, however long-lived latent infection in resting memor...

  23. Dual RNA-seq – sRNA profiling in various cell types OmicsDI

    ID: E-GEOD-67947

    Date Released: 12-20-2015

    Description: Bacteria possess many small noncoding RNAs whose regulatory roles in pathogenesis are little understood due to a paucity of macroscopic phenotypes in ...

  24. Expression data from Amacr knock-out mouse liver OmicsDI

    ID: E-GEOD-40085

    Date Released: 12-26-2015

    Description: Bile acids play multiple roles in vertebrate metabolism by facilitating lipid absorption in the intestine and acting as a signaling molecule in lipid ...

  25. mRNA/microRNA expression profiles of HCC or CCC patients' liver, together with those of non-tumor part tissues OmicsDI

    ID: E-GEOD-57555

    Date Released: 12-26-2015

    Description: 11 CCC and 5 HCC patients' tumor and non-tumor parts tissues are extracted. Then total RNA are purified from tissues and mRNA and miRNA profiles are m...

  26. Whole-genome saliva and blood DNA methylation patterns in individuals with a respiratory allergy OmicsDI

    ID: E-GEOD-73745

    Date Released: 01-09-2016

    Description: It has been suggested that the etiology of respiratory allergies (RA) can be partly explained by DNA methylation changes caused by adverse environment...

  27. Long non-coding RNAs display higher natural expression variability than protein-coding genes in healthy humans OmicsDI

    ID: E-GEOD-70390

    Date Released: 01-09-2016

    Description: Background: Long non-coding RNAs (lncRNAs) are increasingly implicated as gene regulators and may ultimately be more numerous than protein-coding gene...

  28. Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure – Identification of Regulatory Gene Network [proton] OmicsDI

    ID: E-GEOD-68875

    Date Released: 01-10-2016

    Description: We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 c...

  29. Gene expression in a 3-dimensional reconstructed human corneal epithelial tissue after near-infrared irradiation simulating solar near-infrared radiat... OmicsDI

    ID: E-GEOD-76500

    Date Released: 01-09-2016

    Description: To clarify the effects of near-infrared radiation, we assessed DNA microarray after water-filtered broad-spectrum near-infrared (1100-1800 nm together...

  30. Degradome sequencing analysis in developing wheat grains OmicsDI

    ID: E-GEOD-65798

    Date Released: 01-10-2016

    Description: We aimed to identify targets of miRNAs during wheat grain development by using degradome sequencing approach. Two degradome libraries were constructed...

  31. Gene expression data from mouse tracheal mesenchymal cells before and 48hrs after SO2 injury OmicsDI

    ID: E-GEOD-69057

    Date Released: 01-10-2016

    Description: The conducting airway epithelium of the rodent and human lung is underlaid by mesenchymal cells that include vasculature, smooth muscle, fibroblasts a...

  32. Transcription profiling of midbrain samples from Ezh2 knockout mouse embryos OmicsDI

    ID: E-GEOD-74538

    Date Released: 01-06-2016

    Description: Background: Precise spatiotemporal control of gene expression is essential for the establishment of correct cell numbers and identities during brain ...

  33. Identification of mir-342-3p functionally associated with transcriptional activity of MYC in lung cancer [cell culture] OmicsDI

    ID: E-GEOD-66758

    Date Released: 01-08-2016

    Description: Accumulating evidence indicates that altered miRNA expression is crucially involved in lung cancer development, but only little has been elucidated ab...

  34. MicroRNA expression profile of primary prostate cancer stem cells as a source of biomarkers and therapeutic targets OmicsDI

    ID: E-GEOD-59156

    Date Released: 01-09-2016

    Description: MicroRNA (miRNA) expression profiles were generated from prostate epithelial sub-populations, enriched from patient-derived benign prostatic hyperplas...

  35. Transcriptome-wide regulation of pre-mRNA splicing and expression by the RNA-binding protein Quaking during monocyte to macrophage differentiation [RN... OmicsDI

    ID: E-GEOD-74978

    Date Released: 01-09-2016

    Description: Expression levels of the RNA-binding protein Quaking (QKI) are low in monocytes of early, human atherosclerotic lesions, but abundant in macrophages o...

  36. Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells OmicsDI

    ID: E-GEOD-53510

    Date Released: 01-02-2016

    Description: We profile the expression pattern of human pulmonary microvascular endothelial cells (HPMECs) at different time points of hypoxic stress. Through mRNA...

  37. Transcription profiling by high throughput sequencing of somatic and reproductive tissues of Brassica rapa plants following heat shock stress exposure... OmicsDI

    ID: E-MTAB-4131

    Date Released: 01-07-2016

    Description: In the current study we have profiled changes in the transcriptome of somatic and reproductive tissues of B.rapa plants following heat shock stress ex...

  38. Regulation of blood group gene expression by miRNAs OmicsDI

    ID: E-GEOD-76526

    Date Released: 01-08-2016

    Description: To determine the miRNA expression pattern in RBCs, we isolated miRNA from RBCs of healthy blood donors, who were homozygous or heterozygous carriers o...

  39. Transcription profiling by high throughput sequencing of a maize IBM (Intermated B73×Mo17) RIL population derived from the cross of the inbred lines ... OmicsDI

    ID: E-MTAB-4227

    Date Released: 01-08-2016

    Description: Gene transcription is an essential step of gene function and transcriptome variation is of agronomical, ecological and evolutionary importance. To exp...

  40. FGFR signature OmicsDI

    ID: E-GEOD-73024

    Date Released: 01-08-2016

    Description: Drugs that target specific gene alterations have proven beneficial in the treatment of cancer. Because cancer cells have multiple resistance mechanism...

  41. A conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing OmicsDI

    ID: E-GEOD-74741

    Date Released: 01-09-2016

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  42. Ubiquitin-dependent turnover of MYC promotes loading of the PAF complex on RNA Polymerase II to drive transcriptional elongation (ChIP-seq) OmicsDI

    ID: E-GEOD-70001

    Date Released: 01-09-2016

    Description: The MYC transcription factor is an unstable protein and its turnover is controlled by the ubiquitin system. Ubiquitination enhances MYC-dependent tran...

  43. HT-project: Expression profiling after prolonged experimental febrile seizures suggests structural remodeling in the hippocampus OmicsDI

    ID: E-GEOD-66762

    Date Released: 01-09-2016

    Description: Febrile seizures are the most prevalent type of seizures among children up to 5 years of age (2-4% of Western-European children). Complex febrile seiz...

  44. Glucose Metabolic Remodeling through Phosphoenolpyruvate Carboxykinase Isoform 2 Regulates Prostate Cancer Cell Tumorigenicity OmicsDI

    ID: E-GEOD-76470

    Date Released: 01-09-2016

    Description: Patients with aggressive prostate cancer generally present with poor outcomes. Identifying the factors regulating prostate cancer aggressiveness may o...

  45. Expression data analysis from RPMI 8226 cells irraidated to C-ions. OmicsDI

    ID: E-GEOD-76471

    Date Released: 01-09-2016

    Description: Multiple Myeloma (MM) is an hematological malignancy. MM cells are resistant to X-ray irradiations. We irradiated RPMI 8226 cancer cells with C-ions, ...

  46. Expression data from C. elegans wild type, hlh-25 mutant and hlh-29 mutant strains OmicsDI

    ID: E-GEOD-65417

    Date Released: 01-10-2016

    Description: In Caenorhabditis elegans, the six proteins that make up the REF-1 family are HES homologs that act in both Notch dependent and Notch-independent path...

  47. A conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing [ChIP-chip] OmicsDI

    ID: E-GEOD-74740

    Date Released: 01-09-2016

    Description: Occupancy profiling of lysine 9 dimethylated histone H3 in fission yeast. Occupancy profiling of Red1, Mtl1, and Mmi1 proteins in fission yeast. Agile...

  48. The chicken erythrocyte epigenome OmicsDI

    ID: E-GEOD-75955

    Date Released: 01-10-2016

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  49. Transcription profiling by high throughput sequencing of Arabidospsis ref8-1, med5a/5b, and med5a/5b ref8-1 mutants OmicsDI

    ID: E-MTAB-4193

    Date Released: 01-07-2016

    Description: Mutation of the lignin biosynthetic gene REF8, which encodes p-coumaroylshikimate 3'-hydroxylase, causes widespread changes in gene expression in Arab...

  50. Transcription profiling by RNA-seq of fetal liver from poly(C) binding protein 2 (Pcbp2) knockout mice OmicsDI

    ID: E-GEOD-72491

    Date Released: 01-08-2016

    Description: RNA-binding proteins participate in a complex array of post-transcriptional controls essential to cell-type specification and somatic development. De...


Displaying 50 of 78,272 results for " "