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  1. A survey of human brain transcriptome diversity at the single cell level OmicsDI

    ID: E-GEOD-67835

    Date Released: 08-19-2015

    Description: We used single cell RNA sequencing on 466 cells to capture the cellular complexity of the adult and fetal human brain at a whole transcriptome level. ...

  2. Gene expression changes in a histone sprocket arginine mutant in histone H2A R78A OmicsDI

    ID: E-GEOD-68159

    Date Released: 08-19-2015

    Description: Examined gene expression changes in a histone H2A R78A mutant in Saccharomyces cerevisiae relative to wild-type cells. THe overall goal of this study ...

  3. Droplet barcoding for single cell transcriptomics applied to embryonic stem cells OmicsDI

    ID: E-GEOD-65525

    Date Released: 08-19-2015

    Description: Recently, RNA sequencing has achieved single cell resolution, but what is limiting is an effective way to routinely isolate and process large numbers ...

  4. Ten day time course of the effect of influenza A infection on mediastinal lymph node gene expression in mice OmicsDI

    ID: E-GEOD-57453

    Date Released: 08-19-2015

    Description: These data were generated as part of a study to model gene regulatory networks influenced by influenza infection. Other tissue compartments included i...

  5. Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition OmicsDI

    ID: E-GEOD-68808

    Date Released: 08-19-2015

    Description: Pancreatic ductal adenocarcinoma (PDAC) is associated with accumulation of particular oncogenic mutations and recent genetic sequencing studies have i...

  6. A novel small-molecule inhibitor of STAT5A/STAT5B with therapeutic potential for prostate cancer and CML OmicsDI

    ID: E-GEOD-61312

    Date Released: 08-19-2015

    Description: We assessed the gene expression profiles induced by both genetic and pharmacological knockdown of Stat5a/b in CML cells. Stat5 was suppressed in K562 ...

  7. Response of HK-2 cells to stimulation with IL6 and TNF-alpha (90 minutes) OmicsDI

    ID: E-GEOD-68940

    Date Released: 08-19-2015

    Description: Abstract: Human kidney function declines with age, accompanied by stereotyped changes in gene expression and histopathology, but the mechanisms under...

  8. RNA-sequencing in OS-RC-2 cells under the knockdown of Arkadia or ESRP2 OmicsDI

    ID: E-GEOD-66741

    Date Released: 08-19-2015

    Description: Tumor-specific alternative splicing is implicated in the progression of cancer, including clear cell renal cell carcinoma (ccRCC). Using ccRCC RNA-seq...

  9. A human fetal transcriptional atlas OmicsDI

    ID: E-GEOD-66302

    Date Released: 08-19-2015

    Description: Gene expression is highly dynamic during fetal development and determines tissue specification and function. In humans, the transcriptional profile of...

  10. Expression Data from Allogeneic Human Mesenchymal Stem Cells and Primary Cultures of Human Alveolar Epithelial Type II Cells OmicsDI

    ID: E-GEOD-68610

    Date Released: 08-19-2015

    Description: Acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) is a severe syndrome affecting more than 200,000 patients annually in the U.S. ...

  11. Comparative transcriptomic analysis of self-organized, in vitro generated optic tissues OmicsDI

    ID: E-GEOD-62432

    Date Released: 08-19-2015

    Description: Embryonic stem (ES) cells have a remarkable capacity to self-organize complex, multi-layered optic cups in vitro via a culture technique called SFEBq....

  12. Characterizing the molecular spatial and temporal field of injury in early stage smoker non-small cell lung cancer patients after definitive surgery b... OmicsDI

    ID: E-GEOD-40407

    Date Released: 08-19-2015

    Description: Gene expression alterations in response to cigarette smoke have been characterized in normal-appearing bronchial epithelium of healthy smokers and it ...

  13. DNA methylation data from cell lines originating from patients with multiple myeloma OmicsDI

    ID: E-GEOD-68259

    Date Released: 08-19-2015

    Description: We performed genome-wide DNA methylation profiling of KMS11, MM.1S, and RPMI8226 multiple myeloma cell lines to identify methylation changes distinct ...

  14. Identification of novel, highly expressed retroviral microRNAs in cells infected by bovine foamy virus OmicsDI

    ID: E-GEOD-67620

    Date Released: 08-19-2015

    Description: While numerous viral microRNAs (miRNAs) expressed by DNA viruses, especially herpesvirus family members, have been reported, there have been very few ...

  15. DNA methylation data from 11 normal and 9 chronic periodontitis patients from site USC OmicsDI

    ID: E-GEOD-59939

    Date Released: 08-19-2015

    Description: Microarray methylation (Infinium®HumanMethylation 450 BeadChip from Illumina) was performed on 11 normal and 9 chronic periodontitis (CP) patients Bi...

  16. Transcription profiling by array of Drosophila larvae infected with parasitoid wasps OmicsDI

    ID: E-GEOD-8938

    Date Released: 04-30-2015

    Description: Although host-parasitoid interactions are becoming well characterized at the organismal and cellular levels, much remains to be understood of the mole...

  17. Transcription profiling by array of human CD4+ and CD8+ T cells from HUV patients OmicsDI

    ID: E-GEOD-6740

    Date Released: 04-30-2015

    Description: We examined the gene expression profiles in ex vivo human CD4+ and CD8+ T cells from untreated HIV-infected individuals at different clinical stages a...

  18. Transcription profiling by array of skeletal muscles of flies with muscle-specific overexpression of Foxo or Mnt OmicsDI

    ID: E-GEOD-39877

    Date Released: 04-30-2015

    Description: Skeletal muscle senescence influences whole organism aging, yet little is known on the relay of pro-longevity signals from muscles to other tissues. W...

  19. Transcription profiling of mouse embryonic day 13.5 and 15.5 fetal livers lacking p38alpha, a mitogen-activated kinase that controls inflammatory resp... OmicsDI

    ID: E-GEOD-7342

    Date Released: 04-30-2015

    Description: The mitogen-activated protein kinase (MAPK) p38alpha controls inflammatory responses and cell proliferation. Using mice carrying conditional p38alpha ...

  20. Transcription profiling by array of Arabidopsis mutant for phr1 and phl1 or phr1 only after phosphate deprivation OmicsDI

    ID: E-GEOD-16722

    Date Released: 04-29-2015

    Description: We performed a transcriptomic analysis of Pi starvation responses in Arabidopsis thaliana (Columbia-0) wild type plants under phosphate starvation str...

  21. Transcription profiling by array of Arabidopsis mutant for rts1 OmicsDI

    ID: E-GEOD-18988

    Date Released: 04-30-2015

    Description: In addition to the canonical RNAi pathways that targets mRNAs in the cytoplasm, several RNA-dependent pathways operate in the nucleus to induce sequen...

  22. Transcription profiling by array of Arabidopsis mutant for sid2 or tga2, tga3, tga5 and tga6 after treatment with mefenpyr and isoxadifen OmicsDI

    ID: E-GEOD-25489

    Date Released: 04-30-2015

    Description: Comparison of gene expression changes in safener- or BF-treated wild type (Col0) or mutants (tga2tga3tga5tga6, sid2-2) of the salicylic acid signaling...

  23. Calorie/Dietary Restriction and Resveratrol in Female Drosophila Melanogaster Head/Thorax OmicsDI

    ID: E-GEOD-26724

    Date Released: 04-30-2015

    Description: Feeding resveratrol to Drosophila melanogaster extends lifespan. Studies of microarray show similarities between calorie/dietary restriction and resve...

  24. Transcription profiling by array of mouse heart mutant for Ezh2 OmicsDI

    ID: E-GEOD-30076

    Date Released: 04-30-2015

    Description: Adult-onset diseases can be associated with in utero events, but mechanisms for such temporally distant dysregulation of organ function remain unknown...

  25. Transcription profiling by array of U937 cells transduced with retroviral vectors encoding REtr or c-KIT(N822K) OmicsDI

    ID: E-GEOD-57658

    Date Released: 04-30-2015

    Description: REtr causes genomic instability in U937 cells. Activated forms of c-KIT, like c-KIT(N822K), rescues the Retr induced genomic instability by increasing...

  26. Transcription profiling by array of human lymphoblast cells from a patient with Freidriech's ataxia after treatment with pyrrole-imidazole polyamides OmicsDI

    ID: E-GEOD-5040

    Date Released: 04-30-2015

    Description: Lymphoblast cells from a patient with Freidriech's Ataxia were incubated with pyrrole-imidazole polyamides targeted to the GAA triplet repeat in the i...

  27. Genetic variants regulating ORMDL3 expression are determinants of susceptibility to childhood asthma OmicsDI

    ID: E-GEOD-8052

    Date Released: 04-30-2015

    Description: Asthma is caused by a combination of poorly understood genetic and environmental factors. We found multiple markers on chromosome 17q21 to be strongly...

  28. Gene expression and epigenetic sexual dimorphism in two jewel wasp species Nasonia vitripennis and Nasonia giraulti [Bisulfite-Seq] OmicsDI

    ID: E-GEOD-61158

    Date Released: 06-13-2015

    Description: The extraordinary range in the degree of sexual dimorphism (SD) among animal species is widely perceived to be caused in part by differences in patter...

  29. Cerebellum Illumina Inf 450 DNA methylation samples from HIV+ and HIV- human subjects OmicsDI

    ID: E-GEOD-67748

    Date Released: 06-13-2015

    Description: Genome wide DNA methylation profiles of cerebellum from HIV positive and HIV negative human subjects. The Illumina Infinium 450k Human DNA methylation...

  30. Gene expression changes in control- and shSamd14-infected R1 fetal liver OmicsDI

    ID: E-GEOD-68602

    Date Released: 06-12-2015

    Description: Samd14 was discovered as a novel GATA-2 target gene. Samd14 increased hematopoietic progenitor levels/activity, promoted signaling by a pathway instr...

  31. Olfactomedin 4 serves as a marker for disease severity in pediatric Respiratory Syncytial Virus (RSV) infection OmicsDI

    ID: E-GEOD-69606

    Date Released: 06-13-2015

    Description: Respiratory viral infections follow an unpredictable clinical course in young children ranging from a common cold to respiratory failure. The transiti...

  32. DNA methylation levels of various brain regions from HIV+ and HIV- subjects OmicsDI

    ID: E-GEOD-59457

    Date Released: 06-13-2015

    Description: Genome wide DNA methylation profiles of various human brain regions (cerebellum, occipital lobe, etc). The Illumina Infinium 450k Human DNA methylatio...

  33. Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood OmicsDI

    ID: E-GEOD-69636

    Date Released: 06-13-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  34. Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [ChIP-Seq 2] OmicsDI

    ID: E-GEOD-38789

    Date Released: 06-12-2015

    Description: Basal-like and luminal breast tumors have distinct clinical behavior and molecular profiles, yet the underlying mechanisms are poorly defined. To inte...

  35. Gene expression profile in the liver of BALB/c mice infected with Fasciola hepatica OmicsDI

    ID: E-GEOD-69588

    Date Released: 06-13-2015

    Description: Background: Fasciola hepatica infection still remains one of the helminthic neglected tropical diseases (NTDs). It has a huge worldwide distribution, ...

  36. Transcriptomic comparison of chlorhexidine tolerant and sensitive Salmonella Typhimurium OmicsDI

    ID: E-GEOD-59566

    Date Released: 06-13-2015

    Description: Transcriptional profiles of a chlorhexidine tolerant Salmonella Typhimurium were compared to its, chlorhexidine sensitive, isogenic progenitor isolate...

  37. Regulatory RNA Apela Is a Component of a Negative Feedback Loop Regulating p53-Mediated Apoptosis in Embryonic Stem Cells (I) OmicsDI

    ID: E-GEOD-54355

    Date Released: 06-13-2015

    Description: p53-repressed transcripts have recently been shown to play important roles in various biological processes, such as stem cell differentiation and canc...

  38. Ileal gene expression in Duoxa-/- mice and cohoused littermate controls OmicsDI

    ID: E-GEOD-60933

    Date Released: 06-12-2015

    Description: Dual oxidases play a role in innate host defense at barrier epithelia. We examined the effect of loss of dual oxidase function (duoxa-/-) on gene expr...

  39. Microarray analysis of HK-2 cells treated with cisplatin OmicsDI

    ID: E-GEOD-69644

    Date Released: 06-13-2015

    Description: Chemotherapeutic use of cisplatin is limited by its severe side effects. In this study, we demonstrated that cisplatin induces cell death in a proxima...

  40. Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [SNP] OmicsDI

    ID: E-GEOD-39412

    Date Released: 06-12-2015

    Description: Basal-like and luminal breast tumors have distinct clinical behavior and molecular profiles, yet the underlying mechanisms are poorly defined. To inte...

  41. Transcription profiling of skeletal muscle in AMPK gamma3 mutant (R225Q) transgenic mice and wild type littermates OmicsDI

    ID: E-GEOD-4065

    Date Released: 04-30-2015

    Description: Analysis of AMPK gamma3-dependent transcriptional responses by analyzing global gene expression in the white portion of the gastrocnemius muscle in AM...

  42. Transcription profiling by array of Arabidopsis mutant for frb1 OmicsDI

    ID: E-GEOD-31033

    Date Released: 04-30-2015

    Description: Cell adhesion in plants is mediated predominantly by pectins, a group of complex cell wall associated polysaccharides. An Arabidopsis mutant, friable1...

  43. Transcription profiling by array of four distinct tissues of Arabidopsis root and whole root treated with (auxin) indole-3-acetic acid against mock-tr... OmicsDI

    ID: E-GEOD-35580

    Date Released: 04-30-2015

    Description: We performed an analysis of transcriptomic responses to auxin within four distinct tissues of the Arabidopsis thaliana root. This high-resolution data...

  44. Transcription profiling by array of Arabidopsis cdkf;1-2 mutant OmicsDI

    ID: E-GEOD-27687

    Date Released: 04-30-2015

    Description: Serine phosphorylation of conserved Y1S2P3T4S5P6S7 repeats of RNA polymerase II carboxy-terminal domain (RNAPII CTD) plays a central role in the regul...

  45. Transcription profiling by array of ovarian carcinoma TOV-112D cells treated with NSC319726 to investigate the effect on p53 targets OmicsDI

    ID: E-GEOD-35972

    Date Released: 04-30-2015

    Description: Rescuing the function of mutant p53 protein is an attractive cancer therapeutic strategy. Using the NCI anticancer drug screen data, we identified two...

  46. Transcription profiling by array of Drosophila Kc167 cells with RNAi knockdown of Enigma, a mitochondrial protein with homology to acyl-CoA dehydrogen... OmicsDI

    ID: E-GEOD-3566

    Date Released: 04-30-2015

    Description: 5 day RNAi treatment to knockdown Enigma, CG9006, a Drosophila mitochondrial protein with homology to acyl-CoA dehydrogenases. Experiment Overall Desi...

  47. The hypoxia-inducible transcription factor ZNF395 is controlled by I-kappaB kinase and activates genes involved in the innate immune response and canc... OmicsDI

    ID: E-GEOD-44327

    Date Released: 04-30-2015

    Description: Activation of the hypoxia inducible transcription factor HIF-alpha and the NF-kappaB pathway promotes inflammation mediated tumor progression. The cel...

  48. Transcription profiling by array of human breast cancer cell lines treated with fulvestrant OmicsDI

    ID: E-GEOD-22533

    Date Released: 04-30-2015

    Description: A significant fraction of breast cancers exhibit de novo or acquired resistance to estrogen deprivation. To model resistance to aromatase inhibitor (A...

  49. Structural evidence for Scc4-dependent localization of cohesin loading OmicsDI

    ID: E-GEOD-68573

    Date Released: 06-13-2015

    Description: Purpose: The Goal of this study is to look at 1) Differences in genome wide localization of Scc2 between wild type and scc4-m35 cells in S-phase 2) Di...

  50. Interference with ethylene perception at receptor level sheds light on auxin and transcriptional circuits associated with climacteric ripening of appl... OmicsDI

    ID: E-GEOD-78745

    Date Released: 09-12-2016

    Description: Apple (Malus x domestica Borkh.) is a model fruit species to study the metabolic changes occurring at the onset of ripening as well the physiological ...

  51. Study the function of miR-195 and miR-30d in prostate cancer cell (LNCap and DU145) OmicsDI

    ID: E-GEOD-85884

    Date Released: 09-12-2016

    Description: miRNAs are related with the initiation and development of prostate cancer. We discover the miR-195 and miR-30 can be as a biomarker of prognosis of pr...

  52. Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 OmicsDI

    ID: E-GEOD-75515

    Date Released: 09-12-2016

    Description: The aim of this study is to analyze the change in genome wide expression levels in HAP1 cells upon loss of SMARCB1, SMARCA4 or both these genes togeth...

  53. The RNA binding protein SYNCRIP is a component of the hepatocyte exosomal machinery controlling microRNAs sorting OmicsDI

    ID: E-MTAB-4502

    Date Released: 09-21-2016

    Description: Despite clear evidence that exosomal microRNAs (miRNAs) are able to modulate the cellular microenvironment and that exosomal RNA cargo selection is of...

  54. Transcription profiling by high throughput sequencing of Arabidopsis rbm25-1 mutant seedlings before and after abscisic acid treatment OmicsDI

    ID: E-GEOD-66737

    Date Released: 09-19-2016

    Description: We used RNA-seq platform to determine role of a splicing factor RBM25 in regulation of gene expression and pre-mRNA splicing. We found that a loss-of...

  55. Identification of expresion patterns after treatment with GC/RA and combination with AZA/SAHA in MYC amplified and BRG1 mutant lung cancer cell lines OmicsDI

    ID: E-GEOD-66244

    Date Released: 09-12-2016

    Description: To development our gene expression approach , we have employed whole genome microarray expression profiling as a discovery platform to identify genes ...

  56. Transcriptome Sequencing and Assembly of Canna indica Flower OmicsDI

    ID: E-GEOD-72440

    Date Released: 09-12-2016

    Description: Canna indica L. is an ornamental plant with petaloid staminodes and only a half fertile stamen in its flowers. The genetic basis for petaloid androeci...

  57. Active Demethylation of Both Maternal and Paternal Genomes in Mouse Zygotes OmicsDI

    ID: E-GEOD-60777

    Date Released: 09-12-2016

    Description: The epigenomes of mammalian sperm and oocytes, characterized by gamete-specific 5-methylcytosine (5mC) patterns, are reprogrammed in early embryogenes...

  58. Genome-wide OxyR and SoxRS transcriptional regulatory networks coordinate complex cellular responses to oxidative stress [ChIP-seq] OmicsDI

    ID: E-GEOD-65710

    Date Released: 08-19-2015

    Description: Oxidative stress that originates from reactive oxygen species (ROS) is an inevitable consequence of aerobic respiration in bacteria. Three transcripti...

  59. Widespread association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth [gene expression] OmicsDI

    ID: E-GEOD-66082

    Date Released: 08-19-2015

    Description: The goal of this study was to identify YAP/TAZ direct transcriptional targets and transcriptional partners, through ChIP-sequencing and gene expressio...

  60. Differences in the transcriptomic response of human adult and neonatal dendritic cell subsets to TLR7/8 stimulation OmicsDI

    ID: E-GEOD-67057

    Date Released: 08-19-2015

    Description: Previous studies have shown that purified dendritic cells (DCs) have cell-intrinsic, age-dependent differences in their response to TLR stimulation. T...

  61. Histone architecture of stem-cell memory T cells reveals progressive remodeling of epigenetic landscape in antigen-experienced CD8 T cells OmicsDI

    ID: E-GEOD-67881

    Date Released: 08-19-2015

    Description: We investigated the genomic landscape of histone modifications in antigen-experienced CD8+ T cells. Using a ChIP-Seq approach coupled with global gene...

  62. P. falciparum Complicated Malaria: Modulation and Connectivity between Exportome and Variant Surface Gene Families OmicsDI

    ID: E-GEOD-59844

    Date Released: 08-19-2015

    Description: In temperate and sub-tropical regions of Latin America, complicated malaria manifested as hepatic dysfunction or renal dysfunction is seen in all age ...

  63. Transcriptome analysis of 6 hours post fertilization mecp2-null versus wild type zebrafish embryos OmicsDI

    ID: E-GEOD-80348

    Date Released: 09-12-2016

    Description: RNA sequencing was performed on RNA isolated from groups of 6 hpf wild type and mecp2-null embryos (n=3 biological replicates per condition with 30 em...

  64. CXCL12/CXCR4 signaling mediates niche occupancy and tumor maintenance in T-cell leukemia OmicsDI

    ID: E-GEOD-60367

    Date Released: 08-19-2015

    Description: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy characterized by infiltration of the bone marrow and other sites...

  65. Influence of Autoinducer-2 (AI-2) in Salmonella Typhimurium Gene Expression OmicsDI

    ID: E-GEOD-23588

    Date Released: 08-19-2015

    Description: Salmonella enterica serovar Typhimurium is known to synthesize and respond to the cell signaling molecule, autoinducer-2 (AI-2). The luxS gene is invo...

  66. Transcriptional analysis between Streptomyces clavuligerus ATCC 27064 and a mutant altered in antibiotic production OmicsDI

    ID: E-GEOD-66683

    Date Released: 08-19-2015

    Description: The objective was to analyze the differential expression between the wild strain and the Streptomyces clavuligerus ΔclaR::aac mutant Six experimenta...

  67. miRNA expression in myeloid-derived suppressor cells (MDSCs) treated with or without whole β-glucan particles (WGP) OmicsDI

    ID: E-GEOD-67578

    Date Released: 08-19-2015

    Description: Murine MDSCs isolated from the spleens of Lewis lung carcinoma mice were treated with or without WGP, and then miRNA array was used to analyze the dif...

  68. Gene expression profiling of enforced HOXA1 expression in melanoma cell line (SkMel30) OmicsDI

    ID: E-GEOD-40422

    Date Released: 08-19-2015

    Description: We recently reported an oncogenomics-guided screening approach designed to identify genetic drivers of early stage melanoma metastasis, and in this st...

  69. Genomic analyses of breast cancer cells: 17β-hydroxysteroid dehydrogenase type 1 induces transcriptional changes in estradiol-dependent and independe... OmicsDI

    ID: E-GEOD-77345

    Date Released: 09-14-2016

    Description: 17β-HSD1 expression modulates T47D transcript profile in in steroid-deprived medium. The enzyme specifically regulates apoptosis and cancer-related g...

  70. Memory-like CD8 T-cells sustain the immune response to chronic viral infections. OmicsDI

    ID: E-GEOD-83978

    Date Released: 09-12-2016

    Description: We have discovered a small subpopulation of virus-specific CD8 T-cells that sustains the T-cell response in chronic infections. These cells are defin...

  71. HER2 expression identifies dynamic functional states within circulating breast cancer cells OmicsDI

    ID: E-GEOD-75367

    Date Released: 09-12-2016

    Description: Circulating tumour cells in women with advanced oestrogen-receptor (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cance...

  72. Phenotype and RNA-Seq-Based Transcriptome Profiling of Staphylococcus aureus biofilms in response to Tea tree oil OmicsDI

    ID: E-GEOD-85787

    Date Released: 09-12-2016

    Description: RNA sequencing (RNA-Seq) was used in our study to elucidate the mechanism of Tea tree oil (TTO) as a potential antibacterial agent to evaluate differe...

  73. Transcription profiling by high throughput sequencing of seven tissues of Brassica oleracea OmicsDI

    ID: E-GEOD-42891

    Date Released: 09-19-2016

    Description: Deep sequencing of mRNA from seven different tissues of Brassica oleracea Analysis of ploy(A)+ RNA of multiple different tissues of Brassica oleracea ...

  74. Identification of TWIST1 transcriptional targets in the cranial mesoderm [E8_5] OmicsDI

    ID: E-GEOD-80334

    Date Released: 09-12-2016

    Description: TWIST1, a basic helix-loop-helix transcription factor is essential for the development of cranial mesoderm and cranial neural crest-derived craniofaci...

  75. Genome-wide identification of bZIP29 & bZIP69 target genes in Arabidopsis cell cultures OmicsDI

    ID: E-MTAB-3754

    Date Released: 09-25-2016

    Description: Two Arabidopsis basic leucine zipper TFs (bZIP29 and bZIP69) of the bZIP group I TF family, expressed mainly in proliferative tissues, are functionall...

  76. Aurora kinase inhibition triggers senescence in human melanoma cells OmicsDI

    ID: E-GEOD-50474

    Date Released: 09-12-2016

    Description: Phenotypically, there is a heterogeneous response of cancer cells to chemotherapy or targeted therapy. While therapeutically much attention is focused...

  77. BRACHYURY orchestrates distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells OmicsDI

    ID: E-GEOD-60606

    Date Released: 08-19-2015

    Description: The transcription factor BRACHYURY (T, BRA) is one of the first markers of gastrulation and lineage specification in mammals. Despite its wide use and...

  78. Different molecular pathways along with pathogenesis of three subtypes of Leiomyosarcoma OmicsDI

    ID: E-GEOD-54511

    Date Released: 08-19-2015

    Description: Leiomyosarcoma (LMS) is a malignant neoplasm of smooth muscle and is an aggressive soft tissue tumor, have complex genetic abnormalities and could be ...

  79. Gene expression analysis of hematological malignancies and healthy (non-)hematopoietic cell types OmicsDI

    ID: E-GEOD-76340

    Date Released: 09-12-2016

    Description: Cellular immunotherapy has proven to be effective in the treatment of hematological cancers by donor lymphocyte infusion after allogeneic hematopoieti...

  80. Genome-wide identification of Drought-responsive Regulatory Coding and Non-coding Transcripts from Oryza sativa L. by deep RNA sequencing OmicsDI

    ID: E-GEOD-74465

    Date Released: 09-12-2016

    Description: Abiotic environmental stresses cause serious economic losses in agriculture. These stresses include temperature extremes, high salinity and drought. T...

  81. ROSA26Foxf1; Tie2-cre lung gene expression analysis. OmicsDI

    ID: E-GEOD-77881

    Date Released: 09-14-2016

    Description: Analysis of genes deregulated due to heterozygous overexpression of Foxf1 in endothelial and hematopoietic cells using Tie2-cre in embryonic day 18.5 ...

  82. Cytokine-independent detection of antigen-specific germinal center T follicular helper (Tfh) cells in immunized non-human primates using a live cell A... OmicsDI

    ID: E-GEOD-81382

    Date Released: 09-12-2016

    Description: A range of current candidate AIDS vaccine regimens are focused on generating protective HIV neutralizing antibody responses. Many of these efforts rel...

  83. Impact of bariatric surgery on RNA-seq gene expression profiles of peripheral monocytes in humans OmicsDI

    ID: E-GEOD-66306

    Date Released: 08-19-2015

    Description: Genome-wide expression profiles in peripheral monocytes (PM) from 19 obese women before and 3 months after bariatric surgery using the RNA-seq technol...

  84. Expression data from prostate cancer and benign prostate glands OmicsDI

    ID: E-GEOD-46602

    Date Released: 08-19-2015

    Description: Prostate cancer is a leading cause of cancer death amongst males. The main clinical dilemma in treating prostate cancer is the high number of indolent...

  85. The forkhead transcription factor FOXP1 profile in B-cells and B-cell lymphoma cell lines OmicsDI

    ID: E-GEOD-69009

    Date Released: 08-19-2015

    Description: Expression of the forkhead transcription factor FOXP1 is essential for early B cell development, whereas downregulation of FOXP1 at the germinal cente...

  86. Analysis to evaluate the presence of 5’ cap in intragenic lncRNAs OmicsDI

    ID: E-GEOD-62984

    Date Released: 08-19-2015

    Description: RNA aliquots were digested with 5’-phosphate-dependent exonuclease (5'-exo) following pre-treatment with tobacco acid pyrophosphatase (TAP) to relea...

  87. Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development OmicsDI

    ID: E-GEOD-65818

    Date Released: 08-19-2015

    Description: Alternative splicing (AS) generates vast transcriptomic complexity in the vertebrate nervous system. However, the extent to which trans-acting splicin...

  88. Bulk RNA-seq analysis of Type 5 retinal bipolar cells from the Htr3a-GFP line OmicsDI

    ID: E-GEOD-81902

    Date Released: 09-12-2016

    Description: 15,000 GFP+ cells were collected from two replicates of the Htr3a GFP line into RNAlater (ThermoFisher, AM7024). RNA was purified and bulk RNA-seq was...

  89. Steinernema carpocapsae Breton small RNA sequencing insect in vitro simulation system, from "The genome, transcriptome, and proteome of the nemat... OmicsDI

    ID: E-GEOD-85256

    Date Released: 09-12-2016

    Description: We report small RNA sequencing of the entomopathogenic nematode Steinernema carpocapsae. The nematodes were grown in liquid culture in homogenates of ...

  90. Transcriptional profiling of PRDM2 Knock down vs.controlGFPsh proliferating C2C12 Myoblasts OmicsDI

    ID: E-GEOD-58675

    Date Released: 08-19-2015

    Description: Knockdown of PRDM2 led to precocious differentiation. To understand the molecular basis for this phenotype, we performed microaary analysis of growing...

  91. An epigenetic memory of pregnancy in the mouse mammary gland OmicsDI

    ID: E-GEOD-67386

    Date Released: 08-19-2015

    Description: Pregnancy is the major modulator of mammary gland activity. It induces a tremendous expansion of the mammary epithelium and the generation of alveolar...

  92. Conversion of MyoD to a neurogenic factor: binding site specificity determines lineage OmicsDI

    ID: E-GEOD-64627

    Date Released: 08-19-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  93. GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27. OmicsDI

    ID: E-GEOD-68957

    Date Released: 08-19-2015

    Description: GATA4 is expressed in the proximal 85% of small intestine where it promotes a proximal intestinal ('jejunal') identity while repressing a distal intes...

  94. Molecular analysis of precursor lesions in familial pancreatic cancer OmicsDI

    ID: E-GEOD-43288

    Date Released: 08-19-2015

    Description: Background: With less than a 5% survival rate pancreatic adenocarcinoma (PDAC) is almost uniformly lethal. In order to make a significant impact on su...

  95. Assessment of MEK-ERK pathway targeting by BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias OmicsDI

    ID: E-GEOD-66293

    Date Released: 08-19-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  96. Accurate prediction and validation of response to endocrine therapy in breast cancer OmicsDI

    ID: E-GEOD-59515

    Date Released: 08-19-2015

    Description: Purpose Aromatase inhibitors (AIs) have an established role in breast cancer treatment. Response rates are only 50-70% in the neoadjuvant setting and...

  97. Slit2/Robo axis is mandatory for neural remodeling in pancreatic cancer. OmicsDI

    ID: E-GEOD-50570

    Date Released: 08-19-2015

    Description: Pancreatic Ductal Adenocarcinoma (PDA) is a critical health issue in cancer field with little new therapeutic options. Several evidences support an im...

  98. Genome-wide chromatin-immunoprecipitation studies of purified SAN cells reveals critical direct targets of ISL1 and suggests potential co-factor famil... OmicsDI

    ID: E-GEOD-68974

    Date Released: 08-19-2015

    Description: Understanding factors that drive development and function of the sinoatrial node (SAN) is crucial to development of potential therapies for sinus arrh...

  99. IL-2-dependent gene expression by human regulatory T cells OmicsDI

    ID: E-GEOD-49817

    Date Released: 08-19-2015

    Description: This study determined the genes that are differetially expressed when regulatory T cells were stimulated in vitro with IL-2 388 Affymetrix targets wer...

  100. ICL010 - Infection of Calu-3 cells with H1N1 influenza virus A/Netherlands/602/2009 OmicsDI

    ID: E-GEOD-40844

    Date Released: 08-19-2015

    Description: Differential expression was determined in Calu-3 cells between mock infected and infected with H1N1 influenza virus A/Netherlands/602/2009 at nine tim...

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