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  1. HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins OmicsDI

    ID: E-GEOD-75839

    Date Released: 12-19-2015

    Description: LMO2 is a component of multisubunit DNA-binding transcription factor complexes that regulate gene expression in hematopoietic stem and progenitor cell...

  2. Trophoblast stem cells (TSC) global transcriptome in stemness and differentiation conditions after treatment with PF1-3 OmicsDI

    ID: E-GEOD-65358

    Date Released: 12-18-2015

    Description: Here we report a potent, acetyl-lysine competitive and cell active inhibitor, PFI-3, that tightly binds to the bromodomain present in BRG1/BRM and the...

  3. Expression data from maize stems attacked by European corn borer (ECB, Ostrinia nubilalis) larvae OmicsDI

    ID: E-GEOD-46475

    Date Released: 12-14-2015

    Description: ECB larvae remain damaging pests of conventiational maize production. To better understand the physiological and molecular changes occuring in stem ti...

  4. NSD3-short is an adaptor protein that couples BRD4 to the CHD8 chromatin remodeler OmicsDI

    ID: E-GEOD-71186

    Date Released: 12-18-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  5. Effect of YAP overexpression on HuCCT1 cholangiocarcinoma cell line transcriptome (YAP overexpression) OmicsDI

    ID: E-GEOD-61764

    Date Released: 12-13-2015

    Description: The YAP pathway in regulating organ size by integrating external signals to control the expression of genes involved in cell proliferation. YAP is kno...

  6. AKT Inhibition Promotes Non-autonomous Cancer Cell Survival [RNA-Seq] OmicsDI

    ID: E-GEOD-71900

    Date Released: 12-12-2015

    Description: Small-molecule inhibitors of AKT signaling are being in evaluated in patients with various cancer types, but have so far proven therapeutically disapp...

  7. Espression data of control and heat-stressed Arabidopsis WT, hd2c-3, brm-1 and brm-1 hd2c-3 plants OmicsDI

    ID: E-GEOD-75646

    Date Released: 12-13-2015

    Description: Studies in yeast and animals have revealed that histone deacetylases (HDACs) often act as components of multiprotein complexes, including chromatin re...

  8. Effects of BMPR2 Loss in Human Pulmonary Artery Endothelial Cells OmicsDI

    ID: E-GEOD-70456

    Date Released: 12-13-2015

    Description: Pulmonary arterial hypertension (PAH) is a fatal disease characterized by a proliferative endothelial cell phenotype, inflammation and pulmonary vascu...

  9. Endometrial gene expression in recurrent implantation failure after IVF OmicsDI

    ID: E-MTAB-2591

    Date Released: 12-12-2015

    Description: Patient-control group project investigating recurrent failure of embryo-implantation by expression analysis of endometrium biopsies

  10. Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays OmicsDI

    ID: E-GEOD-74792

    Date Released: 12-12-2015

    Description: Stem cell differentiation strategies and optimization for generating lineage-specific cells and tissues most frequently rely on a three-dimensional em...

  11. Genome-wide mapping of Mef2c-bound sites in early B-cell progenitors OmicsDI

    ID: E-GEOD-73453

    Date Released: 12-19-2015

    Description: The sequential activation of distinct developmental gene networks governs the ultimate identity of a cell, but the mechanisms by which downstream prog...

  12. RNA-sequencing analysis of 5' capped RNAs identifies novel differentially expressed genes in sessile serrated colon polyps (SSPs) OmicsDI

    ID: E-GEOD-46513

    Date Released: 12-18-2015

    Description: RNA-sequencing of SSP RNA from patients with serrated polyposis syndrome identifies VSIG1 and MUC17 as potential diagnostic markers for SSPs 5' capped...

  13. Genome-wide occupancy of Rif1FH in mouse ESC OmicsDI

    ID: E-MTAB-3502

    Date Released: 12-15-2015

    Description: Mammalian Rif1 defines the architecture of replication-timing domains interactions through the three-dimensional organization of the nuclear volume. D...

  14. Chromosome conformation capture in Rif1 null pMEFs OmicsDI

    ID: E-MTAB-3505

    Date Released: 12-15-2015

    Description: Mammalian Rif1 defines the architecture of replication-timing domains interactions through the three-dimensional organization of the nuclear volume.

  15. Saturating mutagenesis with assembled CRISPR-Cas9 ribonucleoprotein complexes. OmicsDI

    ID: E-MTAB-4143

    Date Released: 12-15-2015

    Description: The CRISPR-Cas9 system enables efficient sequence-specific mutagenesis for creating germline mutants of model organisms. Key constraints in vivo remai...

  16. SHEF1.3-derived retinal pigment epithelium for cell therapy is free of stem cell contaminants OmicsDI

    ID: E-MTAB-4154

    Date Released: 12-18-2015

    Description: Safety is the principle consideration with any clinical program, for which hESC and their derived products hold specific challenges. Differentiated c...

  17. Aedes aegypti Cry11Aa intoxication curve transcriptome OmicsDI

    ID: E-GEOD-74785

    Date Released: 12-19-2015

    Description: Transcriptomic analysis of mosquito larvae exposed to LC50 of Cry11Aa toxin from Bti at different times was conducted to determine defense response pa...

  18. IRF4, a master transcription factor, regulates genes involved in BCR signaling, antigen processing and presentation, and GC development OmicsDI

    ID: E-GEOD-64270

    Date Released: 12-19-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  19. Reconstruction of microRNA/genes transcriptional regulatory networks of multiple myeloma through in silico integrative genomics analysis OmicsDI

    ID: E-GEOD-70323

    Date Released: 12-19-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  20. IRF4, a master transcription factor, regulates genes involved in BCR signaling, antigen processing and presentation, and GC development [ChIP-chip] OmicsDI

    ID: E-GEOD-64268

    Date Released: 12-19-2015

    Description: Interferon regulatory factor 4 (IRF4) is a master transcription factor required for the maturation of germinal center B cells that eventually develop ...

  21. MLL-rearranged acute lymphoblastic leukemias upregulate BCL-2 through H3K79 methylation and are highly sensitive to the BCL-2 specific antagonist ABT-... OmicsDI

    ID: E-GEOD-74812

    Date Released: 12-18-2015

    Description: We present ChIP-seq in the t(4;11) cell line SEM for different components of the MLL-AF4 complex as well as other chromatin proteins Examination of 5 ...

  22. Gene expression analysis to identify Klf2 target genes in B-cell progenitors [Klf2_KO] OmicsDI

    ID: E-GEOD-73560

    Date Released: 12-19-2015

    Description: The sequential activation of distinct developmental gene networks governs the ultimate identity of a cell, but the mechanisms by which downstream prog...

  23. Spo11-oligo mapping in S. cerevisiae Ctf19/CCAN kinetochore sub-complex mutant mcm21 OmicsDI

    ID: E-GEOD-72683

    Date Released: 12-19-2015

    Description: During meiosis, crossover recombination is essential to link homologous chromosomes and drive faithful chromosome segregation. Crossover recombination...

  24. Expression data on human MO-to-DC and MO-to-MAC differentiation OmicsDI

    ID: E-GEOD-75938

    Date Released: 12-19-2015

    Description: Comparison of the RNA expression profiles of CD14+ monocytes from human peripheral blood with derived dendritic cells (DCs) and macrophages (MACs) obt...

  25. Identification of MEF2B, EBF1, and IL6R as chromosome bound targets of EBNA1 essential for EBV infected B-lymphocyte survival OmicsDI

    ID: E-GEOD-73887

    Date Released: 12-19-2015

    Description: EBNA1 is the EBV-encoded nuclear antigen required for viral episome maintenance during latency. EBNA1 is a sequence specific DNA binding protein with...

  26. The propagation of perturbations in shuffled bacterial gene networks OmicsDI

    ID: E-MTAB-3233

    Date Released: 12-17-2015

    Description: This dataset contains transcription profiles of TOP10 E.coli transformed with 85 rewired network plasmids first described in: Evolvability and hierar...

  27. Genome-wide ChIP-seq binding profiles and linked gene expression arrays [array] OmicsDI

    ID: E-GEOD-64068

    Date Released: 12-12-2015

    Description: Pu.1-mutated murine AML cell line X18.1.1 transfected with inducible Pu.1 (PuER) or empty vector (EV) and clonal lines selected. Cells were induced wi...

  28. Novel transcriptome signatures and markers defining murine macrophages at the extremes of the canonical M1 and M2 polarization spectrum OmicsDI

    ID: E-GEOD-69607

    Date Released: 12-12-2015

    Description: Classically (M1) and alternatively activated (M2) macrophages play distinct roles in various physiological and disease processes. Understanding the ge...

  29. Gene expression profiling of normal lung cells and K-RasG12V driven hyperplasias OmicsDI

    ID: E-GEOD-65256

    Date Released: 12-19-2015

    Description: We aimed to analyze the transcriptional profile of lung epithelial cells early after the expression of a resident K-RasG12V oncogene. This approach wa...

  30. Expression data of cDNA from the ACHN control and Kindlin-2-depleting cells OmicsDI

    ID: E-GEOD-76020

    Date Released: 12-19-2015

    Description: Kindlin-2, an integrin-interacting FERM-domain-containing protein, has been known to play critical roles for tumor progression. However, the role of K...

  31. Expression profiles of HepG2 cells treated with low-, high-dose of acetaminophen and solvent control OmicsDI

    ID: E-GEOD-53216

    Date Released: 12-19-2015

    Description: The transcriptomics changes induced in the human liver cell line HepG2 by low and high doses of acetaminophen and solvent controls after treatment for...

  32. NSD3-short is an adaptor protein that couples BRD4 to the CHD8 chromatin remodeler (ChIP-Seq) OmicsDI

    ID: E-GEOD-71183

    Date Released: 12-18-2015

    Description: The bromodomain and extraterminal (BET) protein BRD4 is a therapeutic target in acute myeloid leukemia (AML). Here, we demonstrate that the AML mainte...

  33. RIP-Chip analysis of the C. elegans FOG-1 and FOG-3 proteins OmicsDI

    ID: E-GEOD-73070

    Date Released: 12-19-2015

    Description: FOG-1/CPEB and FOG-3/Tob are the terminal regulators of the sex determination in C. elegans germ cells. CPEB and Tob proteins are both translational ...

  34. BMP signaling in mouse embryonic stem cells (ESCs) in the naïve and primed pluripotent states [RNA-Seq] OmicsDI

    ID: E-GEOD-70578

    Date Released: 12-12-2015

    Description: Carrying out both RNA-seq and Smad1/5 genome-wide chromatin immunoprecipitation and sequencing (ChIP-seq) analyses of mESCs in the naïve or primed st...

  35. RIP-seq of polyribosomal SLBP RNP OmicsDI

    ID: E-GEOD-62076

    Date Released: 12-19-2015

    Description: UV cross-linking and immunoprecipiatation with high throughput sequencing of cytoplasmic SLBP RNP Polyclonal α-SLBP antibody was used to immunoprecip...

  36. Molecular patterns of diffuse and nodular parathyroid hyperplasia in long-term hemodialysis OmicsDI

    ID: E-GEOD-75886

    Date Released: 12-27-2015

    Description: Secondary hyperparathyroidism is well known complication manifested in end-stage renal disease (ESRD). Both nodular and diffuse parathyreoid hyperplas...

  37. Cause and consequence of tethering a sub-TAD to different nuclear compartments OmicsDI

    ID: E-GEOD-76174

    Date Released: 12-27-2015

    Description: Detailed genomic contact maps have revealed that chromosomes are composed of developmentally stable topologically associated domains (TADs) and more ...

  38. ChIP-seq analysis of MBD3 in human breast cancer cells OmicsDI

    ID: E-GEOD-76116

    Date Released: 12-26-2015

    Description: Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a powerful approach to identify the genome-wide localization of ...

  39. Investigating pathogen defense mechanisms of porcine mammary epithelial cells in vitro. OmicsDI

    ID: E-GEOD-64246

    Date Released: 12-27-2015

    Description: Porcine mammary epithelial cell (PMEC) cultures of three lactating sows were treated with potential mastitis-causing pathogens E. coli and S. aureus i...

  40. Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs [Affymetrix] OmicsDI

    ID: E-GEOD-54058

    Date Released: 12-26-2015

    Description: Alu SINEs are the most numerous frequently occurring transcription units in our genome and possess sequence competence for transcription by RNA Pol II...

  41. Gene expression profiling of human neuroblastoma cell line BE(2)-C with inducible KDM4C expression OmicsDI

    ID: E-GEOD-65966

    Date Released: 12-27-2015

    Description: The microarray gene expression profiling reveals that the histone H3 demethylase KDM4C transcriptionally activates the serine-glycine pathway, stress ...

  42. Limiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner OmicsDI

    ID: E-GEOD-73942

    Date Released: 12-20-2015

    Description: Cellular lipid requirements are achieved through a combination of biosynthesis and import programs. Using isotope tracer analysis, we show that type I...

  43. A XEN-like state bridges somatic cells to pluripotency during chemical reprogramming OmicsDI

    ID: E-GEOD-73631

    Date Released: 12-20-2015

    Description: Pluripotent stem cells can be generated from somatic cells by using pure chemicals.However, the cell fate dynamics and molecular events that occur dur...

  44. Analysis of mRNA of leukocytes before and after exercise in 3 warmblood horses OmicsDI

    ID: E-GEOD-76310

    Date Released: 12-25-2015

    Description: Capacity of exercise and performance is the most valuable in the horses. They have been selected for strength, speed, and indurance trait. Athletic ph...

  45. Transcription profiling by array of yeast single and double deletion mutants of gene-specific transcription factors OmicsDI

    ID: E-GEOD-42536

    Date Released: 12-25-2015

    Description: Contains gene expression profiles of yeast single and double deletion mutants of gene-specific transcription factors. Genetic interactions were studie...

  46. The effects of CEP-37440, an inhibitor of focal adhesion kinase, in vitro and in vivo on inflammatory breast cancer cells. OmicsDI

    ID: E-GEOD-73285

    Date Released: 12-19-2015

    Description: CEP-37440 at low concentration (1,000 nM) decreased the proliferation of the human inflammatory breast cancer (IBC) cell line FC-IBC02, while not affe...

  47. The life history of retrocopies illuminates the evolution of new mammalian genes OmicsDI

    ID: E-GEOD-72236

    Date Released: 12-19-2015

    Description: New genes contribute substantially to adaptive evolutionary innovation, but the functional evolution of new mammalian genes has been little explored a...

  48. Somatosensory Neuron Types Identified by High-Coverage Single-Cell RNA-Sequencing and Functional Heterogeneity OmicsDI

    ID: E-GEOD-63576

    Date Released: 12-20-2015

    Description: Sensory neurons are distinguished by distinct signaling networks and receptive characteristics. Thus, sensory neuron types can be defined by linking t...

  49. Transcription profiling by array of antibody blockade of IL-17-family cytokines in immunity to acute murine oral mucosal candidiasis OmicsDI

    ID: E-MTAB-4167

    Date Released: 12-21-2015

    Description: IL17A KO mouse tongues after 2 days of C. albicans infection were profiled and compared to WT. In addition, tongues from animals infected for 2 days w...

  50. Acetylation of histone H4 at lysine 44 facilitates meiotic recombination by creating accessible chromatin OmicsDI

    ID: E-GEOD-59005

    Date Released: 12-20-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series


Displaying 50 of 78,272 results for " "