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  1. Analysis of the cell death inducing DFFA like effector c (Cidec)-dependent transciptome in mouse white adipose tissue NURSA

    Keywords: WAT unspecified

    Description: Gonadal WAT was removed from 3 month old male Cidec KO and WT mice.

    ID: 10.1621/vLRHR6z6zB

  2. Transcriptomic profiling of dexamethasone (Dex)-treated A549 cells NURSA

    Keywords: epithelium A549 cells

    Description: A549 lung epithelial carcinoma cells were treated with or without 100 nM Dex for 1 hour.

    ID: 10.1621/fWHdfBkOGh

  3. Analysis of the steroid receptor coactivator-1 (SRC-1/NCOA1)-regulated transcriptome in Tamoxifen (Tam)-treated LY2 cells NURSA

    Keywords:

    Description:

    ID: 10.1621/Wm28paxSgf

  4. Time course transcriptomic analysis of 17β-estradiol (17βE2)-treated MCF-7 cells NURSA

    Keywords: epithelium MCF-7 cells

    Description: Human MCF-7 breast cancer cells were treated for 6 h or 24 h with or without 1 nM 17βE2.

    ID: 10.1621/aZaho4wuZK

  5. Analysis of the 17β-estradiol (17βE2)-regulated transcriptome in mouse dorsal root ganglion NURSA

    Keywords: dorsal root ganglion T8-L4 cells

    Description: ~ 60 day old ovariectomized female Sprague Dawley rats were treated with and without 10 µg/kg body weight 17βE2 for 24 h and dorsal root ganglion ce...

    ID: 10.1621/taRqZZbWJh

  6. Time course comparative analysis of the 17α-ethinylestradiol (17αEE2)-regulated transcriptome in rat uterus NURSA

    Keywords: whole uterus

    Description: Immature ovariectomized female Sprague Dawley rats were treated with and without a single dose of 100 µg/kg body weight 17αEE2 and the uteri removed...

    ID: 10.1621/AEvCJpyNNb

  7. Analysis of the 17β-estradiol (17βE2)-regulated transcriptome in murine cerebral cortex NURSA

    Keywords: cerebrum cerebral cortex whole

    Description: Ovariectomized 15 week old C57BL/6J mice received a subcutaneous implant of 6.3 µg 17βE2 or vehicle. After 7 d mice were sacrificed and cerebral cor...

    ID: 10.1621/7yWxENU4Qh

  8. Chronic time course and dose-dependence analysis of the 17α-ethinylestradiol (17αEE2)-regulated transcriptome in rat kidney NURSA

    Keywords: whole kidney

    Description: Kidneys were isolated from rats treated for 4 - 29 d with or without 30 - 300 mg/kg bw/d 17αEE2.

    ID: 10.1621/BBRHpI4Ue5

  9. Time course transcriptomic analysis of R1881-treated LNCaP cells NURSA

    Keywords: epithelium LNCaP cells

    Description: Human LNCaP prostate cancer cells were treated with and without 10 nM R1881 for 6 h or 24 h.

    ID: 10.1621/uSlDnYWdEw

  10. Analysis of the 17β-estradiol (17βE2)-regulated, BRD4-dependent transcriptomes in MCF-7 breast cancer cells NURSA

    Keywords: epithelium MCF-7 cells

    Description: Parental or BRD4-depleted human MCF-7 breast cancer cells, pretreated with or without JQ1, a pan-bromodomain and extraterminal domain (BET) inhibitor,...

    ID: 10.1621/kw4nNzko44

  11. Analysis of the T0901317 (T1317) and AM580-regulated transcriptome in human monocyte-derived macrophages obtained from healthy donors NURSA

    Keywords: myeloid lineage macrophages monocyte-derived

    Description: Monocyte-derived macrophages obtained from 2 healthy human donors were treated for 24 h with 10 µM T1317 or vehicle followed by treatment for 24 h wi...

    ID: 10.1621/FU5dPEHCWO

  12. Analysis of the thyroid hormone (T3)-dependent transcriptome in mouse cerebral cortex NURSA

    Keywords: cerebrum cerebral cortex whole

    Description: Cerebral cortices were removed from control and hypothyroid mice at P21.

    ID: 10.1621/R6WUlFg7BK

  13. Transcriptomic profiling of medroxyprogesterone acetate (MPA)-treated human cultured myometrial explants NURSA

    Keywords: myometrium

    Description: Cultured myometrial explants were treated with and without 100 nM MPA for 65 h.

    ID: 10.1621/h2LxY5tkzD

  14. Comparative analysis of transcriptomes regulated by peroxisome proliferator activated receptor-α (PPARα/PPARA), PPARδ/PPARD or PPARγ/PPARG and the... NURSA

    Keywords: epithelium HepG2 cells

    Description: Human HepG2 HY-Toff cells, expressing members of the PPAR nuclear receptor subfamily (PPARα/PPARA, PPARδ/PPARD or PPARγ/PPARG) in the absence of te...

    ID: 10.1621/ZPnUZQAvgq

  15. Analysis of the pregnane X receptor (PXR/Nr1i2)-regulated, β-secretase-dependent transcriptome in mouse liver NURSA

    Keywords: whole liver

    Description: Liver was isolated from C57Bl/6 PXR/Nr1i2 knockout and wild-type mice treated for 96 h with vehicle or 150 mg/kg CMP013, a small molecule inhibitor of...

    ID: 10.1621/gvx9xVfhUI

  16. Analysis of the progesterone receptor (PR/PGR) B isoform-dependent transcriptome in R5020-treated human mammary epithelial cells NURSA

    Keywords:

    Description: Normal human mammary epithelial cells (hMECs) were infected with adenovirus containing the B isoform of PR/PGR (PR/PGR-B) or β-galactosidase then tre...

    ID: 10.1621/NGevvK3R1H

  17. Analysos of the androgen response element-independent and AR-independent transcriptomes in dihydrotestosterone (DHT)-treated LNCaP cells NURSA

    Keywords: epithelium LNCaP cells

    Description: Human LNCaP prostate cancer cells were treated with or without 1 nM DHT (DHT) for 16 h or, prior to DHT treatment, were pretreated: (1) for 48 h with ...

    ID: 10.1621/Y2NYDQA5ZI

  18. Dose-dependent analysis of the bisphenol A (BPA)-regulated transcriptome in MCF-10F cells NURSA

    Keywords: epithelium MCF-10F cells

    Description: Human MCF-10F immortalized breast epithelial cells were treated with 1 or 10 µM BPA or DMSO for 2 weeks.

    ID: 10.1621/PJiWshS2Kb

  19. Analysis of rosiglitazone (Rosi)-dependent transcriptomes in wild type or Stat6-depleted IL-4-treated murine bone-derived macrophages NURSA

    Keywords: myeloid lineage macrophages bone marrow-derived

    Description: Bone marrow derived macrophages from C57Bl/6 wild-type and Stat6 KO mice were treated with or without 1 µM Rosi and 20 ng/ml IL-4 for 10 days.

    ID: 10.1621/HA4DTjou1z

  20. Analysis of the SAM pointed domain containing ets transcription factor (SPDEF)-dependent transcriptome in MCF-7 breast cancer cells NURSA

    Keywords: epithelium MCF-7 cells

    Description: Human MCF-7 breast cancer cells were stably transfected with SPDEF shRNA expression vector or empty vector plasmid.

    ID: 10.1621/fQQMWsKduX

  21. Comparative analysis of estrogen receptor-α (ERα/ESR1)- and 17β-estradiol (17βE2)-regulated transcriptomes in MDA-MB-231 cells NURSA

    Keywords: epithelium MDA-MB-321 cells

    Description: Human MDA-MB-231 breast carcinoma cells were transduced for 24 h with recombinant adenovirus expressing ERα/ESR1 or LacZ in the presence or absence o...

    ID: 10.1621/8tdguE7Mvm

  22. Analysis of the 1,25-dihydroxyvitamin D3 (125DVD3)-dependent transcriptome in undifferentiated and differentiated MC3T3-E1 osteoblasts NURSA

    Keywords: osteoblasts MC3T3-E1 cells

    Description: Undifferentiated or differentiated MC3T3-E1 osteoblasts were treated with 100 nM 125DVD3 or vehicle for 24 h.

    ID: 10.1621/D9phTONsSL

  23. Genome-wide PPARγ binding in 3T3-L1 adipocytes NURSA

    Keywords: 3T3-L1 adipocytes

    Description: PPARγbinding regions in Day 10 3T3-L1 adipocytes obtained by ChIP-chip

    ID: 10.1621/datasets.05003

  24. Analysis of the hepatocyte nuclear factor 4-α (HNF4α/Hnf4a)-dependent transcriptome in mouse fetal colon NURSA

    Keywords: other mucosa whole mucosa

    Description: Colon was isolated from colon epithelial specific HNF4α/Hnf4a knockout mice and wild-type E18.5 mice.

    ID: 10.1621/OVl4sxIOj3

  25. Transcriptomic analysis of non-steroidal anti-inflammatory drug (NSAID) agonists of peroxisome proliferator activated receptor-γ (PPARγ/Pparg) in mo... NURSA

    Keywords: WAT adipocytes 3T3-L1-derived

    Description: Seven days postdifferentiation, mouse 3T3-L1 adipocytes were treated for 24 h with or without 100 nM rosiglitazone (Rosi) or the NSAIDs indomethacin (...

    ID: 10.1621/HdKr1ynHZH

  26. Analysis of the mediator complex subunit 1 (MED1)-dependent transcriptome in LNCaP prostate cancer cells NURSA

    Keywords: epithelium LNCaP cells

    Description: Human LNCaP prostate cancer cells were transiently transfected with mediator complex subunit 1 (MED1) or an empty vector control for 24 h.

    ID: 10.1621/IZpbXmHiKa

  27. Comparative analysis of the 17β-estradiol (17βE2), SAFB and SAFB2-regulated transcriptomes in MCF-7 cells NURSA

    Keywords: epithelium MCF-7 cells

    Description: Human MCF-7 breast cancer cells were transfected with either control non-targeting siRNAs or SAFB1 or SAFB2-targeting siRNAs for 48 h and treated with...

    ID: 10.1621/e2zmmx3zEg

  28. Time course analysis of the R1881-regulated transcriptome in the human LNCaP prostate cancer cell line NURSA

    Keywords: epithelium LNCaP cells

    Description: Human LNCaP prostate cancer cells were treated for 2 - 24 h with or without R1881.

    ID: 10.1621/43PVad2d8U

  29. Comparative analysis of the peroxisome proliferator activated receptor α (PPARα/Ppara)-regulated hepatic transcriptomine in the fasted and fed state... NURSA

    Keywords: whole liver

    Description: Liver was isolated from male Sv129 wild-type or PPARα/Ppara KO mice fasted or fed for 24 h.

    ID: 10.1621/nkQd3ECvlr

  30. Analysis of the IL6-regulated transcriptome in steroid receptor coactivator 1 (SRC-1/NCOA1)-depleted HepG2 cells NURSA

    Keywords: epithelium HepG2 cells

    Description: Human HepG2 liver hepatoma cells stably transfected with a SRC-1/NCOA1 shRNA lentivirus were treated with or without 10 ng/ml IL-6 for 1 h or 4 h.

    ID: 10.1621/aEblVNn86M

  31. Comparison of the dexamethasone (Dex) and AICAR-regulated hepatic transcriptomes in rat NURSA

    Keywords: whole liver

    Description: Liver was isolated from male Sprague-Dawley rats (180-200 g) treated with or without 1.5 mg/kg Dex for 8 h, 0.7 g/kg AICAR for 8 h, or both.

    ID: 10.1621/CRJSeDzawx

  32. Time course transcriptomic analysis of dexamethasone (Dex)-treated mouse chondroctyes NURSA

    Keywords: chondrocytes growth plate

    Description: Chondrocytes isolated from tibiae, femurs and humeri of E15.5 mouse embryos were treated with or without 100 nM Dex for 6 h or 24 h.

    ID: 10.1621/ZyPkWLa8Sl

  33. Analysis of the dexamethasone (Dex)-regulated transcriptome in HDAC6-depleted mouse liver NURSA

    Keywords: whole liver

    Description: Liver was isolated from C57BL/6 WT or histone deacetylase 6 (HDAC6) null mutant male mice treated with or without 1 mg/kg Dex for 3 wks.

    ID: 10.1621/oXEYR7YwcA

  34. Time course transcriptomic analysis of the phenobarbital (Phenb)-regulated transcriptome in mouse liver NURSA

    Keywords: whole liver

    Description: Liver was isolated from 6-8 week old male CD-1 mice treated with or without 850 ppm Phenob in the feed for 4 days or 30 days. This resulted in an aver...

    ID: 10.1621/1lIAjWjBMh

  35. Analysis of the progesterone receptor (PR/PGR)-dependent transcriptome in mose mammary gland NURSA

    Keywords: other whole mammary gland

    Description: Mammary glands were isolated from ovariectomized 10 week old PR/PGR knockout and wild-type BALB/c mice primed with 100 ng 17βE2 for 24 h and then tre...

    ID: 10.1621/rRuizMO74D

  36. Analysis of the dexamethasone (Dex) dependent transcriptome in imortalized human lens epithelial cells NURSA

    Keywords: eye lens epithelium HLE B-3 cells

    Description: Human HLE B-3 lens epithelial cells were treated with 1 µM Dex or vehicle for 4-16 h.

    ID: 10.1621/Oulg4ukCdS

  37. Analysis of the 17β-estradiol (17βE2)- and Tamoxifen (Tam)-regulated, estrogen receptor-β (ERβ/ESR2)-dependent transcriptomes in MCF-7 breast canc... NURSA

    Keywords: epithelium MCF-7 cells

    Description: Human MCF-7 breast cancer cells were transfected with an adenovirus expressing ERβ/ESR2 at a MOI of 50 for 48 h and then treated for 24 h with 10 nM ...

    ID: 10.1621/GyAJrdJZ5v

  38. Analysis of the dexamethasone (Dex)-regulated, hairy and enhancer of split-1 (HES1)-dependent transcriptome in human U2OS osteoblasts stably expressin... NURSA

    Keywords: osteoblasts U2OS-GR cells

    Description: Parental U2OS-GR cells and U2OS-GR cells overxpressing HES1 were treated with 100 nM Dex or vehicle for 6 h.

    ID: 10.1621/6DavcmUeVX

  39. Comparative transcriptomic analysis of isocaloric high fat diets (HFD) in murine liver NURSA

    Keywords: whole liver

    Description: Livers were isolated from mice fed for 35 weeks with a basic HFD (36 kcal% coconut oil; 4 kcal% soybean oil), a high soybean oil diet (SO-HFD; 21 kcal...

    ID: 10.1621/jd8E5LCa9m

  40. Analysis of the GW4064-regulated transcriptome in germline and liver-specific FXRα/Nr1h4 knockout mice NURSA

    Keywords: whole liver

    Description: C57BL/6 male mice 10-16 weeks of age were treated with or without two doses of 150 mg/kg GW4064 over a 24 h period. 2 h after the final dose, liver wa...

    ID: 10.1621/Nnt0Y1oFS1

  41. Analysis of the obese transcriptomic signature in human subcutaneous and omental white adipose tissue (WAT) NURSA

    Keywords: WAT subcutaneous

    Description: Subcutaneous and visceral WAT was obtained from morbidly obese insulin resistant and insulin sensitive patients udergoing gastric bypass surgery.

    ID: 10.1621/jz7WqnyYkE

  42. Analysis of the Alzheimer's disease transcriptomic signature in human frontal cortex, temporal cortex and hippocampus NURSA

    Keywords: cerebrum cerebral cortex frontal lobe

    Description: Gray matter of the (i) frontal cortex, (ii) temporal cortex and (iii) hippocampus was obtained from postmortem Alzheimer's disease and non-Alzheimer's...

    ID: 10.1621/cWqegmLiQi

  43. Analysis of the glucocorticoid receptor (GR/Nr3c1)-dependent, dexamethasone (Dex)-regulated transcriptome in mouse liver NURSA

    Keywords: whole liver

    Description: GR/NR3C1 knockout mice and wild-type mice were treated with Dex (200 µg/gram body weight) for 3 h before removal of livers

    ID: 10.1621/cpEvMuR8ZX

  44. Adipogenic expression patterns of nuclear receptors NURSA

    Keywords: 3T3-L1 preadipocytes C57Bl6J primary preadipocytes (S-V) adipocytes (Ad)

    Description: This dataset shows the effect of a cocktail of dexamethasone, 3-isobutyl-1-methylxanthine and insulin (DMI) and the PPAR-γ agonist rosiglitazone on n...

    ID: 10.1621/datasets.01006

  45. Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes NURSA

    Keywords: HeLa

    Description: This dataset is a HeLa cell affinity purification-based profile of interacting factors for nuclear receptor coactivators.

    ID: 10.1621/datasets.01001

  46. Quantitative mRNA Expression Profile of Nuclear Receptor Superfamily in HepG2 and HeLa Cells NURSA

    Keywords: HepG2 HeLa

    Description: In HepG2 and HeLa cells, we profiled mRNA expression of NR superfamily using TaqMan-based qRT-PCR assays

    ID: 10.1621/datasets.04011

  47. Analysis of the diethylstilbestrol (DES)-regulated transcriptome in mouse pituitary NURSA

    Keywords: pituitary prolactinoma

    Description: Ovary-intact female rats were implanted with subcutaneous Silastic tubing containing 5 mg DES for 70 days before the anterior pituitary was removed.

    ID: 10.1621/B9QlcNQzQh

  48. Analysis of the Tbl1xr1-regulated transcriptome in a mouse cell model of β-adrenoreceptor-stimulated lipolysis NURSA

    Keywords: WAT adipocytes 3T3-L1-derived

    Description: Differentiated 3T3-L1 adipoctyes were transduced for 3 d with adenovirus expressing Tbl1xr1 shRNA or control shRNA. Cells were subsequently treated fo...

    ID: 10.1621/d6F940WXdQ

  49. Time course transcriptomic analysis of adipogenic differentiation of human stromal vascular cells NURSA

    Keywords: WAT preadipocytes unspecified 1° cells

    Description: Human stromal vascular cells isolated from lipoaspirates of abdominal WAT were induced to differentiate into adipocytes with an adipogenic cocktail fo...

    ID: 10.1621/XJWcvyBLIt

  50. Analysis of the Tailless (TLX/NR2E1)-regulated transcriptome in human U2OS osteosarcoma cells NURSA

    Keywords: osteoblasts U2OS cells

    Description: Human U2OS osteosarcoma cells were transiently transfected for 24 h with human TLX/NR2E1 or empty vector control. Cells were subsequently treated for ...

    ID: 10.1621/c1yTx1QwUE


Displaying 50 of 931 results for " "