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  1. Cataloguing of Potential HIV Susceptibility Factors during the Menstrual Cycle of Pigtail Macaques OmicsDI

    ID: E-GEOD-68079

    Date Released: 08-19-2015

    Description: Our earlier studies in pig-tailed macaques demonstrated varying SHIV susceptibility during the menstrual cycle, likely caused by cyclic variations in ...

  2. dsRNA-seq of Physcomitrella patens rdr mutants OmicsDI

    ID: E-GEOD-51418

    Date Released: 08-19-2015

    Description: To investigate the effects of rdr2 and rdr6 mutations upon the strucutred component of the Physcomitrella patens transcriptome, dsRNAseq performed. Th...

  3. An antifungal benzimidazol reveals novel sterols after inhibition of Erg11. OmicsDI

    ID: E-GEOD-64976

    Date Released: 08-19-2015

    Description: Fungal infections are a serious health problem in clinics especially in the immune-compromised patient. Disease ranges from widespread superficial inf...

  4. RNA Proximity Ligation to Resolve Intramolecular RNA Structures in situ OmicsDI

    ID: E-GEOD-69472

    Date Released: 08-19-2015

    Description: Proof-of-concept of a new method involving the limited digestion and subsequent ligation of intramolecular RNA structures in situ followed by deep seq...

  5. Uppsala Longitudinal Study of Adult Men (ULSAM) OmicsDI

    ID: E-GEOD-48264

    Date Released: 08-19-2015

    Description: The Uppsala Longitudinal Study of Adult Men is a population-based study aimed at identifying risk factors for cardiovascular disease. At the time of b...

  6. Microarray Analysis Reveals a Role of the Notch System in Ciona Siphon Regeneration OmicsDI

    ID: E-GEOD-59280

    Date Released: 08-19-2015

    Description: Microarray analysis indicated many changes in gene expression, including genes related the the Notch signaling system, during oral siphon regeneration...

  7. Pichia angusta DL1 strain: Control vs. ER stress OmicsDI

    ID: E-GEOD-68528

    Date Released: 08-19-2015

    Description: Transcriptional profiling of ER stress condition comparing control (untreated), dithiothreitol (DTT) treated, or tunicamycin (TM) treated conditions o...

  8. Expression data from kidneys of rats with and without glomerulonephritis OmicsDI

    ID: E-GEOD-64265

    Date Released: 08-19-2015

    Description: We investigated a glomerulonephritis (GN) model in rats induced by nephrotoxic serum (NTS) which contains antibodies against the glomerular basement m...

  9. Tet1 is a tumor suppressor of hematopoietic malignancy OmicsDI

    ID: E-GEOD-65895

    Date Released: 08-19-2015

    Description: Epigenetic pathways that regulate DNA methylation and chromatin modifications are frequently found to be dysregulated in human cancers. The TET methyl...

  10. Whole Genome Bisulfite Sequencing (WGBS) of cKIT+ sorted cells from 57-137 day old fetal testes and ovaries. OmicsDI

    ID: E-GEOD-63393

    Date Released: 08-19-2015

    Description: We performed WGBS analyses on 6 human fetal samples at 53-137 days of development, 4 female and 2 male. We show that methylation reprogramming in the ...

  11. IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [miRNA-Seq] OmicsDI

    ID: E-GEOD-66808

    Date Released: 08-19-2015

    Description: IFN-g primes macrophages for enhanced inflammatory activation by TLRs and microbial killing, but little is known about the regulation of cell metaboli...

  12. An RNAi screen probing signaling control of human embryonic stem cells establishes the cell cycle-regulated restriction of the exit from pluripotency ... OmicsDI

    ID: E-GEOD-63215

    Date Released: 08-19-2015

    Description: Analysis of effect of Cyclin B1 overexpression on differentiating hESCs at the gene expression level. The hypothesis tested in the present study was t...

  13. Expression analysis of human PBMCs stimulated with Borrelia, MDP or Pam3cys. OmicsDI

    ID: E-GEOD-68765

    Date Released: 08-19-2015

    Description: Analysis examining the effect of the Crohn's disease-associated ATG16L1 polymorphism on the responses to stimulation components derived from various b...

  14. Alzheimer, MCI and control samples from AddneuroMed Cohort (batch 1) OmicsDI

    ID: E-GEOD-63060

    Date Released: 08-19-2015

    Description: Alzheimer case-control samples originate from the EU funded AddNeuroMed Cohort, which is a large cross-European AD biomarker study relying on human bl...

  15. Symmetrical dose-dependent DNA methylation profiles in children with deletion or duplication of chromosome 7q11.23 OmicsDI

    ID: E-GEOD-66552

    Date Released: 08-19-2015

    Description: Genome wide DNA methylation in blood derived DNA from individuals with deletion or duplication of 7q11.23 Bisulfite converted DNA was hybridized onto ...

  16. The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease OmicsDI

    ID: E-GEOD-66598

    Date Released: 01-03-2016

    Description: Alzheimer’s disease (AD) is a neurodegenerative disease characterized by a marked decline in cognition and memory formation. Increasing evidence hig...

  17. Lung miRNA profiling in mouse model of allergic airways disease OmicsDI

    ID: E-GEOD-72793

    Date Released: 01-03-2016

    Description: To determine the differential expression of miRNAs in the lungs of mice subjected to a model of allergic airways disease and non-allergic and steroid-...

  18. Human induced pluripotent stem cells derived from a sporadic Alzheimer's disease patient OmicsDI

    ID: E-GEOD-31163

    Date Released: 01-02-2016

    Description: Induced pluripotent stem cell (iPSC) disease models have been generated for a number of diseases, and some have shown their potential utilization for ...

  19. Identification of MEDIATOR16 as the Arabidopsis COBRA suppressor, MONGOOSE1   OmicsDI

    ID: E-GEOD-75199

    Date Released: 01-03-2016

    Description: RNAseq data for Col-0. cob-6, sfr6-3 and cob-6sfr6-3 7 days old seedlings grown in 24h light with 0

  20. Oct4 binding and Histone modification profiling during OSKM-mediated 2nd reprogramming OmicsDI

    ID: E-GEOD-67520

    Date Released: 01-03-2016

    Description: Forced expression of four transcription factors Oct4,Sox2, Klf4 and Myc (OSKM) induces somatic cell reprogramming towards pluripotency. Major efforts ...

  21. Streptococcus suis 05ZY: control vs contact with hBMEC 1 h OmicsDI

    ID: E-GEOD-46961

    Date Released: 01-02-2016

    Description: The interactions of Streptocococcus suis (S.suis) with human microvascular endothelial cells (hBMEC) are important process for S.suis passage across h...

  22. Expression data from OSKM-mediated 2nd reprogramming cells and the corresponding iPS cell line OmicsDI

    ID: E-GEOD-67462

    Date Released: 01-03-2016

    Description: Forced expression of four transcription factors Oct4,Sox2, Klf4 and Myc (OSKM) induces somatic cell reprogramming towards pluripotency. Major efforts ...

  23. Cryptochromes interact directly with PIFs to control plant growth in limiting blue light OmicsDI

    ID: E-GEOD-68193

    Date Released: 01-01-2016

    Description: Sun-loving plants have the ability to detect and avoid shading through sensing of both blue and red light wavelengths. Higher plant cryptochromes (CRY...

  24. BCOR controls maintenance of haematopoietic stem cell quiescence and regulates myeloid cell proliferation and differentiation [Illumina] OmicsDI

    ID: E-GEOD-69620

    Date Released: 01-01-2016

    Description: BCOR is a component of a variant Polycomb group repressive complex 1 (PRC1) complex. Recently, we and others reported recurrent somatic BCOR loss-of-f...

  25. Vascular niche induction of hematopoietic progenitors from pluripotent stem cells OmicsDI

    ID: E-GEOD-64644

    Date Released: 01-01-2016

    Description: Pluripotent stem cells (PSC) represent an alternative source of hematopoietic stem cells (HSCs). Clinical translation is impeded by limited engraftmen...

  26. Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (II) OmicsDI

    ID: E-GEOD-70613

    Date Released: 01-02-2016

    Description: In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for t...

  27. Mdm2 enhances stemness-promoting chromatin modifications through the Polycomb Repressor Complex 2 in a p53-Independent Manner [hMSC microarray] OmicsDI

    ID: E-GEOD-73601

    Date Released: 01-02-2016

    Description: The Mdm2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functions. Here we report that Mdm2 is required for the ...

  28. Models of Human Core Transcriptional Regulatory Circuitries OmicsDI

    ID: E-GEOD-76181

    Date Released: 12-27-2015

    Description: A small set of core transcription factors (TFs) dominates control of the gene expression program in embryonic stem cells and other well-studied cellul...

  29. G72 overexpression in U87 cells OmicsDI

    ID: E-GEOD-67704

    Date Released: 01-01-2016

    Description: G72 is a susceptible gene for schizophrenia. No matter genetic variation or serum levels, G72 has been recognized as a biomarker for schizophrenia. In...

  30. The effects of aging on circadian patterns of gene expression in the human prefrontal cortex OmicsDI

    ID: E-GEOD-71620

    Date Released: 01-02-2016

    Description: With aging, significant changes in circadian rhythms occur, including a shift in phase toward a “morning” chronotype and a loss of rhythmicity in ...

  31. ERK activation, gene dysregulations and cell transformation at submicromolar doses of Cr6+ in C3H10T1/2 and BALB/c 3T3 cells: interaction with Lipoic ... OmicsDI

    ID: E-GEOD-43156

    Date Released: 01-02-2016

    Description: The molecular mechanism of Cr6+ carcinogenicity is not well understood. Studies advocate a key involvement of the altered cytogenomics and dysregulate...

  32. The homeobox transcription factor Nkx2-1 regulates microRNAs controlling downstream gene silencing in lung epithelial cells (mRNA) OmicsDI

    ID: E-GEOD-47054

    Date Released: 12-26-2015

    Description: Cell-specific gene expression is achieved by a combination of mechanisms including transcriptional and post-transcriptional regulation. The transcript...

  33. Synergistic activity of BET protein antagonist-based combinations in Mantle Cell Lymphoma cells sensitive or resistant to ibrutinib OmicsDI

    ID: E-GEOD-70651

    Date Released: 01-02-2016

    Description: To determine the global transcriptome changes in mantle cell lymphoma cells following treatment with the BET bromodomain antagonist, JQ1 Mantle Cell L...

  34. Hormetic shifting of redox environment by the ROS-producing polyphenol resveratrol protects cells from oxidative stress OmicsDI

    ID: E-GEOD-72119

    Date Released: 01-02-2016

    Description: Resveratrol is a natural product that has gained tremendous interest due to multiple reported health-beneficial effects. However, the underlying mecha...

  35. CodeLink Mouse Whole Genome Bioarray data from hematopoietic stem cells (HSCs) of miR-125a (+/+) wild-type and miR-125a knockout mice with myeloprolif... OmicsDI

    ID: E-GEOD-69621

    Date Released: 01-01-2016

    Description: miR-125a knockout mice develop myeloproliferative disorder (MPD). To investigate the molecular mechanisms of MPD induced by the loss of miR-125a, gene...

  36. Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells OmicsDI

    ID: E-GEOD-66796

    Date Released: 12-26-2015

    Description: The human liver contains multiple cell types whose epigenetic patterns are undetermined. We examined the promoter methylome of purified and uncultured...

  37. Gene expression of 7 day combinatorial yohimbine and imipramine treated rat hippocampi OmicsDI

    ID: E-GEOD-61301

    Date Released: 01-03-2016

    Description: Rats treated on 7 consecutive days with either 2 injections of vehicle (Ctl) (DMSO for yohimbine, saline for imipramine) or Y+I (2mg/kg Yohimbine + 20...

  38. Cumulative low doses of the organic pesticide rotenone in the adult rat substantia nigra pars compacta OmicsDI

    ID: E-GEOD-22364

    Date Released: 01-02-2016

    Description: Adult male Sprague Dawley rats (5 month-old at the beginning of the study) were subcutaneously exposed to 0.5 rotenone or the corresponding so...

  39. Global Analysis of the Transcriptional Response of Chinese cabbage (Brassica rapa ssp. pekinensis) to Methyl Jasmonate Reveals JA Signaling on Enhance... OmicsDI

    ID: E-GEOD-51363

    Date Released: 01-03-2016

    Description: We conducted a RNA-Seq analysis of MeJA-treated Chinese cabbage leaf transcriptome. Total 14,619,469 sequence reads were generated to produce 27,461 d...

  40. Gene expression changes in Apc-mutant mouse intestinal organoids 7 and 20 days after the induction of the Apc deletion OmicsDI

    ID: E-GEOD-47569

    Date Released: 01-02-2016

    Description: We isolated and selected intestinal adenoma organoids from Lgr5-EGFP-IRES-CreER; Apcflox/flox mice and added tamoxifen to induce the deletion of the A...

  41. 5-Day Gavage Study of Propylene glycol phenyl ether (PPH; CASRN 770-35-4) in Male Harlan Sprague Dawley Rats OmicsDI

    ID: E-GEOD-75656

    Date Released: 01-02-2016

    Description: The goal of this study was to characterize the potential toxicity and genomic benchmark dose of propylene glycol phenyl etherl in liver and kidney of...

  42. Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (I) OmicsDI

    ID: E-GEOD-70611

    Date Released: 01-02-2016

    Description: In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for t...

  43. Genome-wide mapping of TEL-AML1 targets in acute leukemia OmicsDI

    ID: E-GEOD-67519

    Date Released: 01-03-2016

    Description: Around 20-25% of childhood acute lymphoblastic leukemias carry the TEL-AML1 (TA) fusion gene. It is a fusion of two central hematopoietic transcriptio...

  44. Transcription profiling by high throughput sequencing of Arabidopsis estradiol-inducible tor-es mutant OmicsDI

    ID: E-MTAB-4132

    Date Released: 01-04-2016

    Description: To validate that the transcriptional program rapidly activated by PP242, WYE354, KU63794 and Torin2 was specifically associated with the complete inhi...

  45. Relative spatial homogeneity revealed by transcriptional profiling of multi-region medulloblastoma samples OmicsDI

    ID: E-GEOD-62803

    Date Released: 01-03-2016

    Description: Affymetrix Human Gene 1.1 ST Array profiling of 52 primary, multi-region medulloblastoma samples. Total RNA was extracted from primary medulloblastoma...

  46. Pharmacodynamic effects of GLP-1 agonist liraglutide in adolescent, prediabetic pigs OmicsDI

    ID: E-GEOD-56427

    Date Released: 01-02-2016

    Description: GLP-1 agonists are potent glucose-lowering agents, however, their effect on adolescent organisms needs to be clarified Transgenic pigs expressing a do...

  47. Assessment of ability of hTSLP to maintain primary CRLF2 B-ALL cells in a xenograft model in a state more similar to the parent leukemia OmicsDI

    ID: E-GEOD-74339

    Date Released: 01-02-2016

    Description: Xenograft models represent an excellent method for expanding primary leukemias, but their ability to preserve the gene expression profile of the paren...

  48. Transcriptome analysis of annotated coding genes and sORF under elevated CO2 OmicsDI

    ID: E-GEOD-49960

    Date Released: 01-02-2016

    Description: There are seedling samples (high CO2 exposure of 0h, 2h, 6h, 12h, 1d, 3d, 7d, 14d) with duplicates in two chambers. Arabidopsis WT (Col-0) seeds were ...

  49. Small RNAs in stress-related rice cultivars OmicsDI

    ID: E-GEOD-64651

    Date Released: 01-01-2016

    Description: In this study, we sequenced small RNA content from three different rice cultivars employing Illumina technology. More than 15 million reads were gener...

  50. Gene expression data from SW1990 cells stably expressing Fbw7 OmicsDI

    ID: E-GEOD-76443

    Date Released: 01-01-2016

    Description: Fbw7 plays a negative role in pancreatic cancer tumorigenesis and progression. To further clarify the function and mechanism that Fbw7 plays in pancre...

Displaying 50 of 78,272 results for " "