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  1. Ubiquitin-dependent turnover of MYC promotes loading of the PAF complex on RNA Polymerase II to drive transcriptional elongation OmicsDI

    ID: E-GEOD-70009

    Date Released: 01-09-2016

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  2. Expression data from Saccharomyces cerevisiae OmicsDI

    ID: E-GEOD-49025

    Date Released: 01-09-2016

    Description: In this study, we characterize the protein uptake and degradation pathways of S. cerevisiae to better understand its impact on protein secretion titer...

  3. Adult mouse cortical cell taxonomy by single cell transcriptomics OmicsDI

    ID: E-GEOD-71585

    Date Released: 01-09-2016

    Description: Nervous systems are composed of numerous cell types, but the extent of cell type diversity is poorly understood. Here, we construct a cellular taxonom...

  4. GENE EXPRESSION ANALYSIS OF SYNOVIAL BIOPSIES AND PERIPHERAL BLOOD SAMPLES FROM PSORIATIC ARTHRITIS OmicsDI

    ID: E-MTAB-3201

    Date Released: 01-06-2016

    Description: Gene expression profiles of synovial biopsies and peripheral blood cells from Psoriatic Arthritis were compared to gene expression profiles of synovia...

  5. Effects of egg enrichment with glucocorticoid hormone, antagonist and receptor messenger in the modulation of gene expression in zebrafish (Danio reri... OmicsDI

    ID: E-GEOD-52398

    Date Released: 01-09-2016

    Description: Several studies have shown the presence of large reservoirs of maternally contributed liposoluble hormones in the yolk of mature teleost oocytes, such...

  6. MAGE-A1 Promotes Proliferation, Migration and Invasion of Human Melanoma Cells through RNA-SEQ Analysis via Affecting C-JUN-IL8-ARHGAP29 Network OmicsDI

    ID: E-GEOD-66859

    Date Released: 01-09-2016

    Description: To define the role of MAGE-A1 in melanoma growth and metastasis, we performed RNA-seq analysis on MAGE-A1 overexpression (OE) and knockdown (KD) model...

  7. Expression data from primary term human decidual cells treated with interleukin-1-beta for 6 hours. OmicsDI

    ID: E-GEOD-58220

    Date Released: 01-10-2016

    Description: Preterm birth is an important unsolved clinical problem. Despite advanced treatments, infants who survive prematurity remain at increased risk for pe...

  8. Transcription profiling by high throughput sequencing of maize third node in la1-ref mutant plants OmicsDI

    ID: E-MTAB-4196

    Date Released: 01-05-2016

    Description: The classical maize mutant lazy1 (la1), displayed prostrate growth with reduced shoot gravitropism. We compared the transcriptome profile of the third...

  9. Differentiation of human parthenogenetic pluripotent stem cells reveals multiple tissue and isoform specific imprinted transcripts OmicsDI

    ID: E-GEOD-65002

    Date Released: 01-10-2016

    Description: Parental imprinting results in a monoallelic parent-of-origin dependent gene expression. However, many imprinted genes identified by differential meth...

  10. SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 OmicsDI

    ID: E-GEOD-64642

    Date Released: 01-09-2016

    Description: We investigated the effect of SIRT6-knockout on gene expression and H3K4me3 modification profile in human mesenchymal stem cells. RNAs isolated from S...

  11. Sweet corn: low- vs. high-yielding hybrids OmicsDI

    ID: E-GEOD-73435

    Date Released: 01-09-2016

    Description: Transcriptional profiling of sweet corn plant density (crowding stress) tolerance influencing yield. Tolerance to crowding stress has played a crucial...

  12. Analysis of gene expression in human Bronchial Alveolar Lavage Cell (BAL) cell pellets OmicsDI

    ID: E-GEOD-74986

    Date Released: 01-08-2016

    Description: Clinical subphenotypes of asthma are characterized by pathological, cellular, and molecular heterogeneity of the airway. Gene expression profiling of ...

  13. transcription profiling by array of Arabidopsis pam48 (mterf6-1) mutants OmicsDI

    ID: E-GEOD-75824

    Date Released: 01-08-2016

    Description: Of the members of mitochondrial transcription termination factors (mTERFs) found in metazoans and plants known to regulate organellar gene expression ...

  14. Transcription profiling by high throughput sequencing of rice leaf sheaths and roots from plants grown under N-deficient or N-sufficient conditions fo... OmicsDI

    ID: E-MTAB-4195

    Date Released: 01-05-2016

    Description: Nitrogen (N), a critical macronutrient for plant growth and development, is a major limiting factor in most agricultural systems. Microarray analyses ...

  15. Gene expression characterization of high and low grade clear cell renal cell carcinoma OmicsDI

    ID: E-GEOD-68417

    Date Released: 01-09-2016

    Description: Patients undergoing either partial or radical nephrectomy at William Beaumont Hospital (Royal Oak, MI) were consented prior to surgery with local IRB ...

  16. Expression data from seedligs of wild type tomato seedlings (control) and InsP 5-ptase tansgenic line (L7) exposed to light stress OmicsDI

    ID: E-GEOD-58521

    Date Released: 06-21-2015

    Description: Objectives for this study included the identification of genes that were up or down-regulated at the transcriptional level in tomato InsP 5-ptase tran...

  17. Gene Expression Profiles of Chicken Embryo Fibroblasts in Response to Salmonella Enteritidis Infection OmicsDI

    ID: E-GEOD-67459

    Date Released: 06-21-2015

    Description: The response of chicken to non-typhoidal Salmonella infection is becoming well characterised but the role of particular cell types in this response is...

  18. Gene Expression Profiling Of Spinal Cord Injured Patients With Intractable Neuropathic Pain OmicsDI

    ID: E-GEOD-69901

    Date Released: 06-21-2015

    Description: Objective: Chronic pain is a major problem in patients with spinal cord injury (SCI). According to different studies, approximately 70% of patients wi...

  19. Distinctive responses of Mycobacterium smegmatis to exposure of low and high levels of hydrogen peroxide OmicsDI

    ID: E-MTAB-3594

    Date Released: 06-22-2015

    Description: Log phase cultures (OD600 of 0.8 - 1.0) of M. smegmatis mc2155 were diluted 1:100 into 7H9 media and cultured for approximately 12 hours until the OD6...

  20. Genome wide binding sites of NsrR in uropathogenic E.coli CFT073 OmicsDI

    ID: E-GEOD-69829

    Date Released: 06-21-2015

    Description: We applied ChIP-seq to identify genome wide binding targets of NsrR in E.coli CFT073. NsrR is a nitric oxide sensitive regulator of transcription. Ge...

  21. Global DNA methylation landscape reveals roles of DNA methylation involved in the regulation of drug metabolizing enzyme [II] OmicsDI

    ID: E-GEOD-67477

    Date Released: 06-21-2015

    Description: In order to elucidate the role of DNA methylation in the DME gene regulation, global DNA methylation and mRNA expression profiles of human tissues and...

  22. The effects of leptin deficiency on cold-induced energy expenditure OmicsDI

    ID: E-GEOD-59517

    Date Released: 06-21-2015

    Description: At 24 °C Lep-/- mice are hyperphagic compared to the Lep+/+ mice. Reducing the ambient temperature from 24 to 6 °C (3 °C per day) was accompanied b...

  23. Discrete Functions of Rev-erba Couple Metabolism to the Clock [array] OmicsDI

    ID: E-GEOD-67964

    Date Released: 06-21-2015

    Description: Circadian and metabolic physiology are intricately intertwined, as illustrated by Rev-erb , a transcription factor (TF) that functions both as a core ...

  24. Regional differences in left ventricular shear stress contribute to heterogenity of the endocardial transcriptome OmicsDI

    ID: E-MTAB-3669

    Date Released: 06-24-2015

    Description: The role of shear stress, the frictional force of blood flow, on the endothelium has been well documented. Differences in shear stress can have profou...

  25. Association of DNA Methylation with Acute Mania and Inflammatory Markers OmicsDI

    ID: E-GEOD-68777

    Date Released: 06-27-2015

    Description: Genome wide DNA methylation profiling of serum samples from 20 individuals hospitalized with acute mania and 20 unaffected controls using the Illumina...

  26. Tracking the elusive function of Bacillus subtilis Hfq OmicsDI

    ID: E-GEOD-66893

    Date Released: 06-27-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  27. Transcription profiling of human adult peripheral vs cord blood mononuclear cells altered by lipopolysaccharide to understand the influence of early m... OmicsDI

    ID: E-GEOD-3140

    Date Released: 06-22-2015

    Description: Neonatal gram-negative sepsis is often characterized by a fulminat clinical course compared to adults resulting in higher morbidity and mortality. Gen...

  28. Human brown and white preadipocyes clonal dynamics predict themorgenic potential and function OmicsDI

    ID: E-GEOD-68544

    Date Released: 06-21-2015

    Description: Brown adipose tissue (BAT) holds therapeutic potential for obesity and metabolic syndrome via increasing energy expenditure. Both inter- and intra-ind...

  29. MicroRNAs of the RPE are essential for RPE differentiation and photoreceptor maturation OmicsDI

    ID: E-GEOD-69883

    Date Released: 06-21-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  30. Expression data from CD4+ naïve T cells under Treg-inducing condition in the presence or absence of butyrate OmicsDI

    ID: E-GEOD-48045

    Date Released: 06-21-2015

    Description: Commensal bacteria shape the gut immune system. Colonization bacteria increase the frequency of regulatory T cells, however, the molecular mechanisms ...

  31. Mouse lung tissue transcriptome response to H1N1, H5N1, and mutants [mRNA] OmicsDI

    ID: E-GEOD-69945

    Date Released: 06-20-2015

    Description: The purpose is to obtain samples for mRNA, miRNA, proteomics, lipidomics, metabolomics, and histopathology analysis in mouse lung infected with WT A/V...

  32. Ecological transcriptomics: a non-lethal sampling approach for endangered fire salamanders OmicsDI

    ID: E-GEOD-70054

    Date Released: 06-27-2015

    Description: The analysis of transcriptomes is well-established and increasingly affordable in studies at the interface of ecology and evolution. Expression analys...

  33. ncRNA (non-coding RNA) signature in endothelial cells during hypoxia OmicsDI

    ID: E-GEOD-70034

    Date Released: 06-26-2015

    Description: To define ncRNA expression in hypoxic endothelial cells, we applied pro-angiogenic hypoxia to cultured endothelial cells. Afterwards total RNA was iso...

  34. Expression data from AsPC1 cells treated with ICG-001 OmicsDI

    ID: E-GEOD-57728

    Date Released: 06-22-2015

    Description: The CREB binding protein inhibitor ICG-001 suppresses pancreatic cancer growth We used microarrays to detail global gene expression changes in the pan...

  35. Comparative trascriptomic analysis between early-blastocyst and Hatched blastocyst OmicsDI

    ID: E-GEOD-38882

    Date Released: 06-27-2015

    Description: Comparative trascriptomic analysis between porcine early-blastocyst and Hatched blastocyst collected around day 5-6 direct comparison with dye-swap; t...

  36. Differences in gene expression profiles between human preimplantation embryos cultured in two different IVF culture media OmicsDI

    ID: E-MTAB-3405

    Date Released: 07-24-2015

    Description: Study question: Is gene expression in human preimplantation embryos affected by medium used for culturing embryos during an IVF treatment? Summary an...

  37. Mapping the Regulatory Network for Salmonella Typhimurium Invasion OmicsDI

    ID: E-MTAB-3765

    Date Released: 07-21-2015

    Description: Using RNAseq, the goal of the study is to investigate transcription factor regulation of virulence genes in 14028s Salmonella Typhimurium grown in SPI...

  38. Integrative analysis of histone ChIP-seq and gene expression microarray data using Bayesian mixture models OmicsDI

    ID: E-GEOD-49975

    Date Released: 07-21-2015

    Description: Histone modifications are a key epigenetic mechanism to activate or repress the expression of genes. Data sets of matched microarray expression data a...

  39. Transcriptional Atlas of Cardiogenesis Maps Congenital Heart Disease Interactome OmicsDI

    ID: E-GEOD-51483

    Date Released: 07-23-2015

    Description: Mammalian heart development is built on highly conserved molecular mechanisms with polygenetic perturbations resulting in a spectrum of congenital hea...

  40. Transcription profiling of human A549 pneumocyte cells infected with wild type and type III secretion system mutants of Pseudomonas aeruginosa OmicsDI

    ID: E-GEOD-1469

    Date Released: 07-24-2015

    Description: The bacterial type III secretion system (TTSS) is dedicated to directly effect host cell pathways by pathogens. In order to identify the key host resp...

  41. Exposure to Cobalt Causes Transcriptomic and Proteomic Changes in Two Rat Liver Derived Cell Lines OmicsDI

    ID: E-GEOD-51207

    Date Released: 07-22-2015

    Description: Cobalt is a transition group metal present in trace amounts in the human diet, but in larger doses it can be acutely toxic or cause adverse health eff...

  42. Menin-regulated genes in bone marrow B-cell progenitors OmicsDI

    ID: E-GEOD-49120

    Date Released: 07-16-2015

    Description: MLL1 translocations encode fusion proteins retaining the N-terminus of MLL1, which interacts with the tumor suppressor, menin. This interaction is ess...

  43. Gene expression profile of C1013G/CXCR4 mutated WM cells OmicsDI

    ID: E-GEOD-50683

    Date Released: 07-20-2015

    Description: C1013G/CXCR4 variant has been inserted into BCWM.1 cells, and gene expression profile has been performed on the mutated cells and on the parental cell...

  44. Transcription profiling by array of heart tissues from rats with different duration of triiodothyronine (T3)-induced hyperthyroidism and from normal c... OmicsDI

    ID: E-MTAB-2029

    Date Released: 07-13-2015

    Description: Although it is well known that the thyroid hormone (T3) is an important positive regulator of cardiac function over a short-term and that it also prom...

  45. Gene expression in human umbilical cord vein and artery endothelial cells under physiological chronic normoxia (3% O2, PCN) and standard culture normo... OmicsDI

    ID: E-GEOD-49958

    Date Released: 07-20-2015

    Description: Endothelial cells, and many other types of cells too, physiologically reside in low O2 environments (~ 2-13% O2 or 15-60 mmHg pO2; [PCN]) relevantly t...

  46. Porcine gene response following incision with energized devices OmicsDI

    ID: E-GEOD-47710

    Date Released: 07-15-2015

    Description: This study compares the gene expression changes in Sus scrofa in response to two different methods for abdominal surgical incisions ; electrosurgery a...

  47. Chip-seq analysis of changes in SUMO-2 binding to chromatin in response to heat shock in human U2OS cells OmicsDI

    ID: E-MTAB-2368

    Date Released: 07-13-2015

    Description: Analysis of changes in SUMO-2 binding to chromatin in response to heat shock in human U2OS cells

  48. Differential gene expression in the Lacrimal gland during development and onset of xerostomia in Sjogren's syndrome-like disease of the C57BL/6.NOD-Ae... OmicsDI

    ID: E-GEOD-48139

    Date Released: 07-14-2015

    Description: Recently, we reported the development of the C57BL/6.NOD-Aec1Aec2 mouse that carries two genetic intervals derived from the NOD mouse capable of confe...

  49. Expression data from NOD and C57BL/6 mouse pancreas CD8α- Dendritic Cells (DCs) under steady-state and after in-vitro LPS stimulation OmicsDI

    ID: E-GEOD-45028

    Date Released: 07-09-2015

    Description: Abstract Two major dendritic cell (DC) subsets have been described in the islets of mice: The immunogenic CD8α-CD11b+ DCs and the tolerogenic CD8α+...

  50. Expression profiling of the retinal pigment epithelium in zebrafish smarca4 mutant OmicsDI

    ID: E-GEOD-50241

    Date Released: 07-21-2015

    Description: Purpose: The purpose of this study was to develop a framework for analyzing RPE expression profiles from zebrafish eye mutants. Methods: The fish mo...

  51. Molecular-guided therapy predictions reveal drug resistance phenotypes and treatment alternatives in malignant peripheral nerve sheath tumors OmicsDI

    ID: E-GEOD-50208

    Date Released: 07-21-2015

    Description: Use existing public data, cell lines and patient tumors with a personalized medicine approach to predict effective therapies for treatment of Neurofib...

  52. Transcription profiling of human response to etanercept treatment in patients with Psoriasis OmicsDI

    ID: E-GEOD-11903

    Date Released: 07-21-2015

    Description: The success of TNF inhibitors for treatment of psoriasis and other inflammatory diseases was previously attributed to blockade of innate immunity. In...

  53. Expression data from E11.5 mouse branchial arch 1 (BA1) - comparison between Ezh2lox/lox and Wnt1Cre Ezh2lox/lox embryos OmicsDI

    ID: E-GEOD-52220

    Date Released: 07-23-2015

    Description: Conditional ablation of Ezh2 in the neural crest lineage results in loss of the neural crest-derived mesenchymal derivatives. In this data sheet we de...

  54. Whole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models OmicsDI

    ID: E-GEOD-46298

    Date Released: 07-16-2015

    Description: Microarray analysis has been applied to the study of ALS in order to investigate gene expression in whole spinal cord homogenates of SOD1 G93A mice an...

  55. Expression data from different photosynthetic rate in Populus. OmicsDI

    ID: E-GEOD-47105

    Date Released: 07-16-2015

    Description: Despite the significance of nucleus genes in plant growth and development, little is known of the molecular bases of regulation of photosynthesis in w...

  56. Transcription profiling by array of human nasal epithelium from patients infected with HRV-16 rhinovirus OmicsDI

    ID: E-GEOD-11348

    Date Released: 07-24-2015

    Description: This study provides a comprehensive evaluation of changes in gene expression during rhinovirus infections in vivo. Subjects were experimentally infect...

  57. TGF beta Dosage Experiment OmicsDI

    ID: E-GEOD-50968

    Date Released: 07-22-2015

    Description: Genome-wide expression data can provide important insights into normal and pathological cellular processes. However, the ability to use gene expressi...

  58. Identification of the Hha-dependent genes in Salmonella entrica serovar Typhimurium SL1344 OmicsDI

    ID: E-MTAB-3621

    Date Released: 07-27-2015

    Description: Transcriptomic analysis in Salmonella enterica serovar Thypimurium SL1344 mutant strains hha, stpA and point mutant D48N compared to wild type strain

  59. Characterization of Gene Expression in liver cell OmicsDI

    ID: E-GEOD-51951

    Date Released: 07-23-2015

    Description: The Human Agilent 60-mer, oligonucleotide microarray consists of a total of probes covering 41,096 genes of human. Through a validation study, total ...

  60. Treatment of renal cell carcinoma cell line A-498 with zebularine OmicsDI

    ID: E-GEOD-51627

    Date Released: 07-22-2015

    Description: Cultures of A-498 cells were treated for 120hours with 1000µM zebularine (SIGMA) in three independent biological experiments. Zebularine acts as a DN...

  61. Expression profiles from Drosophila melanogaster scrib and lgl mutant wing imaginal disc and brain complexes at day 9 after egg deposition (AED) versu... OmicsDI

    ID: E-GEOD-48852

    Date Released: 07-17-2015

    Description: mRNA microarray of Drosophila wing imaginal discs or brain complexes from lgl27S3/lglE2S31 (lgl-null), scrib1/scrib2 or wild-type 3rd instar larvae RN...

  62. Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells (Affymetrix) OmicsDI

    ID: E-GEOD-46493

    Date Released: 07-10-2015

    Description: The effects of diverse stresses on promoter selectivity and transcription regulation by the tumor suppressor p53 are poorly understood. We have taken ...

  63. Comparative gene expression analysis of the human periodontal ligament in deciduous and permanent teeth OmicsDI

    ID: E-GEOD-50640

    Date Released: 07-20-2015

    Description: There are histological and functional differences between human deciduous and permanent pediodontal ligament (PDL) tissues. The purpose of this study ...

  64. The complex pattern of epigenomic variation between natural yeast strains at single-nucleosome resolution OmicsDI

    ID: E-MTAB-3390

    Date Released: 07-20-2015

    Description: We investigated natural inter-individual variation of the epigenome in a quantitative manner. To probe the degree of natural epigenomic diversity in S...

  65. Crosstalk between the effects of extracellular vesicles (Evs) and TNF on U937 human monocyte cell line OmicsDI

    ID: E-GEOD-47897

    Date Released: 07-14-2015

    Description: Under physiological conditions, extracellular vesicles (EVs) are present simultaneously in the extracellular compartment together with cytokines. Thus...

  66. Common frog (Rana temporaria) transcriptomes following Exposure to Ranavirus and Batrachochytrium dendrobatidis OmicsDI

    ID: E-MTAB-3632

    Date Released: 07-10-2015

    Description: This experiment examined the transcriptional response of juvenile amphibian hosts (common frog, Rana temporaria) to two important amphibian pathogens:...

  67. Gene expression profiles of human blood cells OmicsDI

    ID: E-MTAB-3753

    Date Released: 07-16-2015

    Description: In this study, we performed genome-wide DNA methylation and transcriptome profiling of young obese individuals with controls (n = 6 and 6, respectivel...

  68. Runx3 function in splenic NK cells (IL-2 or IL-15) OmicsDI

    ID: E-GEOD-50122

    Date Released: 07-13-2015

    Description: NK cells are innate immune cells that recognize and kill foreign, virally-infected and tumor cells without the need for prior immunization. NK expansi...

  69. Identification of differentially expressed genes due to LBH589 treatment in aromatase inhibitor-resistant tumors OmicsDI

    ID: E-GEOD-47346

    Date Released: 07-13-2015

    Description: In order to validate the utility of a novel pathway algorithm (BD-Func), we test if an LBH589 signature based data from 3 cell lines (GSE36509) in an ...

  70. Transcriptional Profiling of Neuronal APP/APLP2 Double-Conditional Knockout Mice. OmicsDI

    ID: E-GEOD-48622

    Date Released: 07-15-2015

    Description: Gene expression analysis of 2-month-old APP/APLP2 double-conditional Knockout (N-dCKO) mice and littermate APLP2 knockout controls, APP knockout and w...

  71. Cross-species gene expression analysis of species-specific differences in preclinical assessment of pharmaceutical compounds (human) OmicsDI

    ID: E-GEOD-47970

    Date Released: 07-14-2015

    Description: Significant qualitative and quantitative differences exist between humans and the animal models used in research. However, significant quantitative an...

  72. Gene expression profiling of KLF5, GATA4 and GATA6 knock down in YCC3/AGS/KATOIII cell lines OmicsDI

    ID: E-GEOD-51704

    Date Released: 07-22-2015

    Description: Three transcription factors KLF5, GATA4 and GATA6 are recurrently amplified in multiple gastric cancer cohorts, representing one type of lineage-survi...

  73. Immune Response of Immature Dendritic Cells after Infection with Human Cytomegalovirus Strain TB40E OmicsDI

    ID: E-GEOD-14816

    Date Released: 07-24-2015

    Description: Microarray analysis and quantitative real-time PCR revealed that TB40E infection of DCs led to changes of the gene expression pattern. A variety of pr...

  74. Transcriptional profiling of nascent and mature pancreatic beta cells OmicsDI

    ID: E-MTAB-3351

    Date Released: 07-10-2015

    Description: This experiment used RNA-Seq technology to examine transcription profile in FACS-sorted MIP-EGFP+ mouse pancreatic cells at E16.5 (nascent beta cells)...

  75. Expression Data For BRD4 Inhibition OmicsDI

    ID: E-GEOD-50865

    Date Released: 07-20-2015

    Description: BRD4 Inhibition of spindle cell malignant peripheral nerve sheath tumor (sMPNST) tumor cells Cells were treated with Brd4 shRNA (3 days) or 500 nM JQ1...

  76. Expression data from OT-I CD8 T cells activated with DC in the presence or absence of CpG-Induced Inflammation OmicsDI

    ID: E-GEOD-53200

    Date Released: 07-30-2015

    Description: Inflammatory cytokines promote the accumulation of activated CD8 T cells. Here, we transfer 600 OT-I CD8 T cells iv into naïve C57BL/6 hosts. One d...

  77. The transitional Gene Expression Profiling of Ovarian Follicle Treated with Indomethacin and RU486 in Rats OmicsDI

    ID: E-GEOD-54584

    Date Released: 07-31-2015

    Description: Indomethacin (an inhibitor of prostaglandin synthesis) and RU486 (mifepristone, progesterone receptor antagonist) are well known compounds which impai...

  78. HIC2 is a novel dosage-dependent regulator of cardiac development within the distal 22q11 deletion syndrome region OmicsDI

    ID: E-GEOD-56430

    Date Released: 08-03-2015

    Description: Rationale: 22q11 deletion syndrome arises from recombination between low copy repeats on chromosome 22. Typical deletions result in hemizygosity for T...

  79. Identification of a blood-borne miRNA signature of synovial sarcoma OmicsDI

    ID: E-MTAB-3273

    Date Released: 08-03-2015

    Description: Synovial sarcomas account for approximately 10% of all soft-tissue tumors and occur most frequently in young adults. A specific translocation in this...

  80. Transcriptomic characterization of Hepatocellular Carcinoma with CTNNB1 mutation OmicsDI

    ID: E-GEOD-55048

    Date Released: 08-04-2015

    Description: We report transcritomic characterization of changes in CTNNB1 mutation positive HCCs in comparison to paratumoral tissues 4 pair of HCC and paratumora...

  81. Expression data from skin of bovines infested with ticks OmicsDI

    ID: E-GEOD-57907

    Date Released: 08-04-2015

    Description: The aim of this work was to access the early immune response triggered by R. microplus larvae attachment in previously selected resistant and suscepti...

  82. Concurrent DNA copy number alterations and mutations in genes related to maintenance of genome stability in uninvolved glandular tissue from breast ca... OmicsDI

    ID: E-MTAB-3110

    Date Released: 07-31-2015

    Description: Somatic mosaicism for DNA copy number alterations (SMC-CNA) is defined as gain or loss of chromosomal segments in mitotic cells within a single organi...

  83. Loss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons [NSC34] OmicsDI

    ID: E-GEOD-56503

    Date Released: 08-03-2015

    Description: Aims: Loss of nuclear TDP-43 characterises sporadic and most familial forms of amyotrophic lateral sclerosis (ALS). TDP-43 (encoded by TARDBP) has mul...

  84. Expression data from embryonic stem cells differentiation OmicsDI

    ID: E-GEOD-58960

    Date Released: 08-04-2015

    Description: Pluripotency-associated transcription factor Foxd3 is required for maintaining pluripotent cells. However, the molecular mechanisms underlying its fun...

  85. Linking Notch signaling to ischemic stroke OmicsDI

    ID: E-GEOD-58368

    Date Released: 08-04-2015

    Description: Using a hitherto uncharacterized knockout mouse model of Notch 3, a Notch signaling receptor paralogue highly expressed in vascular SMCs, we uncover a...

  86. Interplay of host microbiota, genetic perturbations, and inflammation promote local development of intestinal neoplasms in mice OmicsDI

    ID: E-GEOD-47735

    Date Released: 08-04-2015

    Description: The preferential localization of some neoplasms, such as serrated polyps, in specific areas of the intestine suggests that non-genetic factors may be ...

  87. Transcription profiling of brown adipose tissue from resistin-transgenic spontaneously hypertensive rats OmicsDI

    ID: E-MTAB-3787

    Date Released: 07-30-2015

    Description: Resistin has been originally identified as an adipokine that links obesity to insulin resistance in mice. In our previous studies in spontaneously hyp...

  88. Transcription profiling by array of human lymphocytes from prostate carcinoma patients after X-radiation treatment OmicsDI

    ID: E-TABM-90

    Date Released: 07-29-2015

    Description: For a case-control study, we selected 54 prostate carcinoma patients with no evidence of disease 2 years after curative

  89. Hepatocytes-HepaRG reprogramming. OmicsDI

    ID: E-GEOD-52989

    Date Released: 07-29-2015

    Description: To identify the molecular mechanisms and environmental inducers contributing to reprogramming of hepatocytes into progenitors in HCC context, we used ...

  90. The DNA Double-Strand Break Response Is Abnormal in Myeloblasts From Patients With Therapy-Related Acute Myeloid Leukemia OmicsDI

    ID: E-GEOD-52478

    Date Released: 07-29-2015

    Description: In order to examine if the upregulation of DNA repair genes on chromosome 8 was associated with the abnormal DSB phenotype observed in trisomy 8 (defi...

  91. Transcription profiling by array of human aortic vascular smooth muscle cells treated with IL-17 or untreated OmicsDI

    ID: E-GEOD-11367

    Date Released: 07-29-2015

    Description: Investigate the effect of recombinant human IL-17A on vascular smooth muscle cells cultured from human aortas. Experiment Overall Design: SMCs from th...

  92. miRNA expressions in non-cancerous and cancerous human gastric tissues OmicsDI

    ID: E-GEOD-23739

    Date Released: 07-28-2015

    Description: We investigated the involvement of microRNAs (miRNAs) in gastric cancers. MiRNA expression was profiled from 40 cancerous and 40 non-cancerous tiss...

  93. BUTYRATE ENEMAS ON PATIENTS WITH ENTEROSTOMY OmicsDI

    ID: E-MTAB-2436

    Date Released: 07-27-2015

    Description: The aim of this study was to evaluate the effects of sodium butyrate enemas on the mucosal genes expression profiles of patients with an enterostomy.

  94. Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast OmicsDI

    ID: E-GEOD-20086

    Date Released: 07-27-2015

    Description: Twenty-one genes (27 probe sets) were up-regulated in CAF, as compared with NF. Known functions of these genes relate to paracrine or intracellular si...

  95. The transcriptional repressor BLIMP1 curbs host-defenses by suppressing expression of the chemokine CCL8 OmicsDI

    ID: E-GEOD-53145

    Date Released: 07-30-2015

    Description: The transcriptional repressor BLIMP1 is a master regulator of B and T cell differentiation. To examine the role of BLIMP1 in innate immunity we used a...

  96. Hematopoietic stem cells from mice treated with G-CSF or saline alone for 36 hours OmicsDI

    ID: E-GEOD-55093

    Date Released: 07-31-2015

    Description: Recent studies demonstrate that inflammatory signals regulate hematopoietic stem cells (HSCs). Granulocyte-colony stimulating factor (G-CSF) is often...

  97. Transcription profiling of MCF-7 cells overexpressing phosphodiesterase type 5 (PDE5) OmicsDI

    ID: E-MTAB-3801

    Date Released: 08-04-2015

    Description: Purpose: By catalyzing hydrolysis of cyclic guanosine monophosphate, phosphodiesterase (PDE) 5 is a critical regulator of its concentration and biolog...

  98. Expression from hemocytes misexpressing Idh-R195H vs. controls OmicsDI

    ID: E-GEOD-62008

    Date Released: 08-05-2015

    Description: Expression profile for hemocytes from hml-Gal4, UAS-2xEGFP larvae were compared to hemocytes from hml-Gal4, UAS-2xEGFP; UAS-Idh-R195H larvae We sought...

  99. Transcription profiling by array of human monocyte-derived dendritic cells treated with 1,25-dihydroxyvitamin D3 OmicsDI

    ID: E-GEOD-13762

    Date Released: 07-29-2015

    Description: We have carried out global gene expression analysis to clarify the interrelationship between 1,25-dihydroxyvitamin D3 and differentiation-driven gene ...

  100. Genome-wide characterization of gene regulatory mechanisms in Shh pathway underlying the pattern formation of early mouse brain OmicsDI

    ID: E-MTAB-2008

    Date Released: 07-29-2015

    Description: Shh and its receptor Ptch1 define two adjacent mutually exclusive domains: Shh+Ptch1- and Shh-Ptch1+ of E11.5 mouse brain. Gata3 ChIP-seq experiments ...


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